| | This journal provides immediate access to some articles. From the Academy Statistical signals in bioinformatics Samuel Karlin PMCID: PMC1224616 Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences Yi Xing and Christopher Lee PMCID: PMC1224612 In This Issue Proc Natl Acad Sci U S A. 2005 September 20; 102(38): 13353–13354. doi: 10.1073/iti3805102.PMCID: PMC1224675 Commentaries Bugging the intestinal response to radiation Ralph R. Weichselbaum PMCID: PMC1224667 The LIGHT and DARC sides of herpesvirus entry mediator Tania H. Watts and Jennifer L. Gommerman PMCID: PMC1224668 Perspective Eusociality: Origin and consequences Edward O. Wilson and Bert Hölldobler PMCID: PMC1224642 Physical Sciences Chemistry Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12 Daniel A. Calarese, Hing-Ken Lee, Cheng-Yuan Huang, Michael D. Best, Rena D. Astronomo, Robyn L. Stanfield, Hermann Katinger, Dennis R. Burton, Chi-Huey Wong, and Ian A. Wilson PMCID: PMC1224641 From the Cover:
Probing the structure of a rotaxane with two-dimensional infrared spectroscopy Olaf F. A. Larsen, Pavol Bodis, Wybren Jan Buma, Jeffrey S. Hannam, David A. Leigh, and Sander Woutersen PMCID: PMC1198997 Defined DNA/nanoparticle conjugates Christopher J. Ackerson, Michael T. Sykes, and Roger D. Kornberg PMCID: PMC1200880 Induced helicity in biopolymer networks under stress S. Courty, J. L. Gornall, and E. M. Terentjev PMCID: PMC1224673 Statistics Discovering statistically significant pathways in expression profiling studies Lu Tian, Steven A. Greenberg, Sek Won Kong, Josiah Altschuler, Isaac S. Kohane, and Peter J. Park PMCID: PMC1200092 Biological Sciences Agricultural Sciences The endophytic fungus Piriformospora indica reprograms barley to salt-stress tolerance, disease resistance, and higher yield Frank Waller, Beate Achatz, Helmut Baltruschat, József Fodor, Katja Becker, Marina Fischer, Tobias Heier, Ralph Hückelhoven, Christina Neumann, Diter von Wettstein, Philipp Franken, and Karl-Heinz Kogel PMCID: PMC1224632 Biochemistry Crystal structure of a bacterial ribonuclease P RNA Alexei V. Kazantsev, Angelika A. Krivenko, Daniel J. Harrington, Stephen R. Holbrook, Paul D. Adams, and Norman R. Pace PMCID: PMC1224664 Extensive 3′ modification of plant small RNAs is modulated by helper component-proteinase expression H. Alexander Ebhardt, Emily P. Thi, Ming-Bo Wang, and Peter J. Unrau PMCID: PMC1224661 Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1 Toshiyuki Nakamura, Norihito Shibata, Takako Nishimoto-Shibata, Dongdong Feng, Mamoru Ikemoto, Kiyoto Motojima, Naoyuki Iso-o, Kazuhisa Tsukamoto, Masafumi Tsujimoto, and Hiroyuki Arai PMCID: PMC1224665 Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing Shengbing Huang, Hui Zhou, David Katzmann, Mark Hochstrasser, Elena Atanasova, and Zhiguo Zhang PMCID: PMC1224646 Inorganic polyphosphate in the social life of Myxococcus xanthus: Motility, development, and predation Haiyu Zhang, Narayan N. Rao, Toshikazu Shiba, and Arthur Kornberg PMCID: PMC1224657 Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation Patrick Hundsdoerfer, Christian Thoma, and Matthias W. Hentze PMCID: PMC1224658 Biophysics Dissecting the mechanical unfolding of ubiquitin Anders Irbäck, Simon Mitternacht, and Sandipan Mohanty PMCID: PMC1224613 Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases Roger S. Armen, Brady M. Bernard, Ryan Day, Darwin O. V. Alonso, and Valerie Daggett PMCID: PMC1224618 