Projects

AVIAN GENOMIC AND IMMUNOLOGIC APPROACHES FOR CONTROLLING MUCOSAL PATHOGENS Appropriated (D)   Accession Number: 413057

MOLECULAR AND CELLULAR MECHANISMS OF INNATE IMMUNITY TO THE INTESTINAL PATHOGENS EIMERIA AND SALMONELLA Reimbursable (R)   Accession Number: 408676

AVIAN INTESTINAL MICROARRAY ANALYSIS Reimbursable (R)   Accession Number: 411226

AVIAN GENOMIC AND IMMUNOLOGIC APPROACHES FOR CONTROLLING MUCOSAL PATHOGENS Reimbursable (R)   Accession Number: 413106

UNITED STATES IMMUNE REAGENT NETWORK Reimbursable (R)   Accession Number: 410128

IDENTIFICATION OF PROTECTIVE INNATE IMMUNE MECHANISMS IN COCCIDIOSIS AND SALMONELLOSIS Specific Cooperative Agreement (S)   Accession Number: 409029

RECOMBINANT VACCINATION STRATEGY USING IN OVO INJECTION Trust (T)   Accession Number: 412680

EVALUATION OF NOVEL ADJUVANT ON EIMERIA Trust (T)   Accession Number: 412107

EVALUATION OF NOVEL ADJUVANT IN RECOMBINANT POULTRY VACCINE Trust (T)   Accession Number: 412108

RECOMBINENT DNA VACCINE EVALUATION Trust (T)   Accession Number: 411684

THE DEVELOPMENT OF HYPERIMMUNED IMMUNOGLOBULIN FOR THE CONTROL OF COCCIDIOSIS Trust (T)   Accession Number: 411079

IN VITRO TESTING OF IMMUNOSTIMULATING PLANT EXTRACTS Trust (T)   Accession Number: 412301

STUDY OF THE IMMUNE POTENTIAL OF VARIOUS STRUCTURES OF PARASITES PHASES Trust (T)   Accession Number: 412981

DNA VACCINE TECHNOLOGY Trust (T)   Accession Number: 411642

FUNCTIONAL GENOMICS FOR DIETARY IMMUNOMODULATION Trust (T)   Accession Number: 413513

DEVELOPMENT OF FUNCTIONAL GENOMIC AND IMMUNOLOGIC APPROACHES TO CONTROL AVIAN MUCOSAL PATHOGENS Trust (T)   Accession Number: 412977

Publications

SALMONELLA ENTERICA SEROVAR ENTERITIDIS INFECTION MODULATES DIVERSE FUNCTIONAL PROCESSES OF CHICKEN MACROPHAGE AT THE TRANSCRIPTIONAL LEVEL - (Peer Reviewed Journal) - (10-Sep-08)

QUANTITATIVE GENETIC AND FUNCTIONAL GENOMICS APPROACHES TO INVESTIGATING PARASITE DISEASE RESISTANCE AND PROTECTIVE IMMUNE MECHANISMS IN AVIAN COCCIDIOSIS - (Peer Reviewed Journal)

Lillehoj, H.S., Hong, Y.H., Kim, C. 2008. Quantitative genetic and functional genomics approaches to investigating parasite disease resistance and protective immune mechanisms in avian coccidiosis. Developmental Biology.132:67-76.

INFLUENCE OF PEDIOCOCCUS-BASED PROBIOTIC ON COCCIDIOSIS IN BROILER CHICKENS - (Peer Reviewed Journal)

Lee, S., Lillehoj, H.S., Dalloul, R., Park, D., Hong, Y. 2008. Influence of pediococcus-based probiotic on coccidiosis in broiler chickens. Poultry Science. 86:63-66.

IMMUNOMODULATORY EFFECTS OF ORIENTAL PLUM (PRUNUS SALICINA LINDL.) - (Peer Reviewed Journal)

Lee, S., Lillehoj, H.S., Cho, S., Chun, H., Park, H., Lim, C., Lillehoj, E.P. 2008. Immunomodulatory effects of oriental plum (prunus salicina lindl.). Clinical Immunology. http://www.ncbi.nlm.nih.gov/pubmed/18262269.

DIFFERENTIAL GENE EXPRESSION PROFILES IN TWO B-COMPLEX DISPARATE FAYOUMI CHICKEN LINES FOLLOWING EIMERIA MAXIMA INFECTION - (Abstract) - (22-Aug-08)

MOLECULAR AND FUNCTIONAL CHARACTERIZATIONS OF IL-17 - (Abstract) - (22-Aug-08)

IMMUNOSTIMULATORY AND ANTI-TUMOR EFFECTS OF PLANT EXTRACTS DEMONSTRATED BY IN VITRO CULTURE SYSTEMS - (Abstract)

Lee, S., Lillehoj, H.S., Hong, Y.H., Jang, S., Ionescu, C., Bravo, D. 2008. Immunostimulatory and anti-tumor effects of plant extracts demonstrated by in vitro culture systems. Poultry Science Assoc. meeting held July 19, 2008, Niagara Falls, Canada.

CLONING AND FUNCTIONAL CHARACTERIZATION OF CHICKEN INTERLEUKIN-17D - (Peer Reviewed Journal)

Hong, Y.H., Lillehoj, H.S., Park, D., Lee, S., Han, J., Shin, J., Park, M., Kim, J. 2008. Cloning and functional characterization of chicken interleukin-17d. Veterinary Immunology and Immunopathology. http://www.ncbi.nlm.nih.gov/pubmed/18649949.

DIFFERENTIAL IMMUNE-RELATED GENE EXPRESSION IN TWO GENETICALLY DISPARATE CHICKEN LINES DURING INFECTION BY EIMERIA MAXIMA - (Peer Reviewed Journal) - (01-Aug-08)

NITRIC OXIDE PRODUCTION AND iNOS mRNA EXPRESSION IN IFN-8-STIMULATED CHICKEN MACROPHAGES TRANSFECTED WITH iNOS siRNAs - (Abstract)

Cheeseman, J.H., Lillehoj, H.S., Lamont, S.J. 2008. Nitric oxide production and inos mrna expression in ifn-8-stimulated chicken macrophages transfected with inos sirnas. Avian Immunology Group Meeting held June 234-27, 2008, Brisbane, Australia.

GENE EXPRESSION PROFILES OF TWO B-COMPLEX DISPARATE, GENETICALLY INBRED FAYOUMI CHICKEN LINES THAT DIFFER IN SUSCEPTIBILITY TO EIMERIA MAXIMA - (Peer Reviewed Journal) - (23-Jul-08)

ACUTE PHASE IMMUNE GENE PROFILING OF SPLEEN AND PEYER¿S PATCH IN NAÏVE AND VACCINATED CHICKENS FOLLOWING AVIAN INFLUENZA A (H5N1) VIRUS INFECTION - (Abstract) - (23-Jul-08)

COMPARISON OF TRANSCRIPTIONAL RESPONSES FROM AVIAN GUT TISSUES AFTER E. ACERVULINA AND E. MAXIMA INFECTIONS USING cDNA MICROARRAY TECHNOLOGY - (Peer Reviewed Journal)

Kim, C.H., Lillehoj, H.S., Keeler, C.L. 2008. Comparison of transcriptional responses from avian gut tissues after E. acervulina and E. maxima infections using cdna microarray technology. Developmental Biology. 132:131-140.

TRANSCRIPTIONAL RESPONSE OF CHICKEN MACROPHAGES TO SALMONELLA ENTERICA SEROVAR ENTERITIDIS INFECTION - (Peer Reviewed Journal)

Zhang, S., Lillehoj, H.S., Kim, C., Keeler, C.L., Babu, U., Zhang, M. 2008. Transcriptional response of chicken macrophages to salmonella enterica serovar enteritidis infection. Developmental Biology. 132:153-160.

IMMUNOGENOMIC APPROACHES TO STUDY HOST IMMUNITY TO ENTERIC PATHOGENS - (Peer Reviewed Journal)

Lillehoj, H.S., Kim, C., Keeler, C.L., Zhang, S. 2008. Immunogenomic approaches to study host immunity to enteric pathogens. Poultry Science. 86:1491-1500.

REDUCED NITRIC OXIDE PRODUCTION AND INOS MRNA EXPRESSION IN IFN-G STIMULATED CHICKEN MACROPHAGES TRANSFECTED WITH INOS SIRNAS - (Peer Reviewed Journal)

Cheeseman, J.H., Lillehoj, H.S., Lamont, S.J. 2008. Reduced nitric oxide production and INOS mrna expression in ifn-g stimulated chicken macrophages transfected with inos sirnas. Veterinary Immunology and Immunopathology. 125:375-80.

ISOLATION OF CHICKEN FOLLICULAR DENDRITIC CELLS - (Peer Reviewed Journal)

Lillehoj, H.S., Del Cacho, E., Gallego, M., Lopez-Bernard, F., Sanchez-Acedo, C. 2008. Isolation of chicken follicular dendritic cells. Journal of Immunological Methods. 334:59-69.

