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Volume 4(9);  September 2008
Perspective
Chromosome Mechanics and Meiotic Engine Maintenance
Michael E. Dresser
PLoS Genet. 2008 September; 4(9): e1000210. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000210.
PMCID: PMC2533404
Review
A Review of Family-Based Tests for Linkage Disequilibrium between a Quantitative Trait and a Genetic Marker
Warren J. Ewens, Mingyao Li, and Richard S. Spielman
PLoS Genet. 2008 September; 4(9): e1000180. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000180.
PMCID: PMC2528965
Research Articles
Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2
Carlos F. Pereira, Rémi Terranova, Natalie K. Ryan, Joana Santos, Kelly J. Morris, Wei Cui, Matthias Merkenschlager, and Amanda G. Fisher
PLoS Genet. 2008 September; 4(9): e1000170. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000170.
PMCID: PMC2527997
Identification of Neural Crest and Glial Enhancers at the Mouse Sox10 Locus through Transgenesis in Zebrafish
Anthony Antonellis, Jimmy L. Huynh, Shih-Queen Lee-Lin, Ryan M. Vinton, Gabriel Renaud, Stacie K. Loftus, Gene Elliot, Tyra G. Wolfsberg, Eric D. Green, Andrew S. McCallion, and William J. Pavan
PLoS Genet. 2008 September; 4(9): e1000174. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000174.
PMCID: PMC2518861
Segmental Duplications Arise from Pol32-Dependent Repair of Broken Forks through Two Alternative Replication-Based Mechanisms
Celia Payen, Romain Koszul, Bernard Dujon, and Gilles Fischer
PLoS Genet. 2008 September; 4(9): e1000175. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000175.
PMCID: PMC2518615
Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated ELGN2-Mediated Oxygen-Sensing Response
Julie M. Koeman, Ryan C. Russell, Min-Han Tan, David Petillo, Michael Westphal, Katherine Koelzer, Julie L. Metcalf, Zhongfa Zhang, Daisuke Matsuda, Karl J. Dykema, Heather L. Houseman, Eric J. Kort, Laura L. Furge, Richard J. Kahnoski, Stéphane Richard, Annick Vieillefond, Pamela J. Swiatek, Bin Tean Teh, Michael Ohh, and Kyle A. Furge
PLoS Genet. 2008 September; 4(9): e1000176. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000176.
PMCID: PMC2518213
A Sox10 Expression Screen Identifies an Amino Acid Essential for Erbb3 Function
Kristina Buac, Dawn E. Watkins-Chow, Stacie K. Loftus, Denise M. Larson, Arturo Incao, Gretchen Gibney, and William J. Pavan
PLoS Genet. 2008 September; 4(9): e1000177. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000177.
PMCID: PMC2518866
Stability and Dynamics of Polycomb Target Sites in Drosophila Development
Camilla Kwong, Boris Adryan, Ian Bell, Lisa Meadows, Steven Russell, J. Robert Manak, and Robert White
PLoS Genet. 2008 September; 4(9): e1000178. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000178.
PMCID: PMC2525605
Genetic Modifiers of MeCP2 Function in Drosophila
Holly N. Cukier, Alma M. Perez, Ann L. Collins, Zhaolan Zhou, Huda Y. Zoghbi, and Juan Botas
PLoS Genet. 2008 September; 4(9): e1000179. Published online 2008 September 5. doi: 10.1371/journal.pgen.1000179.
PMCID: PMC2518867
Is Mate Choice in Humans MHC-Dependent?
Raphaëlle Chaix, Chen Cao, and Peter Donnelly
PLoS Genet. 2008 September; 4(9): e1000184. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000184.
PMCID: PMC2519788
The Genome of Borrelia recurrentis, the Agent of Deadly Louse-Borne Relapsing Fever, Is a Degraded Subset of Tick-Borne Borrelia duttonii
Magali Lescot, Stéphane Audic, Catherine Robert, Thi Tien Nguyen, Guillaume Blanc, Sally J. Cutler, Patrick Wincker, Arnaud Couloux, Jean-Michel Claverie, Didier Raoult, and Michel Drancourt
PLoS Genet. 2008 September; 4(9): e1000185. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000185.
PMCID: PMC2525819
MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis
J. Kim Holloway, James Booth, Winfried Edelmann, Clare H. McGowan, and Paula E. Cohen
PLoS Genet. 2008 September; 4(9): e1000186. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000186.
PMCID: PMC2525838
The Genomic Distribution and Function of Histone Variant HTZ-1 during C. elegans Embryogenesis
Christina M. Whittle, Karissa N. McClinic, Sevinc Ercan, Xinmin Zhang, Roland D. Green, William G. Kelly, and Jason D. Lieb
PLoS Genet. 2008 September; 4(9): e1000187. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000187.
