| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 September 6; 102(36): 12647–12648. doi: 10.1073/iti3605102.PMCID: PMC1200318 Commentaries Back to the fold: T cell recognition of HFE, a MHC class Ib molecule that regulates iron metabolism Jonathan W. Yewdell and Heather D. Hickman-Miller PMCID: PMC1200294 Saving islets from allograft rejection Terry B. Strom PMCID: PMC1200297 Physical Sciences Applied Physical Sciences Amorphous layer around aragonite platelets in nacre Nadine Nassif, Nicola Pinna, Nicole Gehrke, Markus Antonietti, Christian Jäger, and Helmut Cölfen PMCID: PMC1200266 Chemistry Toward the development of peptide nanofilaments and nanoropes as smart materials Daniel E. Wagner, Charles L. Phillips, Wasif M. Ali, Grant E. Nybakken, Emily D. Crawford, Alexander D. Schwab, Walter F. Smith, and Robert Fairman PMCID: PMC1193539 Condensed complexes in vesicles containing cholesterol and phospholipids Arun Radhakrishnan and Harden McConnell PMCID: PMC1200296 Asymmetry in angular rigidity of hydrogen-bonded complexes Zhenhong Yu and William Klemperer PMCID: PMC1200308 Mathematics The adjunction problem over torsion-free groups Max Forester and Colin Rourke PMCID: PMC1200269 Biological Sciences Applied Biological Sciences Amorphous layer around aragonite platelets in nacre Nadine Nassif, Nicola Pinna, Nicole Gehrke, Markus Antonietti, Christian Jäger, and Helmut Cölfen PMCID: PMC1200266 Protein “fingerprinting” in complex mixtures with peptoid microarrays M. Muralidhar Reddy and Thomas Kodadek PMCID: PMC1200257 Tuning genetic control through promoter engineering Hal Alper, Curt Fischer, Elke Nevoigt, and Gregory Stephanopoulos PMCID: PMC1200280 Biochemistry Three-dimensional structure of human monoamine oxidase A (MAO A): Relation to the structures of rat MAO A and human MAO B Luigi De Colibus, Min Li, Claudia Binda, Ariel Lustig, Dale E. Edmondson, and Andrea Mattevi PMCID: PMC1200291 Kernel energy method: Application to insulin Lulu Huang, Lou Massa, and Jerome Karle PMCID: PMC1200310 A loop 2 cytidine-stem 1 minor groove interaction as a positive determinant for pseudoknot-stimulated –1 ribosomal frameshifting Peter V. Cornish, Mirko Hennig, and David P. Giedroc PMCID: PMC1200304 Deubiquitinating function of ataxin-3: Insights from the solution structure of the Josephin domain Yuxin Mao, Francesca Senic-Matuglia, Pier Paolo Di Fiore, Simona Polo, Michael E. Hodsdon, and Pietro De Camilli PMCID: PMC1188261 A third Na+-binding site in the sodium pump Ciming Li, Oihana Capendeguy, Käthi Geering, and Jean-Daniel Horisberger PMCID: PMC1200292 Biophysics Condensed complexes in vesicles containing cholesterol and phospholipids Arun Radhakrishnan and Harden McConnell PMCID: PMC1200296 Crystal structures and mutational analysis of amFP486, a cyan fluorescent protein from Anemonia majano J. Nathan Henderson and S. James Remington PMCID: PMC1200261 Structure of the light chain-binding domain of myosin V Mohammed Terrak, Grzegorz Rebowski, Renne C. Lu, Zenon Grabarek, and Roberto Dominguez PMCID: PMC1200277 Specificity versus stability in computational protein design Daniel N. Bolon, Robert A. Grant, Tania A. Baker, and Robert T. Sauer PMCID: PMC1200299 Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition Leo C. James and Dan S. Tawfik PMCID: PMC1200256 Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket Tao Bai, Michael Becker, Aditi Gupta, Phillip Strike, Vince J. Murphy, Robin F. Anders, and Adrian H. Batchelor PMCID: PMC1200259 Physics and evolution of thermophilic adaptation Igor N. Berezovsky and Eugene I. Shakhnovich PMCID: PMC1189736 From the Cover:
Direct NMR observation of a substrate protein bound to the chaperonin GroEL Reto Horst, Eric B. Bertelsen, Jocelyne Fiaux, Gerhard Wider, Arthur L. Horwich, and Kurt Wüthrich PMCID: PMC1188259 Cell Biology From the Cover:
Gliding ghosts of Mycoplasma mobile Atsuko Uenoyama and Makoto Miyata PMCID: PMC1192825 Biological function of the vaccinia virus Z-DNA-binding protein E3L: Gene transactivation and antiapoptotic activity in HeLa cells Jin-Ah Kwon and Alexander Rich PMCID: PMC1200295 Inhibition of Single Minded 2 gene expression mediates tumor-selective apoptosis and differentiation in human colon cancer cells Mireille J. Aleman, Maurice Phil DeYoung, Matthew Tress, Patricia Keating, Gary W. Perry, and Ramaswamy Narayanan PMCID: PMC1200285 Effects of the tumor inhibitory triterpenoid avicin G on cell integrity, cytokinesis, and protein ubiquitination in fission yeast Jordan U. Gutterman, Hong T. Lai, Peirong Yang, Valsala Haridas, Amos Gaikwad, and Stevan Marcus PMCID: PMC1200287 Membrane metabolism mediated by Sec14 family members influences Arf GTPase activating protein activity for transport from the trans-Golgi Tania A. Wong, Gregory D. Fairn, Pak P. Poon, Maya Shmulevitz, Christopher R. McMaster, Richard A. Singer, and Gerald C. Johnston PMCID: PMC1200303 Inositol polyphosphate multikinase is a nuclear PI3-kinase with transcriptional regulatory activity Adam C. Resnick, Adele M. Snowman, Bingnan N. Kang, K. Joseph Hurt, Solomon H. Snyder, and Adolfo Saiardi PMCID: PMC1200306 Curing of yeast [PSI+] prion by guanidine inactivation of Hsp104 does not require cell division Yue-Xuan Wu, Lois E. Greene, Daniel C. Masison, and Evan Eisenberg PMCID: PMC1192827 Evolution Variation in resistance to parasitism in aphids is due to symbionts not host genotype Kerry M. Oliver, Nancy A. Moran, and Martha S. Hunter PMCID: PMC1200300 Domestication of a Mesoamerican cultivated fruit tree, Spondias purpurea Allison Miller and Barbara Schaal PMCID: PMC1200284 Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster Michael R. Bogwitz, Henry Chung, Lorin Magoc, Sheena Rigby, Wayn Wong, Melanie O'Keefe, John A. McKenzie, Philip Batterham, and Phillip J. Daborn PMCID: PMC1200273 Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing Daehyun Baek and Phil Green PMCID: PMC1192826 Evolution of human-chimpanzee differences in malaria susceptibility: Relationship to human genetic loss of N-glycolylneuraminic acid Maria J. Martin, Julian C. Rayner, Pascal Gagneux, John W. Barnwell, and Ajit Varki PMCID: PMC1200275 Genetics Primary sequence independence for prion formation Eric D. Ross, Herman K. Edskes, Michael J. Terry, and Reed B. Wickner PMCID: PMC1200301 A Drosophila DEG/ENaC channel subunit is required for male response to female pheromones Heping Lin, Kevin J. Mann, Elena Starostina, Ronald D. Kinser, and Claudio W. Pikielny PMCID: PMC1200314 Significance analysis of time course microarray experiments John D. Storey, Wenzhong Xiao, Jeffrey T. Leek, Ronald G. Tompkins, and Ronald W. Davis PMCID: PMC1201697 Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6 Michelle Carter, Xu Chen, Bozena Slowinska, Sharon Minnerath, Sara Glickstein, Lei Shi, Fabien Campagne, Harel Weinstein, and M. Elizabeth Ross PMCID: PMC1200260 Clusters of mutations from transient hypermutability John W. Drake, Anna Bebenek, Grace E. Kissling, and Shyamal Peddada PMCID: PMC1200270 Immunology From the Cover:
Direct recognition by αβ cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function Pierre S. Rohrlich, Nicolas Fazilleau, Florent Ginhoux, Hüseyin Firat, Frédérique Michel, Madeleine Cochet, Nihay Laham, Marie Paule Roth, Steve Pascolo, Faridabano Nato, Hélène Coppin, Pierre Charneau, Olivier Danos, Oreste Acuto, Rachel Ehrlich, Jean Kanellopoulos, and François A. Lemonnier PMCID: PMC1200262 CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function Helga Schneider, Elke Valk, Silvy da Rocha Dias, Bin Wei, and Christopher E. Rudd PMCID: PMC1192824 Glucose transporter 1 expression identifies a population of cycling CD4+CD8+ human thymocytes with high CXCR4-induced chemotaxis Louise Swainson, Sandrina Kinet, Nicolas Manel, Jean-Luc Battini, Marc Sitbon, and Naomi Taylor PMCID: PMC1200272 Medical Sciences Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes Julia I. Toth, Shao H. Yang, Xin Qiao, Anne P. Beigneux, Michael H. Gelb, Casey L. Moulson, Jeffrey H. Miner, Stephen G. Young, and Loren G. Fong PMCID: PMC1193538 Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome Brian C. Capell, Michael R. Erdos, James P. Madigan, James J. Fiordalisi, Renee Varga, Karen N. Conneely, Leslie B. Gordon, Channing J. Der, Adrienne D. Cox, and Francis S. Collins PMCID: PMC1200293 Constitutive NF-κB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice Priti Chugh, Hittu Matta, Sandra Schamus, Sunny Zachariah, Arvind Kumar, James A. Richardson, Alice L. Smith, and Preet M. Chaudhary PMCID: PMC1200255 From the Cover:
Cloning of a human parvovirus by molecular screening of respiratory tract samples Tobias Allander, Martti T. Tammi, Margareta Eriksson, Annelie Bjerkner, Annika Tiveljung-Lindell, and Björn Andersson PMCID: PMC1200281 The erythrocyte viral trap: Transgenic expression of viral receptor on erythrocytes attenuates coxsackievirus B infection Damon R. Asher, Anna M. Cerny, and Robert W. Finberg PMCID: PMC1200307 Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection Elisabetta Bianchi, Marco Finotto, Paolo Ingallinella, Renee Hrin, Anthony V. Carella, Xiaoli S. Hou, William A. Schleif, Michael D. Miller, Romas Geleziunas, and Antonello Pessi PMCID: PMC1200264 Microbiology Replication of Yersinia pestis in interferon γ-activated macrophages requires ripA, a gene encoded in the pigmentation locus Céline Pujol, Jens P. Grabenstein, Robert D. Perry, and James B. Bliska PMCID: PMC1200267 Role of specific hemagglutinin amino acids in the immunogenicity and protection of H5N1 influenza virus vaccines Erich Hoffmann, Aleksandr S. Lipatov, Richard J. Webby, Elena A. Govorkova, and Robert G. Webster PMCID: PMC1200312 Interferon function is not required for recovery from a secondary poxvirus infection Vijay Panchanathan, Geeta Chaudhri, and Gunasegaran Karupiah PMCID: PMC1200282 Listeria monocytogenes phosphatidylinositol-specific phospholipase C has evolved for virulence by greatly reduced activity on GPI anchors Zhengyu Wei, Lauren A. Zenewicz, and Howard Goldfine PMCID: PMC1200258 A transcriptional response to replication status