| | Perspective Genome-Scale Computational Biology and Bioinformatics in Australia Mark A. Ragan, Tim Littlejohn, and Bruce Ross PLoS Comput Biol. 2008 August; 4(8): e1000068. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000068.PMCID: PMC2440818 Editorial Mean-Fields and Neural Masses Karl Friston PLoS Comput Biol. 2008 August; 4(8): e1000081. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000081.PMCID: PMC2435274 Message from ISCB Getting Started in Computational Immunology Steven H. Kleinstein PLoS Comput Biol. 2008 August; 4(8): e1000128. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000128.PMCID: PMC2518523 Review The Dynamic Brain: From Spiking Neurons to Neural Masses and Cortical
Fields Gustavo Deco, Viktor K. Jirsa, Peter A. Robinson, Michael Breakspear, and Karl Friston PLoS Comput Biol. 2008 August; 4(8): e1000092. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000092.PMCID: PMC2519166 Research Articles Geometric Interpretation of Gene Coexpression Network Analysis Steve Horvath and Jun Dong PLoS Comput Biol. 2008 August; 4(8): e1000117. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000117.PMCID: PMC2446438 Efficient Algorithms for Probing the RNA Mutation Landscape Jérôme Waldispühl, Srinivas Devadas, Bonnie Berger, and Peter Clote PLoS Comput Biol. 2008 August; 4(8): e1000124. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000124.PMCID: PMC2475669 Regulatory Control and the Costs and Benefits of Biochemical Noise Sorin Tănase-Nicola and Pieter Rein ten Wolde PLoS Comput Biol. 2008 August; 4(8): e1000125. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000125.PMCID: PMC2518519 Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements M. Cecchini, A. Houdusse, and M. Karplus PLoS Comput Biol. 2008 August; 4(8): e1000129. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000129.PMCID: PMC2497441 Modeling the Violation of Reward Maximization and Invariance in Reinforcement Schedules Giancarlo La Camera and Barry J. Richmond PLoS Comput Biol. 2008 August; 4(8): e1000131. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000131.PMCID: PMC2453237 Stroke Rehabilitation Reaches a Threshold Cheol E. Han, Michael A. Arbib, and Nicolas Schweighofer PLoS Comput Biol. 2008 August; 4(8): e1000133. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000133.PMCID: PMC2527783 Predicting Human Nucleosome Occupancy from Primary Sequence Shobhit Gupta, Jonathan Dennis, Robert E. Thurman, Robert Kingston, John A. Stamatoyannopoulos, and William Stafford Noble PLoS Comput Biol. 2008 August; 4(8): e1000134. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000134.PMCID: PMC2515632 Innate Visual Learning through Spontaneous Activity Patterns Mark V. Albert, Adam Schnabel, and David J. Field PLoS Comput Biol. 2008 August; 4(8): e1000137. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000137.PMCID: PMC2446436 Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers Jihua Hao, Adrian W. R. Serohijos, Gail Newton, Gina Tassone, Zuncai Wang, Dennis C. Sgroi, Nikolay V. Dokholyan, and James P. Basilion PLoS Comput Biol. 2008 August; 4(8): e1000138. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000138.PMCID: PMC2453235 A Model of Stimulus-Specific Neural Assemblies in the Insect Antennal Lobe Dominique Martinez and Noelia Montejo PLoS Comput Biol. 2008 August; 4(8): e1000139. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000139.PMCID: PMC2536510 Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality Elena Zotenko, Julian Mestre, Dianne P. O'Leary, and Teresa M. Przytycka PLoS Comput Biol. 2008 August; 4(8): e1000140. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000140.PMCID: PMC2467474 Embedding mRNA Stability in Correlation Analysis of Time-Series Gene Expression Data Lorenzo Farina, Alberto De Santis, Samanta Salvucci, Giorgio Morelli, and Ida Ruberti PLoS Comput Biol. 2008 August; 4(8): e1000141. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000141.PMCID: PMC2453326 Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies Ranyee A. Chiang, Andrej Sali, and Patricia C. Babbitt PLoS Comput Biol. 2008 August; 4(8): e1000142. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000142.PMCID: PMC2453236 Falling towards Forgetfulness: Synaptic Decay Prevents Spontaneous Recovery of Memory James V. Stone and Peter E. Jupp PLoS Comput Biol. 2008 August; 4(8): e1000143. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000143.PMCID: PMC2516185 Retroviral Integration Process in the Human Genome: Is It Really Non-Random? A New Statistical Approach Alessandro Ambrosi, Claudia Cattoglio, and Clelia Di Serio PLoS Comput Biol. 2008 August; 4(8): e1000144. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000144.PMCID: PMC2453317 Intramolecular Cohesion of Coils Mediated by Phenylalanine–Glycine Motifs in the Natively Unfolded Domain of a Nucleoporin V. V. Krishnan, Edmond Y. Lau, Justin Yamada, Daniel P. Denning, Samir S. Patel, Michael E. Colvin, and Michael F. Rexach PLoS Comput Biol. 2008 August; 4(8): e1000145. