| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 September 13; 102(37): 12999–13000. doi: 10.1073/iti3705102.PMCID: PMC1201631 Commentary Two ways to trap a gene in mice William C. Skarnes PMCID: PMC1201614 Perspective Transgenes in Mexican maize: Desirability or inevitability? Peter H. Raven PMCID: PMC1201607 Physical Sciences Chemistry RNA–protein recognition: Single-residue ultrafast dynamical control of structural specificity and function Tianbing Xia, Chaozhi Wan, Richard W. Roberts, and Ahmed H. Zewail PMCID: PMC1201610 Hydrogen bonds in liquid water are broken only fleetingly J. D. Eaves, J. J. Loparo, C. J. Fecko, S. T. Roberts, A. Tokmakoff, and P. L. Geissler PMCID: PMC1201598 Marine phosphate oxygen isotopes and organic matter remineralization in the oceans Albert S. Colman, Ruth E. Blake, David M. Karl, Marilyn L. Fogel, and Karl K. Turekian PMCID: PMC1201620 Physics Structure of stochastic dynamics near fixed points Chulan Kwon, Ping Ao, and David J. Thouless PMCID: PMC1201617 Biological Sciences Anthropology Ancient mitochondrial M haplogroups identified in the Southwest Pacific D. Andrew Merriwether, Jason A. Hodgson, Françoise R. Friedlaender, Robin Allaby, Salvatore Cerchio, George Koki, and Jonathan S. Friedlaender PMCID: PMC1201611 Applied Biological Sciences Solid tumor risks after high doses of ionizing radiation Rainer K. Sachs and David J. Brenner PMCID: PMC1199000 Biochemistry Crystal structure of dihydrofolate reductase from Plasmodium vivax: Pyrimethamine displacement linked with mutation-induced resistance Palangpon Kongsaeree, Puttapol Khongsuk, Ubolsree Leartsakulpanich, Penchit Chitnumsub, Bongkoch Tarnchompoo, Malcolm D. Walkinshaw, and Yongyuth Yuthavong PMCID: PMC1201571 Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch Stephanie A. Lee, Rosemary Eyeson, Matthew L. Cheever, Jinming Geng, Vladislav V. Verkhusha, Christopher Burd, Michael Overduin, and Tatiana G. Kutateladze PMCID: PMC1201587 Crystal structure of human arginase I at 1.29-Å resolution and exploration of inhibition in the immune response Luigi Di Costanzo, Guadalupe Sabio, Alfonso Mora, Paulo C. Rodriguez, Augusto C. Ochoa, Francisco Centeno, and David W. Christianson PMCID: PMC1201588 Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP Stephen P. L. Cary, Jonathan A. Winger, and Michael A. Marletta PMCID: PMC1201615 Structure and mechanism of the reversible photoswitch of a fluorescent protein Martin Andresen, Markus C. Wahl, André C. Stiel, Frauke Gräter, Lars V. Schäfer, Simon Trowitzsch, Gert Weber, Christian Eggeling, Helmut Grubmüller, Stefan W. Hell, and Stefan Jakobs PMCID: PMC1201575 Identification of a peptide fragment of DSCR1 that competitively inhibits calcineurin activity in vitro and in vivo Betty Chan, Garrett Greenan, Frank McKeon, and Tom Ellenberger PMCID: PMC1201586 Biophysics RNA–protein recognition: Single-residue ultrafast dynamical control of structural specificity and function Tianbing Xia, Chaozhi Wan, Richard W. Roberts, and Ahmed H. Zewail PMCID: PMC1201610 Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution Mats G. L. Gustafsson PMCID: PMC1201569 Initial electron donor and acceptor in isolated Photosystem II reaction centers identified with femtosecond mid-IR spectroscopy Marie Louise Groot, Natalia P. Pawlowicz, Luuk J. G. W. van Wilderen, Jacques Breton, Ivo H. M. van Stokkum, and Rienk van Grondelle PMCID: PMC1196200 Crystal structure of the GTPase domain of rat dynamin 1 Thomas F. Reubold, Susanne Eschenburg, Andreas Becker, Marilyn Leonard, Sandra L. Schmid, Richard B. Vallee, F. Jon Kull, and Dietmar J. Manstein PMCID: PMC1201622 Statistical coil model of the unfolded state: Resolving the reconciliation problem Abhishek K. Jha, Andrés