Drug Dosing Tool: Atripla (U.S. Department of Veterans Affairs)

Atripla (Sustiva + Viread + Emtriva)

Type of Drug: Fixed-Dose Combination

Fixed-dose combinations combine the most commonly prescribed doses of several medications into 1 pill.

Approved adult dosing

Sustiva 600 mg + Viread 300 mg + Emtriva 200 mg in a single tablet

one tablet, once a day

Daily
Atripla

Notes on taking this medication

Take at bedtime
Take on an empty stomach
Sustiva component interacts with many other drugs; consult your medical provider
Persons with kidney problems may need an adjustment to their doses of the component drugs, and have to take them separately, not as a single pill

Same side effects as

Sustiva

Sleep disturbances such as vivid dreams (improves over the first several weeks); dizziness; drowsiness; mood disturbances
Difficulty with concentration
Rash
Do not take during pregnancy; may cause birth defects

Viread

Gassiness; abdominal discomfort; nausea; diarrhea
Kidney impairment
Viread is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

Emtriva

Skin discoloration (particularly in dark-skinned people)
Headache; diarrhea; nausea
Emtriva is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B

See accompanying chart: Tips for Common Side Effects

My doctor's instructions

Disclaimer:

This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist.

Drug Dosing Toolkit