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Volume 4(8);  August 2008
Perspective
Genome-Scale Computational Biology and Bioinformatics in Australia
Mark A. Ragan, Tim Littlejohn, and Bruce Ross
PLoS Comput Biol. 2008 August; 4(8): e1000068. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000068.
PMCID: PMC2440818
Editorial
Mean-Fields and Neural Masses
Karl Friston
PLoS Comput Biol. 2008 August; 4(8): e1000081. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000081.
PMCID: PMC2435274
Message from ISCB
Getting Started in Computational Immunology
Steven H. Kleinstein
PLoS Comput Biol. 2008 August; 4(8): e1000128. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000128.
PMCID: PMC2518523
Review
The Dynamic Brain: From Spiking Neurons to Neural Masses and Cortical Fields
Gustavo Deco, Viktor K. Jirsa, Peter A. Robinson, Michael Breakspear, and Karl Friston
PLoS Comput Biol. 2008 August; 4(8): e1000092. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000092.
PMCID: PMC2519166
Research Articles
Geometric Interpretation of Gene Coexpression Network Analysis
Steve Horvath and Jun Dong
PLoS Comput Biol. 2008 August; 4(8): e1000117. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000117.
PMCID: PMC2446438
Efficient Algorithms for Probing the RNA Mutation Landscape
Jérôme Waldispühl, Srinivas Devadas, Bonnie Berger, and Peter Clote
PLoS Comput Biol. 2008 August; 4(8): e1000124. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000124.
PMCID: PMC2475669
Regulatory Control and the Costs and Benefits of Biochemical Noise
Sorin Tănase-Nicola and Pieter Rein ten Wolde
PLoS Comput Biol. 2008 August; 4(8): e1000125. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000125.
PMCID: PMC2518519
Allosteric Communication in Myosin V: From Small Conformational Changes to Large Directed Movements
M. Cecchini, A. Houdusse, and M. Karplus
PLoS Comput Biol. 2008 August; 4(8): e1000129. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000129.
PMCID: PMC2497441
Modeling the Violation of Reward Maximization and Invariance in Reinforcement Schedules
Giancarlo La Camera and Barry J. Richmond
PLoS Comput Biol. 2008 August; 4(8): e1000131. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000131.
PMCID: PMC2453237
Stroke Rehabilitation Reaches a Threshold
Cheol E. Han, Michael A. Arbib, and Nicolas Schweighofer
PLoS Comput Biol. 2008 August; 4(8): e1000133. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000133.
PMCID: PMC2527783
Predicting Human Nucleosome Occupancy from Primary Sequence
Shobhit Gupta, Jonathan Dennis, Robert E. Thurman, Robert Kingston, John A. Stamatoyannopoulos, and William Stafford Noble
PLoS Comput Biol. 2008 August; 4(8): e1000134. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000134.
PMCID: PMC2515632
Innate Visual Learning through Spontaneous Activity Patterns
Mark V. Albert, Adam Schnabel, and David J. Field
PLoS Comput Biol. 2008 August; 4(8): e1000137. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000137.
PMCID: PMC2446436
Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers
Jihua Hao, Adrian W. R. Serohijos, Gail Newton, Gina Tassone, Zuncai Wang, Dennis C. Sgroi, Nikolay V. Dokholyan, and James P. Basilion
PLoS Comput Biol. 2008 August; 4(8): e1000138. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000138.
PMCID: PMC2453235
A Model of Stimulus-Specific Neural Assemblies in the Insect Antennal Lobe
Dominique Martinez and Noelia Montejo
PLoS Comput Biol. 2008 August; 4(8): e1000139. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000139.
PMCID: PMC2536510
Why Do Hubs in the Yeast Protein Interaction Network Tend To Be Essential: Reexamining the Connection between the Network Topology and Essentiality
Elena Zotenko, Julian Mestre, Dianne P. O'Leary, and Teresa M. Przytycka
PLoS Comput Biol. 2008 August; 4(8): e1000140. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000140.
PMCID: PMC2467474
Embedding mRNA Stability in Correlation Analysis of Time-Series Gene Expression Data
Lorenzo Farina, Alberto De Santis, Samanta Salvucci, Giorgio Morelli, and Ida Ruberti
PLoS Comput Biol. 2008 August; 4(8): e1000141. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000141.
PMCID: PMC2453326
Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies
Ranyee A. Chiang, Andrej Sali, and Patricia C. Babbitt
PLoS Comput Biol. 2008 August; 4(8): e1000142. Published online 2008 August 1. doi: 10.1371/journal.pcbi.1000142.
PMCID: PMC2453236
Falling towards Forgetfulness: Synaptic Decay Prevents Spontaneous Recovery of Memory
James V. Stone and Peter E. Jupp
PLoS Comput Biol. 2008 August; 4(8): e1000143. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000143.
PMCID: PMC2516185
Retroviral Integration Process in the Human Genome: Is It Really Non-Random? A New Statistical Approach
Alessandro Ambrosi, Claudia Cattoglio, and Clelia Di Serio
PLoS Comput Biol. 2008 August; 4(8): e1000144. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000144.
PMCID: PMC2453317
Intramolecular Cohesion of Coils Mediated by Phenylalanine–Glycine Motifs in the Natively Unfolded Domain of a Nucleoporin
V. V. Krishnan, Edmond Y. Lau, Justin Yamada, Daniel P. Denning, Samir S. Patel, Michael E. Colvin, and Michael F. Rexach
PLoS Comput Biol. 2008 August; 4(8): e1000145. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000145.
