| | This journal provides immediate access to some articles. Editorial PLoS Genetics Turns Three: Looking Back, Looking Ahead Wayne N. Frankel and Gregory S. Barsh PMCID: PMC2444048 Interview Stable in a Genome of Instability: An Interview with Evan Eichler Jane Gitschier PMCID: PMC2442658 Review Pain Genes Tom Foulkes and John N. Wood PMCID: PMC2432024 Research Articles Identification of Neural Outgrowth Genes using Genome-Wide RNAi Katharine J. Sepp, Pengyu Hong, Sofia B. Lizarraga, Judy S. Liu, Luis A. Mejia, Christopher A. Walsh, and Norbert Perrimon PMCID: PMC2435276 Genetic Interactions of MAF1 Identify a Role for Med20 in Transcriptional Repression of Ribosomal Protein Genes Ian M. Willis, Gordon Chua, Amy H. Tong, Renee L. Brost, Timothy R. Hughes, Charles Boone, and Robyn D. Moir PMCID: PMC2435279 Pervasive and Persistent Redundancy among Duplicated Genes in Yeast E. Jedediah Dean, Jerel C. Davis, Ronald W. Davis, and Dmitri A. Petrov PMCID: PMC2440806 Tracing Sub-Structure in the European American Population with PCA-Informative Markers Peristera Paschou, Petros Drineas, Jamey Lewis, Caroline M. Nievergelt, Deborah A. Nickerson, Joshua D. Smith, Paul M. Ridker, Daniel I. Chasman, Ronald M. Krauss, and Elad Ziv PMCID: PMC2537989 An Integrated Approach for the Analysis of Biological Pathways using Mixed Models Lily Wang, Bing Zhang, Russell D. Wolfinger, and Xi Chen PMCID: PMC2565842 Sensory Perception of Food and Insulin-Like Signals Influence Seizure Susceptibility Todd R. Gruninger, Daisy G. Gualberto, and L. Rene Garcia PMCID: PMC2432499 Novel Association of ABO Histo-Blood Group Antigen with Soluble ICAM-1: Results of a Genome-Wide Association Study of 6,578 Women Guillaume Paré, Daniel I. Chasman, Mark Kellogg, Robert Y. L. Zee, Nader Rifai, Sunita Badola, Joseph P. Miletich, and Paul M. Ridker PMCID: PMC2432033 The Recombinational Anatomy of a Mouse Chromosome Kenneth Paigen, Jin P. Szatkiewicz, Kathryn Sawyer, Nicole Leahy, Emil D. Parvanov, Siemon H. S. Ng, Joel H. Graber, Karl W. Broman, and Petko M. Petkov PMCID: PMC2440539 Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae Wei Niu, Zhihua Li, Wenjing Zhan, Vishwanath R. Iyer, and Edward M. Marcotte PMCID: PMC2438615 Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology Siew Hong Lam, Sinnakarupan Mathavan, Yan Tong, Haixia Li, R. Krishna Murthy Karuturi, Yilian Wu, Vinsensius B. Vega, Edison T. Liu, and Zhiyuan Gong PMCID: PMC2442223 Identification and Dissection of a Complex DNA Repair Sensitivity Phenotype in Baker's Yeast Ann Demogines, Erin Smith, Leonid Kruglyak, and Eric Alani PMCID: PMC2440805 A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction Robert B. Weiss, Timothy B. Baker, Dale S. Cannon, Andrew von Niederhausern, Diane M. Dunn, Nori Matsunami, Nanda A. Singh, Lisa Baird, Hilary Coon, William M. McMahon, Megan E. Piper, Michael C. Fiore, Mary Beth Scholand, John E. Connett, Richard E. Kanner, Lorise C. Gahring, Scott W. Rogers, John R. Hoidal, and Mark F. Leppert PMCID: PMC2442220 Identification of Drosophila Mitotic Genes by Combining Co-Expression Analysis and RNA Interference Maria Patrizia Somma, Francesca Ceprani, Elisabetta Bucciarelli, Valeria Naim, Valeria De Arcangelis, Roberto Piergentili, Antonella Palena, Laura Ciapponi, Maria Grazia Giansanti, Claudia Pellacani, Romano Petrucci, Giovanni Cenci, Fiammetta Vernì, Barbara Fasulo, Michael L. Goldberg, Ferdinando Di Cunto, and Maurizio Gatti PMCID: PMC2537813 Genome-Wide Expression Patterns and the Genetic Architecture of a Fundamental Social Trait John Wang, Kenneth G. Ross, and Laurent Keller PMCID: PMC2442221 Dynamics