IMMUNE-RELATED GENE EXPRESSION IN TWO GENETICALLY DISPARATE FAYOUMI CHICKEN LINES FOLLOWING EIMERIA MAXIMA INFECTION - (Peer Reviewed Journal)

Kim, D., Lillehoj, H.S., Hong, Y.H., Park, D., Lamont, S.J., Han, J., Lillehoj, E.P. 2008. Immune-related gene expression in two genetically disparate fayoumi chicken lines following eimeria maxima infection. International Journal of Poultry Science. 87:433-443.

IDENTIFICATION OF FLOTILLIN-1 ON EIMERIA TENELLA SPOROZOITES AND ITS ROLE IN HOST CELL INVASION - (Peer Reviewed Journal)

Del Cacho, E., Gallego, M., Sanchez-Acedo, C., Lillehoj, H.S. 2008. Identification of flotillin-1 on eimeria tenella sporozoites and its role in host cell invasion. Journal of Parasitology. 93:328-332.

U. S. VETERINARY IMMUNE REAGENTS NETWORK: PROGRESS WITH POULTRY IMMUNE REAGENTS - (Abstract)

Lillehoj, H.S., Hong, Y.H. 2008. U. s. veterinary immune reagents network: progress with poultry immune reagents. Proceedings of Avian Immunology Research Group meeting, June 24-27. Brishane, Australia.

Construction and Application of an Avian Intestinal Intraepithelial Lymphocyte cDNA Microarray for Gene Expression Profiling during Eimeria maxima Infection - (Peer Reviewed Journal)

Kim, Chul, H., Lillehoj, H.S., Bliss, T.W., Keeler, C.L., Hong, Y.H., Park, Dong, W., Yamage, M., Lillehoj, E.P., Min, W. 2008. Construction and Application of an Avian Intestinal Intraepithelial Lymphocyte cDNA Microarray for Gene Expression Profiling during Eimeria maxima Infection. Molecular Immunology. 124:341-354.

ACUTE PHASE IMMUNE GENE PROFILING OF SPLEEN AND PEYER¿S PATCH IN NAÏVE AND VACCINATED CHICKENS FOLLOWING AVIAN INFLUENZA A (H5N1) VIRUS INFECTION - (Abstract)

Kim, C., Lillehoj, H.S., Hong, Y.H., Kim, D., Kapczynski, D.R., Keeler, C.L. 2008. Acute phase immune gene profiling of spleen and peyer¿s patch in naïve and vaccinated chickens following avian influenza a (h5n1) virus infection. 11th Annual Conf. on Vaccine Research, Baltimore, MD.

Identification and characterization of a serpin from Emeria acervulina - (Peer Reviewed Journal)

Fetterer, R.H., Miska, K.B., Jenkins, M.C., Barfield, R.C., Lillehoj, H.S. 2008. Identification and characterization of a serpin from Emeria acervulina. Journal of Parasitology. http://lib.bioinfo.pl/pmid:18576851.

IMMUNOSTIMULATORY PROPERTIES OF DIETARY PLUM (PRUNUS SALICINA LINDL.) ON COCCIDIOSIS - (Abstract)

Lee, S., Lillehoj, H.S., Hong, Y.H., Park, D., Jang, S. 2008. Immunostimulatory properties of dietary plum (prunus salicina lindl.) on coccidiosis. BARC Poster Day. Beltsville, Md. P 26.

NOVEL ANTI-MICROBIAL PEPTIDE, NK-LYSIN, IS PRODUCED LOCALLY IN THE GUT OF EIMERIA-INFECTED HOST - (Abstract)

Hong, Y.H., Lillehoj, H.S., Siragusa, G.R., Bannerman, D.D. 2008. Novel anti-microbial peptide, nk-lysin, is produced locally in the gut of eimeria-infected host. BARC Poster Day.April 23, Beltsville, MD. P 18.

DIFFERENTIAL IMMUNE-RELATED GENE EXPRESSION IN TWO GENETICALLY DISPARATE FAYOUMI CHICKEN LINES FOLLOWING EIMERIA MAXIMA INFECTION - (Abstract)

Kim, D., Lillehoj, H.S., Hong, Y.H., Lamont, S.J. 2008. Differential immune-related gene expression in two genetically disparate fayoumi chicken lines following eimeria maxima infection. BARC Poster Day. April 23. Beltsville, Md. P 23.

IMPROVING POULTRY INNATE IMMUNITY THROUGH NOVEL IMMUNOLOGICAL AND GENOMICS STRATEGIES - (Proceedings/Symposium)

Lillehoj, H.S. 2008. Improving poultry innate immunity through novel immunological and genomics strategies. Latin American Poultry Congress, Sept. 25-28, 2007, Porte Allegro, Brazil. p. 53-72.

Characterization of monoclonal antibodies that recognize the Eimeria tenella microneme protein MIC2 - (Peer Reviewed Journal)

Sasai, K., Fetterer, R.H., Lillehoj, H.S., Matsuura, S., Constantinoiu, C.C., Matsubayashi, M., Hiroyuki, T., Eiichirok, B. 2008. Characterization of monoclonal antibodies that recognize the Eimeria tenella microneme protein MIC2. Jrnl. of Parasitology. Available: http://www.ncbi.nlm.nih.gov/sites/entrez PMID: 18576850.

HOST INNATE IMMUNITY AGAINST INTESTINAL PARASITES - (Review Article)

Lillehoj, H.S. 2007. Host innate immunity against intestinal parasites. Journal of Korean Poultry Science. 34:77-83.

U.S. VETERINARY IMMUNE REAGENTS NETWORK: PROGRESS WITH POULTRY IMMUNE REAGENTS - (Abstract)

Lillehoj, H.S., Hong, Y. 2007. U.S. Veterinary Immune Reagents Network: progress with poultry immune reagents. [abstract]. Research Workers in Animal Diseases Conference, Chicago, IL, 12/02-04/2007.

Immunomodulatory effect of dietary Safflower leaf on coccidiosis - (Peer Reviewed Journal)

Lee, S., Lillehoj, H.S., Heckert, R.A., Cho, S., Hong, Y.H., Park, D., Lillehoj, E.P., Chun, H., Park, H. 2007. Immunomodulatory effect of dietary Safflower leaf on coccidiosis. 18:715-724.

SALMONELLA ENTERITIDIS-INDUCED ALTERATION OF INFLAMMATORY CXCL CHEMOKINE MESSENGER-RNA EXPRESSION AND HISTOLOGIC CHANGES IN THE CECA OF INFECTED CHICKS. - (Peer Reviewed Journal)

Cheeseman, J.H., Levy, N.A., Kaiser, P., Lillehoj, H.S., Lamont, S.J. 2008. SALMONELLA ENTERITIDIS-INDUCED ALTERATION OF INFLAMMATORY CXCL CHEMOKINE MESSENGER-RNA EXPRESSION AND HISTOLOGIC CHANGES IN THE CECA OF INFECTED CHICKS. AVIAN DISASES. 52: 229-34.

Probiotics as an alternative control strategy against avian coccidiosis Probiotics as an alternative control strategy against avian coccidiosis - (Other)

Lillehoj, H.S., Lee, S.H. 2007. Probiotics as an alternative control strategy against avian coccidiosis. Feedinfo News Service Scientific Reviews. Septmeber. Probiotics as an alternative control strategy against avian coccidiosis . Feedinfo News Service.

Dietary modulation of intestinal innate immunity using plant-derived phytochemicals - (Other)

Lillehoj, H.S., Lee, S.H. 2007. Dietary modulation of intestinal innate immunity using plant-derived phytochemicals. Feedinfo News Service Scientific Reviews, September. . Feedinfo News Service.

Improving poultry innate immunity through novel immunological and genomics strategies - (Abstract)

Lillehoj, H.S. 2007. Improving poultry innate immunity through novel immunological and genomics strategies. Conf. of Research Workers in Animal Diseases, Porte Alegro, Brazil, September 2007.

US Veterinary Immune Reagent Network: Prioritization & Progress - (Abstract)

Lunney, J.K., Baldwin, C., Black, S.J., Boyd, P., Lillehoj, H.S., Labresh, J., Horohov, D., Miller, N., Bengten, E., Chinchar, G., Wilson, M., Wagner, H.October 2007. Us veterinary immune reagent network: prioritization & progress. Proceedings Intl Symposium on Animal Genomics for Animal Health, Paris, France.P. 33.

Monoclonal antibodies reactive with chicken interleukin-17 - (Peer Reviewed Journal)

Yoo, J., Chang, H.H., Bae, Y., Seoung, C., Lillehoj, H.S., Min, W. 2008. Monoclonal antibodies reactive with chicken interleukin-17. Veterinary Immunology and Immunopathology. 121:359-363.

Antimicrobial activity of chicken NK-lysin against Eimeria sporozoites - (Peer Reviewed Journal)

Hong, Y.H., Lillehoj, H.S., Siragusa, G.R., Bannerman, D.D., Lillehoj, E.P. 2008. Antimicrobial activity of chicken NK-lysin against Eimeria sporozoites. Avian Diseases. 52:302-305.

