National Toxicology Program

Formal Background Documents for a RoC nomination were first prepared for reviews for the 8th RoC that was published in 1998. The following is an alphabetized list of the available Background Documents and public comments for the nominations that have been reviewed for the RoC since 1996. No formal Background Documents for the nominations reviewed prior to 1996 are available.

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

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A

• Alcoholic Beverage Consumption
  • Summary of Information
  • Background Document(10.6 mb)
  • Public Comments
  • Summary of Committee Reviews
• 1-Amino-2,4,dibromoanthraquinone (ADBAQ)
  • Summary of Information
  • Background Document(2.7 mb)
  • Public Comments
  • RG1 Review Summary Document for ADBAQ(88.5 kb)
  • RG2 Review Summary Document for ADBAQ(29.4 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes 
• 2-Amino-3,4-dimethylimidazo[4-5-f]quinoline (MeIQ)
  • See Heterocyclic Amines (Selected)
• 2-Amino-3,8-dimethylimidazo[4-5-f]quinoxaline (MeIQx)
  • See Heterocyclic Amines (Selected)
• 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
  • See Heterocyclic Amines (Selected)
• 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ)
  • Summary of Information
  • Background Document(603.2 kb)
  • No Public Comments
  • Summary of Committee Reviews
• Aristolochic Acids
  • Summary of Information
  • Final Background Document(2.0 mb)
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (February 24, 2009)
• Azacitidine
  • Summary of Information
  • Background Document(3.7 mb)
  • No Public Comments
  • Summary of Committee Reviews

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B

• Beryllium and Beryllium Compounds
  • Summary of Information
  • Background Document(3.6 mb)
  • Public Comments
  • Summary of Committee Reviews
• 2,2-bis-(bromomethyl)-1,3-propanediol (BBMP) (Technical Grade)
  • Summary of Information
  • Background Document(8.3 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Boot & Shoe Manufacturing
  • Summary of Information
  • Background Document(4.2 mb)
  • Public Comments
  • Summary of Committee Reviews
• 1,3- Butadiene
  • Summary of Information
  • Background Document(9.2 mb)
  • Public Comments
  • Summary of Committee Reviews

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C

• Cadmium and Cadmium Compounds
  • Summary of Information
  • Background Document(13.8 mb)
  • Public Comments
  • Summary of Committee Reviews
• Captafol
  • Summary of Information
  • Final Background Document(790.0 kb)
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (February 24, 2009)
• Ceramic Fibers (Respirable Size)
  • Public Comments
• Chloramphenicol
  • Summary of Information
  • Background Document(315.1 kb)
  • Public Comments
  • Summary of Committee Reviews
• Chloroprene
  • Summary of Information
  • Background Document(6.1 mb)
  • Public Comments
  • Summary of Committee Reviews
• Chlorozotocin (CZT)
  • Summary of Information
  • Background Document(1.4 mb)
  • No Public Comments
  • Summary of Committee Reviews
• p -Chloro-o-toluidine and its Hydrochloride Salt
  • Summary of Information
  • Background Document(2.9 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Cobalt Sulfate
  • Summary of Information
  • Background Document(4.4 mb)
  • Public Comments
  • RG1 Review Summary Document for Cobalt Sulfate(91.6 kb)
  • RG2 Review Summary Document for Cobalt Sulfate(94.1 kb)
  • Cobalt Sulfate Commentary (RG2)(181.0 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• Cobalt-Tungsten Carbide Powders and Hard Metals
  • Summary of Information
  • Final Background Document(2.4 Mb)
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (June 21-22, 2010)

• Cyclosporin A
• Summary of Information
• Background Document(4.5 mb)
• No Public Comments
• Summary of Committee Reviews

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D

• Danthron (1,8-Dihydroxyanthraquinone)
  • Summary of Information
  • Background Document(2.2 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Diazoaminobenzene (DAAB)
  • Summary of Information
  • Background Document(2.6 mb)
  • No Public Comments
  • RG1 Review Summary Document for Diazoaminobenzene (DAAB)(65.0 kb)
  • RG2 Review Summary Document for Diazoaminobenzene (DAAB)(78.0 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• 2,3-Dibromo-1-propanol (DBP)
  • Summary of Information
  • Background Document(7.6 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Diesel Exhaust Particulates
  • Summary of Information
  • Background Document(7.6 mb)
  • Public Comments
  • Summary of Committee Reviews
• Diethanolamine (DEA)
  • Summary of Information
  • Background Document(9.7 mb)
  • Public Comments
  • RG1 Review Summary Document for Diethanolamine(72.8 kb)
  • RG2 Review Summary Document for Diethanolamine(81.7 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• 1,6-Dinitropyrene & 1,8-Dinitropyrene
  • Summary of Information
  • Background Document(4.4 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Disperse Blue I
  • Summary of Information
  • Background Document(2.2 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Dyes Metabolized to Benzidine (Benzidine Dyes as a Class)
  • Summary of Information
  • Background Document(8.6 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Dyes metabolized to 3,3'-Dimethoxybenzidine (DMOB)
  • Summary of Information
  • Background Document(10.3 mb)
  • Public Comments
  • Summary of Committee Reviews
• Dyes metabolized to 3,3'-Dimethylbenzidine (DMB)
  • Summary of Information
  • Background Document(9.5 mb)
  • Public Comments
  • Summary of Committee Reviews