PMCID: PMC2522285
Csm4, in Collaboration with Ndj1, Mediates Telomere-Led Chromosome Dynamics and Recombination during Yeast Meiosis
Jennifer J. Wanat, Keun P. Kim, Romain Koszul, Sarah Zanders, Beth Weiner, Nancy Kleckner, and Eric Alani
PLoS Genet. 2008 September; 4(9): e1000188. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000188.
PMCID: PMC2533701
Human MLH1 Protein Participates in Genomic Damage Checkpoint Signaling in Response to DNA Interstrand Crosslinks, while MSH2 Functions in DNA Repair
Qi Wu and Karen M. Vasquez
PLoS Genet. 2008 September; 4(9): e1000189. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000189.
PMCID: PMC2526179
The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure
Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A. Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez, Susana Gonzalo, Yi Zhang, En Li, and Taiping Chen
PLoS Genet. 2008 September; 4(9): e1000190. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000190.
PMCID: PMC2527135
Evolution of a New Function by Degenerative Mutation in Cephalochordate Steroid Receptors
Jamie T. Bridgham, Justine E. Brown, Adriana Rodríguez-Marí, Julian M. Catchen, and Joseph W. Thornton
PLoS Genet. 2008 September; 4(9): e1000191. Published online 2008 September 12. doi: 10.1371/journal.pgen.1000191.
PMCID: PMC2527136
A Mouse Model of Harlequin Ichthyosis Delineates a Key Role for Abca12 in Lipid Homeostasis
Ian Smyth, Douglas F. Hacking, Adrienne A. Hilton, Nigora Mukhamedova, Peter J. Meikle, Sarah Ellis, Keith Slattery, Janelle E. Collinge, Carolyn A. de Graaf, Melanie Bahlo, Dmitri Sviridov, Benjamin T. Kile, and Douglas J. Hilton
PLoS Genet. 2008 September; 4(9): e1000192. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000192.
PMCID: PMC2529452
Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
Nicola J. Rutherford, Yong-Jie Zhang, Matt Baker, Jennifer M. Gass, NiCole A. Finch, Ya-Fei Xu, Heather Stewart, Brendan J. Kelley, Karen Kuntz, Richard J. P. Crook, Jemeen Sreedharan, Caroline Vance, Eric Sorenson, Carol Lippa, Eileen H. Bigio, Daniel H. Geschwind, David S. Knopman, Hiroshi Mitsumoto, Ronald C. Petersen, Neil R. Cashman, Mike Hutton, Christopher E. Shaw, Kevin B. Boylan, Bradley Boeve, Neill R. Graff-Radford, Zbigniew K. Wszolek, Richard J. Caselli, Dennis W. Dickson, Ian R. Mackenzie, Leonard Petrucelli, and Rosa Rademakers
PLoS Genet. 2008 September; 4(9): e1000193. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000193.
PMCID: PMC2527686
corona Is Required for Higher-Order Assembly of Transverse Filaments into Full-Length Synaptonemal Complex in Drosophila Oocytes
Scott L. Page, Radhika S. Khetani, Cathleen M. Lake, Rachel J. Nielsen, Jennifer K. Jeffress, William D. Warren, Sharon E. Bickel, and R. Scott Hawley
PLoS Genet. 2008 September; 4(9): e1000194. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000194.
PMCID: PMC2529403
Missense Mutation in Exon 2 of SLC36A1 Responsible for Champagne Dilution in Horses
Deborah Cook, Samantha Brooks, Rebecca Bellone, and Ernest Bailey
PLoS Genet. 2008 September; 4(9): e1000195. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000195.
PMCID: PMC2535566
Csm4-Dependent Telomere Movement on Nuclear Envelope Promotes Meiotic Recombination
Hiromichi Kosaka, Miki Shinohara, and Akira Shinohara
PLoS Genet. 2008 September; 4(9): e1000196. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000196.
PMCID: PMC2533704
Screening and Replication using the Same Data Set: Testing Strategies for Family-Based Studies in which All Probands Are Affected
Amy Murphy, Scott T. Weiss, and Christoph Lange
PLoS Genet. 2008 September; 4(9): e1000197. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000197.
PMCID: PMC2529406
An Approximate Bayesian Estimator Suggests Strong, Recurrent Selective Sweeps in Drosophila
Jeffrey D. Jensen, Kevin R. Thornton, and Peter Andolfatto
PLoS Genet. 2008 September; 4(9): e1000198. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000198.