Immunopathology and Cytokine Responses in Broiler Chickens Coinfected with Eimeria maxima and Clostridium perfringens Using an Animal Model of Necrotic Enteritis - (Peer Reviewed Journal)

Park, S.S., Allen, P., Lillehoj, H.S., Park, D., Fitzcoy, S., Bautista, D.A., Lillehoj, E.P. 2008. Immunopathology and Cytokine Responses in Broiler Chickens Coinfected with Eimeria maxima and Clostridium perfringens Using an Animal Model of Necrotic Enteritis. Avian Diseases. 52:14-22.

Transcriptional Response of Chicken Macrophages to Salmonella enterica serovar Enteritidis Infection - (Abstract)

Zhang, S., Lillehoj, H.S., Kim, C.H., Keeler, C.L., Zhang, M. 2007. Transcriptional Response of Chicken Macrophages to Salmonella enterica serovar Enteritidis Infection. International Symposium on Animal Genomics for Animal Health. Oct 20-27, Paris, France.

COMPARISON OF TRANSCRIPTIONAL RESONSES FROM AVIAN GUT TISSUES AFTER EIMERIA ACERVULINA AND E. MAXIMA INFECTIONS USING cDNA MICROARRAY TECHNOLOGY - (Abstract)

Kim, C.H., Lillehoj, H.S., Bliss, T.W., Keeler, C.L., Hong, Y.H., Park, D.W., Kim, D.K., Lee, S.H. 2007. Comparison of transcriptional resonses from avian gut tissues after eimeria acervulina and e. maxima infections using cdna microarray technology. International Symposium Animal Genomics for Animal Health. Oct 20-27. Paris, France.

DIFFERENTIAL CYTOKINE GENE EXPRESSION IN TWO GENETICALLY DISPARATE CHICKEN LINES IN RESPONSE TO INFECTION WITH EIMERIA MAXIMA - (Abstract)

Kim, D., Hong, Y.H., Park, D., Lamont, S.J., Lillehoj, H.S. 2007. Differential cytokine gene expression in two genetically disparate chicken lines in response to infection with eimeria maxima. Internation Symposium on Animal Genomics for Animal Health Meeting.Oct 20-27, Paris, France.

Immunomodulatory Effects of Safflower Leaf (Carthamus tinctorius) - (Peer Reviewed Journal)

Lee, S., Lillehoj, H.S., Heckert, R.A., Chun, H., Cho, S., Tuo, W. 2008. Immunomodulatory Effects of Safflower Leaf (Carthamus tinctorius)on Chicken lymphocytes and macrophages. Journal of Poultry Science. 45:147-151

Molecular and quantitative genetic approaches to investigate disease reistance mechanisms and novel vaccine strategy. - (Abstract)

Lillehoj, H.S. 2007. Molecular and quantitative genetic approaches to investigate disease reistance mechanisms and novel vaccine strategy. Proceedings of International Symposia on Annual Genomics for Animal Health. Oct. 23-25. Paris, France.

Application of immunogenomics to study intestinal innate and adaptive immunity against coccidia parasites. - (Abstract)

Lillehoj, H.S. 2007. Application of immunogenomics to study intestinal innate and adaptive immunity against coccidia parasites.Proceedings of Latin American Congress meeting, Sept. 24-29. Porto Alegra, Brazil.

Functional Characterization of Tumor Necrosis Factor Superfamily 15(TNFSF15) Induced by Lipopolysaccharides and Eimeria Infection - (Peer Reviewed Journal)

Park, S.S., Lillehoj, H.S., Hong, Y.H., Lee, S. 2007. Functional Characterization of Tumor Necrosis Factor Superfamily 15(TNFSF15) Induced by Lipopolysaccharides and Eimeria Infection. Developmental and Comparative Immunology 31:934-944.

Monoclonal antibodies against chicken interleukin-6 - (Peer Reviewed Journal)

Scott, T.R., Lillehoj, H.S. 2007. Monoclonal antibodies against chicken interleukin-6. Veterinary Immunology and Immunopathology 114:173-177.

IMMUNOMODULATORY EFFECTS OF SAFFLOWER LEAF (carthamus tinctorius) ON COCCIDIOSIS - (Abstract)

Lee, S., Lillehoj, H.S., Park, D., Hong, Y. 2007. Immunomodulatory effects of safflower leaf (carthamus tinctorius) on coccidiosis, April 25, 2007, BARC Poster Day.

Characterization of novel lytic peptide secreted by intestinal intraepithelial lymphocytes infected with coccidia - (Proceedings/Symposium)

Lillehoj, H.S., Lee, S.H, Jenkins, M.C., Hong, Y.H. 2007. Characterization of novel lytic peptide secreted by intestinal intraepithelial lymphocytes infected with coccidia. Proceedings of American Avian Veterinary Pathologists meeting. July 14-18. Washington, D.C.

Analysis of Chicken Cytokine and Chemokine Gene Expression Following Eimeria acervulina and Eimeria tenella Infections - (Peer Reviewed Journal)

Hong, Y.H., Lillehoj, H.S., Lee, S., Dalloul, R.A., Lillehoj, E. 2007. Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections. Veterinary Immunology and Immunopathology. 114:220-223.

Cytokine gene expression profile in Fayoumi chicken after Eimeria maxima infection - (Proceedings/Symposium)

Lillehoj, H.S., Kim, D.K., Hong, Y.H., Park, D.W., Lamont, S.J. 2007. Cytokine gene expression profile in Fayoumi chicken after Eimeria maxima infection. Proceedings of America Avian Veterinary Pathologists Meeting. July 14-18, Washington, D.C. P 119.

Changes in Immune-Related Chicken Cytokine and Chemokine Gene Expression Following Eimeria Infection - (Proceedings/Symposium)

Lillehoj, H.S., Hong, Y.H. 2007. Changes in Immune-Related Chicken Cytokine and Chemokine Gene Expression Following Eimeria Infection. Proceedings of Association of Avian Veterinary Pathologists Meetings, July 14-18, Washington DC. P 118.

Molecular Cloning and Characterization of Chicken Lipopolysaccharide-Induced TNF-alpha Factor (LITAF) - (Peer Reviewed Journal)

Hong, Y.H., Lillehoj, H.S., Lee, S.H., Park, D.W., Lillehoj, E.P. 2007. Molecular Cloning and Characterization of Chicken Lipopolysaccharide-Induced TNF-alpha Factor (LITAF). Developmental and Comparative Immunology 30:919-929.

Passive Protection Against Coccidiosis - (Abstract)

Lillehoj, H.S. 2007. Passive Protection Against Coccidiosis. Proceedings of Association of National Poultry Science. April 19-25. Acapulco, Mexica. P13.

Immunogenomics approaches to study host innate immunity against intestinal parasites - (Proceedings/Symposium)

Lillehoj, H.S. 2008. Immunogenomics approaches to study host innate immunity against intestinal parasites. Proceedings of Korean Society of Poultry Science. p. 17.

Genomics and vaccine development - (Peer Reviewed Journal)

Gay, C.G., Zuerner, R., Bannantine, J.P., Lillehoj, H.S., Zhu, J., Green, R.D., Pastoret, P.P. 2007. Genomics and vaccine development. OIE Rev. Sci Tech. 26:49-67.

Effects of Pediococcus and Saccharomyces-based Probiotic (MitoMax) on Coccidiosis in Broiler Chickens - (Peer Reviewed Journal)

Lee, S., Lillehoj, H.S., Park, D.W., Hong, Y.H., Lin, J.J. 2007. Effects of Pediococcus and Saccharomyces-based Probiotic (MitoMax) on Coccidiosis in Broiler Chickens. Comparative Immunology Microbiology and Infectious Diseases 30:261-268.

Anticoccidial effect of green tea-based diets against Eimeria maxima - (Peer Reviewed Journal)

Jang, S.I., Jun, M., Lillehoj, H.S., Dalloul, R.A., Kong, I.K., Kim, S., Min, W. 2007. Anticoccidial effect of green tea-based diets against Eimeria maxima. Veterinary Parasitology 144:172-175.

Characterization of chicken TNFSF15 and it's role in coccidiosis - (Abstract)

Lillehoj, H.S., Park, S.S. 2007. Characterization of chicken TNFSF15 and it's role in coccidiosis. American Association of Immunologists Proceedings. May 18-22. Miami Beach, Florida.

Changes in Immune-Related Gene Expression and Intestinal Lymphocyte Subpopulations Following Eimeria maxima Infection of Chickens - (Peer Reviewed Journal)

Hong, Y.H., Lillehoj, H.S., Lillehoj, E.P., Lee, S.H. 2007. Changes in immune-related gene rxpression and intestinal lymphocyte subpopulations following Eimeria maxima infection of chickens. Veterinary Immunology and Immunopathology. 114:259-272.

