Pathway Interaction Database

Biomolecular interactions and cellular processes assembled into authoritative human signaling pathways

137 Human Pathways 9248 Interactions Curated by NCI-Nature

322 Human Pathways 7575 Interactions Imported from BioCarta/Reactome

Update: as of September 23, 2012 the PID is no longer being actively curated. NCI will maintain the PID website and data for twelve months beyond September 2012 to allow interested parties to obtain the previously curated data before the site is retired in September 2013.

Date last updated: 18 September 2012

Search database

Molecule name/ID or biological process term/ID

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Simple search help

You may enter molecule names, molecule IDs, biological process terms and/or biological process IDs as a comma-separated list. Molecule names may be any alias listed in Entrez Gene. Molecule IDs may be UniProt protein accession numbers, HUGO gene symbols, Entrez Gene IDs, and CAS numbers. Biological processes may be Gene Ontology (GO) terms, GO identifiers (entered in the format GO:0000000), and NCI thesaurus terms and identifiers.

Wildcard searches can be performed with search terms of 3 or more characters using the asterisk (*). For example, “Ras*” will find, among other terms, “Ras family”. Asterisks can be included at the beginning, end or both beginning and end of the term.

See the User guide for more information