| | This journal provides immediate access to some articles. Perspective A Tribute to Evgenii V. Ananiev, 1947–2008 Sergei M. Mirkin PMCID: PMC2478716 Rise of the Machines David Gresham and Leonid Kruglyak PMCID: PMC2467494 Interview Sweating the Details: An Interview with Jamie Thomson Jane Gitschier PMCID: PMC2517851 Research Articles Genic and Global Functions for Paf1C in Chromatin Modification and Gene Expression in Arabidopsis Sookyung Oh, Sunchung Park, and Steven van Nocker PMCID: PMC2515192 High-Precision, Whole-Genome Sequencing of Laboratory Strains Facilitates Genetic Studies Anjana Srivatsan, Yi Han, Jianlan Peng, Ashley K. Tehranchi, Richard Gibbs, Jue D. Wang, and Rui Chen PMCID: PMC2474695 Efficient Genetic Method for Establishing Drosophila Cell Lines Unlocks the Potential to Create Lines of Specific Genotypes Amanda Simcox, Sayan Mitra, Sharon Truesdell, Litty Paul, Ting Chen, Jonathan P. Butchar, and Steven Justiniano PMCID: PMC2474701 FHY1 Mediates Nuclear Import of the Light-Activated Phytochrome A Photoreceptor Thierry Genoud, Fabian Schweizer, Anke Tscheuschler, Dimitry Debrieux, Jorge J. Casal, Eberhard Schäfer, Andreas Hiltbrunner, and Christian Fankhauser PMCID: PMC2483295 Patterns of Positive Selection in Six Mammalian Genomes Carolin Kosiol, Tomáš Vinař, Rute R. da Fonseca, Melissa J. Hubisz, Carlos D. Bustamante, Rasmus Nielsen, and Adam Siepel PMCID: PMC2483296 Antagonism between DNA and H3K27 Methylation at the Imprinted Rasgrf1 Locus Anders M. Lindroth, Yoon Jung Park, Chelsea M. McLean, Gregoriy A. Dokshin, Jenna M. Persson, Herry Herman, Diego Pasini, Xavier Miró, Mary E. Donohoe, Jeannie T. Lee, Kristian Helin, and Paul D. Soloway PMCID: PMC2475503 Unveiling Novel RecO Distant Orthologues Involved in Homologous Recombination Stéphanie Marsin, Aurélie Mathieu, Thierry Kortulewski, Raphaël Guérois, and J. Pablo Radicella PMCID: PMC2475510 Linkage Disequilibrium-Based Quality Control for Large-Scale Genetic Studies Paul Scheet and Matthew Stephens PMCID: PMC2475504 Evolutionary Convergence on Highly-Conserved 3′ Intron Structures in Intron-Poor Eukaryotes and Insights into the Ancestral Eukaryotic Genome Manuel Irimia and Scott William Roy PMCID: PMC2483917 High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock Anatole Ghazalpour, Sudheer Doss, Hyun Kang, Charles Farber, Ping-Zi Wen, Alec Brozell, Ruth Castellanos, Eleazar Eskin, Desmond J. Smith, Thomas A. Drake, and Aldons J. Lusis PMCID: PMC2483929 Mitochondrial Targeting Adaptation of the Hominoid-Specific Glutamate Dehydrogenase Driven by Positive Darwinian Selection Lia Rosso, Ana C. Marques, Andreas S. Reichert, and Henrik Kaessmann PMCID: PMC2478720 Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast Elke Ericson, Marinella Gebbia, Lawrence E. Heisler, Jan Wildenhain, Mike Tyers, Guri Giaever, and Corey Nislow PMCID: PMC2483942 The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers Shuji Kishi, Peter E. Bayliss, Junzo Uchiyama, Eriko Koshimizu, Jie Qi, Purushothama Nanjappa, Shintaro Imamura, Asiful Islam, Donna Neuberg, Adam Amsterdam, and Thomas M. Roberts PMCID: PMC2515337 E2F and p53 Induce Apoptosis Independently during Drosophila Development but Intersect in the Context of DNA Damage Nam-Sung Moon, Luisa Di Stefano, Erick J. Morris, Reena Patel, Kristin White, and Nicholas J. Dyson PMCID: PMC2491587 Genetic Evidence of Serum Phosphate-Independent Functions of FGF-23 on Bone Despina Sitara, Somi Kim, Mohammed S. Razzaque, Clemens Bergwitz, Takashi Taguchi, Christiane Schüler, Reinhold G. Erben, and Beate Lanske PMCID: PMC2483943 Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island Heather M. O'Hagan, Helai P. Mohammad, and Stephen B. Baylin PMCID: PMC2491723 Three SRA-Domain Methylcytosine-Binding Proteins Cooperate to Maintain Global CpG Methylation and Epigenetic Silencing in Arabidopsis Hye Ryun Woo, Travis A. Dittmer, and Eric J. Richards PMCID: PMC2491724 Selective Constraints in Experimentally Defined Primate Regulatory Regions Daniel J. Gaffney, Ran Blekhman, and Jacek Majewski PMCID: PMC2490716 Mutant Screen Distinguishes between Residues Necessary for Light-Signal Perception and Signal Transfer by Phytochrome B Yoshito