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Animal Studies in LFMI
Work in LFMI often makes use of animal models,
especially rodents. This work is done in a manner that is consistent with all of the rules and regulations
of the NINDS IACUC. Rodents are used for three types of studies:
- Advancing non-invasive assessment of brain function using anatomical, functional, and molecular imaging techniques
- Elucidating the regulation and control of cellular energy metabolism and the role of creatine kinase
- Development of imaging techniques useful for analyzing transgenic mice to help with functional genomic studies
- Understanding control of cerbral microcirculation
- Establishing the marmoset as an animal modal for marmost study of the brain
Active LFMI animal protocols:
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897-99 | Breeding of Mice for Experiments in Laboratory of Functional and Molecular Imaging. | | | |
898-99 | NMR Studies of Organ Function and Metabolism in Transgenic Mice
and Rats. | | | |
983-002 | Imaging Brain Function in Rats and Mice | | | |
988-002 | Generation, Breeding, and analysis of Transgenic Mice | | | |
1160-04 | Imaging Brain Plasticity in Rats and Mice | | | |
1187-04 | Breeding of Marmosets | | | |
1191-05 | Magnetic Resonance Imaging Characterization of the Neuro-architecture and Cerebral Microvasculature in Marmosets | | | |
1209-05 | Investigation of the Cerebrovascular Coupling in Rats and Mice | | |
How to get started?
Work with animals in LFMI is done under
the supervision of the NINDS IACUC and the NIH NMR Center Mouse Imaging Committee. For a detailed
description of procedures that are followed prior to starting any animal studies in LFMI, please go to the
NMRF web site.
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