PMCID: PMC2475668
Classifying RNA-Binding Proteins Based on Electrostatic Properties
Shula Shazman and Yael Mandel-Gutfreund
PLoS Comput Biol. 2008 August; 4(8): e1000146. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000146.
PMCID: PMC2518515
A General Definition and Nomenclature for Alternative Splicing Events
Michael Sammeth, Sylvain Foissac, and Roderic Guigó
PLoS Comput Biol. 2008 August; 4(8): e1000147. Published online 2008 August 8. doi: 10.1371/journal.pcbi.1000147.
PMCID: PMC2467475
Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP
Marc Turcotte, Wei Tang, and Elliott M. Ross
PLoS Comput Biol. 2008 August; 4(8): e1000148. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000148.
PMCID: PMC2518520
Host Control of Malaria Infections: Constraints on Immune and Erythropoeitic Response Kinetics
Philip G. McQueen and F. Ellis McKenzie
PLoS Comput Biol. 2008 August; 4(8): e1000149. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000149.
PMCID: PMC2491590
Self Containment, a Property of Modular RNA Structures, Distinguishes microRNAs
Miler T. Lee and Junhyong Kim
PLoS Comput Biol. 2008 August; 4(8): e1000150. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000150.
PMCID: PMC2517099
A Novel Three-Phase Model of Brain Tissue Microstructure
Jana L. Gevertz and Salvatore Torquato
PLoS Comput Biol. 2008 August; 4(8): e1000152. Published online 2008 August 15. doi: 10.1371/journal.pcbi.1000152.
PMCID: PMC2495040
Structure and Dynamics of Interphase Chromosomes
Angelo Rosa and Ralf Everaers
PLoS Comput Biol. 2008 August; 4(8): e1000153. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000153.
PMCID: PMC2515109
A Feature-Based Approach to Modeling Protein–DNA Interactions
Eilon Sharon, Shai Lubliner, and Eran Segal
PLoS Comput Biol. 2008 August; 4(8): e1000154. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000154.
PMCID: PMC2516605
The Effect of a ΔK280 Mutation on the Unfolded State of a Microtubule-Binding Repeat in Tau
Austin Huang and Collin M. Stultz
PLoS Comput Biol. 2008 August; 4(8): e1000155. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000155.
PMCID: PMC2494868
PhyloGibbs-MP: Module Prediction and Discriminative Motif-Finding by Gibbs Sampling
Rahul Siddharthan
PLoS Comput Biol. 2008 August; 4(8): e1000156. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000156.
PMCID: PMC2518514
Nonlinear Muscles, Passive Viscoelasticity and Body Taper Conspire To Create Neuromechanical Phase Lags in Anguilliform Swimmers
T. McMillen, T. Williams, and P. Holmes
PLoS Comput Biol. 2008 August; 4(8): e1000157. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000157.
PMCID: PMC2518218
Modeling ChIP Sequencing In Silico with Applications
Zhengdong D. Zhang, Joel Rozowsky, Michael Snyder, Joseph Chang, and Mark Gerstein
PLoS Comput Biol. 2008 August; 4(8): e1000158. Published online 2008 August 22. doi: 10.1371/journal.pcbi.1000158.
PMCID: PMC2507756
Combining Structural Connectivity and Response Latencies to Model the Structure of the Visual System
Michael Capalbo, Eric Postma, and Rainer Goebel
PLoS Comput Biol. 2008 August; 4(8): e1000159. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000159.
PMCID: PMC2507758
Biophysical Parameters Modification Could Overcome Essential Hearing Gaps
A. Kern, C. Heid, W.-H. Steeb, N. Stoop, and R. Stoop
PLoS Comput Biol. 2008 August; 4(8): e1000161. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000161.
PMCID: PMC2516184
Inference of Protein Complex Activities from Chemical-Genetic Profile and Its Applications: Predicting Drug-Target Pathways
Sangjo Han and Dongsup Kim
PLoS Comput Biol. 2008 August; 4(8): e1000162. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000162.
PMCID: PMC2515108
Cooperative Transition between Open and Closed Conformations in Potassium Channels
Turkan Haliloglu and Nir Ben-Tal
PLoS Comput Biol. 2008 August; 4(8): e1000164. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000164.
PMCID: PMC2528004
Network Inference Algorithms Elucidate Nrf2 Regulation of Mouse Lung Oxidative Stress
Ronald C. Taylor, George Acquaah-Mensah, Mudita Singhal, Deepti Malhotra, and Shyam Biswal
PLoS Comput Biol. 2008 August; 4(8): e1000166. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000166.
PMCID: PMC2516606
Noise Reduction by Diffusional Dissipation in a Minimal Quorum Sensing Motif
Yu Tanouchi, Dennis Tu, Jungsang Kim, and Lingchong You
PLoS Comput Biol. 2008 August; 4(8): e1000167. Published online 2008 August 29. doi: 10.1371/journal.pcbi.1000167.
PMCID: PMC2507755
Correction
Correction: Classifying RNA-Binding Proteins Based on Electrostatic Properties
Shula Shazman and Yael Mandel-Gutfreund
PLoS Comput Biol. 2008 August; 4(8): 10.1371/annotation/be4eb7dd-4092-49c1-a619-e8eeba40ed67. Published online 2008 August 21. doi: 10.1371/annotation/be4eb7dd-4092-49c1-a619-e8eeba40ed67.
PMCID: PMC2651598
Corrects: Shula Shazman, et al. Classifying RNA-Binding Proteins Based on Electrostatic Properties. PLoS Comput Biol. 2008 August; 4(8): e1000146.
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