Human Health Consequences of Climate Variability and Change for the United States
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Preface

Joel D. Scheraga
p. 175
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Comments on the Process and Product of the Health Impacts Assessment Component of the National Assessment of the Potential Consequences of Climate Variability and Change for the United States

Susan M. Bernard and Kristie L. Ebi
p. 177
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The Potential Impacts of Climate Variability and Change on Temperature-Related Morbidity and Mortality in the United States

Michael A. McGeehin and Maria Mirabelli
p. 185
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The Potential Impacts of Climate Variability and Change on Health Impacts of Extreme Weather Events in the United States

Gregg Greenough, Michael McGeehin, Susan M. Bernard, Juli Trtanj, Jasmin Riad, and David Engelberg
p. 191
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The Potential Impacts of Climate Variability and Change on Air Pollution-Related Health Effects in the United States

Susan M. Bernard, Jonathan M. Samet, Anne Grambsch, Kristie L. Ebi, and Isabelle Romieu
p. 199
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Climate Variability and Change in the United States: Potential Impacts on Water- and Foodborne Diseases Caused by Microbiologic Agents

Joan B. Rose, Paul R. Epstein, Erin K. Lipp, Benjamin H. Sherman, Susan M. Bernard, and Jonathan A. Patz
p. 211
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Climate Variability and Change in the United States: Potential Impacts on Vector- and Rodent-Borne Diseases

Duane J. Gubler, Paul Reiter, Kristie L. Ebi, Wendy Yap, Roger Nasci, and Jonathan A. Patz
p. 223
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International Conference on the Toxicology of Fumonisin: Introduction

Willam T. Allaben, John R. Bucher, and Paul C. Howard

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Background

Discovery and Occurrence of the Fumonisins: A Historical Perspective

Walter F.O. Marasas
p. 239
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Fumonisin Chemistry

Structure, Synthesis, and Biosynthesis of Fumonisin B₁ and Related Compounds

John W. ApSimon
p. 245
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Comparative Toxicology

Fumonisin Toxicosis in Swine: An Overview of Porcine Pulmonary Edema and Current Perspectives

Wanda M. Haschek, Laura A. Gumprecht, Geoffrey Smith, Mike E. Tumbleson, and Peter D. Constable
p. 251
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An Overview of Rodent Toxicities: Liver and Kidney Effects of Fumonisins and Fusarium moniliforme

Kenneth A. Voss, Ronald T. Riley, W.P. Norred, Charles W. Bacon, Filmore I. Meredith, Paul C. Howard, Ronald D. Plattner, Thomas F.X. Collins, Deborah K. Hansen, and James K. Porter
p. 259
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Toxicity of Culture Material of Fusarium verticillioides Strain MRC 826 to Nonhuman Primates

Wentzel C.A. Gelderblom, Jurgen V. Seier, Petra W. Snijman, Dirk J. Van Schalkwyk, Gordon S. Shephard, and Walter F.O. Marasas
p. 267
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NTP Bioassay and Mechanisms of Carcinogenesis

Fumonisin B₁ Carcinogenicity in a Two-Year Feeding Study Using F344 Rats and B6C3F₁ Mice

Paul C. Howard, Robert M. Eppley, Michael E. Stack, Alan Warbritton, Kenneth A. Voss, Ronald J. Lorentzen, Robert M. Kovach, and Thomas J. Bucci
p. 277
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Sphingolipid Metabolism: Roles in Signal Transduction and Disruption by Fumonisins

Alfred H. Merrill Jr., M. Cameron Sullards, Elaine Wang, Kenneth A. Voss, and Ronald T. Riley
p. 283
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Fumonisin-Induced Hepatocarcinogenesis: Mechanisms Related to Cancer Initiation
and Promotion

Wentzel C.A. Gelderblom, Stefan Abel, Cornelius M. Smuts, Jeanine Marnewick, Walter F.O. Marasas, Eric R. Lemmer, and Danica Ramljak
p. 291
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Sphingolipid Perturbations as Mechanisms for Fumonisin Carcinogenesis

Ronald T. Riley, Evaristus Enongene, Kenneth A. Voss, William P. Norred, Filmore I. Meredith, Raghubir P. Sharma, Jan Spitsbergen, David E. Williams, David B. Carlson, and Alfred H. Merrill Jr.
p. 301
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Compensatory Regeneration as a Mechanism for Renal Tubule Carcinogenesis of Fumonisin B₁ in the F344/N/Nctr BR Rat

Paul C. Howard, Alan Warbritton, Kenneth A. Voss, Ronald J. Lorentzen, J. Dale Thurman, Robert M. Kovach, and Thomas J. Bucci
p. 309
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Analysis of Fumonisin B₁-Induced Apoptosis

Clinton Jones, Janice R. Ciacci-Zanella, Yange Zhang, Gail Henderson, and Martin Dickman
p. 315
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Occurrence and Related Issues

Factors That Affect the Occurrence of Fumonisin

J. David Miller
p. 321
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Biological Control of Fusarium moniliforme in Maize

Charles W. Bacon, Ida E. Yates, Dorothy M. Hinton, and Filmore Meredith
p. 325
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Control of Fumonisin: Effects of Processing

D. Stephen Saunders, Filmore I. Meredith, and Kenneth A. Voss
p. 333
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Prospects for Reducing Fumonisin Contamination of Maize through Genetic Modification

Jon Duvick
p. 337
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