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Volume 4(7);  July 2008
Perspective
Outlook on Thailand's Genomics and Computational Biology Research and Development
Wannipha Tongsima, Sissades Tongsima, and Prasit Palittapongarnpim
PLoS Comput Biol. 2008 July; 4(7): e1000115. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000115.
PMCID: PMC2446437
Computational Biology Resources Lack Persistence and Usability
Stella Veretnik, J. Lynn Fink, and Philip E. Bourne
PLoS Comput Biol. 2008 July; 4(7): e1000136. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000136.
PMCID: PMC2443418
Message from ISCB
ISCB Honors David Haussler and Aviv Regev
Clare Sansom and B. J. Morrison McKay
PLoS Comput Biol. 2008 July; 4(7): e1000101. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000101.
PMCID: PMC2536508
Review
Nonnegative Matrix Factorization: An Analytical and Interpretive Tool in Computational Biology
Karthik Devarajan
PLoS Comput Biol. 2008 July; 4(7): e1000029. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000029.
PMCID: PMC2447881
Research Articles
Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic Cytokinesis
Ivan V. Surovtsev, Jeffrey J. Morgan, and Paul A. Lindahl
PLoS Comput Biol. 2008 July; 4(7): e1000102. Published online 2008 July 4. doi: 10.1371/journal.pcbi.1000102.
PMCID: PMC2432035
Dynamics of Immune Escape during HIV/SIV Infection
Christian L. Althaus and Rob J. De Boer
PLoS Comput Biol. 2008 July; 4(7): e1000103. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000103.
PMCID: PMC2423483
Circadian Phase Resetting via Single and Multiple Control Targets
Neda Bagheri, Jörg Stelling, and Francis J. Doyle, III
PLoS Comput Biol. 2008 July; 4(7): e1000104. Published online 2008 July 4. doi: 10.1371/journal.pcbi.1000104.
PMCID: PMC2536509
Local Function Conservation in Sequence and Structure Space
Nils Weinhold, Oliver Sander, Francisco S. Domingues, Thomas Lengauer, and Ingolf Sommer
PLoS Comput Biol. 2008 July; 4(7): e1000105. Published online 2008 July 4. doi: 10.1371/journal.pcbi.1000105.
PMCID: PMC2427199
Increased Brain Signal Variability Accompanies Lower Behavioral Variability in Development
Anthony Randal McIntosh, Natasa Kovacevic, and Roxane J. Itier
PLoS Comput Biol. 2008 July; 4(7): e1000106. Published online 2008 July 4. doi: 10.1371/journal.pcbi.1000106.
PMCID: PMC2429973
Quantitative Predictions of Peptide Binding to Any HLA-DR Molecule of Known Sequence: NetMHCIIpan
Morten Nielsen, Claus Lundegaard, Thomas Blicher, Bjoern Peters, Alessandro Sette, Sune Justesen, Søren Buus, and Ole Lund
PLoS Comput Biol. 2008 July; 4(7): e1000107. Published online 2008 July 4. doi: 10.1371/journal.pcbi.1000107.
PMCID: PMC2430535
Unraveling Protein Networks with Power Graph Analysis
Loïc Royer, Matthias Reimann, Bill Andreopoulos, and Michael Schroeder
PLoS Comput Biol. 2008 July; 4(7): e1000108. Published online 2008 July 11. doi: 10.1371/journal.pcbi.1000108.
PMCID: PMC2424176
The Generation of Promoter-Mediated Transcriptional Noise in Bacteria
Namiko Mitarai, Ian B. Dodd, Michael T. Crooks, and Kim Sneppen
PLoS Comput Biol. 2008 July; 4(7): e1000109. Published online 2008 July 11. doi: 10.1371/journal.pcbi.1000109.
PMCID: PMC2442219
The Ascent of the Abundant: How Mutational Networks Constrain Evolution
Matthew C. Cowperthwaite, Evan P. Economo, William R. Harcombe, Eric L. Miller, and Lauren Ancel Meyers
PLoS Comput Biol. 2008 July; 4(7): e1000110. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000110.
PMCID: PMC2430528
Active Nuclear Receptors Exhibit Highly Correlated AF-2 Domain Motions
Denise G. Teotico, Monica L. Frazier, Feng Ding, Nikolay V. Dokholyan, Brenda R. S. Temple, and Matthew R. Redinbo
PLoS Comput Biol. 2008 July; 4(7): e1000111. Published online 2008 July 11. doi: 10.1371/journal.pcbi.1000111.
PMCID: PMC2432469
Evolution of Evolvability in Gene Regulatory Networks
Anton Crombach and Paulien Hogeweg
PLoS Comput Biol. 2008 July; 4(7): e1000112. Published online 2008 July 11. doi: 10.1371/journal.pcbi.1000112.
