3' -UTR-mediated translational regulation |
Reactome Imported |
3' -UTR-mediated translational regulation |
Reactome Imported |
Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression |
Reactome Imported |
APC-Cdc20 mediated degradation of Nek2A |
Reactome Imported |
Activated AMPK stimulates fatty-acid oxidation in muscle |
Reactome Imported |
Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix |
Reactome Imported |
Amine compound SLC transporters |
Reactome Imported |
Subnetwork: Na+/Cl- dependent neurotransmitter transporters |
Reactome Imported |
Subnetwork: Rhesus glycoproteins mediate ammonium transport. |
Reactome Imported |
Amino acid and oligopeptide SLC transporters |
Reactome Imported |
Subnetwork: Amino acid transport across the plasma membrane |
Reactome Imported |
Subnetwork: Organic anion transporters |
Reactome Imported |
Subnetwork: Proton-coupled neutral amino acid transporters |
Reactome Imported |
Subnetwork: Proton/oligonucleotide cotransporters |
Reactome Imported |
Apoptosis |
Reactome Imported |
Subnetwork: Activation and oligomerization of BAK protein |
Reactome Imported |
Subnetwork: Activation of BAD and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of BH3-only proteins |
Reactome Imported |
Subnetwork: Activation of BIM and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of BMF and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of DNA fragmentation factor |
Reactome Imported |
Subnetwork: Activation of NOXA and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of PUMA and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation of Pro-Caspase 8 |
Reactome Imported |
Subnetwork: Activation of caspases through apoptosome-mediated cleavage |
Reactome Imported |
Subnetwork: Activation, myristolyation of BID and translocation to mitochondria |
Reactome Imported |
Subnetwork: Activation, translocation and oligomerization of BAX |
Reactome Imported |
Subnetwork: Apoptosis induced DNA fragmentation |
Reactome Imported |
Subnetwork: Apoptotic cleavage of cell adhesion proteins |
Reactome Imported |
Subnetwork: Apoptotic cleavage of cellular proteins |
Reactome Imported |
Subnetwork: Apoptotic execution phase |
Reactome Imported |
Subnetwork: Apoptotic factor-mediated response |
Reactome Imported |
Subnetwork: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members |
Reactome Imported |
Subnetwork: Breakdown of the nuclear lamina |
Reactome Imported |
Subnetwork: Caspase-8 is formed from procaspase-8 |
Reactome Imported |
Subnetwork: Caspase-mediated cleavage of cytoskeletal proteins |
Reactome Imported |
Subnetwork: Cytochrome c-mediated apoptotic response |
Reactome Imported |
Subnetwork: Death Receptor Signalling |
Reactome Imported |
Subnetwork: Extrinsic Pathway for Apoptosis |
Reactome Imported |
Subnetwork: FasL/ CD95L signaling |
Reactome Imported |
Subnetwork: Formation of apoptosome |
Reactome Imported |
Subnetwork: Intrinsic Pathway for Apoptosis |
Reactome Imported |
Subnetwork: Regulation of Apoptosis |
Reactome Imported |
Subnetwork: Regulation of PAK-2p34 activity by PS-GAP/RHG10 |
Reactome Imported |
Subnetwork: Regulation of activated PAK-2p34 by proteasome mediated degradation |
Reactome Imported |
Subnetwork: Release of apoptotic factors from the mitochondria |
Reactome Imported |
Subnetwork: Role of DCC in regulating apoptosis |
Reactome Imported |
Subnetwork: SMAC binds to IAPs |
Reactome Imported |
Subnetwork: SMAC-mediated apoptotic response |
Reactome Imported |
Subnetwork: SMAC-mediated dissociation of IAP:caspase complexes |
Reactome Imported |
Subnetwork: Stimulation of the cell death response by PAK-2p34 |
Reactome Imported |
Subnetwork: TNF signaling |
Reactome Imported |
Subnetwork: TRAIL signaling |
Reactome Imported |
Axon guidance |
Reactome Imported |
Subnetwork: Activation of Rac |
Reactome Imported |
Subnetwork: CHL1 interactions |
Reactome Imported |
Subnetwork: CRMPs in Sema3A signaling |
Reactome Imported |
Subnetwork: DCC mediated attractive signaling |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: Inactivation of Cdc42 and Rac |
Reactome Imported |
Subnetwork: Interaction between L1 and Ankyrins |
Reactome Imported |
Subnetwork: L1CAM interactions |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: NCAM signaling for neurite out-growth |
Reactome Imported |
Subnetwork: NCAM1 interactions |
Reactome Imported |
Subnetwork: Netrin mediated repulsion signals |
Reactome Imported |
Subnetwork: Netrin-1 signaling |
Reactome Imported |
Subnetwork: Neurofascin interactions |
Reactome Imported |
Subnetwork: NrCAM interactions |
Reactome Imported |
Subnetwork: Other semaphorin interactions |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Subnetwork: Recycling pathway of L1 |
Reactome Imported |
Subnetwork: Regulation of Commissural axon pathfinding by Slit and Robo |
Reactome Imported |
Subnetwork: Role of Abl in Robo-Slit signaling |
Reactome Imported |
Subnetwork: Role of second messengers in netrin-1 signaling |
Reactome Imported |
Subnetwork: SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
Reactome Imported |
Subnetwork: Sema3A PAK dependent Axon repulsion |
Reactome Imported |
Subnetwork: Sema4D in semaphorin signaling |
Reactome Imported |
Subnetwork: Sema4D induced cell migration and growth-cone collapse |
Reactome Imported |
Subnetwork: Sema4D mediated inhibition of cell attachment and migration |
Reactome Imported |
Subnetwork: Semaphorin interactions |
