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| Paved surfaces cover an estimated 43,000 square miles in the United States, and nearly a quarter million acres are paved or repaved each year. The result of all of this impervious surface area is that rainwater often has nowhere to go. The Focus article (p. A456) examines the consequences of runoff--often containing toxic chemicals--on surrounding waterways and what it may mean for human and ecological health.
image credit: Shutterstock Purchase This Issue | |
Perspectives
Director's Perspective
p. A 440
Correspondence
p. A 442
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Environews
Forum
p. A 448
NIEHS News
p. A 452
Focus
p. A 456
Spheres of Influence
p. A 464
Innovations
p. A 468
Science Selections
p. A 472
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Commentaries & Reviews
TOXICOLOGY|Vinyl Chloride: A Case Study of Data Suppression and Misrepresentation
Jennifer Beth Sass, Barry Castleman, and David Wallinga
p. 809 [ Abstract ] [ Full ] [ PDF ]
ETHICS|Pesticide Testing on Human Subjects: Weighing Benefits and Risks
David B. Resnik and Christopher Portier
p. 813 [ Abstract ] [ Full ] [ PDF ]
TOXICOGENOMICS|Ushering in the New Toxicology: Toxicogenomics and the Public Interest
John M. Balbus
p. 818 [ Abstract ] [ Full ] [ PDF ]
NANOTECHNOLOGY|Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles
Günter Oberdörster, Eva Oberdörster, and Jan Oberdörster
p. 823 [ Abstract ] [ Full ] [ PDF ]
EXPOSURE ASSESSMENT|Personalized Exposure Assessment: Promising Approaches for Human Environmental Health Research
Brenda K. Weis, David Balshaw, John R. Barr, David Brown, Mark Ellisman, Paul Lioy, Gilbert Omenn, John D. Potter, Martyn T. Smith, Lydia Sohn, William A. Suk, Susan Sumner, James Swenberg, David R. Walt, Simon Watkins, Claudia Thompson, and Samuel H. Wilson
p. 840 [ Abstract ] [ Full ] [ PDF ]
Research
RESPIRATORY DISEASE|Changes in Levels of Nerve Growth Factor in Nasal Secretions after Capsaicin Inhalation in Patients with Airway Symptoms from Scents and Chemicals
Eva Millqvist, Ewa Ternesten-Hasséus, Arne Ståhl, and Mats Bende
p. 849 [ Abstract ] [ Full ] [ PDF ]
RISK CHARACTERIZATION|Lipid Adjustment in the Analysis of Environmental Contaminants and Human Health Risks
Enrique F. Schisterman, Brian W. Whitcomb, Germaine M. Buck Louis, and Thomas A. Louis
p. 853 [ Abstract ] [ Full ] [ PDF ]
REPRODUCTIVE HEALTH|Serum Dioxin Concentrations and Age at Menopause
Brenda Eskenazi, Marcella Warner, Amy R. Marks, Steven Samuels, Pier Mario Gerthoux, Paolo Vercellini, David L. Olive, Larry Needham, Donald G. Patterson Jr., and Paolo Mocarelli
p. 858 [ Abstract ] [ Full ] [ PDF ]
EXPOSURE ASSESSMENT|Influence of Tap Water Quality and Household Water Use Activities on Indoor Air and Internal Dose Levels of Trihalomethanes
John R. Nuckols, David L. Ashley, Christopher Lyu, Sydney M. Gordon, Alison F. Hinckley, and Philip Singer
 Also see Science Selections, p. A474
p. 863 [ Abstract ] [ Full ] [ PDF ]
NEURODEVELOPMENT|Polychlorinated Biphenyls Disturb Differentiation of Normal Human Neural Progenitor Cells: Clue for Involvement of Thyroid Hormone Receptors
Ellen Fritsche, Jason E. Cline, Ngoc-Ha Nguyen, Thomas S. Scanlan, and Josef Abel
Also see Science Selections, p. A472
p. 871 [ Abstract ] [ Full ] [ PDF ]
Environmental Medicine
NEUROBEHAVIORAL DISEASE|Neurologic Symptoms in Licensed Private Pesticide Applicators in the Agricultural Health Study
Freya Kamel, Lawrence S. Engel, Beth C. Gladen, Jane A. Hoppin, Michael C. R. Alavanja, and Dale P. Sandler
Also see Science Selections, p. A472
p. 877 [ Abstract ] [ Full ] [ PDF ]
CARDIOVASCULAR DISEASE|Air Pollution and ST-Segment Depression in Elderly Subjects
Diane R. Gold, Augusto A. Litonjua, Antonella Zanobetti, Brent A. Coull, Joel Schwartz, Gail MacCallum, Richard L. Verrier, Bruce D. Nearing, Marina J. Canner, Helen Suh, and Peter H. Stone
p. 883 [ Abstract ] [ Full ] [ PDF ]
ASTHMA|Grand Rounds: Latex-Induced Occupational Asthma in a Surgical Pathologist
Judith Green-McKenzie and Debra Hudes
p. 888 [ Abstract ] [ Full ] [ PDF ]
Children's Health
NEURODEVELOPMENT|Low-Level Environmental Lead Exposure and Children's Intellectual Function: An International Pooled Analysis
Bruce P. Lanphear, Richard Hornung, Jane Khoury, Kimberly Yolton, Peter Baghurst, David C. Bellinger, Richard L. Canfield, Kim N. Dietrich, Robert Bornschein, Tom Greene, Stephen J. Rothenberg, Herbert L. Needleman, Lourdes Schnaas, Gail Wasserman, Joseph Graziano, and Russell Roberts
Also see Science Selections, p. A473
p. 894 [ Abstract ] [ Full ] [ PDF ]
RESPIRATORY DISEASE|Blood Lead Level and Risk of Asthma
Christine L.M. Joseph, Suzanne Havstad, Dennis R. Ownby, Edward L. Peterson, Mary Maliarik, Michael J. McCabe Jr., Charles Barone, and Christine Cole Johnson
p. 900 [ Abstract ] [ Full ] [ PDF ]
EXPOSURE ASSESSMENT|Umbilical Cord Mercury Concentration as Biomarker of Prenatal Exposure to Methylmercury
Philippe Grandjean, Esben Budtz-Jørgensen, Poul J. Jørgensen, and Pál Weihe
p. 905 [ Abstract ] [ Full ] [ PDF ]
CANCER|Risk of Brain Tumors in Children and Susceptibility to Organophosphorus Insecticides: The Potential Role of Paraoxonase (PON1)
Susan Searles Nielsen, Beth A. Mueller, Anneclaire J. De Roos, Hannah-Malia A. Viernes, Federico M. Farin, and Harvey Checkoway
p. 909 [ Abstract ] [ Full ] [ PDF ]
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