Available
in PDF
In this issue...
Genome Project
 U.S.
HGP on Fast Track
DOE
Joint Genome Institute Exceeds Goal
New
5-Year Goals
Faster
Sequencing with BACs
Mapping
with STCs and STSs
Availability
of BAC Clones and STC Data
BAC
Related Websites
BAC
Resource Success Story
Scientists
Hunt SNPs for Variation, Disease
Who's
Sequencing the Human Genome?
Genomics
Progress in Science
EMSL
Promotes Remote Access to Instrumentation
Second
Private-Sector Sequencing Project
GeneMap'98
In the News
Team
Delivers C. elegans Sequence
Why
Sequence Entire Genomes? Worm's Eye View
Embnet.news on
Web
European
Biotech Program
DOE
BER Research Update
Hollaender
Fellows Named
SBIR
1998 Human Genome Awards Announced
Mouse
Resources
Mouse
Consortium for Functional Genomics
Chlamydia Genome
Analysis
HUGO
Merges Offices, Web Sites
Microbial Genomics
Superbug Deinococcus
radiodurans
Unfinished
Microbial Genomes Searchable
TIGR
Releases Chlorobium tepidum Sequence
DOE
MGP Abstracts Online
Microbial
TV Series
Ethical, Legal, and Social Issues
and Educational Resources
Cambridge
ELSI Symposium
Eric
Lander, Genetics in the 21st Century
Mark
Rothstein, Genetic Privacy
James
Wilson, Gene Therapy Present & Future
LeRoy
Walters, Ethical Issues in Gene Therapy
DNA
Files on NPR, Internet
Innovative
Biotechnology Curriculum
Short
Course for Biology Teachers
Microbial
TV Series
Proteomics
Looking
at Proteins to Understand Expression
2-DGE: Protein
Visualization, Modification
Tool
for Protein Analysis
TREMBL
Release 6
R&D
100 Award Goes to LANL's SOLVE
NIH
Awards Proteomics Grant to Axys
E.
coli Proteome Database
Genetics in Medicine
National
Organization for Rare Disorders
Translation
of Genetics to Medicine: New Website
Cancer
Genetics Web Site
HuGem
Website Offers Education in New Genetics
Calculation
of Genetic Risks 2nd Edition
New Genetics
Manual Offered
Mutation
Research Genomics Online
Informatics
GDB
Database Operations Restored
In
Silico Biology: Bioinformatics Journal
Computational
Methods Book Available
Bioinformatics
Guide
BioToolKit
Gene-Finding
Programs at Sanger
New
Sequin Version
Tandem
Repeat Tool
Sequence
Viewer
SmithKline
Licenses Gene Logic Software
Influenza
Database at LANL
TRANSFAC
Database
p53
Mutation Database
TBASE
at Jackson Laboratory
Intein
Database on Web
System
Identifies Polymorphisms
Web, Other Resources, Publications
1999
Oakland Workshop Website
Launchpad
to Human Chromosomes
Nature
Genetics Supplement
Funding
DOE
Office of Science Grants and Contracts
NHGRI
National Service Award Fellowships
NCI
Technologies for Molecular Analysis
NIH:
Netork for Large-Scale Mouse Sequencing
NHGRI:
Genomic Technology Development
US
Genome Research Funding
Meeting Calendars & Acronyms
Genome
and Biotechnology Meetings
Training
Courses and Workshops
Acronyms
 HGN archives
and subscriptions
HGP
Information home
|
Software Programs Provide Useful Resources
BioToolKit now provides 750 annotated links to Web tools for the study of nucleic acid, genome, and protein structure.
Updated versions of gene-finding programs (including FGENES, FGENESH, and FGENES-m variant for mammalian sequences) are available for use through the Sanger Web site. Also, the Gapped BLASTP program from the National Center for Biotechnology Information allows users to check a gene's protein structure in the INFOGENEP database of finished and unfinished human sequences and receive the clone's name and sequence. See the Web site for more information.
The National Center for Biotechnology Information has released Version 2.80 of Sequin, the sequence-submission and editing tool, for all platforms. This version is expected to be particularly useful for genome centers that annotate large records.
Gary Benson (Mount Sinai School of Medicine) has developed a program to find tandem repeats in DNA sequence data without prior knowledge of pattern repeat, pattern size, or number of copies. The current version finds pattern repeats ranging from 1 to 500 bases.
Users submitting a sequence (up to 2 Mb) in FASTA format will receive a summary table of repeats, including their location, size, number of copies, and nucleotide content. Clicking on an entry shows alignment against a consensus pattern, allowing the user to see the repeat pattern and mutation location.
Sequence Viewer, a free public software tool for viewing and analyzing DNA sequences, is available on the National Center for Genome Resources (NCGR) Web site. The NCGR tool was developed to fill the need for graphical representations of nucleotide sequences in the Genome Sequence DataBase and for detailed descriptions of sequence annotation. Sequence Viewer allows users to quickly find a sequence region that integrates with a gene rather than searching through a lengthy, complex flat-file report. It also can be used as a quality-control tool for readily locating mistakes in feature position.
The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n1-2).
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