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E

• Environmental Tobacco Smoke
  • Summary of Information
  • Background Document(25.5 mb)
  • Public Comments
  • Summary of Committee Reviews
• Estrogens,Steriodal
  • Summary of Information
  • Background Document(4.0 mb)
  • Public Comments
  • Summary of Committee Reviews
• Ethyl Acrylate
  • Summary of Information
  • Background Document(1.7 mb)
  • Public Comments
  • Summary of Committee Reviews
• Ethylene Oxide
  • Summary of Information
  • Background Document(10.7 mb)
  • Public Comments
  • Summary of Committee Reviews

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F

• Formaldehyde
  • Summary of Information
  • Final Background Document(3.3 mb)
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (June 21-22, 2010)
• Furan
  • Summary of Information
  • Background Document(3.2 mb)
  • No Public Comments
  • Summary of Committee Reviews

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G

• Gamma Radiation
  • See X-Radiation & Gamma Radiation and Neutrons
• Certain glass wool fibers (inhalable)
  • Summary of Information
  • Final Background Document (2.2 Mb)
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (June 21-22, 2010)

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H

• Hepatitis B Virus (HBV)
  • Summary of Information
  • Background Document(1.4 mb)
  • No Public Comments
  • RG1 Review Summary Document for Hepatitis B Virus (HBV)(65.7 kb)
  • RG2 Review Summary Document for Hepatitis B Virus (HBV)(78.2 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• Hepatitis C Virus (HCV)
  • Summary of Information
  • Background Document(834.3 kb)
  • No Public Comments
  • RG1 Review Summary Document for Hepatitis C Virus (HCV)(50.3 kb)
  • RG2 Review Summary Document for Hepatitis C Virus (HCV)(73.2 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• Heterocyclic Amines (Selected): PhIP, MeIQ, and MeIQx
  • Summary of Information
  • Background Document(886.5 kb)
  • Public Comments
    • 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ)
    • 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)
    • 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
  • RG1 Review Summary Document for Selected Heterocyclic Amines (HCAs)(185.6 kb)
  • RG2 Review Summary Document for Selected Heterocyclic Amines (HCAs)(31.3 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• Human Papillomaviruses (HPV): Some Genital-Mucosal Types
  • Summary of Information
  • Background Document(812.7 kb)
  • Public Comments
  • RG1 Review Summary Document for Human Papillomaviruses: Genital-Mucosal Types(54.0 kb)
  • RG2 Review Summary Document for Human Papillomaviruses: Genital-Mucosal Types(76.6 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes

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I

• Isoprene
  • Summary of Information
  • Background Document(3.6 mb)
  • Public Comments
  • Summary of Committee Reviews

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L

• Lead and Lead Compounds
  • Summary of Information
  • Background Document(953.3 kb)
  • Public Comments
  • RG1 Review Summary Document for Lead and Lead Compounds(75.4 kb)
  • RG2 Review Summary Document for Lead and Lead Compounds(78.0 kb)
  • < NTP BSC RoC Subcommittee Meeting Minutes

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M

• Methyleugenol
  • Summary of Information
  • Background Document(9.8 mb)
  • Public Comments
  • Summary of Committee Reviews
• Methyl-t-Butyl Ether (MtBE)
  • Summary of Information
  • Background Document(859.0 kb)
  • Public Comments
  • Summary of Committee Reviews

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N

• Naphthalene
  • Summary of Information
  • Background Document(11.8 mb)
  • Public Comments
  • RG1 Review Summary Document for Naphthalene(88.7 kb)
  • RG2 Review Summary Document for Naphthalene(32.5 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• Neutrons
  • See X-Radiation & Gamma Radiation and Neutrons
• Nickel Compounds
  • Summary of Information
  • Background Document(18.1 mb)
  • Public Comments
  • Summary of Committee Reviews
• Nickel (Metallic) and Certain Nickel Alloys
  • Summary of Information
  • Background Document(13.2 mb)
  • Public Comments
  • Summary of Committee Reviews
• o-Nitroanisole
  • Summary of Information
  • Background Document(2.7 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Nitrobenzene
  • Summary of Information
  • Background Document(450.8 kb)
  • Public Comments
  • RG1 Review Summary Document for Nitrobenzene(89.8 kb)
  • RG2 Review Summary Document for Nitrobenzene(29.4 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• 6-Nitrochrysene
  • Summary of Information
  • Background Document(3.2 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Nitromethane
  • Summary of Information
  • Background Document(14.6 mb)
  • Public Comments
  • RG1 Review Summary Document for Nitromethane(97.9 kb)
  • RG2 Review Summary Document for Nitromethane(92.8 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• 1-Nitropyrene
  • Summary of Information
  • Background Document(3.7 mb)
  • No Public Comments
  • Summary of Committee Reviews
• 4-Nitropyrene
  • Summary of Information
  • Background Document(1.6 mb)
  • No Public Comments
  • Summary of Committee Reviews
• ortho-Nitrotoluene
  • Summary of Information
  • Final Background Document(1.3 mb)
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (February 24, 2009)