PMCID: PMC2432032
Decoding of Superimposed Traces Produced by Direct Sequencing of Heterozygous Indels
Dmitry A. Dmitriev and Roman A. Rakitov
PLoS Comput Biol. 2008 July; 4(7): e1000113. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000113.
PMCID: PMC2429969
Probing the Extent of Randomness in Protein Interaction Networks
Joseph Ivanic, Anders Wallqvist, and Jaques Reifman
PLoS Comput Biol. 2008 July; 4(7): e1000114. Published online 2008 July 11. doi: 10.1371/journal.pcbi.1000114.
PMCID: PMC2527968
Similarity Queries for Temporal Toxicogenomic Expression Profiles
Adam A. Smith, Aaron Vollrath, Christopher A. Bradfield, and Mark Craven
PLoS Comput Biol. 2008 July; 4(7): e1000116. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000116.
PMCID: PMC2453325
Predicting and Validating Protein Interactions Using Network Structure
Pao-Yang Chen, Charlotte M. Deane, and Gesine Reinert
PLoS Comput Biol. 2008 July; 4(7): e1000118. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000118.
PMCID: PMC2435280
Intrinsic Gain Modulation and Adaptive Neural Coding
Sungho Hong, Brian Nils Lundstrom, and Adrienne L. Fairhall
PLoS Comput Biol. 2008 July; 4(7): e1000119. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000119.
PMCID: PMC2440820
Using Expression Profiles of Caenorhabditis elegans Neurons To Identify Genes That Mediate Synaptic Connectivity
Leehod Baruch, Shalev Itzkovitz, Michal Golan-Mashiach, Ehud Shapiro, and Eran Segal
PLoS Comput Biol. 2008 July; 4(7): e1000120. Published online 2008 July 11. doi: 10.1371/journal.pcbi.1000120.
PMCID: PMC2517614
Memory Switches in Chemical Reaction Space
Naren Ramakrishnan and Upinder S. Bhalla
PLoS Comput Biol. 2008 July; 4(7): e1000122. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000122.
PMCID: PMC2440819
Emergent Synchronous Bursting of Oxytocin Neuronal Network
Enrico Rossoni, Jianfeng Feng, Brunello Tirozzi, David Brown, Gareth Leng, and Françoise Moos
PLoS Comput Biol. 2008 July; 4(7): e1000123. Published online 2008 July 18. doi: 10.1371/journal.pcbi.1000123.
PMCID: PMC2440533
Isolation-by-Distance and Outbreeding Depression Are Sufficient to Drive Parapatric Speciation in the Absence of Environmental Influences
Guy A. Hoelzer, Rich Drewes, Jeffrey Meier, and René Doursat
PLoS Comput Biol. 2008 July; 4(7): e1000126. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000126.
PMCID: PMC2440541
The Spatiotemporal Pattern of Src Activation at Lipid Rafts Revealed by Diffusion-Corrected FRET Imaging
Shaoying Lu, Mingxing Ouyang, Jihye Seong, Jin Zhang, Shu Chien, and Yingxiao Wang
PLoS Comput Biol. 2008 July; 4(7): e1000127. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000127.
PMCID: PMC2517613
Optimal Compensation for Temporal Uncertainty in Movement Planning
Todd E. Hudson, Laurence T. Maloney, and Michael S. Landy
PLoS Comput Biol. 2008 July; 4(7): e1000130. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000130.
PMCID: PMC2442880
Protein Complex Evolution Does Not Involve Extensive Network Rewiring
Teunis J. P. van Dam and Berend Snel
PLoS Comput Biol. 2008 July; 4(7): e1000132. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000132.
PMCID: PMC2517612
Prediction by Graph Theoretic Measures of Structural Effects in Proteins Arising from Non-Synonymous Single Nucleotide Polymorphisms
Tammy M. K. Cheng, Yu-En Lu, Michele Vendruscolo, Pietro Lio', and Tom L. Blundell
PLoS Comput Biol. 2008 July; 4(7): e1000135. Published online 2008 July 25. doi: 10.1371/journal.pcbi.1000135.
PMCID: PMC2447880
Correction
Correction: Modeling the Effects of Cell Cycle M-phase Transcriptional Inhibition on Circadian Oscillation
Bin Kang, Yuan-Yuan Li, Xiao Chang, Lei Liu, and Yi-Xue Li
PLoS Comput Biol. 2008 July; 4(7): 10.1371/annotation/3cf61cf0-5b5d-4550-adc8-42580b7a3540. Published online 2008 July 4. doi: 10.1371/annotation/3cf61cf0-5b5d-4550-adc8-42580b7a3540.
PMCID: PMC2648584
Corrects: Bin Kang, et al. Modeling the Effects of Cell Cycle M-phase Transcriptional Inhibition on Circadian Oscillation. PLoS Comput Biol. 2008 March; 4(3): e1000019.
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