Reactome Imported |
Subnetwork: Signal transduction by L1 |
Reactome Imported |
Subnetwork: Signaling by Robo receptor |
Reactome Imported |
Bile salt and organic anion SLC transporters |
Reactome Imported |
Subnetwork: Proton-coupled monocarboxylate transport |
Reactome Imported |
Subnetwork: Sodium-coupled sulphate, di- and tri-carboxylate transporters |
Reactome Imported |
Biological oxidations |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Amine Oxidase reactions |
Reactome Imported |
Subnetwork: Amino Acid conjugation |
Reactome Imported |
Subnetwork: Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 |
Reactome Imported |
Subnetwork: COX reactions |
Reactome Imported |
Subnetwork: CYP2E1 reactions |
Reactome Imported |
Subnetwork: Conjugation of benzoate with glycine |
Reactome Imported |
Subnetwork: Conjugation of carboxylic acids |
Reactome Imported |
Subnetwork: Conjugation of phenylacetate with glutamine |
Reactome Imported |
Subnetwork: Conjugation of salicylate with glycine |
Reactome Imported |
Subnetwork: Cytochrome P450 - arranged by substrate type |
Reactome Imported |
Subnetwork: Cytosolic sulfonation of small molecules |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Endogenous sterols |
Reactome Imported |
Subnetwork: Ethanol oxidation |
Reactome Imported |
Subnetwork: FMO oxidizes nucleophiles |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Formation of PAPS |
Reactome Imported |
Subnetwork: Formation of the active cofactor, UDP-glucuronate |
Reactome Imported |
Subnetwork: Glucuronidation |
Reactome Imported |
Subnetwork: Glutathione conjugation |
Reactome Imported |
Subnetwork: Glutathione synthesis |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Miscellaneous substrates |
Reactome Imported |
Subnetwork: Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 |
Reactome Imported |
Subnetwork: Phase 1 - Functionalization of compounds |
Reactome Imported |
Subnetwork: Phase II conjugation |
Reactome Imported |
Subnetwork: Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs |
Reactome Imported |
Subnetwork: Sterols are 12-hydroxylated by CYP8B1 |
Reactome Imported |
|
Reactome Imported |
|
Reactome Imported |
Botulinum neurotoxicity |
Reactome Imported |
Subnetwork: BoNT Light Chain Types A, C1, E cleave SNAP-25 |
Reactome Imported |
Subnetwork: BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin |
Reactome Imported |
Subnetwork: Proteolytic cleavage of SNARE complex proteins |
Reactome Imported |
Subnetwork: Translocation of BoNT Light chain |
Reactome Imported |
Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
Reactome Imported |
Cell Cycle Checkpoints |
Reactome Imported |
Subnetwork: Activation of ATR in response to replication stress |
Reactome Imported |
Subnetwork: Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
Reactome Imported |
Subnetwork: Amplification of signal from the kinetochores |
Reactome Imported |
Subnetwork: Autodegradation of the E3 ubiquitin ligase COP1 |
Reactome Imported |
Subnetwork: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex |
Reactome Imported |
Subnetwork: G1/S DNA Damage Checkpoints |
Reactome Imported |
Subnetwork: G2/M Checkpoints |
Reactome Imported |
Subnetwork: G2/M DNA damage checkpoint |
Reactome Imported |
Subnetwork: G2/M DNA replication checkpoint |
Reactome Imported |
Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex |
Reactome Imported |
Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
Reactome Imported |
Subnetwork: Mitotic Spindle Checkpoint |
Reactome Imported |
Subnetwork: Stabilization of p53 |
Reactome Imported |
Subnetwork: Transcriptional activation of cell cycle inhibitor p21 |
Reactome Imported |
Subnetwork: Transcriptional activation of p53 responsive genes |
Reactome Imported |
Subnetwork: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A |
Reactome Imported |
Subnetwork: p53-Dependent G1 DNA Damage Response |
Reactome Imported |
Subnetwork: p53-Dependent G1/S DNA damage checkpoint |
Reactome Imported |
Subnetwork: p53-Independent DNA Damage Response |
Reactome Imported |
Subnetwork: p53-Independent G1/S DNA damage checkpoint |
Reactome Imported |
Cell Cycle, Mitotic |
Reactome Imported |
Subnetwork: APC/C-mediated degradation of cell cycle proteins |
Reactome Imported |
Subnetwork: APC/C:Cdc20 mediated degradation of Cyclin B |
Reactome Imported |
Subnetwork: APC/C:Cdc20 mediated degradation of Securin |
Reactome Imported |
Subnetwork: APC/C:Cdc20 mediated degradation of mitotic proteins |
Reactome Imported |
Subnetwork: APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
Reactome Imported |
Subnetwork: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
Reactome Imported |
Subnetwork: Activation of the pre-replicative complex |
Reactome Imported |
Subnetwork: Assembly of the ORC complex at the origin of replication |
Reactome Imported |
Subnetwork: Assembly of the pre-replicative complex |
Reactome Imported |
Subnetwork: Association of licensing factors with the pre-replicative complex |
Reactome Imported |
Subnetwork: Autodegradation of Cdh1 by Cdh1:APC/C |
Reactome Imported |
Subnetwork: CDC6 association with the ORC:origin complex |
Reactome Imported |
Subnetwork: CDK-mediated phosphorylation and removal of Cdc6 |
Reactome Imported |
Subnetwork: CDT1 association with the CDC6:ORC:origin complex |
Reactome Imported |
Subnetwork: Centrosome maturation |
Reactome Imported |
Subnetwork: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