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000145.PMCID: PMC2475668 Classifying RNA-Binding Proteins Based on Electrostatic Properties Shula Shazman and Yael Mandel-Gutfreund PLoS Comput Biol. 2008 August; 4(8): e1000146. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000146.PMCID: PMC2518515 A General Definition and Nomenclature for Alternative Splicing Events Michael Sammeth, Sylvain Foissac, and Roderic Guigó PLoS Comput Biol. 2008 August; 4(8): e1000147. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000147.PMCID: PMC2467475 Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP Marc Turcotte, Wei Tang, and Elliott M. Ross PLoS Comput Biol. 2008 August; 4(8): e1000148. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000148.PMCID: PMC2518520 Host Control of Malaria Infections: Constraints on Immune and Erythropoeitic Response Kinetics Philip G. McQueen and F. Ellis McKenzie PLoS Comput Biol. 2008 August; 4(8): e1000149. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000149.PMCID: PMC2491590 Self Containment, a Property of Modular RNA Structures, Distinguishes microRNAs Miler T. Lee and Junhyong Kim PLoS Comput Biol. 2008 August; 4(8): e1000150. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000150.PMCID: PMC2517099 A Novel Three-Phase Model of Brain Tissue Microstructure Jana L. Gevertz and Salvatore Torquato PLoS Comput Biol. 2008 August; 4(8): e1000152. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000152.PMCID: PMC2495040 Structure and Dynamics of Interphase Chromosomes Angelo Rosa and Ralf Everaers PLoS Comput Biol. 2008 August; 4(8): e1000153. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000153.PMCID: PMC2515109 A Feature-Based Approach to Modeling Protein–DNA Interactions Eilon Sharon, Shai Lubliner, and Eran Segal PLoS Comput Biol. 2008 August; 4(8): e1000154. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000154.PMCID: PMC2516605 The Effect of a ΔK280 Mutation on the Unfolded State of a Microtubule-Binding Repeat in Tau Austin Huang and Collin M. Stultz PLoS Comput Biol. 2008 August; 4(8): e1000155. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000155.PMCID: PMC2494868 PhyloGibbs-MP: Module Prediction and Discriminative Motif-Finding by Gibbs Sampling Rahul Siddharthan PLoS Comput Biol. 2008 August; 4(8): e1000156. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000156.PMCID: PMC2518514 Nonlinear Muscles, Passive Viscoelasticity and Body Taper Conspire To Create Neuromechanical Phase Lags in Anguilliform Swimmers T. McMillen, T. Williams, and P. Holmes PLoS Comput Biol. 2008 August; 4(8): e1000157. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000157.PMCID: PMC2518218 Modeling ChIP Sequencing In Silico with Applications Zhengdong D. Zhang, Joel Rozowsky, Michael Snyder, Joseph Chang, and Mark Gerstein PLoS Comput Biol. 2008 August; 4(8): e1000158. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000158.PMCID: PMC2507756 Combining Structural Connectivity and Response Latencies to Model the Structure of the Visual System Michael Capalbo, Eric Postma, and Rainer Goebel PLoS Comput Biol. 2008 August; 4(8): e1000159. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000159.PMCID: PMC2507758 Biophysical Parameters Modification Could Overcome Essential Hearing Gaps A. Kern, C. Heid, W.-H. Steeb, N. Stoop, and R. Stoop PLoS Comput Biol. 2008 August; 4(8): e1000161. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000161.PMCID: PMC2516184 Inference of Protein Complex Activities from Chemical-Genetic Profile and Its Applications: Predicting Drug-Target Pathways Sangjo Han and Dongsup Kim PLoS Comput Biol. 2008 August; 4(8): e1000162. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000162.PMCID: PMC2515108 Cooperative Transition between Open and Closed Conformations in Potassium Channels Turkan Haliloglu and Nir Ben-Tal PLoS Comput Biol. 2008 August; 4(8): e1000164. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000164.PMCID: PMC2528004 Network Inference Algorithms Elucidate Nrf2 Regulation of Mouse Lung Oxidative Stress Ronald C. Taylor, George Acquaah-Mensah, Mudita Singhal, Deepti Malhotra, and Shyam Biswal PLoS Comput Biol. 2008 August; 4(8): e1000166. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000166.PMCID: PMC2516606 Noise Reduction by Diffusional Dissipation in a Minimal Quorum Sensing Motif Yu Tanouchi, Dennis Tu, Jungsang Kim, and Lingchong You PLoS Comput Biol. 2008 August; 4(8): e1000167. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000167.PMCID: PMC2507755 Correction Correction: Classifying RNA-Binding Proteins Based on Electrostatic Properties Shula Shazman and Yael Mandel-Gutfreund PLoS Comput Biol. 2008 August; 4(8): 10.1371/annotation/be4eb7dd-4092-49c1-a619-e8eeba40ed67. Published online 2008 August 21. doi: 10.1371/annotation/be4eb7dd-4092-49c1-a619-e8eeba40ed67.PMCID: PMC2651598 Corrects: Shula Shazman, et al. Classifying RNA-Binding Proteins Based on Electrostatic Properties. PLoS Comput Biol. 2008 August; 4(8): e1000146. |