Colubri, Karl F. Freed, and Tobin R. Sosnick PMCID: PMC1201606 The crystal structure of a cross-linked actin dimer suggests a detailed molecular interface in F-actin Dmitry S. Kudryashov, Michael R. Sawaya, Helty Adisetiyo, Todd Norcross, György Hegyi, Emil Reisler, and Todd O. Yeates PMCID: PMC1196358 Allostery of actin filaments: Molecular dynamics simulations and coarse-grained analysis Jhih-Wei Chu and Gregory A. Voth PMCID: PMC1201585 Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Kai-Fa Huang, Yi-Liang Liu, Wei-Ju Cheng, Tzu-Ping Ko, and Andrew H.-J. Wang PMCID: PMC1201592 Cell Biology Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model Mirka Uhlirova, Heinrich Jasper, and Dirk Bohmann PMCID: PMC1201591 From the Cover:
Transcriptional regulation of phagocytosis-induced membrane biogenesis by sterol regulatory element binding proteins Adam B. Castoreno, Yan Wang, Walter Stockinger, Larissa A. Jarzylo, Hong Du, Joanne C. Pagnon, Eugenie C. Shieh, and Axel Nohturfft PMCID: PMC1201629 Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation Atsushi Iwata, John C. Christianson, Mirella Bucci, Lisa M. Ellerby, Nobuyuki Nukina, Lysia S. Forno, and Ron R. Kopito PMCID: PMC1201602 Thrombospondin-1 inhibits endothelial cell responses to nitric oxide in a cGMP-dependent manner Jeff S. Isenberg, Lisa A. Ridnour, Elizabeth M. Perruccio, Michael G. Espey, David A. Wink, and David D. Roberts PMCID: PMC1201579 Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1 Lisa A. Ridnour, Jeffrey S. Isenberg, Michael G. Espey, Douglas D. Thomas, David D. Roberts, and David A. Wink PMCID: PMC1201580 Estrogen down-regulation of the corepressor N-CoR: Mechanism and implications for estrogen derepression of N-CoR-regulated genes Jonna Frasor, Jeanne M. Danes, Cory C. Funk, and Benita S. Katzenellenbogen PMCID: PMC1201577 MgcRacGAP controls the assembly of the contractile ring and the initiation of cytokinesis Wei-meng Zhao and Guowei Fang PMCID: PMC1201590 Caspase-mediated degradation of human 5-lipoxygenase in B lymphocytic cells Oliver Werz, Irina Tretiakova, Angela Michel, Annegret Ulke-Lemee, Michael Hörnig, Lutz Franke, Gisbert Schneider, Bengt Samuelsson, Olof Rådmark, and Dieter Steinhilber PMCID: PMC1201604 Developmental Biology Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation Valerie Kouskoff, Georges Lacaud, Staci Schwantz, Hans Jöerg Fehling, and Gordon Keller PMCID: PMC1201570 Bicoid cooperative DNA binding is critical for embryonic patterning in Drosophila Danielle Lebrecht, Marisa Foehr, Eric Smith, Francisco J. P. Lopes, Carlos E. Vanario-Alonso, John Reinitz, David S. Burz, and Steven D. Hanes PMCID: PMC1201621 Environmental Sciences Marine phosphate oxygen isotopes and organic matter remineralization in the oceans Albert S. Colman, Ruth E. Blake, David M. Karl, Marilyn L. Fogel, and Karl K. Turekian PMCID: PMC1201620 Genetics A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM Yingli Sun, Xiaofeng Jiang, Shujuan Chen, Norvin Fernandes, and Brendan D. Price PMCID: PMC1197271 From the Cover:
Gene targeting using a promoterless gene trap vector (“targeted trapping”) is an efficient method to mutate a large fraction of genes Roland H. Friedel, Andrew Plump, Xiaowei Lu, Kerri Spilker, Christine Jolicoeur, Karen Wong, Tadmiri R. Venkatesh, Avraham Yaron, Mary Hynes, Bin Chen, Ami Okada, Susan K. McConnell, Helen Rayburn, and Marc Tessier-Lavigne PMCID: PMC1193537 A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility Jennifer L. Shepard, James F. Amatruda, Howard M. Stern, Aravind Subramanian, David Finkelstein, James Ziai, K. Rose Finley, Kathleen L. Pfaff, Candace Hersey, Yi Zhou, Bruce Barut, Matthew Freedman, Charles Lee, Jan Spitsbergen, Donna Neuberg, Gerhard