mediated by the conserved bacterial replication protein DnaA Alexi I. Goranov, Luba Katz, Adam M. Breier, Christopher B. Burge, and Alan D. Grossman PMCID: PMC1200305 Neuroscience Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene Jeffrey S. Mogil, Frank Miermeister, Frank Seifert, Kate Strasburg, Katharina Zimmermann, Heiko Reinold, Jean-Sebastien Austin, Nadia Bernardini, Elissa J. Chesler, Heiko A. Hofmann, Christian Hordo, Karl Messlinger, Kumar V. S. Nemmani, Andrew L. Rankin, Jennifer Ritchie, Angela Siegling, Shad B. Smith, Susana Sotocinal, Axel Vater, Sonya G. Lehto, Sven Klussmann, Remi Quirion, Martin Michaelis, Marshall Devor, and Peter W. Reeh PMCID: PMC1200271 From the Cover:
An isoform-specific allele of Drosophila N-cadherin disrupts a late step of R7 targeting Aljoscha Nern, Louis-Vu T. Nguyen, Tory Herman, Saurabh Prakash, Thomas R. Clandinin, and S. Lawrence Zipursky PMCID: PMC1192823 The subjective experience of pain: Where expectations become reality Tetsuo Koyama, John G. McHaffie, Paul J. Laurienti, and Robert C. Coghill PMCID: PMC1200254 Central IL-1 receptor signaling regulates bone growth and mass Alon Bajayo, Inbal Goshen, Sharon Feldman, Valer Csernus, Kerstin Iverfeldt, Esther Shohami, Raz Yirmiya, and Itai Bab PMCID: PMC1200265 Pharmacology Tumor-specific targeting of an anticancer drug delivery system by LHRH peptide S. S. Dharap, Y. Wang, P. Chandna, J. J. Khandare, B. Qiu, S. Gunaseelan, P. J. Sinko, S. Stein, A. Farmanfarmaian, and T. Minko PMCID: PMC1200279 Plant Biology Anatomical and photosynthetic acclimation to the light environment in species with differing mechanisms of phloem loading Véronique Amiard, Kristine E. Mueh, Barbara Demmig-Adams, Volker Ebbert, Robert Turgeon, and William W. Adams, III PMCID: PMC1200274 The plant cell wall matrix harbors a precursor of defense signaling peptides Javier Narváez-Vásquez, Gregory Pearce, and Clarence A. Ryan PMCID: PMC1200283 Arabidopsis TCP20 links regulation of growth and cell division control pathways Chengxia Li, Thomas Potuschak, Adán Colón-Carmona, Rodrigo A. Gutiérrez, and Peter Doerner PMCID: PMC1200278 DICER-LIKE 4 functions in trans-acting small interfering RNA biogenesis and vegetative phase change in Arabidopsis thaliana Zhixin Xie, Edwards Allen, April Wilken, and James C. Carrington PMCID: PMC1200315 Flagellin induces innate immunity in nonhost interactions that is suppressed by Pseudomonas syringae effectors Xinyan Li, Huiqiong Lin, Weiguo Zhang, Yan Zou, Jie Zhang, Xiaoyan Tang, and Jian-Min Zhou PMCID: PMC1200263 Corrections Proc Natl Acad Sci U S A. 2005 September 6; 102(36): 12996. doi: 10.1073/pnas.0506417102.PMCID: PMC1200313 Corrects: Jue Lin, et al. From the Cover:
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein. Proc Natl Acad Sci U S A. 2004 October 12; 101(41): 14713–14718. Proc Natl Acad Sci U S A. 2005 September 6; 102(36): 12997. doi: 10.1073/pnas.0506509102.PMCID: PMC1200316 Corrects: Mohammed Akbar, et al. Docosahexaenoic acid: A positive modulator of Akt signaling in neuronal survival. Proc Natl Acad Sci U S A. 2005 August 2; 102(31): 10858–10863. Proc Natl Acad Sci U S A. 2005 September 6; 102(36): 12997. doi: 10.1073/pnas.0506663102.PMCID: PMC1200317 Corrects: Nina Jendreyko, et al. Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo. Proc Natl Acad Sci U S A. 2005 June 7; 102(23): 8293–8298. |