of Genome Rearrangement in Bacterial Populations Aaron E. Darling, István Miklós, and Mark A. Ragan PMCID: PMC2483231 A Precisely Regulated Gene Expression Cassette Potently Modulates Metastasis and Survival in Multiple Solid Cancers Kun Yu, Kumaresan Ganesan, Lay Keng Tan, Mirtha Laban, Jeanie Wu, Xiao Dong Zhao, Hongmin Li, Carol Ho Wing Leung, Yansong Zhu, Chia Lin Wei, Shing Chuan Hooi, Lance Miller, and Patrick Tan PMCID: PMC2444049 Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies Clive J. Hoggart, John C. Whittaker, Maria De Iorio, and David J. Balding PMCID: PMC2464715 E1 Ubiquitin-Activating Enzyme UBA-1 Plays Multiple Roles throughout C. elegans Development Madhura Kulkarni and Harold E. Smith PMCID: PMC2443343 Myc Oncogene-Induced Genomic Instability: DNA Palindromes in Bursal Lymphomagenesis Paul E. Neiman, Katrina Elsaesser, Gilbert Loring, and Robert Kimmel PMCID: PMC2444050 Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes Brian D. Reed, Alexandra E. Charos, Anna M. Szekely, Sherman M. Weissman, and Michael Snyder PMCID: PMC2478640 Regulation of Zebrafish Skeletogenesis by ext2/dackel and papst1/pinscher Aurélie Clément, Malgorzata Wiweger, Sophia von der Hardt, Melissa A. Rusch, Scott B. Selleck, Chi-Bin Chien, and Henry H. Roehl PMCID: PMC2453328 Positional Cloning of “Lisch-like”, a Candidate Modifier of Susceptibility to Type 2 Diabetes in Mice Marija Dokmanovic-Chouinard, Wendy K. Chung, Jean-Claude Chevre, Elizabeth Watson, Jason Yonan, Beebe Wiegand, Yana Bromberg, Nao Wakae, Chris V. Wright, John Overton, Sujoy Ghosh, Ganesh M. Sathe, Carina E. Ammala, Kathleen K. Brown, Rokuro Ito, Charles LeDuc, Keely Solomon, Stuart G. Fischer, and Rudolph L. Leibel PMCID: PMC2464733 The Insulator Binding Protein CTCF Positions 20 Nucleosomes around Its Binding Sites across the Human Genome Yutao Fu, Manisha Sinha, Craig L. Peterson, and Zhiping Weng PMCID: PMC2453330 The Status of Dosage Compensation in the Multiple X Chromosomes of the Platypus Janine E. Deakin, Timothy A. Hore, Edda Koina, and Jennifer A. Marshall Graves PMCID: PMC2453332 Complete Genome Sequence of the N2-Fixing Broad Host Range Endophyte Klebsiella pneumoniae 342 and Virulence Predictions Verified in Mice Derrick E. Fouts, Heather L. Tyler, Robert T. DeBoy, Sean Daugherty, Qinghu Ren, Jonathan H. Badger, Anthony S. Durkin, Heather Huot, Susmita Shrivastava, Sagar Kothari, Robert J. Dodson, Yasmin Mohamoud, Hoda Khouri, Luiz F. W. Roesch, Karen A. Krogfelt, Carsten Struve, Eric W. Triplett, and Barbara A. Methé PMCID: PMC2453333 Corrections Correction: Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling Christine T. Ferrara, Ping Wang, Elias Chaibub Neto, Robert D. Stevens, James R. Bain, Brett R. Wenner, Olga R. Ilkayeva, Mark P. Keller, Daniel A. Blasiole, Christina Kendziorski, Brian S. Yandell, Christopher B. Newgard, and Alan D. Attie PMCID: PMC2648617 Corrects: Christine T. Ferrara, et al. Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling. PLoS Genet. 2008 March; 4(3): e1000034. Correction: Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53 Jennifer J. Jordan, Daniel Menendez, Alberto Inga, Maher Noureddine, Douglas A. Bell, and Michael A. Resnick PMCID: PMC2648616 Corrects: Jennifer J. Jordan, et al. Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53. PLoS Genet. 2008 June; 4(6): e1000104. Correction: The Inexorable Spread of a Newly Arisen Neo-Y Chromosome Paris Veltsos, Irene Keller, and Richard A. Nichols PMCID: PMC2655752 Corrects: Paris Veltsos, et al. The Inexorable Spread of a Newly Arisen Neo-Y Chromosome. PLoS Genet. 2008 May; 4(5): e1000082. |