Reactome Imported |
Subnetwork: Cyclin A/B1 associated events during G2/M transition |
Reactome Imported |
Subnetwork: Cyclin A:Cdk2-associated events at S phase entry |
Reactome Imported |
Subnetwork: Cyclin B2 mediated events |
Reactome Imported |
Subnetwork: Cyclin D associated events in G1 |
Reactome Imported |
Subnetwork: Cyclin E associated events during G1/S transition |
Reactome Imported |
Subnetwork: DNA Replication Pre-Initiation |
Reactome Imported |
Subnetwork: DNA replication initiation |
Reactome Imported |
Subnetwork: DNA strand elongation |
Reactome Imported |
Subnetwork: E2F mediated regulation of DNA replication |
Reactome Imported |
Subnetwork: E2F-enabled inhibition of pre-replication complex formation |
Reactome Imported |
|
Reactome Imported |
Subnetwork: G1/S Transition |
Reactome Imported |
Subnetwork: G1/S-Specific Transcription |
Reactome Imported |
|
Reactome Imported |
Subnetwork: G2/M Transition |
Reactome Imported |
Subnetwork: Golgi Cisternae Pericentriolar Stack Reorganization |
Reactome Imported |
Subnetwork: Inactivation of APC/C via direct inhibition of the APC/C complex |
Reactome Imported |
Subnetwork: Inhibition of replication initiation of damaged DNA by Rb/E2F1 |
Reactome Imported |
Subnetwork: Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
Reactome Imported |
Subnetwork: Lagging Strand Synthesis |
Reactome Imported |
Subnetwork: Leading Strand Synthesis |
Reactome Imported |
Subnetwork: Loss of Nlp from mitotic centrosomes |
Reactome Imported |
Subnetwork: Loss of proteins required for interphase microtubule organization from the centrosome |
Reactome Imported |
|
Reactome Imported |
Subnetwork: M/G1 Transition |
Reactome Imported |
Subnetwork: Mitotic G1-G1/S phases |
Reactome Imported |
Subnetwork: Mitotic G2-G2/M phases |
Reactome Imported |
Subnetwork: Mitotic M-M/G1 phases |
Reactome Imported |
Subnetwork: Mitotic Metaphase/Anaphase Transition |
Reactome Imported |
Subnetwork: Mitotic Prometaphase |
Reactome Imported |
Subnetwork: Mitotic Prophase |
Reactome Imported |
Subnetwork: Mitotic Telophase /Cytokinesis |
Reactome Imported |
Subnetwork: Orc1 removal from chromatin |
Reactome Imported |
Subnetwork: Phosphorylation of Emi1 |
Reactome Imported |
Subnetwork: Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes |
Reactome Imported |
Subnetwork: Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes |
Reactome Imported |
Subnetwork: Phosphorylation of the APC/C |
Reactome Imported |
Subnetwork: Polo-like kinase mediated events |
Reactome Imported |
Subnetwork: Polymerase switching |
Reactome Imported |
Subnetwork: Processive synthesis on the lagging strand |
Reactome Imported |
Subnetwork: Recruitment of NuMA to mitotic centrosomes |
Reactome Imported |
Subnetwork: Recruitment of mitotic centrosome proteins and complexes |
Reactome Imported |
Subnetwork: Regulation of APC/C activators between G1/S and early anaphase |
Reactome Imported |
Subnetwork: Regulation of DNA replication |
Reactome Imported |
Subnetwork: Regulation of mitotic cell cycle |
Reactome Imported |
Subnetwork: Removal of licensing factors from origins |
Reactome Imported |
Subnetwork: Removal of the Flap Intermediate |
Reactome Imported |
|
Reactome Imported |
Subnetwork: SCF(Skp2)-mediated degradation of p27/p21 |
Reactome Imported |
Subnetwork: SCF-beta-TrCP mediated degradation of Emi1 |
Reactome Imported |
Subnetwork: Switching of origins to a post-replicative state |
Reactome Imported |
Subnetwork: Synthesis of DNA |
Reactome Imported |
Subnetwork: Ubiquitin-dependent degradation of Cyclin D |
Reactome Imported |
Subnetwork: Ubiquitin-dependent degradation of Cyclin D1 |
Reactome Imported |
Subnetwork: Unwinding of DNA |
Reactome Imported |
Cell junction organization |
Reactome Imported |
Subnetwork: Adherens junctions interactions |
Reactome Imported |
Subnetwork: Cell-cell junction organization |
Reactome Imported |
Subnetwork: Cell-extracellular matrix interactions |
Reactome Imported |
Subnetwork: Localization of the PINCH-ILK-PARVIN complex to focal adhesions |
Reactome Imported |
Subnetwork: Nectin/Necl trans heterodimerization |
Reactome Imported |
Subnetwork: Regulation of cytoskeletal remodeling and cell spreading by IPP complex components |
Reactome Imported |
Subnetwork: Tight junction interactions |
Reactome Imported |
Subnetwork: Type I hemidesmosome assembly |
Reactome Imported |
Chromosome Maintenance |
Reactome Imported |
Subnetwork: Deposition of New CENPA-containing Nucleosomes at the Centromere |
Reactome Imported |
Subnetwork: Extension of Telomeres |
Reactome Imported |
Subnetwork: Nucleosome assembly |
Reactome Imported |
Subnetwork: Packaging Of Telomere Ends |
Reactome Imported |
Subnetwork: Polymerase switching on the C-strand of the telomere |
Reactome Imported |
Subnetwork: Processive synthesis on the C-strand of the telomere |
Reactome Imported |
Subnetwork: Removal of the Flap Intermediate from the C-strand |
Reactome Imported |
Subnetwork: Telomere C-strand (Lagging Strand) Synthesis |
Reactome Imported |
Subnetwork: Telomere C-strand synthesis initiation |
Reactome Imported |
Subnetwork: Telomere Extension By Telomerase |
Reactome Imported |
Subnetwork: Telomere Maintenance |
Reactome Imported |
DNA Repair |
Reactome Imported |
Subnetwork: ABH2 mediated Reversal of Alkylation Damage |
Reactome Imported |
Subnetwork: ABH3 mediated Reversal of Alkylation Damage |
Reactome Imported |