Oka, Tomonao Matsushita, Nobuyoshi Mochizuki, Peter H. Quail, and Akira Nagatani PMCID: PMC2494609 Context Differences Reveal Insulator and Activator Functions of a Su(Hw) Binding Region Alexey A. Soshnev, Xingguo Li, Misty D. Wehling, and Pamela K. Geyer PMCID: PMC2493044 Genetic Variation in an Individual Human Exome Pauline C. Ng, Samuel Levy, Jiaqi Huang, Timothy B. Stockwell, Brian P. Walenz, Kelvin Li, Nelson Axelrod, Dana A. Busam, Robert L. Strausberg, and J. Craig Venter PMCID: PMC2493042 Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms Björn Schumacher, Ingrid van der Pluijm, Michael J. Moorhouse, Theodore Kosteas, Andria Rasile Robinson, Yousin Suh, Timo M. Breit, Harry van Steeg, Laura J. Niedernhofer, Wilfred van IJcken, Andrzej Bartke, Stephen R. Spindler, Jan H. J. Hoeijmakers, Gijsbertus T. J. van der Horst, and George A. Garinis PMCID: PMC2493043 An Sp1/Sp3 Binding Polymorphism Confers Methylation Protection Yanis A. Boumber, Yutaka Kondo, Xuqi Chen, Lanlan Shen, Yi Guo, Carmen Tellez, Marcos R. H. Estécio, Saira Ahmed, and Jean-Pierre J. Issa PMCID: PMC2515197 Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq Alexandra Sittka, Sacha Lucchini, Kai Papenfort, Cynthia M. Sharma, Katarzyna Rolle, Tim T. Binnewies, Jay C. D. Hinton, and Jörg Vogel PMCID: PMC2515195 Identification and Functional Analysis of Light-Responsive Unique Genes and Gene Family Members in Rice Ki-Hong Jung, Jinwon Lee, Chris Dardick, Young-Su Seo, Peijian Cao, Patrick Canlas, Jirapa Phetsom, Xia Xu, Shu Ouyang, Kyungsook An, Yun-Ja Cho, Geun-Cheol Lee, Yoosook Lee, Gynheung An, and Pamela C. Ronald PMCID: PMC2515340 Divergent Evolution of CHD3 Proteins Resulted in MOM1 Refining Epigenetic Control in Vascular Plants Marian Čaikovski, Chotika Yokthongwattana, Yoshiki Habu, Taisuke Nishimura, Olivier Mathieu, and Jerzy Paszkowski PMCID: PMC2507757 Genome-Wide Scan on Total Serum IgE Levels Identifies FCER1A as Novel Susceptibility Locus Stephan Weidinger, Christian Gieger, Elke Rodriguez, Hansjörg Baurecht, Martin Mempel, Norman Klopp, Henning Gohlke, Stefan Wagenpfeil, Markus Ollert, Johannes Ring, Heidrun Behrendt, Joachim Heinrich, Natalija Novak, Thomas Bieber, Ursula Krämer, Dietrich Berdel, Andrea von Berg, Carl Peter Bauer, Olf Herbarth, Sibylle Koletzko, Holger Prokisch, Divya Mehta, Thomas Meitinger, Martin Depner, Erika von Mutius, Liming Liang, Miriam Moffatt, William Cookson, Michael Kabesch, H.-Erich Wichmann, and Thomas Illig PMCID: PMC2565692 Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays Nils Homer, Szabolcs Szelinger, Margot Redman, David Duggan, Waibhav Tembe, Jill Muehling, John V. Pearson, Dietrich A. Stephan, Stanley F. Nelson, and David W. Craig PMCID: PMC2516199 Repeated Adaptive Introgression at a Gene under Multiallelic Balancing Selection Vincent Castric, Jesper Bechsgaard, Mikkel H. Schierup, and Xavier Vekemans PMCID: PMC2517234 The Evolution of Epigenetic Regulators CTCF and BORIS/CTCFL in Amniotes Timothy A. Hore, Janine E. Deakin, and Jennifer A. Marshall Graves PMCID: PMC2515639 WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development Norimasa Iwanami, Tomokazu Higuchi, Yumi Sasano, Toshinobu Fujiwara, Vu Q. Hoa, Minoru Okada, Sadiqur R. Talukder, Sanae Kunimatsu, Jie Li, Fumi Saito, Chitralekha Bhattacharya, Angabin Matin, Takashi Sasaki, Nobuyoshi Shimizu, Hiroshi Mitani, Heinz Himmelbauer, Akihiro Momoi, Hisato Kondoh, Makoto Furutani-Seiki, and Yousuke Takahama PMCID: PMC2515640 Analysis of Transposon Interruptions Suggests Selection for L1 Elements on the X Chromosome György Abrusán, Joti Giordano, and Peter E. Warburton PMCID: PMC2517846 The Challenge of Regulation in a Minimal Photoautotroph: Non-Coding RNAs in Prochlorococcus Claudia Steglich, Matthias E. Futschik, Debbie Lindell, Bjoern Voss, Sallie W. Chisholm, and Wolfgang R. Hess PMCID: PMC2518516 C. elegans Nucleostemin Is Required for Larval Growth and Germline Stem Cell Division Michelle M. Kudron and Valerie Reinke PMCID: PMC2515194 A Catalog of Neutral and Deleterious Polymorphism in Yeast Scott W. Doniger, Hyun Seok Kim, Devjanee Swain, Daniella Corcuera, Morgan Williams, Shiaw-Pyng Yang, and Justin C. Fay PMCID: PMC2515631 |