Innate immune response to Clostridium perfringens and Eimeria maxima in necrotic enteritis model - (Proceedings/Symposium)

Lillehoj, H.S., Park, S.S., Allen, P., Park, D.W., Fitzcoy, S., Bautista, D.A. 2007. Innate immune response to Clostridium perfringens and Eimeria maxima in necrotic enteritis model.Proceedings of America Avian veterinary pathologists, July 14-18, Washington, D.C.

US Veterinary Immune Reagents Network - (Proceedings/Symposium)

Lillehoj, H.S., Lunney, J.K., Baldwin, C., Labresh, J., Horohov, D., Habsen, J., Miller, N., Bengton, E., Chinchar, G., Wilson, M., Wagner, B. 2008. Us veterinary immune reagents network. Proceedings of American Avian Veterinary Pathologists meeting July 14-18, Washington D.C.

Unique Responses of the Avian Macrophage to Different Species of Eimeria - (Peer Reviewed Journal)

Dalloul, R.A., Bliss, T.W., Hong, Y.H., Ben Chouikha, I., Park, D., Keeler Jr, C.L., Lillehoj, H.S. 2007. Unique Responses of the Avian Macrophage to Different Species of Eimeria. Molecular Immunology 44:558-566.

In ovo administration of CpG oligodeoxynucleotides and the recombinant microneme protein MIC2 protects against Eimeria infections - (Peer Reviewed Journal)

Dalloul, R.A., Lillehoj, H.S., Klinman, D.M., Ding, X., Min, W., Heckert, R.A., Lillehoj, E.P. 2006. In ovo administration of CpG oligodeoxynucleotides and the recombinant microneme protein MIC2 protects against Eimeria infections . Vaccine 23:3108-3113.

Differential Responses of Macrophages to Salmonella enterica Serovars Enteritidis and Typhimurium - (Peer Reviewed Journal)

Okamura, M., Lillehoj, H.S., Raybourne, R.B., Babu, U.S., Heckert, R.A., Sasai, K., Baba, E., Lillehoj, E.P. 2006. Differential Responses of Macrophages to Salmonella enterica Serovars Enteritidis and Typhimurium. Veterinary Immunology and Immunopathology 107:327-335.

Identification of protective innate immune mechanisms in coccidiosis and salmonellosis - (Proceedings/Symposium)

Lillehoj, H.S. 2006. Identification of protective innate immune mechanisms in coccidiosis and salmonellosis. Proceedings of CSREES NRI Project Leader Meeting. Dec 3, Chicago, IL.

THE FIRST CHARACTERIZATION OF MACROPHAGE MIGRATION INHIBITORY FACTOR (MIF) MOLECULES FROM APICOMPLEXAN PARASITES BELONGING TO GENUS EIMERIA, THE CAUSATIVE AGENTS OF CHICKEN COCCIDIOSIS. - (Peer Reviewed Journal)

Miska, K.B., Fetterer, R.H., Lillehoj, H.S., Jenkins, M.C., Allen, P.C., Harper, S. 2007. The first characterization of macrophage migration inhibitory factor (mif) molecules from apicomplexan parasites belonging to genus Eimeria, the causative agents of chicken coccidiosis. Molecular and Biochemical Parasitology. 151:173-183.

US Veterinary Immune Reagents Network - (Abstract)

Baldwin, C., Lunney, J.K., Lillehoj, H.S., Lebresh, J., Horohov, D., Hansen, J., Miller, N., Bengton, E., Chinchar, G., Wilson, M., Wagner, B. 2006. Us veterinary immune reagents network. In: R. Ellis Ed., Porceedings of the 2006 CRWAD meeting, Chicago, IL, December 3-5, 2006. Blackwell Publishing. p. 71

Molecular cloning and characterization of chicken NK lysin - (Peer Reviewed Journal)

Hong, Y.H., Lillehoj, H.S., Dalloul, R.A., Miska, K.B., Tuo, W., Lee, S., Han, J., Lillehoj, E.P. 2006. Molecular cloning and characterization of chicken NK lysin. Infection and Immunity. 110:339-347.

Avian Coccidiosis: recent advancements in control measures and vaccine development - (Peer Reviewed Journal)

Dalloul, A.A., Lillehoj, H.S. 2006. Avian Coccidiosis: recent advancements in control measures and vaccine development. Expert Review of Vaccines. 5:143-163.

Immunopotentiating Effect of a Fomitella fraxinea Derived Lectin on Chicken Immunity and Resistance to Coccidiosis - (Peer Reviewed Journal)

Dalloul, R.A., Lillehoj, H.S., Lee, J., Lee, S., Chung, K. 2006. Immunopotentiating Effect of a Fomitella fraxinea Derived Lectin on Chicken Immunity and Resistance to Coccidiosis. Poultry Science. 85:446-451.

Supplementary effect by harvest period of Lentinus edodes on the levels of blood glucose and serum lipid in diabetic KK mice - (Peer Reviewed Journal)

Lee, S., Park, H., Cho, S., Jung, H., Cho, S., Lillehoj, H.S. 2006. Supplementary effect by harvest period of Lentinus edodes on the levels of blood glucose and serum lipid in diabetic KK mice. J. Korean Soc. Food. Sci. Nutr. 34:738-742.

Effects of Acorn (Quercus acutissima CARR.) Supplementation on Acetylcholine and Its Related Enzyme Activities in Brain of Dementia Model Mouse - (Peer Reviewed Journal)

Lee, S., Kim, D., Cho, S., Jung, H., Cho, S., Park, H., Lillehoj, H.S. 2006. Effects of Acorn (Quercus acutissima CARR.) Supplementation on Acetylcholine and Its Related Enzyme Activities in Brain of Dementia Model Mouse. J. Korean Soc. Food. Sci. Nutri. 34:738-742.

Supplementary Effects of Lentinus edodes with Different Harvest Period and Part on Neurotransmitters and Lipid peroxide levels in the Brain of Diabetic Mice - (Peer Reviewed Journal)

Park, H., Kim, D., Lee, S., Lee, Y., Jeong, H., Cho, S., Chun, H., Lillehoj, H.S. 2006. Supplementary Effects of Lentinus edodes with Different Harvest Period and Part on Neurotransmitters and Lipid peroxide levels in the Brain of Diabetic Mice. Journal of Korean Poultry Science 34:1182-1187.

Functional genomics approaches to study host pathogen interactions to mucosal pathogens - (Abstract)

Lillehoj, H.S. 2006. Functional genomics approaches to study host pathogen Functional genomics approaches to study host pathogens interactions to mucosal pathogens.Proceedings of the Korean Society of Poultry Science Meeting, Nov. 10, Suwon, Korean.

ANALYSIS OF CHICKEN EMBRYONIC GONAD ESTS - (Peer Reviewed Journal)

Shini, J.H., Kim, H., Lim, D., Jeon, M., Hani, B.K., Park, T.S., Kim, J.K., Lillehoj, H.S., Cho, B.W., Han, J.Y. 2006. Analysis of chicken embryonic gonad ests. Animal Genetics 37:85-86.

MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF CHICKEN NK LYSIN - (Abstract)

Lillehoj, H.S., Hong, Y.H. 2006. Molecular and functional characterization of chicken nk lysin. Proceedings of Frontiers in Basic Immunology September 28-29. NIH, Bethesda, MD.

KINETIC CHANGES IN IMMUNE-RELATED GENE EXPRESSION AND INTESTINAL LYMPHOCYTE SUBPOPULATIONS FOLLOWING E. MAXIMA INFECTION - (Abstract)

Hong, Y.H., Lillehoj, H.S., Lee, S.H., Dalloul, R. 2006. Kinetic changes in immune-related gene expression and intestinal lymphocyte subpopulations following e. maxima infection. Proceedings of International Avian Immunology Research Group Meeting. Oct 21-24, Paris, France. P 64.

CLONING AND CHARACTERIZATION OF CHICKEN NK-LYSIN AND LIPOPOLYSACCHARIDE-INDUCED TNF-ALPHA FACTOR (LITAF) - (Abstract)

Hong, Y.H., Lillehoj, H.S., Dalloul, R.A., Lee, S.H. 2006. Cloning and characterization of chicken nk-lysin and lipopolysaccharide-induced tnf-alpha factor (litaf). Proceedigs of International Avian Immunology Research Group Meeting. Oct. 21-24. Paris, France. P 28.

CPG OLIGODEOXYNUCLEOTIDES-MEDIATED IMMUNOMODULATION OF MIC2 RECOMBINANT VACCINE-INDUCED PROTECTION AGAINST COCCIDIOSIS - (Abstract)

Dalloula, R.A., Lillehoj, H.S., Klinman, D.M. 2006.Cpg oligodeoxynucleotides-mediated immunomodulation of mic2 recombinant vaccine-induced protection against coccidiosis. Proceedings of International Avian Immunology Research Group Meeting. Oct. 21-24. Paris, France. P 99.