Subnetwork: ATM mediated phosphorylation of repair proteins |
Reactome Imported |
Subnetwork: ATM mediated response to DNA double-strand break |
Reactome Imported |
Subnetwork: Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks |
Reactome Imported |
Subnetwork: Assembly of the RAD51-ssDNA nucleoprotein complex |
Reactome Imported |
Subnetwork: Base Excision Repair |
Reactome Imported |
Subnetwork: Base-Excision Repair, AP Site Formation |
Reactome Imported |
Subnetwork: Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
Reactome Imported |
Subnetwork: Cleavage of the damaged purine |
Reactome Imported |
Subnetwork: Cleavage of the damaged pyrimidine |
Reactome Imported |
Subnetwork: DNA Damage Bypass |
Reactome Imported |
Subnetwork: DNA Damage Recognition in GG-NER |
Reactome Imported |
Subnetwork: DNA Damage Reversal |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Depyrimidination |
Reactome Imported |
Subnetwork: Displacement of DNA glycosylase by APE1 |
Reactome Imported |
Subnetwork: Double-Strand Break Repair |
Reactome Imported |
Subnetwork: Dual incision reaction in GG-NER |
Reactome Imported |
Subnetwork: Dual incision reaction in TC-NER |
Reactome Imported |
Subnetwork: Fanconi Anemia pathway |
Reactome Imported |
Subnetwork: Formation of incision complex in GG-NER |
Reactome Imported |
Subnetwork: Formation of transcription-coupled NER (TC-NER) repair complex |
Reactome Imported |
Subnetwork: Gap-filling DNA repair synthesis and ligation in GG-NER |
Reactome Imported |
Subnetwork: Gap-filling DNA repair synthesis and ligation in TC-NER |
Reactome Imported |
Subnetwork: Global Genomic NER (GG-NER) |
Reactome Imported |
Subnetwork: Homologous DNA pairing and strand exchange |
Reactome Imported |
Subnetwork: Homologous Recombination Repair |
Reactome Imported |
Subnetwork: Homologous recombination repair of replication-independent double-strand breaks |
Reactome Imported |
Subnetwork: MRN complex relocalizes to nuclear foci |
Reactome Imported |
Subnetwork: Nonhomologous End-joining (NHEJ) |
Reactome Imported |
Subnetwork: Nucleotide Excision Repair |
Reactome Imported |
Subnetwork: Presynaptic phase of homologous DNA pairing and strand exchange |
Reactome Imported |
Subnetwork: Processing of DNA double-strand break ends |
Reactome Imported |
Subnetwork: Processing of DNA ends prior to end rejoining |
Reactome Imported |
Subnetwork: Recognition and association of DNA glycosylase with site containing an affected purine |
Reactome Imported |
Subnetwork: Recognition and association of DNA glycosylase with site containing an affected pyrimidine |
Reactome Imported |
Subnetwork: Recruitment of repair and signaling proteins to double-strand breaks |
Reactome Imported |
Subnetwork: Regulation of the Fanconi anemia pathway |
Reactome Imported |
Subnetwork: Removal of DNA patch containing abasic residue |
Reactome Imported |
Subnetwork: Repair synthesis for gap-filling by DNA polymerase in TC-NER |
Reactome Imported |
Subnetwork: Repair synthesis of patch ~27-30 bases long by DNA polymerase |
Reactome Imported |
Subnetwork: Resolution of AP sites via the multiple-nucleotide patch replacement pathway |
Reactome Imported |
Subnetwork: Resolution of AP sites via the single-nucleotide replacement pathway |
Reactome Imported |
Subnetwork: Resolution of Abasic Sites (AP sites) |
Reactome Imported |
Subnetwork: Resolution of D-loop structures |
Reactome Imported |
Subnetwork: Resolution of D-loop structures through Holliday junction intermediates |
Reactome Imported |
Subnetwork: Resolution of D-loop structures through synthesis-dependent strand-annealing |
Reactome Imported |
Subnetwork: Reversal of Alkylation Damage By DNA Dioxygenases |
Reactome Imported |
Subnetwork: Transcription-coupled NER (TC-NER) |
Reactome Imported |
Subnetwork: Translesion synthesis by DNA polymerases bypassing lesion on DNA template |
Reactome Imported |
Subnetwork: Translesion synthesis by HREV1 |
Reactome Imported |
Subnetwork: Translesion synthesis by Pol eta |
Reactome Imported |
Subnetwork: Translesion synthesis by Pol zeta |
Reactome Imported |
DNA Replication |
Reactome Imported |
Subnetwork: Activation of the pre-replicative complex |
Reactome Imported |
Subnetwork: Assembly of the ORC complex at the origin of replication |
Reactome Imported |
Subnetwork: Assembly of the pre-replicative complex |
Reactome Imported |
Subnetwork: Association of licensing factors with the pre-replicative complex |
Reactome Imported |
Subnetwork: CDC6 association with the ORC:origin complex |
Reactome Imported |
Subnetwork: CDK-mediated phosphorylation and removal of Cdc6 |
Reactome Imported |
Subnetwork: CDT1 association with the CDC6:ORC:origin complex |
Reactome Imported |
Subnetwork: DNA Replication Pre-Initiation |
Reactome Imported |
Subnetwork: DNA replication initiation |
Reactome Imported |
Subnetwork: DNA strand elongation |
Reactome Imported |
Subnetwork: Golgi Cisternae Pericentriolar Stack Reorganization |
Reactome Imported |
Subnetwork: Lagging Strand Synthesis |
Reactome Imported |
Subnetwork: Leading Strand Synthesis |
Reactome Imported |
|
Reactome Imported |
Subnetwork: M/G1 Transition |
Reactome Imported |
Subnetwork: Mitotic M-M/G1 phases |
Reactome Imported |
Subnetwork: Mitotic Metaphase/Anaphase Transition |
Reactome Imported |
Subnetwork: Mitotic Prometaphase |
Reactome Imported |
Subnetwork: Mitotic Prophase |
Reactome Imported |
Subnetwork: Mitotic Telophase /Cytokinesis |
