In the News
Genomes to Life
OASCR and GTL
DOE Microbial Cell Project
Human Genome Draft
Genome Perspective
Honor for DeLisi
New NIH Institute
Structural Genomics
Imaging Structures
Synchrotron Use
Proteome Organisation
Breast Cancer Research
Gene Expressions Used
Nuclear Medicine
Nuclear Medicine Labs
Toxicogenomics Center
Kettering Prize
Zeta Phi Beta Conference
Microbial Genomes
Sloan-DOE Fellowships
Ribosomes Illuminated
In Memoriam: Walter Goad

Comparative Genomics
Model Organism Studies
Sushi Delicacy
Arabidopsis Sequence
AAAS Prize
Microbial Conference
Flyer; "Microbe Month"
VISTA Software
Mouse
ORNL Mouse Program
MicroCAT Scanner Used
Draft Sequence Achieved
NCBI Mouse Resources
Human-Mouse Comparisons
MGI Allele Searching

Web, Publications, Resources
Next-Generation Computing
HGMIS Resources
NSF QSB Report
Structural Biology Basics
Minorities and the HGP
HGP Educational Kit
Testing, Counseling Resources
Biotech, ELSI Websites
Biotech Encyclopedia
ASM Report
Nature Yearbook
Next Wave Publication
High-School Curriculum
Education CD-ROMs
Exploring DNA in the Classroom

Funding
US Genome Research Funding
UK Scholarships, PostDocs

Meeting Calendars & Acronyms
Genome and Biotechnology Meetings
Training Courses and Workshops
Acronyms

HGN archives and subscriptions

Human Genome Project Information home

Imaging Biological Structures

Because molecular shape often provides clues to function in biological systems, obtaining a detailed knowledge of structure can help elucidate the basic principles of cell and organism function and the role of faulty structures in disease. A broad collection of structural data will provide valuable information beyond that available from individual structures and will have applications in the life sciences, biotechnology, and medicine.

Key advances making structural genomics research possible include the availability of synchrotrons and high-field NMR (nuclear magnetic resonance) instruments; the MAD (multiwavelength anomalous diffraction) method of phase determination; high-throughput cloning and recombinant expression; a flood of information from genome sequencing projects; and bioinformatics methods for protein-fold assignment, model building, and function prediction.

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v11n3-4).