INVESTIGATION OF INNATE IMMUNE RESPONSE TO THREE DIFFERENT EIMERIA SPECIES USING CHICKEN CDNA MACROPHAGE MICROARRAY - (Abstract)

Dalloul, R.A., Bliss, T.W., Hong, Y.H., Park, D.W., Keeler, C.L., Lillehoj, H.S. 2008. Investigation of innate immune response to three different eimeria species using chicken cdna macrophage microarray. International Research Group Meeting. Oct 21-24. Paris, France.

APPLICATION OF MACROPHAGE AND INTESTINAL CDNA MICROARRAYS TO STUDY INNATE MUCOSAL IMMUNITY IN AVIAN COCCIDIOSIS - (Abstract)

Lillehoj, H.S. 2006. Application of macrophage and intestinal cdna microarrays to study innate mucosal immunity in avian coccidiosis. July 16-19, Edmonton, Canada. P2

APPLICATION OF MACROPHAGE AND INTESTINAL CDNA MICROARRAYS TO STUDY INNATE MUCOSAL IMMUNITY IN AVIAN COCCIDIOSIS - (Abstract)

Lillehoj, H.S. 2006. Application of macrophage and intestinal cdna microarrays to study innate mucosal immunity in avian coccidiosis [abstract]. Annual Poultry Science Assoc. Mtg, Edmonton, Canada. p. 2.

NK-LYSIN: HIGH LEVEL OF LOCAL GENE EXPRESSION IN COCCIDIOSIS - (Abstract)

Lillehoj, H.S., Hong, Y.H., Dalloul, R.A., Miska, K.B., Tuo, W., Lee, S., Han, J., Lillehoj, E.P. 2006. Nk-lysin: high level of local gene expression in coccidiosis.May 12-16, Boston, MA. P43.

CLONING AND CHARACTERIZATION OF CHICKEN LIPOPOLYSACCHARIDE-INDUCED TNF-A FACTOR - (Abstract)

Hong, Y.H., Lillehoj, H.S., Lee, S., Park, S.S., Lillehoj, E.P. 2006. Cloning and characterization of chicken lipopolysaccharide-induced tnf-a factor. Proceedings of Association of American Immunologists. May 12-16,Boston, MA. p43.

IMMUNOMODULATORY EFFECTS OF TRADITIONAL MEDICINAL KOREN PLANTS IN SPAFAS CHICKENS - (Abstract)

Lee, S., Lillehoj, H.S., Chun, H., Park, H., Cho, S., Park, D., Heckert, R.A. 2006. Immunomodulatory effects of traditional medicinal koren plants in spafas chickens. Proceedings of BARC poster Day. April 26.Beltsville, Md.

THE U.S. VETERINARY IMMUNE REAGENTS NETWORK - (Abstract)

Baldwin, C., Hansen, J.D., Horohov, D., Labresh, J., Lillehoj, H.S., Lunney, J.K., Miller, N.W., Wilson, M., Bengten, E., Chinchar, G., Wagner, B. 2006. The U.S. veterinary immune reagents network. In: Proceedings of International Veterinary Vaccines and Diagnostics Conference, June 25-29, 2006, Oslo, Norway. p. 34.

IDENTIFICATION AND CHARACTERIZATION OF THE PEROXIREDOXIN GENE FAMILY IN AVES - (Peer Reviewed Journal)

Han, J., Song, K., Shin, J., Han, B., Park, T., Park, H., Kim, J., Lillehoj, H.S., Lim, J., Kim, H. 2005. Identification and characterization of the peroxiredoxin gene family in aves. Poultry Science 84:1432-1438.

IN OVO VACCINATION WITH THE EIMERIA TENELLA ETMIC2 GENE INDUCES PROTECTIVE IMMUNITY AGAINST COCCIDIOSIS - (Peer Reviewed Journal)

Ding, X., Lillehoj, H.S., Dalloul, R.A., Min, W., Sato, T., Yasuda, A., Lillehoj, E.P. 2005. In ovo vaccination with the eimeria tenella etmic2 gene induces protective immunity against coccidiosis. Vaccine. 23:3733-3740.

THE MACROPHAGE INHIBITORY FACTOR OF EIMERIA SPECIES - (Abstract)

Miska, K.B., Lillehoj, H.S., Allen, P.C., Fetterer, R.H., Jenkins, M.C. 2005. The macrophage inhibitory factor of eimeria species. Coccidiosis International Conference Proceedings. p. 163.

CHARACTERIZATION OF SERINE PROTEASES IN DEVELOPMENTAL STAGES OF EIMERIA TENELLA - (Abstract)

Fetterer, R.H., Miska, K.B., Allen, P.C., Lillehoj, H.S., Barfield, R.C. 2005. Characterization of serine proteases in developmental stages of eimeria tenella. Coccidiosis International Conference Proceedings. p. 165.

THE DEVELOPMENTAL EXPRESSION OF EIMERIA HEAT SHOCK PROTEIN 90 - (Abstract)

Miska, K.B., Lillehoj, H.S., Fetterer, R.H. 2005. The developmental expression of eimeria heat shock protein 90. Coccidiosis International Conference Proceedings, p. 163.

EFFECTS OF DIETARY PHYTIC ACID ON THE SERUM LIPID LEVELS IN AGED MICE - (Abstract)

Chun, H., Lee, S., Cho, S., Chung, H., Park, H., Cho, S., Lee, Y., Lillehoj, H.S. 2005. Effects of dietary phytic acid on the serum lipid levels in aged mice.Proceedings of International Symposium on Triglycerides, p. 21.

MOLECULAR CLONING AND EXPRESSION PROFILES OF CHICKEN NK-LYSIN DURING EIMERIA INFECTIONS. - (Abstract)

Hong, Y.H., Lillehoj, H.S., Dalloul, R.A., Miska, K.B., Lee, S.H. 2005. Molecular cloning and expression profiles of chicken nk-lysin during eimeria infections.. Coccidiosis International Conference Proceedings, p. 153.

EMBRYO VACCINATION AGAINST EIMERIA TENELLA AND E. ACERVULINA INFECTIONS USING RECOMBINANT PROTEINS AND CYTOKINE ADJUVANTS - (Peer Reviewed Journal)

Lillehoj, H.S., Ding, X., Dalloul, R.A., Sato, T., Yasuda, A., Kukkegih, E.P. 2005. Embryo vaccination against Eimeria tenella and E. acervulina infections using recombinant proteins and cytokine adjuvants. Journal of Parasitology. 91:666-673.

RESISTANCE TO INTESTINAL COCCIDIOSIS FOLLOWING DNA IMMUNIZATION WITH THE CLONED 3-1E EIMERIA GENE PLUS IL-2, IL-15, AND IFN-GAMMA - (Peer Reviewed Journal)

Lillehoj, H.S., Ding, X., Quiroz, M.A., Berensee, E., Lillehoj, E.P. 2005. Resistance to intestinal coccidiosis following dna immunization with the cloned 3-1E Eimeria gene plus IL-2, IL-15, and IFN-gamma. Avian Diseases. 49:112-117.

SEQUENCE AND FUNCTIONAL PROPERTIES OF CHICKEN INTERLEUKIN-16 - (Peer Reviewed Journal)

Min, W., Lillehoj, H.S. 2005. Sequence and functional properties of chicken interleukin-16. Developmental and Comparative Immunology 28:153-162.

EST ANALYSIS O EIMERIA-STIMULATED INTETINAL INTRAEPITHELIAL LYMPHOCYTES IN CHICKENS - (Peer Reviewed Journal)

Min, W., Lillehoj, H.S., Ashwell, C.M., Van Tassell, C.P., Dalloul, R.A., Matukumalli, L.K., Han, J.Y., Lillehoj, E.P. 2005. Est analysis of Eimeria-stimulated intestinal intraepithelial lymphocytes in chickens. Molecular Biotechnology. 30:143-150.

ISOLATION AND CHARACTERIZATION OF CHICKEN INTERLEUKIN-17 CDNA - (Peer Reviewed Journal)

Min, W., Lillehoj, H.S. 2005. Isolation and characterization of chicken interleukin-17 cdna. Journal of Interferon and Cytokine Research 22:1125-1130.

PROTECTIVE IMMUNITY AGAINST EIMERIA ACERVULINA FOLLOWING IN OVO IMMUNIZATION WITH A RECOMBINANT SUBUNIT VACCINE AND CYTOKINE GENES. - (Peer Reviewed Journal)

Ding, X., Lillehoj, H.S., Quiroz, M.A., Berensee, E., Lillehoj, E.P. 2005. Protective immunity against Eimeria acervulina following in ovo immunization with a recombinant subunit vaccine and cytokine genes. Infection and Immunity.72:6939-6944.

CPG OLIGODEOXYNUCLEOTIDES CO-ADMINISTERED WITH THE MICRONEME PROTEIN MIC2 PROTECT AGAINST EIMERIA INFECTIONS. - (Proceedings/Symposium)

Dalloul, R.A., Lillehoj, H.S., Klinman, D.M., Ding, X., Min, W., Heckert, R.A., Lillehoj, E.P. 2005. Cpg oligodeoxynucleotides co-administered with the microneme protein mic2 protect against eimeria infections.. Annual Conference on Vaccine Research 64.

