DOE '99 Oakland Highlights
Meeting Intro
HGP Progress, Challenges
Joint Genome Institute
JGI Facility Opening
Sequencing
Device Speeds Sequencing
Chromosome 19 Genes
Functional Genomics
Sample Prep System
Informatics
Education & Bioethics
Microbial Genomes
Next Meeting Feb. 2000

Genome Project
Accelerated Timetable
FY1999 Budgets
JGI Refits Facility
Progress

In the News 
 Drosophila Near Completion
Directors, Researchers Receive Awards
Chromosomes 21, 22 Near Finish
Human MHC Region Sequenced
Mouse Probes Aid Mapping
Genetic Testing Committee
DOE Labs & Biomedicine
Biomedical Engineering Proposals
Drug Firms Create SNP Resource
SBIR 1999 Awards
HUGO News
1999 Hollaender Winners

Microbial Genomics 
EcoCyc Database for E. coli
Developing EcoCyc
Thermotoga Sequence
Clostridium Sequenced
Microbial Gene Finder
Neisseria Sequence
Microbial Web Sites

Ethical, Legal, and Social Issues
Education, Counseling Foundation
 ELSI Studies
ELSI Retrospective
Protecting Privacy

Informatics 
MGI 2.2 Released
DNA Repository

Web, Other Resources, Publications 
Metabolic Pathways
New Staden Package
PDB Newsletter
Polymorphism Database
Bacterial Protein Database
DOE BER Publications
HGP Information Web
Biotechnology Business Webs
Behavioral Genetics
Office of Science Reports
Articles on Genetics

Funding 
Genome Research Funding

Meeting Calendars & Acronyms 
Genome & Biotech Meetings 
Training Courses & Workshops 
Acronyms 

HGN archives & subscriptions 
HGP Information home

Oakland Hosts DOE Genome Program Contractor-Grantee Meeting '99

Report from 1999 DOE Genome Meeting

Enthusiasm ran high for the DOE Human Genome Program (HGP) in response to impressive gains reported at the Seventh DOE Contractor-Grantee meeting in January of this year. Convened every 12 to 18 months, this workshop provides an effective forum for all DOE HGP investigators and invited guests to discuss their research, initiate collaborations, and share new material resources and software capabilities.

Although traditionally held in Santa Fe, New Mexico, the 1999 meeting was moved to Oakland, California, so attendees could visit the new Production Sequencing Facility of DOE's Joint Genome Institute (JGI) in nearby Walnut Creek. Two years ago, JGI began operations under the direction of Elbert Branscomb to address the challenge of high-throughput sequencing, which remains the major task facing the HGP today. An overview of JGI progress.

Investigators representing other HGP- funded projects reported that exciting improvements in mapping and sequencing technologies resulted in higher throughput. New approaches to regulating gene expression are helping to assess whole-cell effects that are key to functional genomics. Attendees also discussed the application of genome sequencing information to real-life problems in medicine and waste cleanup. DOE is continuing activities to educate the general public about the HGP and its societal impact. Researchers in the Microbial Genome Program, a spinoff of HGP, reported impressive gains in whole-genome sequencing and analysis, proteomics, and comparative genomics.

Meeting Abstracts
More details of all HGP and MGP projects are in the DOE Contractor-Grantee meeting abstracts (www.ornl.gov/hgmis/publicat/99santa; print copies are available from HGMIS at Human Genome Management Information System (HGMIS), Oak Ridge National Laboratory, 1060 Commerce Park, MS 6480, Oak Ridge,TN 37830).

Next meeting

The electronic form of the newsletter may be cited in the following style:
Human Genome Program, U.S. Department of Energy, Human Genome News (v10n3-4).