Reactome Imported |
Subnetwork: Orc1 removal from chromatin |
Reactome Imported |
Subnetwork: Polymerase switching |
Reactome Imported |
Subnetwork: Processive synthesis on the lagging strand |
Reactome Imported |
Subnetwork: Regulation of DNA replication |
Reactome Imported |
Subnetwork: Removal of licensing factors from origins |
Reactome Imported |
Subnetwork: Removal of the Flap Intermediate |
Reactome Imported |
Subnetwork: Switching of origins to a post-replicative state |
Reactome Imported |
Subnetwork: Synthesis of DNA |
Reactome Imported |
Subnetwork: Unwinding of DNA |
Reactome Imported |
Diabetes pathways |
Reactome Imported |
Subnetwork: Activation of Chaperones by ATF6-alpha |
Reactome Imported |
Subnetwork: Activation of Chaperones by IRE1alpha |
Reactome Imported |
Subnetwork: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) |
Reactome Imported |
Subnetwork: Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
Reactome Imported |
Subnetwork: Insulin Synthesis and Processing |
Reactome Imported |
Subnetwork: PERK regulated gene expression |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Acetylcholine |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Fatty Acids Bound to GPR40 (FFAR1) |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Free Fatty Acids |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
Reactome Imported |
Subnetwork: Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
Reactome Imported |
Subnetwork: Synthesis, Secretion, and Deacylation of Ghrelin |
Reactome Imported |
Subnetwork: Unfolded Protein Response |
Reactome Imported |
Elevation of cytosolic Ca2+ levels |
Reactome Imported |
Elongation arrest and recovery |
Reactome Imported |
Gene Expression |
Reactome Imported |
Subnetwork: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
Reactome Imported |
Subnetwork: Cap-dependent Translation Initiation |
Reactome Imported |
Subnetwork: Cleavage of Growing Transcript in the Termination Region |
Reactome Imported |
Subnetwork: Cytosolic tRNA aminoacylation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Elongation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Initiation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Termination |
Reactome Imported |
Subnetwork: Formation and Maturation of mRNA Transcript |
Reactome Imported |
Subnetwork: Formation of RNA Pol II elongation complex |
Reactome Imported |
Subnetwork: Formation of a pool of free 40S subunits |
Reactome Imported |
Subnetwork: Formation of the Early Elongation Complex |
Reactome Imported |
Subnetwork: Formation of the ternary complex, and subsequently, the 43S complex |
Reactome Imported |
Subnetwork: GTP hydrolysis and joining of the 60S ribosomal subunit |
Reactome Imported |
Subnetwork: Generic Transcription Pathway |
Reactome Imported |
Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression |
Reactome Imported |
Subnetwork: Mitochondrial tRNA aminoacylation |
Reactome Imported |
Subnetwork: Notch-HLH transcription pathway |
Reactome Imported |
Subnetwork: Nuclear Receptor transcription pathway |
Reactome Imported |
Subnetwork: Peptide chain elongation |
Reactome Imported |
Subnetwork: Processing of Capped Intron-Containing Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped Intronless Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped Transcripts |
Reactome Imported |
Subnetwork: Processing of Intronless Pre-mRNAs |
Reactome Imported |
Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE |
Reactome Imported |
Subnetwork: RNA Polymerase II Pre-transcription Events |
Reactome Imported |
Subnetwork: RNA Polymerase II Promoter Escape |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation And Promoter Clearance |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Termination |
Reactome Imported |
Subnetwork: Recycling of eIF2:GDP |
Reactome Imported |
Subnetwork: Ribosomal scanning and start codon recognition |
Reactome Imported |
Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP independent Processing of Histone Pre-mRNAs |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Translation initiation complex formation |
Reactome Imported |
Subnetwork: Transport of Mature Transcript to Cytoplasm |
Reactome Imported |
Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts |
Reactome Imported |
Subnetwork: Transport of the SLBP Dependant Mature mRNA |
Reactome Imported |
Subnetwork: Transport of the SLBP independent Mature mRNA |
Reactome Imported |
Subnetwork: mRNA 3'-end processing |
Reactome Imported |
|
Reactome Imported |
Subnetwork: mRNA Splicing |
Reactome Imported |
Subnetwork: mRNA Splicing - Major Pathway |
Reactome Imported |
Subnetwork: mRNA Splicing - Minor Pathway |
Reactome Imported |
Subnetwork: tRNA Aminoacylation |
Reactome Imported |
HIV Infection |
Reactome Imported |
Subnetwork: 2-LTR circle formation |
Reactome Imported |
Subnetwork: APOBEC3G mediated resistance to HIV-1 infection |
Reactome Imported |
Subnetwork: Abortive elongation of HIV-1 transcript in the absence of Tat |
Reactome Imported |
Subnetwork: Autointegration results in viral DNA circles |
Reactome Imported |
Subnetwork: Binding and entry of HIV virion |
Reactome Imported |
Subnetwork: Early Phase of HIV Life Cycle |
Reactome Imported |
Subnetwork: Formation of HIV-1 elongation complex containing HIV-1 Tat |
Reactome Imported |
Subnetwork: Formation of HIV-1 elongation complex in the absence of HIV-1 Tat |