APPLICATION OF BIOTECHNOLOGICAL TOOLS FOR COCCIDIA VACCINE DEVELOPMENT. - (Peer Reviewed Journal)

Min, W., Dalloul, R.A., Lillehoj, H.S. 2005. Application of biotechnological tools for coccidia vaccine development. Korean Journal of Veterinary Science. 5:279-288.

RECENT ADVANCES IN IMMUNOMODULATION AND VACCINATION STRATEGIES AGAINST COCCIDIOSIS. - (Review Article)

Dallul, R.A., Lillehoj, H.S. 2005. Recent advances in immunomodulation and vaccination strategies against coccidiosis. Avian Diseases. 48:1-8.

CYROKINES AND IMMUNITY TO EIMERIA. RECENT PROGRESS ON THE CYTOKINE REGULATION OF INTESTINAL IMMUNE RESPONSES TO EIMERIA. - (Peer Reviewed Journal)

Lillehoj, H.S., Dalloul, R., Min, W. 2005. Cyrokines and immunity to eimeria. recent progress on the cytokine regulation of intestinal immune responses to eimeria. Poultry Science 83:611-623.

CHARACTERIZATION OF STAGE-SPECIFIC AND CROSS-REACTIVE ANTIGENS FROM EIMERIA ACERVULINA BY CHICKEN MONOCLONAL ANTIBODIES. - (Peer Reviewed Journal)

Constantinoiu, C.C., Lillehoj, H.S., Matsubayashi, M., Hoshoda, Y., Tani, H., Matsuda, H., Sasai, H., Baba, E. 2005. Characterization of stage-specific and cross-reactive antigens from eimeria acervulina by chicken monoclonal antibodies. Journal of Veterinary Medical Science 66:403-408

DEVELOPMENT AND CHARACTERIZATION OF A RECOMBINANT CHICKEN SINGLE-CHAIN FV ANTIBODY DETECTING EIMERIA ACERVULINA SPOROZOITE ANTIGEN. - (Peer Reviewed Journal)

Park, K., Park, D., Kim, C., Han, B.K., Park, T.S., Han, J.Y., Lillehoj, H.S., Kim, J.K. 2005. Development and characterization of a recombinant chicken single-chain fv antibody detecting eimeria acervulina sporozoite antigen.Biotechnology Letters. 27:289-295.

SALMONELLA ENTERITIDIS CLEARANCE AND IMMUNE RESPONSES IN CHICKENS FOLLOWING SALMONELLA VACCINATION AND CHALLENGE. - (Peer Reviewed Journal)

Babu, U., Dalloul, R.A., Okamura, M., Lillehoj, H.S., Xie, H., Raybourne, R.B., Gaines, D., Heckert, R.A. 2005. Salmonella enteritidis clearance and immune responses in chickens following salmonella vaccination and challenge.Veterinary Immunology and Immunopathology. 101:251-257.

CROSS-REACTIVITIES WITH CRYPTOSPORIDIUM SPP. BY CHICKEN MONOCLONAL ANTIBODIES THAT RECOGNIZE AVIAN EIMERIA SPP. - (Peer Reviewed Journal)

Matsubayashi, M., Kimata, I., Iseki, M., Lillehoj, H.S., Matsuda, H., Nakanishi, T., Tani, H., Sasai, K., Baba, E. 2005. Cross-reactivities with cryptosporidium spp. by chicken monoclonal antibodies that recognize avian Eimeria spp. Veterinary Parasitology. 128:47-57.

INCREASED LYMPHOCYTE SUBPOPULATIONS AND MACROPHAGES IN THE OVARIES AND OVIDUCTS OF LAYING HENS INFECTED WITH SALMONELLA ENTERICA SEROVAR ENTERITIDIS - (Peer Reviewed Journal)

Withanage, G.K., Sasai, K., Fukata, T., Miyamoto, T., Lillehoj, H.S., Baba, E. 2005. Increased lymphocyte subpopulations and macrophages in the ovaries and oviducts of laying hens infected with salmonella enterica serovar enteritidis. Avian Pathology 32:583-590.

ISOLATION AND CHARACTERIZATION OF CDNAS ENCODING CHICKEN IL-16 AND IL-17 - (Abstract)

Lillehoj, E.P., Min, W., Lillehoj, H.S. 2005. Isolation and characterization of cdnas encoding chicken il-16 and il-17. International Cytokine Society Annual Meeting p. 35.

MOLECULAR ANALYSIS OF HEAT SHOCK PROTEIN 90 (HSP90) IN SPECIES OF EIMERIA RESPONSIBLE FOR COCCIDIOSIS IN POULTRY. - (Abstract)

Miska, K.B., Fetterer, R.H., Min, W., Lillehoj, H.S. 2004. Molecular analysis of heat shock protein 90 (hsp90) in species of Eimeria responsible for coccidiosis in poultry. American Association of Avian Pathologists. 91:300-306.

IN VIVO EFFECT OF CPG OLIGODEOXYNUCLEOTIDE ON EIMERIA INFECTION IN CHICKENS. - (Peer Reviewed Journal)

Dalloul, R.A., Lillehoj, H.S., Okamura, M., Xie, H., Min, W., Ding, X., Heckert, R.A. 2004. In vivo effect of cpg oligodeoxynucleotide on Eimeria infection in chickens. Avian Diseases. 48:783-790.

SALMONELLA ENTERITIDIS CLEARANCE AND IMMUNE RESPONSES IN CHICKENS FOLLOWING SALMONELLA VACCINATION AND CHALLENGE - (Peer Reviewed Journal)

Babu, U., Dalloul, R.A., Okamura, M., Lillehoj, H.S., Xie, H., Raybourne, R.B., Gaines, D., Heckert, R.A. 2004. Salmonella enteritidis clearance and immune responses in chickens following salmonella vaccination and challenge. Veterinary Immunology and Immunopathology 101:251-257.

CPG OLIGODEOXYNUCLEUTODES AS VACCINE ADJUVANTS TO EIMERIA IN CHICKENS - (Abstract)

Dalloul, R., Lillehoj, H.S., Ding, X., Min, W., Heckert, R.A., Klinman, D.M. 2004. Cpg oligodeoxynucleutodes as vaccine adjuvants to eimeria in chickens. American Veterinary Medical Association, p. 21

MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF CHICKEN IL-16 AND IL-17. - (Abstract)

Min, W., Lillehoj, H.S. 2004. Molecular and functional characterization of chicken il-16 and il-17.. Avian Immunology Group Meeting, p.33.

MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF AN ALTERNATIVELY SPLICED TRANSCRIPT ISOFORM OF THE COMMON CYTOKINE RECEPTOR GAMMA CHAIN - (Abstract)

Min, W., Lillehoj, H.S. 2004. Molecular and functional characterization of an alternatively spliced transcript isoform of the common cytokine receptor gamma chain. Avian Immunology Group Meeting, p. 83.

MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF AN ALTERNATIVELY SPLICED TRANSCRIPT ISOFORM OF THE COMMON CYTOKINE RECEPTOR GAMMA-CHAIN - (Abstract) - (01-May-04)

COMPLETE CITATION ADDED - (Abstract)

Okamura, M., Lillehoj, H.S., Raybourne, R., Babu, U., Heckert, R.A. 2004. Avian macrophage response against salmonellosis and the effect of ifn-gamma and cpg motif o the intracellular survival of salmonella. Avian Immunology Group Meeting, p. 91.

ANALYSIS OF EXPRESSED SEQUENCE TAGS (EST) CDNA LIBRARY FROM EIMERIA-ACTIVATED INTESTINAL INTRA-EPITHELIAL LYMPHOCYTES - (Abstract)

Lillehoj, H.S., Min, W., Ashwell, C.M., Van Tassell, C.P. 2004. Analysis of expressed sequence tags (est) cdna library from eimeria-activated intestinal intra-epithelial lymphocytes. Avian Immunology Group Meeting, p. 60.

HIGH-THROUGHPUT GENE EXPRESSION ANALYSIS USING T LYMPHOCYTE CDNA MICROARRAY TO IDENTIFY EIMERIA-INDUCED HOST GENES MEDIATING CELL-MEDIATED IMMUNITY AGAINST COCCIDOSIS. - (Abstract)

Lillehoj, H.S., Min, W. 2004. High-throughput gene expression analysis using t lymphocyte cdna microarray to identify eimeria-induced host genes mediating cell-mediated immunity against coccidosis.. Avian Immunology Group Meeting, p. 22.

FINE MAPPING OF QUANTITATIVE TRAIT LOCI (QTL) WHICH CONTROL DISEASE RESISTANCE TO EIMERIA INFECTION. - (Abstract)

Lillehoj, H.S., Min, W., Zhu, J., Emara, M. 2004. Fine mapping of quantitative trait loci (qtl) which control disease resistance to eimeria infection.. Avian Immunology Group Meeting, p. 22.

