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HIV/AIDS Topics

Natural Science

Contents
In-Depth: General
In-Depth: Clinical Laboratory Methods

In-Depth: General

  • Molecular Insights Into HIV Biology
    Warner C. Greene, MD, PhD, and B. Matija Peterlin, MD
    Reviews current understanding of the HIV life cycle, including interactions between viral proteins and cellular machinery, and highlights promising future points of attack
  • Structure, Expression, and Regulation of the HIV Genome
    Thomas J. Hope, PhD, and Didier Trono, MD
    Reviews the individual viral proteins and their functions, and discusses factors regulating the transcription and processing of viral mRNA

In-Depth: Clinical Laboratory Methods

  • HIV Antibody Assays
    Niel Constantine, PhD
    Focuses on antibody detection, the most widely used and most effective way to identify HIV infection
  • HIV Viral Load Assays
    Teri J. Liegler, PhD, and Robert M. Grant, MD, MPH
    Describes the three most widely used commercial assays, with attention to aspects of each assay that may favor its use in different clinical situations
  • Assays for Antiretroviral Resistance
    Robert W. Shafer, MD
    Covers genotypic and phenotypic resistance testing, drug resistance interpretation, and limitations of testing
  • Assays to Detect Host Immune Responses to HIV
    Helen Horton, PhD, and M. Juliana McElrath, MD, PhD
    Discusses both humoral and cellular immune responses