Reactome Imported |
Subnetwork: Formation of the HIV-1 Early Elongation Complex |
Reactome Imported |
Subnetwork: HIV Life Cycle |
Reactome Imported |
Subnetwork: HIV-1 Transcription Elongation |
Reactome Imported |
Subnetwork: HIV-1 Transcription Initiation |
Reactome Imported |
Subnetwork: HIV-1 elongation arrest and recovery |
Reactome Imported |
Subnetwork: Host Interactions of HIV factors |
Reactome Imported |
Subnetwork: Integration of provirus |
Reactome Imported |
Subnetwork: Integration of viral DNA into host genomic DNA |
Reactome Imported |
Subnetwork: Interactions of Rev with host cellular proteins |
Reactome Imported |
Subnetwork: Interactions of Tat with host cellular proteins |
Reactome Imported |
Subnetwork: Interactions of Vpr with host cellular proteins |
Reactome Imported |
Subnetwork: Late Phase of HIV Life Cycle |
Reactome Imported |
Subnetwork: Minus-strand DNA synthesis |
Reactome Imported |
Subnetwork: Nef Mediated CD4 Down-regulation |
Reactome Imported |
Subnetwork: Nef Mediated CD8 Down-regulation |
Reactome Imported |
Subnetwork: Nef and signal transduction |
Reactome Imported |
Subnetwork: Nef mediated downregulation of CD28 cell surface expression |
Reactome Imported |
Subnetwork: Nef mediated downregulation of MHC class I complex cell surface expression |
Reactome Imported |
Subnetwork: Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters |
Reactome Imported |
Subnetwork: Nuclear import of Rev protein |
Reactome Imported |
Subnetwork: Pausing and recovery of HIV-1 elongation |
Reactome Imported |
Subnetwork: Pausing and recovery of Tat-mediated HIV-1 elongation |
Reactome Imported |
Subnetwork: Plus-strand DNA synthesis |
Reactome Imported |
Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE |
Reactome Imported |
Subnetwork: RNA Polymerase II HIV-1 Promoter Escape |
Reactome Imported |
Subnetwork: Rev-mediated nuclear export of HIV-1 RNA |
Reactome Imported |
Subnetwork: Reverse Transcription of HIV RNA |
Reactome Imported |
Subnetwork: Tat-mediated HIV-1 elongation arrest and recovery |
Reactome Imported |
Subnetwork: Tat-mediated elongation of the HIV-1 transcript |
Reactome Imported |
Subnetwork: The role of Nef in HIV-1 replication and disease pathogenesis |
Reactome Imported |
Subnetwork: Transcription of the HIV genome |
Reactome Imported |
Subnetwork: Uncoating of the HIV Virion |
Reactome Imported |
Subnetwork: Vif-mediated degradation of APOBEC3G |
Reactome Imported |
Subnetwork: Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization |
Reactome Imported |
Subnetwork: Vpr-mediated nuclear import of PICs |
Reactome Imported |
Subnetwork: Vpu mediated degradation of CD4 |
Reactome Imported |
Hemostasis |
Reactome Imported |
Subnetwork: ADP signalling through P2Y purinoceptor 1 |
Reactome Imported |
Subnetwork: ADP signalling through P2Y purinoceptor 12 |
Reactome Imported |
Subnetwork: Adrenaline signalling through Alpha-2 adrenergic receptor |
Reactome Imported |
Subnetwork: Arachidonate production from DAG |
Reactome Imported |
Subnetwork: Basigin interactions |
Reactome Imported |
Subnetwork: Cell surface interactions at the vascular wall |
Reactome Imported |
Subnetwork: Collagen adhesion via GPVI |
Reactome Imported |
Subnetwork: Collagen adhesion via Gp IV |
Reactome Imported |
Subnetwork: Collagen adhesion via alpha 2 beta 1 glycoprotein |
Reactome Imported |
Subnetwork: Common Pathway |
Reactome Imported |
Subnetwork: Disinhibition of SNARE formation |
Reactome Imported |
Subnetwork: Dissolution of Fibrin Clot |
Reactome Imported |
Subnetwork: Effects of PIP2 hydrolysis |
Reactome Imported |
Subnetwork: Extrinsic Pathway |
Reactome Imported |
Subnetwork: Formation of Fibrin Clot (Clotting Cascade) |
Reactome Imported |
Subnetwork: Formation of Platelet plug |
Reactome Imported |
Subnetwork: GPVI-mediated activation cascade |
Reactome Imported |
Subnetwork: Grb2:SOS provides linkage to MAPK signaling for Intergrins |
Reactome Imported |
Subnetwork: Integrin alphaIIbbeta3 signaling |
Reactome Imported |
Subnetwork: Intrinsic Pathway |
Reactome Imported |
Subnetwork: PECAM1 interactions |
Reactome Imported |
Subnetwork: Platelet Activation |
Reactome Imported |
Subnetwork: Platelet Adhesion to exposed collagen |
Reactome Imported |
Subnetwork: Platelet Aggregation (Plug Formation) |
Reactome Imported |
Subnetwork: Platelet activation triggers |
Reactome Imported |
Subnetwork: Platelet degranulation |
Reactome Imported |
Subnetwork: Response to elevated platelet cytosolic Ca2+ |
Reactome Imported |
Subnetwork: Signal amplification |
Reactome Imported |
Subnetwork: Thrombin signalling through proteinase activated receptors (PARs) |
Reactome Imported |
Subnetwork: Thromboxane signalling through TP receptor |
Reactome Imported |
Subnetwork: Tie2 Signaling |
Reactome Imported |
Subnetwork: p130Cas linkage to MAPK signaling for integrins |
Reactome Imported |
Subnetwork: vWF interaction with collagen |
Reactome Imported |
Hormone biosynthesis |
Reactome Imported |
Subnetwork: Amine-derived hormones |
Reactome Imported |
Subnetwork: Androgen biosynthesis |
Reactome Imported |
Subnetwork: Catecholamine biosynthesis |
Reactome Imported |
Subnetwork: Estrogen biosynthesis |
Reactome Imported |
Subnetwork: Glucocorticoid biosynthesis |
Reactome Imported |
Subnetwork: Glycoprotein hormones |
Reactome Imported |
Subnetwork: Leukotriene synthesis |
Reactome Imported |
Subnetwork: Mineralocorticoid biosynthesis |
