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National HIV/AIDS Program | | | |
| Natural Science | In-Depth: General | | - Molecular Insights Into HIV Biology
Warner C. Greene, MD, PhD, and B. Matija Peterlin, MD Reviews current understanding of the HIV life cycle, including interactions between viral proteins and cellular machinery, and highlights promising future points of attack
- Structure, Expression, and Regulation of the HIV Genome
Thomas J. Hope, PhD, and Didier Trono, MD Reviews the individual viral proteins and their functions, and discusses factors regulating the transcription and processing of viral mRNA
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| In-Depth: Clinical Laboratory Methods | | - HIV Antibody Assays
Niel Constantine, PhD Focuses on antibody detection, the most widely used and most effective way to identify HIV infection
- HIV Viral Load Assays
Teri J. Liegler, PhD, and Robert M. Grant, MD, MPH Describes the three most widely used commercial assays, with attention to aspects of each assay that may favor its use in different clinical situations
- Assays for Antiretroviral Resistance
Robert W. Shafer, MD Covers genotypic and phenotypic resistance testing, drug resistance interpretation, and limitations of testing
- Assays to Detect Host Immune Responses to HIV
Helen Horton, PhD, and M. Juliana McElrath, MD, PhD Discusses both humoral and cellular immune responses
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Reviewed/Updated Date: October 13, 2008 |
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