Weber, Todd R. Golub, Jonathan N. Glickman, Jeffery L. Kutok, Jon C. Aster, and Leonard I. Zon PMCID: PMC1198999 Deletion of XPC leads to lung tumors in mice and is associated with early events in human lung carcinogenesis M. Christine Hollander, Robyn T. Philburn, Andrew D. Patterson, Susana Velasco-Miguel, Errol C. Friedberg, R. Ilona Linnoila, and Albert J. Fornace, Jr. PMCID: PMC1201581 Comparative physical mapping links conservation of microsynteny to chromosome structure and recombination in grasses John E. Bowers, Miguel A. Arias, Rochelle Asher, Jennifer A. Avise, Robert T. Ball, Gene A. Brewer, Ryan W. Buss, Amy H. Chen, Thomas M. Edwards, James C. Estill, Heather E. Exum, Valorie H. Goff, Kristen L. Herrick, Cassie L. James Steele, Santhosh Karunakaran, Gmerice K. Lafayette, Cornelia Lemke, Barry S. Marler, Shelley L. Masters, Joana M. McMillan, Lisa K. Nelson, Graham A. Newsome, Chike C. Nwakanma, Rosana N. Odeh, Cynthia A. Phelps, Elizabeth A. Rarick, Carl J. Rogers, Sean P. Ryan, Keimun A. Slaughter, Carol A. Soderlund, Haibao Tang, Rod A. Wing, and Andrew H. Paterson PMCID: PMC1201573 A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells Frank Stegmeier, Guang Hu, Richard J. Rickles, Gregory J. Hannon, and Stephen J. Elledge PMCID: PMC1196357 Immunology From the Cover:
Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway Timothy C. Cheung, Ian R. Humphreys, Karen G. Potter, Paula S. Norris, Heather M. Shumway, Bonnie R. Tran, Ginelle Patterson, Rochelle Jean-Jacques, Miri Yoon, Patricia G. Spear, Kenneth M. Murphy, Nell S. Lurain, Chris A. Benedict, and Carl F. Ware PMCID: PMC1201609 Recognition of peptide–MHC class I complexes by activating killer immunoglobulin-like receptors C. Andrew Stewart, Fanny Laugier-Anfossi, Frédéric Vély, Xavier Saulquin, Jenifer Riedmuller, Agnès Tisserant, Laurent Gauthier, François Romagné, Géraldine Ferracci, Fernando A. Arosa, Alessandro Moretta, Peter D. Sun, Sophie Ugolini, and Eric Vivier PMCID: PMC1201584 Requirements for induction and maintenance of peripheral tolerance in stringent allograft models Masayuki Sho, Koji Kishimoto, Hiroshi Harada, Mauren Livak, Alberto Sanchez-Fueyo, Akira Yamada, Xin Xiao Zheng, Terry B. Strom, Giacomo P. Basadonna, Mohamed H. Sayegh, and David M. Rothstein PMCID: PMC1201597 Knockdown of Pu.1 by small interfering RNA in CD34+ embryoid body cells derived from mouse ES cells turns cell fate determination to pro-B cells Gang-Ming Zou, Jian-Jun Chen, Mervin C. Yoder, Wei Wu, and Janet D. Rowley PMCID: PMC1201612 Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination James S. Rush, Man Liu, Valerie H. Odegard, Shyam Unniraman, and David G. Schatz PMCID: PMC1201576 The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells Geanncarlo Lugo-Villarino, Shu-Ichi Ito, Dennis M. Klinman, and Laurie H. Glimcher PMCID: PMC1201626 Medical Sciences From the Cover:
Microbial regulation of intestinal radiosensitivity Peter A. Crawford and Jeffrey I. Gordon PMCID: PMC1193536 Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the –174 IL-6 G/C polymorphism in children Andrew Sawczenko, Omeia Azooz, Joanna Paraszczuk, Maja Idestrom, Nick M. Croft, Martin O. Savage, Anne B. Ballinger, and Ian R. Sanderson PMCID: PMC1198995 Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells Niklas Feldhahn, Paula Río, Bonaventure Ndikung Bejeng Soh, Stefanie Liedtke, Mieke Sprangers, Florian Klein, Peter Wernet, Hassan Jumaa, Wolf-Karsten Hofmann, Helmut Hanenberg, Janet D. Rowley, and Markus Müschen PMCID: PMC1201599 Microbiology Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection Makoto Kuroda, Atsushi Yamashita, Hideki Hirakawa, Miyuki Kumano, Kazuya Morikawa, Masato Higashide, Atsushi Maruyama, Yumiko