Reactome Imported |
Subnetwork: Peptide hormone biosynthesis |
Reactome Imported |
Subnetwork: Pregnenolone biosynthesis |
Reactome Imported |
Subnetwork: Prostanoid metabolism |
Reactome Imported |
Subnetwork: Regulation of thyroid hormone activity |
Reactome Imported |
Subnetwork: Serotonin and melatonin biosynthesis |
Reactome Imported |
Subnetwork: Steroid hormones |
Reactome Imported |
Subnetwork: Thyroxine biosynthesis |
Reactome Imported |
Subnetwork: Vitamin D (calciferol) metabolism |
Reactome Imported |
Influenza Infection |
Reactome Imported |
Subnetwork: Assembly of Viral Components at the Budding Site |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Entry of Influenza Virion into Host Cell via Endocytosis |
Reactome Imported |
Subnetwork: Export of Viral Ribonucleoproteins from Nucleus |
Reactome Imported |
Subnetwork: Fusion and Uncoating of the Influenza Virion |
Reactome Imported |
Subnetwork: Fusion of the Influenza Virion to the Host Cell Endosome |
Reactome Imported |
Subnetwork: Host Interactions with Influenza Factors |
Reactome Imported |
Subnetwork: Influenza Life Cycle |
Reactome Imported |
Subnetwork: Influenza Viral RNA Transcription and Replication |
Reactome Imported |
Subnetwork: Influenza Virus Induced Apoptosis |
Reactome Imported |
Subnetwork: Inhibition of Host mRNA Processing and RNA Silencing |
Reactome Imported |
Subnetwork: Inhibition of IFN-beta |
Reactome Imported |
Subnetwork: Inhibition of Interferon Synthesis |
Reactome Imported |
Subnetwork: Inhibition of PKR |
Reactome Imported |
Subnetwork: NEP/NS2 Interacts with the Cellular Export Machinery |
Reactome Imported |
Subnetwork: NS1 Mediated Effects on Host Pathways |
Reactome Imported |
Subnetwork: Packaging of Eight RNA Segments |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus |
Reactome Imported |
Subnetwork: Transport of Ribonucleoproteins into the Host Nucleus |
Reactome Imported |
Subnetwork: Uncoating of the Influenza Virion |
Reactome Imported |
Subnetwork: Viral Messenger RNA Synthesis |
Reactome Imported |
Subnetwork: Viral RNP Complexes in the Host Cell Nucleus |
Reactome Imported |
Subnetwork: Viral mRNA Translation |
Reactome Imported |
Subnetwork: Virus Assembly and Release |
Reactome Imported |
Subnetwork: cRNA Synthesis |
Reactome Imported |
Subnetwork: vRNA Synthesis |
Reactome Imported |
Subnetwork: vRNP Assembly |
Reactome Imported |
Inhibition of HSL |
Reactome Imported |
Integration of energy metabolism |
Reactome Imported |
Subnetwork: AMPK inhibits chREBP transcriptional activation activity |
Reactome Imported |
Subnetwork: ChREBP activates metabolic gene expression |
Reactome Imported |
Subnetwork: Glucagon signaling in metabolic regulation |
Reactome Imported |
Subnetwork: Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
Reactome Imported |
Subnetwork: Insulin effects increased synthesis of Xylulose-5-Phosphate |
Reactome Imported |
Subnetwork: PKA activation in glucagon signalling |
Reactome Imported |
Subnetwork: PKA-mediated phosphorylation of key metabolic factors |
Reactome Imported |
Subnetwork: PP2A-mediated dephosphorylation of key metabolic factors |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Acetylcholine |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Fatty Acids Bound to GPR40 (FFAR1) |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Free Fatty Acids |
Reactome Imported |
Subnetwork: Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
Reactome Imported |
Integrin cell surface interactions |
Reactome Imported |
Subnetwork: Grb2:SOS provides linkage to MAPK signaling for Intergrins |
Reactome Imported |
Subnetwork: Integrin alphaIIbbeta3 signaling |
Reactome Imported |
Subnetwork: p130Cas linkage to MAPK signaling for integrins |
Reactome Imported |
Membrane Trafficking |
Reactome Imported |
Subnetwork: COPI Mediated Transport |
Reactome Imported |
Subnetwork: COPII (Coat Protein 2) Mediated Vesicle Transport |
Reactome Imported |
Subnetwork: Clathrin derived vesicle budding |
Reactome Imported |
Subnetwork: ER to Golgi Transport |
Reactome Imported |
Subnetwork: Formation of annular gap junctions |
Reactome Imported |
Subnetwork: Gap junction assembly |
Reactome Imported |
Subnetwork: Gap junction degradation |
Reactome Imported |
Subnetwork: Gap junction trafficking |
Reactome Imported |
Subnetwork: Gap junction trafficking and regulation |
Reactome Imported |
Subnetwork: Golgi Associated Vesicle Biogenesis |
Reactome Imported |
Subnetwork: Golgi to ER Retrograde Transport |
Reactome Imported |
Subnetwork: Lysosome Vesicle Biogenesis |
Reactome Imported |
Subnetwork: Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane |
Reactome Imported |
Subnetwork: Oligomerization of connexins into connexons |
Reactome Imported |
Subnetwork: Regulation of gap junction activity |
Reactome Imported |
Subnetwork: Transport of connexins along the secretory pathway |
Reactome Imported |
Subnetwork: Transport of connexons to the plasma membrane |
Reactome Imported |
Subnetwork: c-src mediated regulation of Cx43 function and closure of gap junctions |
Reactome Imported |
Subnetwork: trans-Golgi Network Vesicle Budding |
Reactome Imported |
Metabolism of RNA |
Reactome Imported |
Subnetwork: Deadenylation of mRNA |
Reactome Imported |
Subnetwork: Deadenylation-dependent mRNA decay |
Reactome Imported |
Subnetwork: Metabolism of mRNA |
Reactome Imported |
Subnetwork: Metabolism of non-coding RNA |
Reactome Imported |
