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Metabolic Profiling: Applications To Toxicology & Risk ReductionMay 14 - 15, 2003
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| WEDNESDAY, MAY 14, 2003 | |
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| 8:40 | Metabonomics: Of Mice, Men and Sacred Cows John Connelly, Director of Biomedical Sciences, Metabometrix Ltd. |
| SCIENTIFIC SESSIONS | |
| 10:00 - 12:20 | APPLICATION TO TOXICOLOGY Chair: Ray Tennant, Director, National Center for Toxicogenomics, NIEHS Tennant Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/tennant.pdf)  (4.2 MB) Application of Metabonomic Technology to Drug Safety Evaluation Don Robertson, Pfizer Global Research and Development Monitoring The Toxicity of a Candidate Pharmaceutical and Identifying Biomarkers: A Metabonomics Approach Robert Plumb, Waters Corporation Plumb Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/plumb.pdf) (445 KB) Susan Sumner, Staff Scientist, Paradigm Genetics, Inc. The Consortium for Metabonomic Toxicology (COMET) Hector C. Keun, Biological Chemistry, Biological Sciences Division, Imperial College, University of London, UK |
| 1:20 – 3:40 | APPLICATION TO RISK REDUCTION Chair: Kenneth Ramos, Professor and Chair, Department of Biochemistry and Molecular Biology, University of Louisville Health Sciences Center Ramos Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/ramos.pdf) (275 KB) Biochemical Profiling of Lipids – Application to Direct Development and Toxicology Steve Watkins, President, Lipomics Technologies, Inc. Watkins Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/watkins.pdf) (1.1 MB) Developing Risk Reduction Strategies Through Metabolic Profiling Paul N-W Lee, Director, Biomedical Mass Spectroscopy Facility & Professor, Dept of Pediatrics, Harbor-UCLA Medical Center Lee Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/lee.pdf) (145 KB) Metabolic Analysis and Signatures in Patients with Amyotrophic Lateral Sclerosis Rima Kaddurah-Daouk, Metabolon, Inc. and Dana-Farber Cancer Institute Comprehensive Metabonomics: An Essential Tool for Assessing the Safety, Equivalence and unintended Effects of New Agricultural and Pharmaceutical Products Shawn Ritchie, Post Doctoral Research Associate - Oncology, Phenomenome Discoveries, Inc. |
| 6:30 | Dinner and Keynote Speaker (by invitation) Understanding the Continuum of Metabolism and Gene-Disease Relationships in Man and Animals Jeremy Nicholson, Professor and Head of Biological Chemistry, Imperial College, University of London, UK |
| THURSDAY, MAY 15, 2003 | |
| SCIENTIFIC SESSIONS | |
| 8:15 - 9:15 | Building With a Scaffold Trey Ideker, Pfizer Computational Biology Fellow, Whitehead Institute/MIT |
| 9:30 - 11:50 | COMPUTATIONAL AND SYSTEMS BIOLOGY Chair: David Rocke, Department of Applied Science, College of Engineering, University of California, Davis Rocke Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/rocke.pdf) (154 KB) Metabonomic Strategies for Modeling and Interpreting Complex Biological Data Elaine Holmes, Lecturer in Biological Chemistry, Biomedical Sciences Division, Imperial College, University of London, UK Computational Support for Metabonomics: Databases, Analysis and Visualization Pedro Mendes, Research Assistant Professor, Virginia Bioinformatics Institute Mendes Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/mendes.pdf) (405 KB) Multivariate Analysis of Metabonomics Data Cristopher Ambrozic, Director, Sales & Marketing, North America, Umetrics, Inc. Ambrozic Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/ambrozic.pdf) (154 KB) Impact of Food on Health: Linking Genomics, Nutrition and Health Research Elwin Verheij, Analytical Systems Biology, TNO Pharma, Netherlands |
| 12:50 - 1:50 | Metabolic Profiling: An FDA Perspective James MacGregor, Deputy Director, Washington Operations National Center for Toxicological Research, FDA MacGregor Presentation (http://www.niehs.nih.gov/news/events/pastmtg/2003/mpat/docs/macgreg.pdf) (1.3 MB) |
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