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Preface
Third International Meeting on the Molecular Mechanisms of
Metal Toxicity and Carcinogenicity
Max Costa, Maria A. Zoroddu, William A. Suk, Claudia Thompson,
and Toby Rossman
p. 687 [HTML] [Download
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Metal Transport
Transport of Toxic Metals by Molecular Mimicry
Nazzareno Ballatori
p.689 [HTML] [
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Molecular Mechanism of Copper Transport in Wilson Disease
Negah Fatemi and Bibudhendra Sarkar
p. 695 [HTML] [
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Brain Uptake, Retention, and Efflux of Aluminum and Manganese
Robert A. Yokel
p. 699 [HTML] [
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Chemistry and Biochemistry
of Metals
Use of XAS for the Elucidation of Metal Structure and Function:
Applications to Nickel Biochemistry, Molecular Toxicology, and
Carcinogenesis
Paul E. Carrington, Faizah Al-Mjeni, Maria A. Zoroddu, Max
Costa, and Michael J. Maroney
p. 705 [HTML] [
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Formation of Reactive Nitrogen Species at Biologic Heme Centers:
A Potential Mechanism of Nitric Oxide-Dependent Toxicity
Luigi Casella, Enrico Monzani, Raffaella Roncone, Stefania
Nicolis, Alberto Sala, and Antonio De Riso
p. 709 [HTML] [
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Structure and Potential Mutagenicity of New Hydantoin Products
from Guanosine and 8-Oxo-7,8-Dihydroguanine Oxidation by Transition
Metals
Cynthia J. Burrows, James G. Muller, Olga Kornyushyna, Wenchen
Luo, Victor Duarte, Michael D. Leipold, and Sheila S. David
p. 713 [HTML] [
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Molecular Mechanisms in Nickel Carcinogenesis: Modeling Ni(II)
Binding Site in Histone H4
Maria Antonietta Zoroddu, Laura Schinocca, Teresa Kowalik-Jankowska,
Henryk Kozlowski, Konstantin Salnikow, and Max Costa
p. 719 [HTML] [
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Chromate
Carcinogenesis
Guanine and 7,8-Dihydro-8-Oxo-Guanine-Specific Oxidation in
DNA by Chromium(V)
Kent D. Sugden and Brooke D. Martin
p. 725 [HTML] [
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Reductive Activation with Cysteine Represents a Chromium(III)-Dependent
Pathway in the Induction of Genotoxicity by Carcinogenic Chromium(VI)
Anatoly Zhitkovich, George Quievryn, Joseph Messer, and Zhanna
Motylevich
p. 729 [HTML]
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Metabolic Pathways of Carcinogenic Chromium
Elena Gaggelli, Francesco Berti, Nicola D’Amelio, Nicola
Gaggelli, Gianni Valensin, Lucia Bovalini, Alessandro Paffetti,
and Lorenza Trabalzini
p. 733 [HTML]
[
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Chromate-Induced Epimutations in Mammalian Cells
Catherine B. Klein, Lin Su, Darlene Bowser, and Joanna Leszczynska
p. 739 [HTML] [
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Arsenic Carcinogenesis
Arsenate Reductases in Prokaryotes and Eukaryotes
Rita Mukhopadhyay and Barry P. Rosen
p. 745 [HTML]
[
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Arsenite Cocarcinogenesis: An Animal Model Derived from Genetic
Toxicology Studies
Toby G. Rossman, Ahmed N. Uddin, Fredric J. Burns, and Maarten
C. Bosland
p. 749 [HTML] [
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Oxidative DNA Adducts and DNA–Protein Cross-Links Are
the Major DNA Lesions Induced by Arsenite
Da-Tian Bau, Tsu-Shing Wang, Chiao-Hui Chung, Alexander S.S. Wang,
and Kun-Yan Jan
p. 753 [HTML] [
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The Molecular Mechanisms of Arsenic-Induced Cell Transformation
and Apoptosis
Zigang Dong
p. 757 [HTML] [
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Sodium Arsenite-Induced Stress-Related Gene Expression in
Normal Human Epidermal, HaCaT, and HEL30 Keratinocytes
Kevin J. Trouba, Kristen M. Geisenhoffer, and Dori R. Germolec
p. 761 [HTML] [
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The Role of Biomethylation in Toxicity and Carcinogenicity
of Arsenic: A Research Update
Miroslav St´yblo, Zuzana Drobná, Ilona Jaspers,
Shan Lin, and David J. Thomas
p. 767 [HTML] [
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Mutagenic and Epigenetic
Mechanisms of Carcinogenesis
Fanconi Anemia Complementation Group A Cells Are Hypersensitive
to Chromium(VI)-Induced Toxicity
Susan K. Vilcheck, Travis J. O’Brien, Daryl E. Pritchard,
Linan Ha, Susan Ceryak, Jamie L. Fornsaglio, and Steven R. Patierno
p. 773 [HTML]
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Chiral Discrimination in Platinum Anticancer Drugs
Michele Benedetti, Jaroslav Malina, Jana Kasparkova, Viktor
Brabec, and Giovanni Natile
p. 779 [HTML]
[
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Enhanced Overexpression of an HIF-1/Hypoxia-Related Protein
in Cancer Cells
Hakan Cangul, Konstantin Salnikow, Herman Yee, David Zagzag,
Therese Commes, and Max Costa
p. 783 [HTML] [
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Distinct Mechanisms of Oxidative DNA Damage Induced by Carcinogenic
Nickel Subsulfide and Nickel Oxides
Shosuke Kawanishi, Shinji Oikawa, Sumiko Inoue, and Kohsuke Nishino
p. 789 [HTML]
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The Prospective Role of Abnormal Methyl Metabolism in Cadmium
Toxicity
Lionel A. Poirier and Tatyana I. Vlasova
p. 793 [HTML] [
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Interference by Toxic Metal Ions with DNA Repair Processes
