The Integrated Risk Information System (IRIS) is a U.S. Environmental Protection Agency (EPA) database of chemical risk values that contains information on human health effects that may result from environmental exposures. The database is maintained by EPA's National Center for Environmental Assessment.
The IRIS process consists of development of a draft Toxicological Review for the chemical, internal and external scientific reviews of the draft document, EPA responses to review comments, and development and posting on the IRIS web site of an IRIS Summary and final Toxicological Review. Highlights of the current IRIS development process include a streamlined review schedule which should result in more human health assessments being available sooner to users of the IRIS database. Opportunities occur for federal agencies to provide scientific input during an interagency review process. DoD's Chemical and Material Risk Management office coordinates DoD's scientific review and submits consolidated comments to EPA. All interagency comments are made public by EPA.
GAO slams interagency review process that allows DoD input on science.
GAO testifies to how OMB facilitated interagency review slows IRIS process
Information related to the 16 January 2007 MERIT Information Exchange Meeting.
CRS Report on the OMB Risk Bulletin
EPA is soliciting public nominations for chemical substances for its 2007 agenda. EPA invites the public to submit nominations for substances to be considered for an assessment or reassessment in its IRIS Program.
The Framework for Metals Risk Assessment, released on March 8, 2007, outlines key principles about metals and describes how they should be considered in conducting human health and ecological risk assessments.
The Framework for Metals Risk Assessment, released on March 8, 2007, outlines key principles about metals and describes how they should be considered in conducting human health and ecological risk assessments.
EPA has announced an external review of the draft document Considerations for Developing Alternative Health Risk Assessment Approaches for Addressing Multiple Chemicals, Exposures and Effects (EPA/600/R-06/013A).
This report of the NRC Committee on Toxicity Testing and Assessment of Environmental Agents, prepared in response to EPAs request, envisions a major campaign in the scientific community to advance the science of toxicity testing.
In this draft notice, EPA announced its preliminary determinations for 11 contaminants listed on the second CCL. EPA had sufficient health and occurrence information to make the determination not to regulate 2,4-dinitrotoluene and 2,6-dinitrotoluene.
Exposure of wildlife to explosives and selected metals. Concentrations of contaminants in tissue are needed to estimate exposure of wildlife. In the absence of measured data, models are used.
A technical paper: Water Analysis: Emerging Contaminants and Current Issues by Dr. Susan D. Richardson National Exposure Research Laboratory, U.S. Environmental Protection Agency, Athens, Georgia 30605
The addendum to the World Health Organizations (WHO) third edition of the Guidelines has been comprehensively updated to take account of developments in risk assessment and risk management since the second edition.
Exposure of wildlife to explosives and selected metals. Concentrations of contaminants in tissue are needed to estimate exposure of wildlife. In the absence of measured data, models are used.
This is a May 2007 presentation explaining the California EPAs Green Chemistry Initiative.