Last Updated: 05/29/08
Meeting:
"Preoperative Therapy in Invasive Breast Cancer: Reviewing the State of the Science and Exploring New Research Directions"
March 26-27, 2007
Natcher Conference Center
Meeting description
Agenda with Video and Audio, Transcripts, and Presentation Slides
Flyer
Faculty list
MEETING DESCRIPTION:
Purpose: Preoperative therapy is increasingly being administered to women with breast cancer. Controversies exist, however, regarding optimal approaches.
This NCI-sponsored conference sought to determine the state of the science regarding clinical use of preoperative therapy in breast cancer, as well as identify future research agendas. Questions addressed by this meeting included the following:
- What is established in the field of preoperative therapy for invasive breast cancer?
- How should what is known be properly applied?
- How should preoperative therapy be incorporated into research initiatives?
Leading breast cancer physicians presented the state of the science and engaged in a panel discussion in which audience participation was encouraged.
AGENDA:
DAY 1: MONDAY, MARCH 26, 2007
8:00 am to 6:00 pm
Welcome and introductions
| Time | Title |
|---|---|
| 8:00-8:10 AM | Welcome and purpose of conference Eric Winer, M.D., Dana-Farber Cancer Institute Julie Gralow, M.D., University of Washington School of Medicine Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 8:10-8:25 AM | Conference overview and importance of conference James Doroshow, M.D., National Cancer Institute Cokie Roberts, Senior News Analyst, NPR and ABC News Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
Session I: Overview, and issues prior to breast cancer preoperative therapy
Moderators:
Jeffrey Abrams, M.D., National Cancer Institute
Laura Esserman, M.D., MBA, University of California, San Francisco
| Time | Title |
|---|---|
| 8:25-8:40 AM | Preoperative therapy - An overview William Wood, M.D., Emory University School of Medicine Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 8:40-8:55 AM | Which patients are candidates for preoperative therapy,
from a clinical (medical and surgical) perspective? Which are the optimal candidates? Gabriel N. Hortobagyi, M.D., F.A.C.P., M. D. Anderson Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 8:55-9:10 AM | Initial pathology assessment prior to preoperative
therapy
Baljit Singh, M.B.B.S., M.D., New York University Medical Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 9:10-9:30 AM | Imaging the breast before preoperative therapy Constance D. Lehman, M.D., Ph.D., University of Washington School of Medicine Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 9:30-9:50 AM | Evaluating the axilla and other nodal areas
with non-invasive techniques
Nagi Khouri, M.D., Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 9:50-10:25 AM | Pro's and con's of sentinel node biopsy pre- vs. post- preoperative therapy in operable disease
Pro-post-therapy: Terry Mamounas, M.D., MPH, Aultman Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts Pro-pre-therapy: Jay Harris, M.D., Dana-Farber Cancer Institute/Brigham and Women's Hospital Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 10:25-10:50 AM | Question & Answer for Session I Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 10:50-11:05 AM | COFFEE BREAK |
Session II: Systemic preoperative therapy for breast cancer
Moderators:
Nancy Davidson, M.D., Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center
Larry Norton, M.D., Memorial Sloan-Kettering Cancer Center
| Time | Title |
|---|---|
| 11:05-11:30 AM | NSABP Protocols B-18 and B-27: An update Norman Wolmark, M.D., National Surgical Adjuvant Breast and Bowel Project (NSABP) Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 11:30-11:55 AM | Some relevant points of the European Experience in preoperative chemotherapy Luca Gianni, M.D., Istituto Nazionale Tumori, Milan Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 11:55 AM-12:15 PM | Preoperative biologic therapy - anti-HER2 agents Aman Buzdar, M.D., M. D. Anderson Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 12:15-12:30 PM | Preoperative biologic therapy - anti-angiogenic agents Lisa Carey, M.D., University of North Carolina at Chapel Hill Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 12:30-1:25 PM | LUNCH BREAK |
