Perspectives
Editorials
- Toxicogenomics: An EHP Section-Kenneth S. Ramos and Thomas J. Goehl
p. A 328 [HTML]
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- Model Selection in Genomics-Ilya Shmulevich
p. A 328 [HTML]
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- On the 50th Anniversary of Solving the Structure of DNA-Leona D. Samson
p. A 328 [HTML]
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Environews
Forum
- Toxicogenomics: Roadblocks and New Directions
- Rapamycin Throws a Master Switch
- TXG at SOT
- Putting Proteins in One Place
p. A 334
- TXGnet: Bioinformatics Organization
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NCT Update
Focus
Data Explosion: Bringing Order to Chaos with Bioinformatics
p. A 340
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Science Selections
- Liver Library
- Monitoring Estrogenic Effects
- Metals Leave Their Mark
p. A 346
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Toxicogenomics
Commentaries
The Comparative Toxicogenomics Database (CTD)
Carolyn J. Mattingly, Glenn T. Colby, John N. Forrest, and James L.
Boyer
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The Human Proteome Organization (HUPO) and Environmental Health
B. Alex Merrick
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Application of Toxicogenomic Analysis to Risk Assessment of Delayed
Long-Term Effects of Multiple Chemicals, Including Endocrine Disruptors
in Human Fetuses
Chisato Mori, Masatoshi Komiyama, Tetsuya Adachi, Kenichi Sakurai, Daisuke
Nishimura, Kyoka Takashima, and Emiko Todaka
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Review
Systems Toxicology and the Chemical Effects in Biological Systems (CEBS)
Knowledge Base
Michael Waters, Gary Boorman, Pierre Bushel, Michael Cunningham, Rick
Irwin, Alex Merrick, Kenneth Olden, Richard Paules, James Selkirk, Stanley
Stasiewicz, Brenda Weis, Ben Van Houten, Nigel Walker, and Raymond Tennant
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Articles
Genomic and Proteomic Profiling of Responses to Toxic Metals in Human
Lung Cells
Angeline S. Andrew, Amy J. Warren, Aaron Barchowsky, Kaili A.Temple,
Linda Klei, Nicole V. Soucy, Kimberley A. O'Hara, and Joshua W. Hamilton
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Expression Profiling of Estrogenic Compounds Using a Sheepshead Minnow
cDNA Macroarray
Patrick Larkin, Leroy C. Folmar, Michael J. Hemmer, Arianna J. Poston,
and Nancy D. Denslow
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Gene Expression Profiles Associated with Inflammation, Fibrosis, and
Cholestasis in Mouse Liver after Griseofulvin
Timothy W. Gant, Petra R. Baus, Bruce Clothier, Joan Riley, Reginald
Davies, David J. Judah, Richard E. Edwards, Elisabeth George, Peter
Greaves, and Andrew G. Smith
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Intrinsic Hepatic Phenotype Associated with the Cyp1a2 Gene
as Shown by cDNA Expression Microarray Analysis of the Knockout Mouse
Andrew G. Smith, Reginald Davies, Timothy P. Dalton, Marian L. Miller,
David Judah, Joan Riley, Timothy Gant, and Daniel W. Nebert
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Development of a DNA Microarray for Toxicology Based on Hepatotoxin-Regulated
Sequences
Jeffrey F. Waring, Guy Cavet, Robert A. Jolly, Jeff McDowell, Hongye
Dai, Rita Ciurlionis, Chunsheng Zhang, Roland Stoughton, Pek Lum, Allan
Ferguson, Christopher J. Roberts, and Roger G. Ulrich
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Meeting Report
Exploiting Genome Data to Understand the Function, Regulation, and
Evolutionary Origins of Toxicologically Relevant Genes
Nazzareno Ballatori, James L. Boyer, and John C. Rockett
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