and Cell Cycle Control: Molecular Mechanisms
A. Hartwig, M. Asmuss, I. Ehleben, U. Herzer, D. Kostelac, A.
Pelzer, T. Schwerdtle, and A. Bürkle
p. 797 [HTML] [
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Cysteine-Modifying Agents: A Possible Approach for Effective
Anticancer and Antiviral Drugs
Angela Casini, Andrea Scozzafava, and Claudiu T. Supuran
p. 801 [HTML] [
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Signal Transduction
and Effects on Gene Expression
Signaling from Toxic Metals to NF- B
and Beyond: Not Just a Matter of Reactive Oxygen Species
Fei Chen and Xianglin Shi
p. 807 [HTML] [
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Activation of Gene Expression by Metal-Responsive Signal Transduction
Pathways
Timothy K. Adams, Nurten Saydam, Florian Steiner, Walter Schaffner,
and Jonathan H. Freedman
p. 813 [HTML] [
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Attenuation of Nuclear Factor Kappa B (NF-B)
Promotes Apoptosis of Kidney Epithelial Cells: A Potential Mechanism
of Mercury-Induced Nephrotoxicity
James S. Woods, Francisco J. Dieguez-Acuña, Maureen
E. Ellis, John Kushleika, and P. Lynne Simmonds
p. 819 [HTML] [
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Cell Signaling and Cytotoxicity by Peroxynitrite
Orazio Cantoni, Letizia Palomba, Andrea Guidarelli, Ilaria Tommasini,
Liana Cerioni, and Piero Sestili
p. 823 [HTML] [
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Suppression of Metallothionein-I/II Expression and Its Probable
Molecular Mechanisms
Samson T. Jacob, Sarmila Majumder, and Kalpana Ghoshal
p. 827 [HTML] [
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Nickel Carcinogenesis
The Role of Hypoxia-Inducible Signaling Pathway in Nickel
Carcinogenesis
Konstantin Salnikow, Todd Davidson, and Max Costa
p. 831 [HTML]
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Activation of Nuclear Factor-B
and Not Activator Protein-1 in Cellular Response to Nickel Compounds
Yi Huang, Gerard Davidson, Jingxia Li, Yan Yan, Fei Chen, Max
Costa, Lung Chi Chen, and Chuanshu Huang
p. 835 [HTML] [
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Respiratory Carcinogenicity Assessment of Soluble Nickel Compounds
Adriana R. Oller
p. 841 [HTML] [
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Molecular Biology of Deregulated Gene Expression in Transformed
C3H/10T1/2 Mouse Embryo Cell Lines Induced by Specific Insoluble
Carcinogenic Nickel Compounds
Joseph R. Landolph, Anuradha Verma, Jamuna Ramnath, and Farrah
Clemens
p. 845 [HTML]
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Neurotoxicity and
Immunotoxicity
Silent Latency Periods in Methylmercury Poisoning and in Neurodegenerative
Disease
Bernard Weiss, Thomas W. Clarkson, and William Simon
p. 851 [HTML] [
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Cognitive Deficits and Changes in Gene Expression of NMDA
Receptors after Prenatal Methylmercury Exposure
Mario Baraldi, Paola Zanoli, Fabio Tascedda, Joan M.C. Blom,
and Nicoletta Brunello
p. 855 [HTML] [
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Investigations of Methylmercury-Induced Alterations in Neurogenesis
Elaine M. Faustman, Rafael A. Ponce, Ying C. Ou, Ma. Aileen C.
Mendoza, Thomas Lewandowski, and Terrance Kavanagh
p. 859 [HTML]
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Induction of Apoptosis in Mammalian Cells by Cadmium and Zinc
Wim Wätjen, Hajo Haase, Marta Biagioli, and Detmar Beyersmann
p. 865 [HTML] [
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Possible Involvement of Copper(II) in Alzheimer Disease
Teresa Kowalik-Jankowska, Monika Ruta-Dolejsz, Kornelia Wisniewska,
Leszek Lankiewicz, and Henryk Kozlowski
p. 869 [HTML]
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A Role for Associated Transition Metals in the Immunotoxicity
of Inhaled Ambient Particulate Matter
Judith T. Zelikoff, Kimberly R. Schermerhorn, Kaijie Fang,
Mitchell D. Cohen, and Richard B. Schlesinger
p. 871 [HTML]
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Mercury-Induced Autoimmunity in Mice
Jesper Bo Nielsen and Per Hultman
p. 877 [HTML] [
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Environmental Metal
Toxicity and Treatment
Pathology Related to Chronic Arsenic Exposure
Jose A. Centeno, Florabel G. Mullick, Leonor Martinez, Norbert
P. Page, Herman Gibb, David Longfellow, Claudia Thompson, and
Elena R. Ladich
p. 883 [HTML] [
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Molecular Mechanisms of in Vivo Metal Chelation: Implications
for Clinical Treatment of Metal Intoxications
Ole Andersen and Jan Aaseth
p. 887 [HTML]
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