| 1:25-1:40 PM | Preoperative treatment of the triple-negative (basal phenotype) breast cancer Judy E. Garber, M.D., MPH, Dana-Farber Cancer Institute Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 1:40-2:00 PM | Preoperative hormonal therapy Ian Smith, M.D., Royal Marsden Hospital, London Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 2:00-2:25 PM | Question & Answer for Session II Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
Session III: Evaluating response to breast cancer preoperative therapy
Moderators:
Edith A. Perez, M.D., Mayo Clinic Jacksonville
George W. Sledge, Jr., M.D., Indiana University School of Medicine
| Time | Title |
|---|---|
| 2:25-2:45 PM | Breast imaging to monitor the response to therapy Nola Hylton, Ph.D., University of California, San Francisco Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 2:45-3:05 PM | Pathologic assessment of the breast and axilla after preoperative therapy W. Fraser Symmans, M.D., M. D. Anderson Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 3:05-3:25 PM | Appropriate endpoints in clinical trials and markers for long-term clinical outcome Antonio C. Wolff, M.D., Johns Hopkins University, Sidney Kimmel Comprehensive Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 3:25-3:40 PM | COFFEE BREAK |
| 3:40-4:00 PM | When to consider mid-course changes of therapy based on early response? Gunter von Minckwitz, M.D., Ph.D., German Breast Group Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 4:00-4:20 PM | Follow-up after preoperative therapy, including need for additional systemic therapy Harold J. Burstein, M.D., Ph.D., Dana-Farber Cancer Institute/Harvard Medical School Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 4:20-4:45 PM | Question & Answer for Session III Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
Session IV: Locally advanced and inflammatory breast cancer
Moderators:
Kathy S. Albain, M.D., Loyola University Chicago Stritch School of Medicine
Joseph Sparano, M.D., Albert Einstein Comprehensive Cancer Center
| Time | Title |
|---|---|
| 4:45-5:00 PM | Surgical perspective on locally advanced and inflammatory breast cancers David Byrd, M.D., University of Washington School of Medicine Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 5:00-5:15 PM | Medical oncology perspective on locally advanced breast cancer Stephen Chia, M.D. Vancouver Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 5:15-5:35 PM | Inflammatory breast cancer: A unique pathologic entity? Sandra M. Swain, M.D., Washington Cancer Institute, Washington Hospital Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 5:35-6:00 PM | Question & Answer for Session IV Transcript (pdf) Video for this talk Day 1 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
DAY 2: TUESDAY, MARCH 27, 2007
8:00 am to 4:00 pm
Session V: Local-regional therapy after breast cancer preoperative therapy
Moderators:
Lisa Newman, M.D., MPH, University of Michigan Comprehensive Cancer Center
Timothy Whelan, BM, BCh, MSc, Juravinski Cancer Centre
| Time | Title |
|---|---|
| 8:00 AM | Opening of Day 2 Julie Gralow, M.D., University of Washington School of Medicine Transcript (pdf) Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 8:00-8:20 AM | Indications for radiotherapy and selection of treatment fields after preoperative therapy Thomas Buchholz, M.D., M. D. Anderson Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 8:20-8:40 AM | Surgical issues after preoperative therapy Barbara Pockaj, M.D., Mayo Clinic Arizona Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 8:40-9:00 AM | Reconstruction after preoperative therapy Michael J. Miller, M.D., The Ohio State University Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 9:00-9:25 AM | Question & Answer for Session V Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
Session VI: Preoperative therapy for breast cancer: Research issues
Moderators:
Clifford Hudis, M.D., Memorial Sloan-Kettering Cancer Center
Kathy Pritchard, M.D., Toronto-Sunnybrook Regional Cancer Centre
| Time | Title |
|---|---|