Eukaryotic cells are dynamically ordered or critical but not chaotic Ilya Shmulevich, Stuart A. Kauffman, and Maximino Aldana PMCID: PMC1224670 Ensemble versus single-molecule protein unfolding Ryan Day and Valerie Daggett PMCID: PMC1224615 Reversible inhibition of copper amine oxidase activity by channel-blocking ruthenium(II) and rhenium(I) molecular wires Stephen M. Contakes, Gregory A. Juda, David B. Langley, Nicholas W. Halpern-Manners, Anthony P. Duff, Alexander R. Dunn, Harry B. Gray, David M. Dooley, J. Mitchell Guss, and Hans C. Freeman PMCID: PMC1224652 Induced helicity in biopolymer networks under stress S. Courty, J. L. Gornall, and E. M. Terentjev PMCID: PMC1224673 Cell Biology Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein Olav M. Andersen, Juliane Reiche, Vanessa Schmidt, Michael Gotthardt, Robert Spoelgen, Joachim Behlke, Christine A. F. von Arnim, Tilman Breiderhoff, Pernille Jansen, Xin Wu, Kelly R. Bales, Roberto Cappai, Colin L. Masters, Jørgen Gliemann, Elliott J. Mufson, Bradley T. Hyman, Steven M. Paul, Anders Nykjær, and Thomas E. Willnow PMCID: PMC1224625 Distinct functional units of the Golgi complex in Drosophila cells Hiroyuki Yano, Miki Yamamoto-Hino, Masato Abe, Reiko Kuwahara, Shuka Haraguchi, Isamu Kusaka, Wakae Awano, Akiko Kinoshita-Toyoda, Hidenao Toyoda, and Satoshi Goto PMCID: PMC1224666 Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis Sara O. Dean, Stephen L. Rogers, Nico Stuurman, Ronald D. Vale, and James A. Spudich PMCID: PMC1200093 An interaction between αvβ8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain Joseph H. McCarty, Aaron A. Cook, and Richard O. Hynes PMCID: PMC1224645 Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth Lei Wang, Linda Yang, Kevin Burns, Chia-Yi Kuan, and Yi Zheng PMCID: PMC1224631 Developmental Biology Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules Xuan Chi, Pradeep K. Chatterjee, Willie Wilson, III, Shu-Xing Zhang, Franco J. DeMayo, and Robert J. Schwartz PMCID: PMC1224629 From the Cover:
A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49 Marc R. Van Gilst, Haralambos Hadjivassiliou, and Keith R. Yamamoto PMCID: PMC1201344 Cooperative interaction of Angiopoietin-like proteins 1 and 2 in zebrafish vascular development Yoshiaki Kubota, Yuichi Oike, Shinya Satoh, Yoko Tabata, Yuichi Niikura, Tohru Morisada, Masaki Akao, Takashi Urano, Yasuhiro Ito, Takeshi Miyamoto, Norihiro Nagai, Gou Young Koh, Sumiko Watanabe, and Toshio Suda PMCID: PMC1224617 Ecology Reproductive benefits derived from defensive plant alkaloid possession in an arctiid moth (Utetheisa ornatrix) Marta L. del Campo, Scott R. Smedley, and Thomas Eisner PMCID: PMC1224640 Small-scale field experiments accurately scale up to predict density dependence in reef fish populations at large scales Mark A. Steele and Graham E. Forrester PMCID: PMC1224630 From the Cover:
Increased salinization of fresh water in the northeastern United States Sujay S. Kaushal, Peter M. Groffman, Gene E. Likens, Kenneth T. Belt, William P. Stack, Victoria R. Kelly, Lawrence E. Band, and Gary T. Fisher PMCID: PMC1224654 Environmental Sciences Satellite-observed photosynthetic trends across boreal North America associated with climate and fire disturbance Scott J. Goetz, Andrew G. Bunn, Gregory J. Fiske, and R. A. Houghton PMCID: PMC1224647 Evolution Evidence of functional selection pressure for alternative splicing events that accelerate evolution of