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Human Genome News Archive Edition

Vol.10, No.3-4   October 1999 
Available in PDF 
 
In this issue... 

DOE '99 Oakland Highlights
* Meeting Intro
* HGP Progress, Challenges
* Joint Genome Institute
*
JGI Facility Opening
*
Sequencing
*
Device Speeds Sequencing
* Chromosome 19 Genes
* Functional Genomics
* Sample Prep System
* Informatics
* Education & Bioethics
* Microbial Genomes
* Next Meeting Feb. 2000

Genome Project
* Accelerated Timetable
* FY1999 Budgets
* JGI Refits Facility
* Progress

In the News 
* Drosophila Near Completion
* Directors, Researchers Receive Awards
* Chromosomes 21, 22 Near Finish
* Human MHC Region Sequenced
* Mouse Probes Aid Mapping
* Genetic Testing Committee
* DOE Labs & Biomedicine
* Biomedical Engineering Proposals
* Drug Firms Create SNP Resource
* SBIR 1999 Awards
* HUGO News
* 1999 Hollaender Winners

Microbial Genomics 
* EcoCyc Database for E. coli
* Developing EcoCyc
* Thermotoga Sequence
* Clostridium Sequenced
* Microbial Gene Finder
* Neisseria Sequence
* Microbial Web Sites

Ethical, Legal, and Social Issues
* Education, Counseling Foundation
* ELSI Studies
* ELSI Retrospective
* Protecting Privacy

Informatics 
* MGI 2.2 Released
* DNA Repository

Web, Other Resources, Publications 
* Metabolic Pathways
* New Staden Package
* PDB Newsletter
* Polymorphism Database
* Bacterial Protein Database
* DOE BER Publications
* HGP Information Web
* Biotechnology Business Webs
* Behavioral Genetics
* Office of Science Reports
* Articles on Genetics

Funding 
* Genome Research Funding

Meeting Calendars & Acronyms 
* Genome & Biotech Meetings 
* Training Courses & Workshops 
* Acronyms 


*HGN archives & subscriptions 
*HGP Information home

Education and Bioethics

Report from 1999 DOE Genome Meeting

The Ethical, Legal, and Social Issues (ELSI) components of the U.S. Human Genome Project represent the world's largest bioethics undertaking. DOE's ELSI Program focuses on genetic education, privacy, fair use of personal genetic information, and genetics and the workplace. Presentations of two ELSI grantees are reported below.

Revealing DNA Differences

David Micklos (Cold Spring Harbor Laboratory, CSHL) described a program to introduce high school biology teachers to a laboratory-based unit on human DNA polymorphisms, which can be useful in disease diagnosis, forensic identification, and other applications. In addition to teaching the science, the program provides a personal perspective that enhances discussion of the uses and potential abuses of genetic technology. [Ready-to-use teaching kits developed at CSHL to support this program are available through Carolina Biological Supply Company (800/331-5551, www.carosci.com).]

Other DOE-funded educational programs initiated at CSHL include a mitochondrial DNA sample-processing service that sequences student DNA samples and posts the data to an Internet-based sequence server (http://www.bioservers.org/bioserver/). Step-by-step directions allow students to use their own data to find related sequences in GenBank, compare themselves to other people, and test whether or not Neanderthal hominids were direct ancestors of modern humans. Micklos demonstrated the Bioform program (http://genepro.cshl.org/bioforms/). With this program, students can analyze mitochondrial sequences to identify the remains of the last Russian czar and his family and determine whether Anna Anderson was the missing princess Anastasia, as she claimed.

Importance of Microbes

Jeroo Kotval (U. of Albany), Cynthia Needham (Microbial Literacy Coll.), Sara Tobin (Stanford)Microbes can teach people much, since all living things today evolved from them and still share fundamental biological properties with them. Such is the message of Intimate Strangers: Unseen Life on Earth, a four-part science documentary developed for public television with the support of the DOE Human Genome and Microbial programs. Cynthia Needham described this and other educational efforts that make up the Microbial Literacy Collaborative, a partnership of organizations committed to advancing scientific literacy through a focus on the microbial world.

Needham reported on four components of the initiative: the science documentary, a set of 17 hands-on community-based microbial activities, a youth leadership training program for precollege students from traditionally underrepresented communities, and a 12-part telecourse for undergraduates. Intimate Strangers will air on many PBS stations for four consecutive Tuesdays beginning Nov. 9 at 8p.m. (check local listings). Microbe World, an interactive Web site, was designed to build on the themes of all these activities (www.microbeworld.org).


The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n3-4).

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