| 9:25-9:45 AM | Importance of obtaining preoperative research biopsies Soonmyung Paik, M.D., NSABP Division of Pathology Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 9:45-10:00 AM | Proliferation and apoptosis as measures of response Mitchell Dowsett, Ph.D., Royal Marsden Hospital, London Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 10:00-10:15 AM | Correlation between chemotherapy response and hormone receptor/HER1/2 expression Marco Colleoni, M.D., European Institute of Oncology Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 10:15-10:30 AM | Molecular profiling Lajos Pusztai, M.D., Ph.D., M. D. Anderson Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 10:30-10:45 AM | COFFEE BREAK |
| 10:45-11:05 AM | PET, MRI, and other imaging David Mankoff, M.D., Ph.D., University of Washington School of Medicine Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 11:05-11:25 AM | "Window of opportunity" studies:
Biologic opportunities and ethical issues
Matthew Ellis, M.B., Ph.D., Washington University in St. Louis School of Medicine Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 11:25-11:45 AM | Statistical considerations in preoperative trials Donald Berry, Ph.D., M. D. Anderson Cancer Center Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 11:45 AM-12:05 PM | Ongoing and planned preoperative trials: Considerations for further research JoAnne Zujewski, M.D., National Cancer Institute Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 12:05-12:20 PM | Role of advocacy in preoperative trials Mary Lou Smith, J.D., M.B.A., Research Advocacy Network Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 12:20-12:50 PM | Question & Answer for Session VI Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
| 12:50-1:50 PM | LUNCH BREAK |
Session VII: Panel Discussion
| Time | Title |
|---|---|
| 1:50-3:20 PM | Panel discussion Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
Moderators:
Gabriel N. Hortobagyi, M.D., F.A.C.P., Chair,
Department of Breast Medical Oncology,
M. D. Anderson Cancer Center
Cokie Roberts, Senior News Analyst,
NPR and ABC News
Panelists:
Harry D. Bear, M.D., Ph.D., Virginia Commonwealth University
Luca Gianni, M.D., Istituto Nazionale Tumori
Daniel F. Hayes, M.D., University of Michigan Comprehensive Cancer Center
Constance D. Lehman, M.D., Ph.D., University of Washington School of Medicine
Soonmyung Paik, M.D., NSABP Division of Pathology
Lori J. Pierce, M.D., University of Michigan Medical School
Andrea Richardson, M.D., Ph.D., Brigham and Women's Hospital
Barbara Smith, M.D., Ph.D., Massachusetts General Hospital
Session VIII: Concluding session
| Time | Title |
|---|---|
| 3:20-4:00 PM | Wrap-up "statement of the science" Julie Gralow, M.D., University of Washington School of Medicine Eric Winer, M.D., Dana-Farber Cancer Institute Presentation slides (pdf) Transcript (pdf) Video for this talk Day 2 audio and podcast RealPlayer, iTunes, and QuickTime (all free) are needed to open video, audio, and podcast, respectively: Free RealPlayer RealPlayer for Mac iTunes QuickTime FAQs about podcasts |
FACULTY LIST:
Speakers, Moderators, and Panelists
Jeffrey Abrams, M.D.
Chief, Clinical Investigations Branch
Cancer Therapy Evaluation Program
Division of Cancer Treatment and Diagnosis
National Cancer Institute
Kathy S. Albain, M.D.
Professor of Medicine
Loyola University Chicago Stritch School of Medicine
Director, Breast Clinical Research Program
Cardinal Bernardin Cancer Center
Harry D. Bear, M.D., Ph.D.
Lawrence Professor of Oncology
Chairman, Division of Surgical Oncology
Virginia Commonwealth University
Massey Cancer Center
Member, NSABP Foundation Board of Directors
Donald Berry, Ph.D.
Chair, Department of Biostatistics & Applied Mathematics
M. D. Anderson Cancer Center
University of Texas
Statistician, Breast Committee, Cancer and Leukemia Group B
Thomas Buchholz, M.D.*, ***
Professor, Radiation Oncology
M. D. Anderson Cancer Center
University of Texas
Harold J. Burstein, M.D., Ph.D.
Instructor, Department of Medicine
Harvard Medical School
Dana-Farber Cancer Institute
Aman Buzdar, M.D.*
Professor of Medicine, Department of Breast Medical Oncology
M. D. Anderson Cancer Center
University of Texas
David Byrd, M.D.
Professor, Department of Surgery
University of Washington School of Medicine
Lisa Carey, M.D.