protein subsequences Yi Xing and Christopher Lee PMCID: PMC1224612 Genetics Statistical methods for identifying yeast cell cycle transcription factors Huai-Kuang Tsai, Henry Horng-Shing Lu, and Wen-Hsiung Li PMCID: PMC1224643 UVA radiation is highly mutagenic in cells that are unable to repair 7,8-dihydro-8-oxoguanine in Saccharomyces cerevisiae S. Kozmin, G. Slezak, A. Reynaud-Angelin, C. Elie, Y. de Rycke, S. Boiteux, and E. Sage PMCID: PMC1224634 Discovering statistically significant pathways in expression profiling studies Lu Tian, Steven A. Greenberg, Sek Won Kong, Josiah Altschuler, Isaac S. Kohane, and Peter J. Park PMCID: PMC1200092 From the Cover:
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival Lance D. Miller, Johanna Smeds, Joshy George, Vinsensius B. Vega, Liza Vergara, Alexander Ploner, Yudi Pawitan, Per Hall, Sigrid Klaar, Edison T. Liu, and Jonas Bergh PMCID: PMC1197273 Immunology Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12 Daniel A. Calarese, Hing-Ken Lee, Cheng-Yuan Huang, Michael D. Best, Rena D. Astronomo, Robyn L. Stanfield, Hermann Katinger, Dennis R. Burton, Chi-Huey Wong, and Ian A. Wilson PMCID: PMC1224641 The anti-tetanus immune response of neonatal mice is augmented by retinoic acid combined with polyriboinosinic:polyribocytidylic acid Yifan Ma and A. Catharine Ross PMCID: PMC1224655 Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders Alejo Chorny, Elena Gonzalez-Rey, Amelia Fernandez-Martin, David Pozo, Doina Ganea, and Mario Delgado PMCID: PMC1224633 Transgenic alteration of Toll immune pathway in the female mosquito Aedes aegypti Guowu Bian, Sang Woon Shin, Hyang-Mi Cheon, Vladimir Kokoza, and Alexander S. Raikhel PMCID: PMC1224621 A requirement for sustained ERK signaling during thymocyte positive selection in vivo Lisa K. McNeil, Timothy K. Starr, and Kristin A. Hogquist PMCID: PMC1224638 Medical Sciences Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis Yasuhiro Yamada, Laurie Jackson-Grusby, Heinz Linhart, Alex Meissner, Amir Eden, Haijiang Lin, and Rudolf Jaenisch PMCID: PMC1224663 Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency Oumeya Adjali, Rita R. Vicente, Christophe Ferrand, Chantal Jacquet, Cédric Mongellaz, Pierre Tiberghien, Karim Chebli, Valérie S. Zimmermann, and Naomi Taylor PMCID: PMC1224628 Reversal of amyloid-induced heart disease in desmin-related cardiomyopathy Atsushi Sanbe, Hanna Osinska, Chet Villa, James Gulick, Raisa Klevitsky, Charles G. Glabe, Rakez Kayed, and Jeffrey Robbins PMCID: PMC1224623 Structural models for the protein family characterized by gamete surface protein Pfs230 of Plasmodium falciparum Dietlind L. Gerloff, Alison Creasey, Siarhei Maslau, and Richard Carter PMCID: PMC1224620 Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues Qi Chen, Michael Graham Espey, Murali C. Krishna, James B. Mitchell, Christopher P. Corpe, Garry R. Buettner, Emily Shacter, and Mark Levine PMCID: PMC1224653 Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation Sang Hoon Rhee, Eunok Im, Martin Riegler, Efi Kokkotou, Michael O'Brien, and Charalabos Pothoulakis PMCID: PMC1224619 The B1-subunit of the H+ ATPase is required for maximal urinary acidification Karin E. Finberg, Carsten A. Wagner, Matthew A. Bailey, Teodor G. Păunescu, Sylvie Breton, Dennis Brown, Gerhard Giebisch, John P. Geibel, and Richard P. Lifton PMCID: PMC1224669 The kinase inhibitor imatinib mesylate inhibits TNF-α production in vitro