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Important Exposure Factors
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The Food Quality Protection Act and Safe Drinking Water Act Amendments include special provisions that require EPA to assess all of the ways that children may come into contact with pesticides in their everyday environments. This requires a thorough understanding of the factors that affect children’s exposures to chemicals in the environment. The EPA Office of Research and Development (ORD) has conducted or supported several targeted observational studies to address critical data gaps in the Agency’s understanding of the factors affecting children’s exposures. Results from these studies are described in a new report, Important Exposure Factors for Children: an Analysis of Laboratory and Observational Field Data Characterizing Cumulative Exposure to Pesticides. This body of research provides important advancements in our understanding of factors that affect children’s exposures to chemicals in their environment.
The report integrates results from 13 different research studies that include pilot-scale and large observational exposure studies, as well as laboratory evaluations of sampling and analysis methods used in these studies. It includes real-world data which are critical for improving exposure assessments. The findings ensure that EPA exposure scientists, modelers and risk assessors have the most up-to-date scientific information available for use in developing more accurate risk assessments and risk reduction measures.
Fact Sheet: New Insights from EPA Describe Factors Affecting Children's Exposures to Pesticides (PDF) (2 pp, 80 KB)
Important Exposure Factors
Full document:
Important Exposure Factors for Children (PDF) (232 pp, 4M) - An Analysis of Laboratory and Observational Field Data Characterizing Cumulative Exposure to Pesticides
Download document by section:
- Cover page, Notice, Table of Contents, Abbreviations and Acronyms (PDF) (28 pp, 285 KB)
- Chapter 1. Introduction (PDF) (12 pp, 314 KB)
- Chapter 2. Pesticide Use Patterns (PDF) (12 pp, 416 KB)
- Chapter 3. Air Concentration Measurements (PDF) (22 pp, 869 KB)
- Chapter 4. Surface Measurements (PDF) (34 pp, 1M)
- Chapter 5. Dietary Exposure Measurements (PDF) (12 pp, 426 KB)
- Chapter 6. Indirect Ingestion Measurements (PDF) (12 pp, 302 KB)
- Chapter 7. Dermal Exposure Measurements (PDF) (24 pp, 1M)
- Chapter 8. Urinary Biomarker Measurements (PDF) (24 pp, 570 KB)
- Chapter 9. Summary and Conclusions (PDF) (2 pp, 112 KB)
- Chapter 10. References (PDF) (7 pp, 144 KB)
- Chapter 11. Bibliography (PDF) (3 pp, 102 KB)
- Appendix A. Summary Statistics and Appendix B. Individual Study Details(PDF) (24 pp, 1M)
Workshop on the Analysis of Children’s Measurement Data
The U.S. EPA National Exposure Research Laboratory held a Workshop on the Analysis of Children’s Measurement Data on September 27 and 28, 2005 in Research Triangle Park, NC. A group of experts in the fields of exposure and health assessments, toxicology, statistics, modeling, analytical chemistry, and biomarker measurements met to discuss currently available data on children’s exposures to pesticides, the draft report on Important Exposure Factors for Children, and additional analyses that could be performed with the data. Outputs from the workshop were used in developing the final report.
Full document:
Workshop Summary (PDF) (82 pp, 2M)
Download document by section:
- Workshop Report (PDF) (4 pp, 285 KB)
- Chapter 1: Introduction
- Chapter 2: Summary of the Workgroup Reports
- Chapter 3: Summary of the Open Discussion on Collaboration
- Appendix A: Individual Workgroup Materials
- Appendix B: Participant List
- Appendix C: Speaker Presentations
- Overview (PDF) (3 pp, 404 KB)
- CTEPP Study (PDF) (3 pp, 1M KB)
- Studies from Washington State (PDF) (12 pp, 1M)
- Biomarker Validation Study (PDF) (4 pp, 279 KB)
- Issues and Challenges (PDF) (5 pp, 245 KB)
- Regulatory Perspective (PDF) (4 pp, 160 KB)