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United States Department of Veterans Affairs
National HIV/AIDS Program
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Drug Dosing Toolkit

Fuzeon (enfuvirtide, T-20)

Type of Drug: Fusion Inhibitor
Fusion inhibitors work by stopping the HIV virus from getting into your body's healthy cells in the first place.

Approved adult dosing

90 mg (in 1 mL solution) injection

one injection under the skin, two times a day

  • Morning

    Fuzeon

    Fuzeon

  • Evening

    Fuzeon

    Fuzeon

Notes on taking this medication

  • One vial contains a white powder, which is the medication (Fuzeon); another vial contains sterile water; withdraw the water with a syringe and mix into the vial with the Fuzeon
  • You can prepare both doses at the same time, but should store the second vial in a refrigerator for use later on the same day
  • Keep uncapped vial tops, syringes, and your hands clean while preparing Fuzeon
  • Draw Fuzeon solution into the syringe only when you are ready to inject
  • Rotate injection sites for each injection
  • Never inject Fuzeon into a vein or muscle

Side effects

  • At injection site: redness; pain or tenderness; swelling; bumps; hardening of skin
  • Very rare serious allergic reactions: symptoms include trouble breathing; fever with vomiting and rash; swollen feet

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer:

This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.