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P

• Phenolphthalein
  • Summary of Information
  • Background Document(6.0 mb)
  • Public Comments
  • Summary of Committee Reviews

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R

• Riddelliine
  • Summary of Information
  • Final Background Document(1.4 mb)
  • No Public Comments
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (February 24, 2009)

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S

• Saccharin
  • Summary of Information
  • Background Document(15.4 mb)
  • Public Comments
  • Summary of Committee Reviews
• Silica, Crystalline (Respirable Size)
  • Summary of Information
  • Background Document(12.4 mb)
  • Public Comments
  • Summary of Committee Reviews
• Smokeless Tobacco
  • Summary of Information
  • Background Document(8.5 mb) (large .pdf file)
  • Public Comments
  • Summary of Committee Reviews
• Solar Radiation & Exposure to Sunlamps or Sunbeds
  • Summary of Information
  • Background Document(18.2 mb)
  • Public Comments
  • Summary of Committee Reviews
• Strong Inorganic Acid Mists Containing Sulfuric Acid
  • Summary of Information
  • Background Document(7.8 mb)
  • Public Comments
  • Summary of Committee Reviews
• Styrene
  • Summary of Information
  • Final Backound Document(2.9 mb) Erratum and Addendum
  • Public Comments
    • NTP Response to Public Comments (429 kb)
  • Expert Panel Meeting
  • NTP Board of Scientific Counselors Meeting (February 24, 2009)
  
  
• Styrene-7,8-oxide
  • Summary of Information
  • Background Document(2.7 mb)
  • Public Comments
  • Summary of Committee Reviews

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T

• Tamoxifen
  • Summary of Information
  • Background Document(9.5 mb)
  • Public Comments
  • Summary of Committee Reviews
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)
  • Summary of Information
  • Background Document(30.8 mb)
  • Public Comments
  • Summary of Committee Reviews
• Tetrafluoroethylene
  • Summary of Information
  • Background Document(4.8 mb)
  • Public Comments
  • Summary of Committee Reviews
• 4,4'-Thiodianiline
  • Summary of Information
  • Background Document(5.0 mb)
  • Public Comments
  • RG1 Review Summary Document for 4,4'-Thiodianiline(98.2 kb)
  • RG2 Review Summary Document for 4,4'-Thiodianiline(94.5 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes
• Thiotepa
  • Summary of Information
  • Background Document(2.2 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Tobacco Smoking
  • Summary of Information
  • Background Document(16.7 mb)
  • Public Comments
  • Summary of Committee Reviews
• 1,2,3-Trichloropropane
  • Summary of Information
  • Background Document(2.6 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Trichloroethylene (TCE)
  • Summary of Information
  • Background Documents
    • 1997 Review(9.4 mb)
    • 2000 Review(4.4 mb)
  • Public Comments
    • 1997 Review
    • 2000 Review
  • Summary of Committee Reviews

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U

• Ultraviolet (UV) Radiation, Broad Spectrum and UVA, UVB, and UVC
  • Summary of Information
  • Background Document(2.0 mb)
  • Public Comments
  • Summary of Committee Reviews

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V

• Vinyl Bromide
  • Summary of Information
  • Background Document(1.9 mb)
  • No Public Comments
  • Summary of Committee Reviews
• Vinyl Fluoride
  • Summary of Information
  • Background Document(579.6 kb)
  • No Public Comments
  • Summary of Committee Reviews

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W

• Wood Dust
  • Summary of Information
  • Background Document(5.7 mb)
  • Public Comments
  • Summary of Committee Reviews

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X

• X-Radiation & Gamma Radiation and Neutrons
  • Summary of Information
  • Background Document(1.4 mb)
  • Public Comments
  • RG1 Review Summary Document for X-Radiation & Gamma Radiation and Neutrons(83.4 kb)
  • RG2 Review Summary Document for X-Radiation & Gamma Radiation and Neutrons(85.4 kb)
  • NTP BSC RoC Subcommittee Meeting Minutes

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