Inose, Kimio Matoba, Hidehiro Toh, Satoru Kuhara, Masahira Hattori, and Toshiko Ohta PMCID: PMC1201578 Receptor-specific requirements for anthrax toxin delivery into cells G. Jonah A. Rainey, Darran J. Wigelsworth, Patricia L. Ryan, Heather M. Scobie, R. John Collier, and John A. T. Young PMCID: PMC1201603 Neuroscience Nonpharmacological amelioration of age-related learning deficits: The impact of hippocampal θ-triggered training Yukiko Asaka, Kristin N. Mauldin, Amy L. Griffin, Matthew A. Seager, Elizabeth Shurell, and Stephen D. Berry PMCID: PMC1201623 Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila Qi Wu, Yan Zhang, Jie Xu, and Ping Shen PMCID: PMC1201572 Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus Tengis Gloveli, Tamar Dugladze, Horacio G. Rotstein, Roger D. Traub, Hannah Monyer, Uwe Heinemann, Miles A. Whittington, and Nancy J. Kopell PMCID: PMC1201613 Regulation of synaptic plasticity in a schizophrenia model Barbara Gisabella, Vadim Y. Bolshakov, and Francine M. Benes PMCID: PMC1201605 Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome Paul S. A. Kalanithi, Wei Zheng, Yuko Kataoka, Marian DiFiglia, Heidi Grantz, Clifford B. Saper, Michael L. Schwartz, James F. Leckman, and Flora M. Vaccarino PMCID: PMC1201574 Electrical synapses in retinal ON cone bipolar cells: Subtype-specific expression of connexins Yi Han and Stephen C. Massey PMCID: PMC1201596 From the Cover:
Neural circuitry underlying the interaction between emotion and asthma symptom exacerbation Melissa A. Rosenkranz, William W. Busse, Tom Johnstone, Cheri A. Swenson, Gina M. Crisafi, Maryjo M. Jackson, Jos A. Bosch, John F. Sheridan, and Richard J. Davidson PMCID: PMC1197272 Fine functional organization of auditory cortex revealed by Fourier optical imaging Valery A. Kalatsky, Daniel B. Polley, Michael M. Merzenich, Christoph E. Schreiner, and Michael P. Stryker PMCID: PMC1201601 Physiology Role of PDZK1 in membrane expression of renal brush border ion exchangers R. Brent Thomson, Tong Wang, Benjamin R. Thomson, Luis Tarrats, Adriana Girardi, SueAnn Mentone, Manoocher Soleimani, Olivier Kocher, and Peter S. Aronson PMCID: PMC1201624 Plant Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: RBR3, a member of the retinoblastoma-related family from maize, is regulated by the RBR1/E2F pathway Paolo A. Sabelli, Ricardo A. Dante, João T. Leiva-Neto, Rudolf Jung, William J. Gordon-Kamm, and Brian A. Larkins PMCID: PMC1201608 Blue light-regulated molecular switch of Ser/Thr kinase in phototropin Daisuke Matsuoka and Satoru Tokutomi PMCID: PMC1198998 Population Biology A model of antibiotic-resistant bacterial epidemics in hospitals Glenn F. Webb, Erika M. C. D'Agata, Pierre Magal, and Shigui Ruan PMCID: PMC1201589 Corrections Proc Natl Acad Sci U S A. 2005 September 13; 102(37): 13349–13350. Published online 2005 September 1. doi: 10.1073/pnas.0506656102.PMCID: PMC1201627 Corrects: Zhiquan Zhang, et al. Assembly of the bacteriophage T4 primosome: Single-molecule and ensemble studies. Proc Natl Acad Sci U S A. 2005 March 1; 102(9): 3254–3259. Proc Natl Acad Sci U S A. 2005 September 13; 102(37): 13351. Published online 2005 August 31. doi: 10.1073/pnas.0506705102.PMCID: PMC1201628 Corrects: Jose H. Hodak, et al. Docking kinetics and equilibrium of a GAAA tetraloop-receptor motif probed by single-molecule FRET. Proc Natl Acad Sci U S A. 2005 July 26; 102(30): 10505–10510. Proc Natl Acad Sci U S A. 2005 September 13; 102(37): 13351. Published online 2005 September 1. doi: 10.1073/pnas.0507060102.PMCID: PMC1201630 Corrects: D. S. Roberts, et al. Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABAA receptor α4 subunit expression. Proc Natl Acad Sci U S A. 2005 August 16; 102(33): 11894–11899. |