FINE MAPPINT OF QUANTITATIVE TRAIT LOCI (QTL) HIGH CONTROL DISEASE RESISTANCE TO EIMERIA INFECTION. - (Abstract) - (30-Apr-04)

ANALYSIS OF CROSS REACIVITY OF 5 NEW CHICKEN MONOCLONAL ANTIODIES WHICH RECOGNIZE THE APICAL COMPLEX OF EIMERIA USING CONFOID LASER IMMUN-FLUORESCENT ASSAY. - (Peer Reviewed Journal)

Constantinoiu, C.C., Lillehoj, H.S., Matsubayashi, M., Hoshoda, Y., Tani, H., Matsuda, J., Sasao, K., Baba, E. 2004. Analysis of cross reacivity of 5 new chicken monoclonal antiodies which recognize the apical complex of eimeria using confoid laser immun-fluorescent assay. Veterinary Parasitology. 118:29-35.

HIGH-THROUGHPUT GENE EXPRESSIION PROFILING OF HOST INTSTINAL IMMUNE RESPONSE TO EIMERIA. - (Abstract)

Lillehoj, H.S., Min, W. 2004. High-throughput gene expressiion profiling of host intstinal immune response to eimeria.. American Association of Immunologists Proceedings p. 212.

CPG-CONTAINING OLIGODEOXYNUCLEOTIDES PROTECT CHICKENS AGAINST EIMERIA INFECTIONS - (Abstract) - (01-Apr-04)

MOLECULAR CHARACTERIZATION OF CHICKEN IL-16 AND IL-17 - (Abstract)

Min, W., Lillehoj, H.S. 2004. Molecular characterization of chicken il-16 and il-17. American Association of Immunologists Proceedings p. 300.

IN OVO IMMUNIZATION WITH NAKED DNAS WHICH ENCODE COCCIDIA PROTEINS ELICITS ANTIGEN SPECIFIC IMMUNE RESPONSES AGAINST EIMERIA. - (Abstract) - (30-Mar-04)

GENE EXPRESSION PATTERNS IN DIFFERENTIALLY STIMULATED AVIAN MACROPHAGES. - (Abstract)

Bliss, T.W., Emara, M.G., Dohms, J.E., Lillehoj, H.S., Keeler, C.L. 2004. Gene expression patterns in differentially stimulated avian macrophages.. Veterinary Immunology International Symposium, p. 157.

DEVELOPMENT OF IN VITRO CYTOKINE ASSAYS FOR MEASURING INTESTINAL CELL-MEDIATED IMMUNE RESPONSES TO AVIAN COCIDIOSIS - (Peer Reviewed Journal) - (04-Mar-04)

IN OVO IMMUNIZATION WITH NAKED DNAS WHICH ENCODE COCCIDIA PROTEINS ELICITS ANTIGEN SPECIFIC IMMUNE RESPONSES AGAINST EIMERIA. - (Abstract)

Ding, X., Lillehoj, H.S., Queroz, M., Erich, B. 2004. In ovo immunization with naked dnas which encode coccidia proteins elicits antigen specific immune responses against eimeria.. American Association of Avian Pathologists, p. 22.

ENHANCEMENT OF INTESTINAL IMMUNITY TO COCCIDIOSIS USING CYTOKINES, OLIGODINUCLEOTIDES AND PROBOTICS - (Peer Reviewed Journal)

Lillehoj, H.S., Dalloul, R., Min, W. 2004. Enhancement of intestinal immunity to coccidiosis using cytokines, oligodinucleotides and probotics. World Poultry. Special Edition. 18-23.

PASSIVE PROTECTION AGAINST TWO EIMERIA SPECIES IN CHICKENS BY ORALLY ADMINISTERED ANTIBODIES SPECIFIC FOR A SINGLE EIMERIA PROTEIN - (Abstract)

Lillehoj, H.S., Ngyyen, S.Y., Donahue, J.P., Yokohama, A.H., Kodama, Y. 2004. Passive protection against two eimeria species in chickens by orally administered antibodies specific for a single eimeria protein. American Veterinary Medical Association Abstract p. 21.

PASSIVE PROTECTION AGAINST TWO EIMERIA SPECIES IN CHICKENS BY ORALLY ADMINISTERED ANTIBODIES SPECIFIC FOR A SINGLE EIMERIA PROTEIN - (Abstract)

Lillehoj, H.S., Ngyyen, S.V., Donahue, J.P., Yokohama, A.H., Kodama, Y. 2004. Passive protection against two eimeria species in chickens by orally administered antibodies specific for a single eimeria protein. American Association of Veterinary Parasitologists Proceedings p. 21.

PRODUCTION AND CHARATERIZATION OF MOUSE MONOCLONAL ANTIBODIES DETECTING E. TENELLA APICAL COMPLEX PROTEINS. - (Abstract)

Lillehoj, H.S., Ding, X., Fetterer, R.H., Kim, S.W. 2004. Production and charaterization of mouse monoclonal antibodies detecting e. tenella apical complex proteins.. American Association of Avian Pathologists Proceedings, p. 85.

ARE THERE IMMUNOVARIANTS OF COCCIDIA THAT CAN AFFECT VACCINE EFFICACY? (THE CLUES MAY NOT ALWAYS BE OBVIOUS) - (Peer Reviewed Journal) - (15-Dec-03)

EFFECTS OF LIVE ATTENUATED AND KILLED SALMONELLA VACCINE ON T-LYMPHOCYTE MEDIATED IMMUNITY IN LAYING HENS - (Peer Reviewed Journal)

Babu, U., Scott, M., Myers, M.J., Okamura, M., Gaines, D., Yancy, H.F., Lillehoj, H.S., Heckert, R., Raybourne, R. 2003. Effects of live attenuated and killed salmonella vaccine on t-lymphocyte mediated immunity in laying hens. Veterinary Immunology and Immunopathology. 91:39-44.

CYTOKINE REGULATION OF LOCAL HOST IMMUNE RESPONSES TO EIMERIA - (Abstract) - (01-Jul-03)

STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF CHICKEN INTERLEUKIN-16 AND INTERLEUKIN-17 CDNA - (Abstract) - (01-Jul-03)

SEQUENCE AND FUNCTIONAL PROPERTIES OF A NEW PROINFLAMMATORY CHICKEN CYTOKINE HOMOLOGOUS TO MAMMALIAN IL-16 - (Abstract) - (01-Jul-03)

ANTIGEN-SPECIFIC LYMPHOCYTE PROLIFERATION, INTERLEUKIN-6 (IL-6)AND IL-2 PRODUCTION IN CHICKENS IMMUNIZED WITH OUTER MEMBRANE PROTEIN OF SALMONELLA ENTERITIDIS - (Abstract)

Okamura, M., Lillehoj, H.S., Raybourne, R., Babu, U., Heckert, R. 2003. Antigen-specific lymphocyte proliferation, interleukin-6 (il-6)and il-2 production in chickens immunized with outer membrane protein of salmonella enteritidis.[abstract] American Association of Avian Pathologists. Paper No. 163.

CPG-INDUCED IMMUNOMODULATION AND INTRACELLULAR BACTERIAL KILLING IN A CHICKEN MACROPHAGE CELL LINE - (Peer Reviewed Journal) - (01-Jul-03)

AVIAN MACROPHAGE RESPONSE AGAINST SALMONELLA INFECTION AND THE EFFECTS OF IFN-GAMMA AND CPG MOTIF - (Abstract) - (01-Jul-03)

DIVERSE EXPRESSION OF THE K-1 ANTIGEN BY CORTICO-MEDULLARY AND RETICULAR EPITHELIAL CELLS OF THE BURSA OF FABRICIUS IN CHICKEN AND GUINEA FOWL - (Peer Reviewed Journal) - (01-Jul-03)

MOLECULAR CLONING AND CHARACTERIZATION OF A NEW PROINFLAMMATORY CHICKEN CYTOKINE WHICH INDUCES IL-6 PRODUCTION - (Abstract) - (30-Jun-03)

PHENOTYPIC VARIATION AMONG THREE BROILER PURE LINES FOR MAREK'S DISEASE, COCCIDIOSIS AND ANTIBODY RESPONSE TO SHEEP RED BLOOD CELLS. - (Peer Reviewed Journal) - (20-Jun-03)

MAPPING QUANTITATIVE TRAIT LOCUS ASSOCIATED WITH RESISTANCE TO AVIAN COCCIDIOSIS AND GROWTH - (Peer Reviewed Journal)

Zhu, J.J., Lillehoj, H.S., Allen, P.C., Van Tassell, C.P., Sonstegard, T.S., Cheng, H.H., Pollock, D., Sadjadi, M., Min, W., Emara, M.G. 2003. Mapping quantitative trait locus associated with resistance to avian coccidiosis and growth. Poultry Science 82:9-16.