PMCID: PMC2529407
Deletion of the Pluripotency-Associated Tex19.1 Gene Causes Activation of Endogenous Retroviruses and Defective Spermatogenesis in Mice
Rupert Öllinger, Andrew J. Childs, Hannah M. Burgess, Robert M. Speed, Pia R. Lundegaard, Nicola Reynolds, Nicola K. Gray, Howard J. Cooke, and Ian R. Adams
PLoS Genet. 2008 September; 4(9): e1000199. Published online 2008 September 19. doi: 10.1371/journal.pgen.1000199.
PMCID: PMC2531233
Sex-Specific Genetic Structure and Social Organization in Central Asia: Insights from a Multi-Locus Study
Laure Ségurel, Begoña Martínez-Cruz, Lluis Quintana-Murci, Patricia Balaresque, Myriam Georges, Tatiana Hegay, Almaz Aldashev, Firuza Nasyrova, Mark A. Jobling, Evelyne Heyer, and Renaud Vitalis
PLoS Genet. 2008 September; 4(9): e1000200. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000200.
PMCID: PMC2535577
FtsK-Dependent Dimer Resolution on Multiple Chromosomes in the Pathogen Vibrio cholerae
Marie-Eve Val, Sean P. Kennedy, Meriem El Karoui, Laetitia Bonné, Fabien Chevalier, and François-Xavier Barre
PLoS Genet. 2008 September; 4(9): e1000201. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000201.
PMCID: PMC2533119
Sex-Biased Evolutionary Forces Shape Genomic Patterns of Human Diversity
Michael F. Hammer, Fernando L. Mendez, Murray P. Cox, August E. Woerner, and Jeffrey D. Wall
PLoS Genet. 2008 September; 4(9): e1000202. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000202.
PMCID: PMC2538571
Tracing the Source of Campylobacteriosis
Daniel J. Wilson, Edith Gabriel, Andrew J. H. Leatherbarrow, John Cheesbrough, Steven Gee, Eric Bolton, Andrew Fox, Paul Fearnhead, C. Anthony Hart, and Peter J. Diggle
PLoS Genet. 2008 September; 4(9): e1000203. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000203.
PMCID: PMC2538567
Intronic Alus Influence Alternative Splicing
Galit Lev-Maor, Oren Ram, Eddo Kim, Noa Sela, Amir Goren, Erez Y. Levanon, and Gil Ast
PLoS Genet. 2008 September; 4(9): e1000204. Published online 2008 September 26. doi: 10.1371/journal.pgen.1000204.
PMCID: PMC2533698
Corrections
Correction: WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development
Norimasa Iwanami, Tomokazu Higuchi, Yumi Sasano, Toshinobu Fujiwara, Vu Q. Hoa, Minoru Okada, Sadiqur R. Talukder, Sanae Kunimatsu, Jie Li, Fumi Saito, Chitralekha Bhattacharya, Angabin Matin, Takashi Sasaki, Nobuyoshi Shimizu, Hiroshi Mitani, Heinz Himmelbauer, Akihiro Momoi, Hisato Kondoh, Makoto Furutani-Seiki, and Yousuke Takahama
PLoS Genet. 2008 September; 4(9): 10.1371/annotation/6683988c-4647-4550-88e3-e8ba052f7916. Published online 2008 September 4. doi: 10.1371/annotation/6683988c-4647-4550-88e3-e8ba052f7916.
PMCID: PMC2645275
Corrects: Norimasa Iwanami, et al. WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development. PLoS Genet. 2008 August; 4(8): e1000171.
Correction: Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated EGLN2-Mediated Oxygen-Sensing Response
Julie M. Koeman, Ryan C. Russell, Min-Han Tan, David Petillo, Michael Westphal, Katherine Koelzer, Julie L. Metcalf, Zhongfa Zhang, Daisuke Matsuda, Karl J. Dykema, Heather L. Houseman, Eric J. Kort, Laura L. Furge, Richard J. Kahnoski, Stéphane Richard, Annick Vieillefond, Pamela J. Swiatek, Bin Tean Teh, Michael Ohh, and Kyle A. Furge
PLoS Genet. 2008 September; 4(9): 10.1371/annotation/7f57058f-cc02-45a6-bfab-a835619e3916. Published online 2008 September 18. doi: 10.1371/annotation/7f57058f-cc02-45a6-bfab-a835619e3916.
PMCID: PMC2648618
Corrects: Julie M. Koeman, et al. Somatic Pairing of Chromosome 19 in Renal Oncocytoma Is Associated with Deregulated ELGN2-Mediated Oxygen-Sensing Response. PLoS Genet. 2008 September; 4(9): e1000176.
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