Section on High Resolution Optical Imaging
Contents
Expertise
The NIBIB Section on High Resolution Optical Imaging (HROI) develops novel technologies
for studying biological processes at unprecedented speed and resolution. Research
interests and ongoing projects include:
- Furthering development of superresolution optical imaging
techniques, particularly 3-D photoactivated localization microscopy (PALM)
- Identification and screening of new photoactivable proteins
and dyes for use in PALM or conventional imaging
- Synthesis of novel non-diffracting light sheets and subsequent
application to selective plane illumination microscopy (SPIM)
- Improving multiphoton temporal focusing for high-speed
imaging of cells and embryos
- Development of high-speed, high-resolution THz microscope
for diagnosing skin cancer and imaging biological surfaces
- Construction of a 4-dimensional digital atlas of neuronal
development in C. Elegans in collaboration with researchers at Yale University and
Memorial Sloan-Kettering Cancer Center
Meet the Staff
Hari Shroff, Ph.D.
- Chief and Investigator
Yicong Wu, Ph.D.
- Staff Scientist
Andrew York, Ph.D.
- Research Fellow
Peter W. Winter, Ph.D.
- IRTA Postdoctoral Fellow
Peter Wawrzusin
- Postbac
Recent Publications
Nat Methods. 2012 May 13;9(7):749-754. doi: 10.1038/nmeth.2025.
Resolution doubling
in live, multicellular organisms via multifocal structured illumination microscopy.![External link, opens in new window External link, opens in new window](https://webarchive.library.unt.edu/web/20130217104539im_/http://www.nibib.nih.gov/nibib/image/externallink.gif)
York AG, Parekh SH, Nogare DD, Fischer RS, Temprine K, Mione M, Chitnis AB, Combs
CA, Shroff H.
Software Reference
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Last Updated On 01/31/2013