Medical Director, University of North Carolina-Lineberger Comprehensive Cancer Center
University of North Carolina at Chapel Hill
Stephen Chia, M.D.*
Medical Oncologist
Vancouver Cancer Centre
Marco Colleoni, M.D.
Director, Research Unit in Medical Senology
Department of Medicine
European Institute of Oncology
Nancy Davidson, M.D.
Professor of Oncology
Breast Cancer Research Chair in Oncology
Sidney Kimmel Comprehensive Cancer Center
Joint Appointment in Biochemistry and Molecular Biology
The Johns Hopkins Bloomberg School of Public Health
James Doroshow, M.D.
Director, Division of Cancer Treatment and Diagnosis
National Cancer Institute
Mitchell Dowsett, Ph.D.
Head, Academic Department of Biochemistry
Royal Marsden Hospital, London
Matthew Ellis, M.B., Ph.D.
Associate Professor, Department of Medicine
Oncology Division
Washington University in St. Louis School of Medicine
Vice-Chair, Breast Committee, Cancer and Leukemia Group B
Laura Esserman, M.D., MBA
Professor, Surgery and Radiology
Director, Carol Franc Buck Breast Care Center
UCSF Comprehensive Cancer Center
University of California, San Francisco
Judy E. Garber, M.D., MPH
Director, Cancer Risk and Prevention Program
Associate Professor of Medicine, Harvard Medical School
Dana-Farber Cancer Institute
Luca Gianni, M.D.
Director, Division of Medical Oncology
Head, Clinical Pharmacology Laboratory
Istituto Nazionale Tumori, Milan
Julie Gralow, M.D.**, ***
Associate Professor, Medical Oncology
University of Washington School of Medicine and
Fred Hutchinson Cancer Research Center
Co-Chair, Breast Committee, Southwest Oncology Group
Jay Harris, M.D.
Chair, Department of Radiation Oncology
Dana-Farber Cancer Institute/
Brigham and Women's Hospital
Professor of Radiation Oncology
Harvard Medical School
Daniel F. Hayes, M.D.
Clinical Director, Breast Oncology Program
University of Michigan Comprehensive Cancer Center
Gabriel N. Hortobagyi, M.D., F.A.C.P.
Chair, Department of Breast Medical Oncology
M. D. Anderson Cancer Center
University of Texas
Clifford Hudis, M.D.
Chief, Breast Cancer Medicine Service, Memorial Sloan-Kettering Cancer Center
Co-Chair, Breast Committee, Cancer and Leukemia Group B
Nola Hylton, Ph.D.
Director, Magnetic Resonance Science Center
University of California, San Francisco
Nagi Khouri, M.D.
Director of Breast Imaging
Johns Hopkins University Sidney Kimmel Comprehensive Cancer Center
Constance D. Lehman, M.D., Ph.D.
Associate Professor, Radiology, University of Washington School of Medicine
Director of Breast Imaging, Seattle Cancer Care Alliance
Terry Mamounas, M.D., MPH*, ***
Medical Director
Aultman Cancer Center
Chair, Breast Committee, National Surgical Adjuvant Breast and Bowel Project
David Mankoff, M.D., Ph.D.*, ***
Professor, Radiology Department
University of Washington School of Medicine
Michael J. Miller, M.D.
Professor of Surgery
Chief, Division of Plastic Surgery
The Ohio State University
Lisa Newman, M.D., MPH
Medical Director, Breast Cancer Center
Associate Professor, Surgery
University of Michigan Comprehensive Cancer Center
Larry Norton, M.D.
Deputy Physician-in-Chief for Breast Cancer Programs
Norna S. Sarofim Chair in Clinical Oncology
Memorial Sloan-Kettering Cancer Center
Soonmyung Paik, M.D.
Director, Division of Pathology
National Surgical Adjuvant Breast and Bowel Project
Edith A. Perez, M.D.
Professor of Medicine
Director, Clinical Investigations
Director, Breast Cancer Program
Division of Hematology/Oncology
Mayo Clinic Jacksonville
Chair, Breast Committee, North Central Cancer Treatment Group
Lori J. Pierce, M.D.