and prevents TNF-dependent acute hepatic inflammation Anna Maria Wolf, Dominik Wolf, Holger Rumpold, Susanne Ludwiczek, Barbara Enrich, Guenther Gastl, Guenter Weiss, and Herbert Tilg PMCID: PMC1224614 Correction of chromosomal mutation and random integration in embryonic stem cells with helper-dependent adenoviral vectors Fumi Ohbayashi, Michael A. Balamotis, Atsuhiro Kishimoto, Emi Aizawa, Arturo Diaz, Paul Hasty, Frank L. Graham, C. Thomas Caskey, and Kohnosuke Mitani PMCID: PMC1224662 Microbiology How adeno-associated virus Rep78 protein arrests cells completely in S phase Carole Berthet, Kenneth Raj, Philippe Saudan, and Peter Beard PMCID: PMC1224635 Viral targeting of the interferon-β-inducing Traf family member-associated NF-κB activator (TANK)-binding kinase-1 Gunhild Unterstab, Stephan Ludwig, Aline Anton, Oliver Planz, Bianca Dauber, Daniel Krappmann, Gudrun Heins, Christina Ehrhardt, and Thorsten Wolff PMCID: PMC1224622 Use of RNA interference in Drosophila S2 cells to identify host pathways controlling compartmentalization of an intracellular pathogen Luisa W. Cheng, Julie P. M. Viala, Nico Stuurman, Ursula Wiedemann, Ronald D. Vale, and Daniel A. Portnoy PMCID: PMC1224656 Neuroscience Cytoskeletal coordination during neuronal migration Bruce T. Schaar and Susan K. McConnell PMCID: PMC1199551 Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle T. Michael Redmond, Eugenia Poliakov, Shirley Yu, Jen-Yue Tsai, Zhongjian Lu, and Susan Gentleman PMCID: PMC1224626 Encoding of learned importance of sound by magnitude of representational area in primary auditory cortex Richard G. Rutkowski and Norman M. Weinberger PMCID: PMC1200094 Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling Yufeng Yang, Stephan Gehrke, Md. Emdadul Haque, Yuzuru Imai, Jon Kosek, Lichuan Yang, M. Flint Beal, Isao Nishimura, Kazumasa Wakamatsu, Shosuke Ito, Ryosuke Takahashi, and Bingwei Lu PMCID: PMC1224636 Pharmacology The antimalarial drug artemisinin alkylates heme in infected mice Anne Robert, Françoise Benoit-Vical, Catherine Claparols, and Bernard Meunier PMCID: PMC1224611 l-citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits Toshio Hayashi, Packiasamy A. R. Juliet, Hisako Matsui-Hirai, Asaka Miyazaki, Akiko Fukatsu, Jun Funami, Akihisa Iguchi, and Louis J. Ignarro PMCID: PMC1224660 Plant Biology Vitamin B6 biosynthesis in higher plants Marina Tambasco-Studart, Olca Titiz, Thomas Raschle, Gabriela Forster, Nikolaus Amrhein, and Teresa B. Fitzpatrick PMCID: PMC1224648 The putative high-affinity nitrate transporter NRT2.1 represses lateral root initiation in response to nutritional cues Daniel Y. Little, Hongyu Rao, Sabrina Oliva, Françoise Daniel-Vedele, Anne Krapp, and Jocelyn E. Malamy PMCID: PMC1224627 AtFtsH6 is involved in the degradation of the light-harvesting complex II during high-light acclimation and senescence Agnieszka Żelisko, Maribel García-Lorenzo, Grzegorz Jackowski, Stefan Jansson, and Christiane Funk PMCID: PMC1224624 From the Cover:
A chimeric photoreceptor gene, NEOCHROME, has arisen twice during plant evolution Noriyuki Suetsugu, Franz Mittmann, Gottfried Wagner, Jon Hughes, and Masamitsu Wada PMCID: PMC1224637 Correction Proc Natl Acad Sci U S A. 2005 September 20; 102(38): 13710. doi: 10.1073/pnas.0506917102.PMCID: PMC1224674 Corrects: Kohjiro Ueki, et al. Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. Proc Natl Acad Sci U S A. 2004 July 13; 101(28): 10422–10427. |