CELL-MEDIATED IMMUNE RESPONSES TO A KILLED SALMONELLA ENTERITIDIS VACCINE: LYMPHOCYTE PROLIFERATION, T-CELL CHANGES AND INTERLEUKIN-6 (IL-6), IL-1, IL-2 AND IFN-GAMMA PRODUCTION - (Peer Reviewed Journal) - (15-Jun-03)

INTESTINAL IMMUNOMODULATION BY VITAMIN A DEFICIENCY AND LACTOBACILLUS - BASED PROBIOTIC IN EIMERIA ACERVULINA - INFECTED BROILER CHICKENS - (Peer Reviewed Journal)

Dalloul, R.A., Lillehoj, H.S., Shellem, T.A., Doerr, J.A. 2003. Intestinal immunomodulation by vitamin a deficiency and lactobacillus - based probiotic in eimeria acervulina - infected broiler chickens. Avian Diseases. 47:1313-1320.

IN OVO IMMUNOMODULATORY EFFECTS OF CPG-CONTAINING OLIGODEOXYNUCLEOTIDES IN EIMERIA-INFECTED CHICKENS - (Abstract) - (07-Jun-03)

A ROLE OF INTERFERON GAMMA IN AUTOIMMUNE VITILIGO OF SMYTH LINE CHICKENS - (Peer Reviewed Journal) - (05-Jun-03)

GENE EXPRESSION PROFILING TO STUDY 12 CYTOKINE PRODUCTION AFTER EIMERIA INFECTION - (Abstract) - (01-Jun-03)

IN VIVO EFFECTS OF CPG-ODN ON EIMERIA ACERVULINA-INFECTED SC AND TK CHICKENS - (Abstract) - (01-Jun-03)

HOST IMMUNITY AND VACCINE DEVELOPMENT TO COCCIDIA AND SALMONELLA INFECTIONS IN CHICKENS - (Peer Reviewed Journal)

Lillehoj, H.S., Okamura, M. 2003. Host immunity and vaccine development to coccidia and salmonella infections in chickens. Poultry Science. 40:151-193.

NITRIC OXIDE PRODUCTION BY MACROPHAGES STIMULATED WITH SPOROZOITES, LIPOPOLYSACCHARIDE, OR IFN-GAMMA AND ITS DYNAMIC CHANGES IN SC AND TK STRAINS OF CHICKENS INFECTED WITH EIMERIA TENELLA - (Peer Reviewed Journal)

Lillehoj, H.S., Li, G. 2003. Nitric oxide production by macrophages stimulated with sporozoites, lipopolysaccharide, or ifn-gamma and its dynamic changes in sc and tk strains of chickens infected with eimeria tenella. Avian Diseases. 48:244-253.

BEYOND GENOMICS REVOLUTION: EMERGENCE OF AGRICULTURAL BIOTECHNOLOGY - (Proceedings/Symposium) - (01-Dec-02)

GUT IMMUNE RESPONSES AND INTERVENTION STRATEGIES AGAINST EIMERIA AND SALMONELLA - (Proceedings/Symposium) - (01-Dec-02)

III. DISEASE RESISTANCE AND TRANSMISSION D. GENETIC RESISTANCE AND TRANSMISSION OF AVIAN PARASITES - (Book/Chapter)

Pinard-Van Der Laan, M.H., Lillehoj, H.S., Zhu, J.J. 2003. Disease resistance and transmission. Genetic resistance and transmission of avian parasites. In: Muir, W.M., Aggrey, S.E. Aggrey, editors. Poultry Genetics, Breeding and Biotechnology. United Kingdom: CABI Publishing. p.329-356.

AGE DIFFERENCE IN LYMPHOCYTE PROLIFERATION, IL-2 AND IFN-Y PRODUCTION FOLLOWING SALMONELLA ENTERITIDIS VACCINATION. - (Abstract) - (20-Nov-02)

PROFILING LOCAL GENE EXPRESSION CHANGES ASSOCIATED WITH EIMERIA INFECTIONS USING CDNA MICROARRAY - (Peer Reviewed Journal)

Min, W., Lillehoj, H.S., Kim, S., Zhu, J., Beard, H., Alkharouf, N., Matthews, B. 2003. Profiling local gene expression changes associated with eimeria infections using cdna microarray. Molecular Immunology. 62:392-399.

CELL-MEDIATED IMMUNITY AND INTERFERON GAMMA IN AUTOIMMUNE VITILIGO OF SMYTH LINE CHICKENS - (Abstract) - (10-Sep-02)

ASSOCIATIONS OF CHICKEN INTERFERON-Y GENOTYPE AND PROTEIN LEVEL WITH ANTIBODY RESPONSE KINETICS - (Peer Reviewed Journal)

Zhou, H., Lillehoj, H.S., Lamont, S.J. 2003. Association of chicken interferon-y genotype and protein level with antibody response kinetics. Avian Diseases. 46:869-876.

DEVELOPMENT AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES TO CHICKEN INTERLEUKIN-15 - (Peer Reviewed Journal) - (12-Jul-02)

INITIATION OF HUMORAL IMMUNITY - (Peer Reviewed Journal) - (30-Jun-02)

GENETIC DIVERSITY AT THE MAJOR HISTOCOMPATIBILITY COMPLEX (B) AND MICROSATTELITE LOCI IN THREE COMMERCIAL BROILER PURE LINES - (Peer Reviewed Journal) - (15-Jun-02)

PROFILING GENE EXPRESSION CHANGES ASSOCIATED WITH EIMERIA INFECTIONS USING HIGH-THROUGHPUT CDNA MICROARRAY - (Abstract)

MIN, W., LILLEHOJ, H.S., KIM, S., ZHU, J., BEARD, H., ALKHAROUF, N., MATTHEWS, B.F. PROFILING GENE EXPRESSION CHANGES ASSOCIATED WITH EIMERIA INFECTIONS USING HIGH-THROUGHPUT CDNA MICROARRAY. Annual Conference on Vaccine Research. 2003.

GENETIC MARKERS AND THEIR APPLICATION IN POULTRY BREEDING - (Abstract) - (30-May-02)

DIETARY MODULATION OF HOST PROTECTIVE IMMUNITY AGAINST AVIAN COCCIDIOSIS - (Abstract)

DALLOUL, R.A., LILLEHOJ, H.S., DOERR, J.A. DIETARY MODULATION OF HOST PROTECTIVE IMMUNITY AGAINST AVIAN COCCIDIOSIS. AMERICAN VETERINARY MEDICAL ASSOCIATION ABSTRACT. 2003.

DNA VACCINATION STRATEGY AGAINST AVIAN COCCIDIOSIS. - (Abstract) - (01-May-02)

IMMUNOMODULATORY EFFECTS OF VITAMIN A DEFICIENCY AND LACTOBACILLUS-BASED PROBIOTIC ON HOST IMMUNE RESPONSES IN EIMERIA ACERVULINA-INFECTED BROILERS - (Abstract) - (01-May-02)

IN VIVO EFFECTS OF CPG TREATMENT OF E. ACERVULINA INFECTED SC AND TL CHICKEN LINES - (Abstract) - (01-May-02)

PRODUCTION AND CHARACTERIZATION OF MONOCLONAL ANTIBODIES DETECTING THE CHICKEN INTERLEUKIN-1 RECEPTOR ALPHA CHAIN - (Abstract) - (01-May-02)

GENE EXPRESSION PROFILING EIMERIA-INFECTED CHICKENS USING CDNA MICROARRAY - (Abstract) - (01-May-02)

AGE DIFFERENCE IN LYMPHOCYTE PROLIFERATION AND IL-12 AND IFN-Y PRODUCTION FOLLOWING SALMONELLA ENTERITIDIS VACCINATION - (Abstract) - (01-May-02)

CELLULAR IMMUNE RESPONSES VACCINATED WITH SALMONELLA ENTERITIDIS BACTERIN - (Abstract)

OKARMURA, M., LILLEHOJ, H.S., BABU, U.S., RAYBOURNE, R.B., HECKERT, R.A. CELLULAR IMMUNE RESPONSES VACCINATED WITH SALMONELLA ENTERITIDIS BACTERIN. AMERICAN VETERINARY MEDICAL ASSOCIATION ABSTRACT. 2003.

IN VITRO STUDIES ON THE IMMUNOMODULATORY EFFECTS OF CPG MOTIFS AS POTENTIAL VACCINE ADJUVANTS - (Abstract) - (01-May-02)

S. ENTERITIDIS AND S. TYPHIMURIUM HAVE DIFFERENT PATHOGENIC MECHANISMS IN INFECTED HD 11 CELLS - (Abstract) - (01-May-02)

EFFECTS OF LIVE ATTENUATED AND KILLED SALMONELLA VACCINES ON CELL-MEDIATED IMMUNITY AMONG VERY YOUNG CHICKENS - (Abstract) - (01-May-02)

CHARACTERIZATION OF A SPONTANEOUSLY TRANSFORMED CHICKEN MACROPHAGE/MONOCYTIC CELL LINE HTC - (Abstract) - (01-May-02)

LIVE ATTENUATED AND KILLED SALMONELLA VACCINES CAUSE AN INCREASE IN CELL-MEDIATED IMMUNITY AMONG LAYING HENS - (Abstract) - (01-May-02)