Professor, Department of Radiation Oncology
University of Michigan Medical School
Barbara Pockaj, M.D.*
Associate Professor of Surgery
Mayo Clinic Arizona
Kathy Pritchard, M.D.
Professor of Medicine, University of Toronto
Chair, Breast Cancer Site Group, Toronto-Sunnybrook Regional Cancer Centre
Co-Chair, Breast Site Group, National Cancer Institute of Canada Clinical Trials Group
Lajos Pusztai, M.D., Ph.D.
Associate Professor, Breast Medical Oncology
M. D. Anderson Cancer Center
University of Texas
Andrea Richardson M.D. Ph.D.
Instructor, Department of Pathology, Harvard Medical School
Associate Physician, Surgical Pathology, Brigham and Women's Hospital
Cokie Roberts
Senior News Analyst, NPR and ABC News
Baljit Singh, M.B.B.S., M.D.
Associate Professor, Department of Pathology
New York University Medical Center
George W. Sledge, Jr., M.D.
Professor of Medicine, Hematology/Oncology
Indiana University School of Medicine
Chair, Breast Committee, Eastern Cooperative Oncology Group
Barbara L. Smith, M.D., Ph.D.
Surgical Oncologist
Co-Director, Gillette Center for Women’s Cancers
Massachusetts General Hospital
Ian Smith, M.D.
Professor of Cancer Medicine, Department of Medicine
Head of Breast Unit
Royal Marsden Hospital, London
Mary Lou Smith, J.D., M.B.A.
Co-Founder
Research Advocacy Network
Joseph Sparano, M.D.
Professor of Medicine, Albert Einstein College of Medicine
Director, Breast Evaluation Center
Director, Clinical Trials Office
Albert Einstein Comprehensive Cancer Center
Montefiore Medical Center
Vice-Chair, Breast Committee, Eastern Cooperative Oncology Group
Sandra M. Swain, M.D.*
Medical Director
Washington Cancer Institute
Washington Hospital Center
W. Fraser Symmans, M.D.*
Associate Professor of Pathology
M. D. Anderson Cancer Center
University of Texas
Gunter von Minckwitz, M.D., Ph.D.
Board of Directors, Breast International Group
Principal Investigator, German Breast Group
Timothy Whelan, BM, BCh, MSc
Radiation Oncologist
Professor, Department of Medicine, McMaster University
Director, Supportive Cancer Care Research Unit, Juravinski Cancer Centre
Co-Chair, Breast Site Group, National Cancer Institute of Canada Clinical Trials Group
Eric Winer, M.D.**, ***
Director, Breast Oncology Center
Dana-Farber Cancer Institute
Associate Professor of Medicine
Harvard Medical School
Co-Chair, Breast Committee, Cancer and Leukemia Group B
Antonio C. Wolff, M.D.*, ***
Associate Professor of Oncology
Johns Hopkins University
The Sidney Kimmel Comprehensive Cancer Center
Norman Wolmark, M.D.
Chairman, National Surgical Adjuvant Breast and Bowel Project
Professor and Chairman of Human Oncology, Drexel University School of Medicine
Chairman, Department of Human Oncology, Allegheny General Hospital
William Wood, M.D.
Joseph Brown Whitehead Professor and Chairman, Department of Surgery
Emory University School of Medicine
Chair, The Breast Cancer Intergroup of North America
JoAnne Zujewski, M.D. **, ***
Head, Breast Cancer Therapeutics
Clinical Investigations Branch
Cancer Therapy Evaluation Program
Division of Cancer Treatment and Diagnosis
National Cancer Institute
*Planning Committee
**Co-Chair, Planning Committee
*** Writing committee
Also on Planning Committee:
Sandra Batte
Patient Advocate
The Susan G. Komen Foundation
Rose Mary Padberg, R.N., M.A.
Branch Chief, Cancer Education
National Cancer Institute
Rebecca Enos, MPH
NCI Contractor
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