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Images published by Advanced Magnetic Resonance Imaging Section
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T2*-weighted in-vivo brain scan at 7 T, 20-channel brain array resolution 200x200x1000 micrometer, measurement time 5 minutes

 
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BOLD fMRI of motor cortex at 7 T, 8-channel brain array resolution 1250x1250x1000 micrometer, measurement time 5 minutes

 
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Perfusion-weighted in-vivo brain scan at 7 T, 8-channel brain array resolution 1500x1500x2000 micrometer, measurement time 5 minutes

 
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T1-weighted in-vivo brain scan at 7 T, 8-channel brain array resolution 400x400x1000 micrometer, measurement time 8 minutes

 
Images published by Cerebral Microcirculation Unit Section
Images published by Functional and Molecular Metabolism Section
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Light microscopy images of hepatocytes labeled with (a)0.96-, (b)1.63-, (c)2.79-, (d)4.50-, and (e)5.80-&$181m particles. Cark perinuclear spheres are individual MPIOs. Partcle numbers per cell ranged from several hundred for the smaller particles to tens for the largest particles. d and e: Thirty -five 4.5-&$181m and 17 5.8-&$181m particles, yielding iron contents of ~387 and 75 pg iron, respectively.
Erik M. Shapiro, Sizing It Up: Cellular MRI Using Micron-Sized Iron Oxide Particles, Magnetic Resonance in Medicine 53:329-338(2005)

 
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Single 4.5-�m MPIO GRE-MR image. a:Imaging Parameter are given as resolution/TE for each image. B:Average profile plots for three different image resolutions.
Erik M. Shapiro, Sizing It Up: Cellular MRI Using Micron-Sized Iron Oxide Particles, Magnetic Resonance in Medicine 53:329-338(2005)

 
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Averaged BOLD time courses obtained at 40-ms temporal resolution from all nine animals used in this study. Layers IV-V present the fastest onset time to stimulation, followed by layers I-III and VI. Vertical bars = 1 standard error. The inset clearly shows the difference in onset times (error bars omitted for clarity).
Afonso C. Silva, Laminar Specficity of Functional MRI Onset Times During Somatosensory Stimulation in Rat, PNAS Vol. 99 no.23 15182-15287(2002)

 
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Typical gradient-echo coronal MR images of a rat brain obtained at 11.7T. Spatial resolution is 50 X 50 X 2,000 �m2. Overlaid on top of the images are functional maps generated during electrical stimulation of the left forepaw. (A)Cross-correlation map shows the temporal resemblance of each pixel time course to the functional paradigm. The color bar indicates the scale of CCCs. Pixels that best resemble the functional paradigm are located in the middle layers (IV-V) of the somatosensory cortex. (B)Percent change map shows the intensity of BOLD relative signal changes. The color bar indicates the range of signal changes. The highest signal changes are located along the pial surface, corresponding to the extravascular component associated with large vessels.
Afonso C. Silva, Laminar Specficity of Functional MRI Onset Times During Somatosensory Stimulation in Rat, PNAS Vol. 99 no.23 15182-15287(2002)

 
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MRI images of the olfactory bulb of a mouse exposed to Mn2+ only (left) and Mn2+ plus amyl acetate (right). MEMRI images of the mouse were obtained 1.5h after exposure to aerosolized Mn2+ alone or in the presence of mnyl acetate. The localized accumulation of Mn2+ is seen as positive contrast enhancement in the olfactory bulb.
Robia G. Pautler, Tracing Odor-Induced Activation in the Olfactory bulbs of Mice Using Manganese-Enhanced Magnetic Resonance Imaging, NeuroImage 16,441-448(2002)

 
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Accessory olfactory bulb enhancement by MEMRI after exposure to phermones and Mn2+. Areas enhanced are readily detected as bright regions in axial (left) as well as sagittal (right) slices. The arrowheads point to the bilaterally symmetric accessory olfactory bulb, which appears as bright circles in the axial slice and is located caudal in the olfactory bulband rostral to the main cortical areas in the saggital slice.
Robia G. Pautler, Tracing Odor-Induced Activation in the Olfactory bulbs of Mice Using Manganese-Enhanced Magnetic Resonance Imaging, NeuroImage 16,441-448(2002)

 
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T1-weighted MRI(350X350X600 �m3 spatial resolution) in the visual cortex, acquired at 3 T. The white arrows point to a thin white line, which we identify as the stripe of Gennari. The insert image (SPGR with inversion pre-pulse: TI = 400 ms, TR = 13ms, TE = 6ms, flip angle = 19�, FOV = 20X20mm2, slice thickness = 1.2mm, matrix size = 256 X 256).
Emmanuel L. Barbier, Imaging Cortical Anatomy by High-Resolution MR at 3.0T: Detection of the Stripe of Gennari in Visual Area 17, Magnetic Resonance in Medicine 48:735-738(2002)

 

 
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