Subnetwork: mRNA Decay by 3' to 5' Exoribonuclease |
Reactome Imported |
Subnetwork: mRNA Decay by 5' to 3' Exoribonuclease |
Reactome Imported |
Subnetwork: snRNP Assembly |
Reactome Imported |
Metabolism of amino acids and derivatives |
Reactome Imported |
Subnetwork: Agmatine biosynthesis |
Reactome Imported |
Subnetwork: Amine-derived hormones |
Reactome Imported |
Subnetwork: Amino acid synthesis and interconversion (transamination) |
Reactome Imported |
Subnetwork: Amino acid transport across the plasma membrane |
Reactome Imported |
Subnetwork: Branched-chain amino acid catabolism |
Reactome Imported |
Subnetwork: Carnitine synthesis |
Reactome Imported |
Subnetwork: Catecholamine biosynthesis |
Reactome Imported |
Subnetwork: Creatine metabolism |
Reactome Imported |
Subnetwork: Glycoprotein hormones |
Reactome Imported |
Subnetwork: Glyoxylate metabolism |
Reactome Imported |
Subnetwork: Histidine catabolism |
Reactome Imported |
Subnetwork: Interconversion of polyamines |
Reactome Imported |
Subnetwork: Lysine catabolism |
Reactome Imported |
Subnetwork: Metabolism of polyamines |
Reactome Imported |
Subnetwork: Peptide hormone biosynthesis |
Reactome Imported |
Subnetwork: Phenylalanine and tyrosine catabolism |
Reactome Imported |
Subnetwork: Proline catabolism |
Reactome Imported |
Subnetwork: Regulation of ornithine decarboxylase (ODC) |
Reactome Imported |
Subnetwork: Regulation of thyroid hormone activity |
Reactome Imported |
Subnetwork: Serotonin and melatonin biosynthesis |
Reactome Imported |
Subnetwork: Thyroxine biosynthesis |
Reactome Imported |
Subnetwork: Tryptophan catabolism |
Reactome Imported |
|
Reactome Imported |
Metabolism of carbohydrates |
Reactome Imported |
Subnetwork: 5-Phosphoribose 1-diphosphate biosynthesis |
Reactome Imported |
Subnetwork: Digestion of dietary carbohydrate |
Reactome Imported |
Subnetwork: Fructose catabolism |
Reactome Imported |
Subnetwork: Galactose catabolism |
Reactome Imported |
Subnetwork: Gluconeogenesis |
Reactome Imported |
Subnetwork: Glucose metabolism |
Reactome Imported |
Subnetwork: Glucose transport |
Reactome Imported |
Subnetwork: Glycogen breakdown (glycogenolysis) |
Reactome Imported |
Subnetwork: Glycogen synthesis |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Hexose transport |
Reactome Imported |
Subnetwork: Pentose phosphate pathway (hexose monophosphate shunt) |
Reactome Imported |
Subnetwork: Regulation of Glucokinase by Glucokinase Regulatory Protein |
Reactome Imported |
Metabolism of lipids and lipoproteins |
Reactome Imported |
Subnetwork: Alpha-oxidation of phytanate |
Reactome Imported |
Subnetwork: Androgen biosynthesis |
Reactome Imported |
Subnetwork: Beta oxidation of butanoyl-CoA to acetyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of hexanoyl-CoA to butanoyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of myristoyl-CoA to lauroyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of octanoyl-CoA to hexanoyl-CoA |
Reactome Imported |
Subnetwork: Beta oxidation of palmitoyl-CoA to myristoyl-CoA |
Reactome Imported |
Subnetwork: Beta-oxidation of pristanoyl-CoA |
Reactome Imported |
Subnetwork: Beta-oxidation of very long chain fatty acids |
Reactome Imported |
Subnetwork: Bile acid and bile salt metabolism |
Reactome Imported |
Subnetwork: Cholesterol biosynthesis |
Reactome Imported |
Subnetwork: Chylomicron-mediated lipid transport |
Reactome Imported |
Subnetwork: Digestion of dietary lipid |
Reactome Imported |
Subnetwork: Estrogen biosynthesis |
Reactome Imported |
Subnetwork: Fatty Acyl-CoA Biosynthesis |
Reactome Imported |
Subnetwork: Fatty acid, triacylglycerol, and ketone body metabolism |
Reactome Imported |
Subnetwork: Formation of Acetoacetic Acid |
Reactome Imported |
Subnetwork: Glucocorticoid biosynthesis |
Reactome Imported |
Subnetwork: HDL-mediated lipid transport |
Reactome Imported |
Subnetwork: Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
Reactome Imported |
Subnetwork: Import of palmitoyl-CoA into the mitochondrial matrix |
Reactome Imported |
Subnetwork: Ketone body metabolism |
Reactome Imported |
Subnetwork: LDL-mediated lipid transport |
Reactome Imported |
Subnetwork: Leukotriene synthesis |
Reactome Imported |
Subnetwork: Lipid digestion, mobilization, and transport |
Reactome Imported |
Subnetwork: Lipoprotein metabolism |
Reactome Imported |
Subnetwork: Metabolism of steroid hormones and vitamin D |
Reactome Imported |
Subnetwork: Mineralocorticoid biosynthesis |
Reactome Imported |
Subnetwork: Mitochondrial Fatty Acid Beta-Oxidation |
Reactome Imported |
Subnetwork: NADPH regeneration |
Reactome Imported |
Subnetwork: Peroxisomal lipid metabolism |
Reactome Imported |
Subnetwork: Plasmalogen biosynthesis |
Reactome Imported |
Subnetwork: Pregnenolone biosynthesis |
Reactome Imported |
Subnetwork: Propionyl-CoA catabolism |
Reactome Imported |
Subnetwork: Prostanoid metabolism |
Reactome Imported |
Subnetwork: Recycling of bile acids and salts |
Reactome Imported |
Subnetwork: Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) |
Reactome Imported |
Subnetwork: Sphingolipid metabolism |
Reactome Imported |
Subnetwork: Synthesis of Ketone Bodies |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts via 27-hydroxycholesterol |
Reactome Imported |
Subnetwork: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
Reactome Imported |
Subnetwork: Synthesis of very long-chain fatty acyl-CoAs |
Reactome Imported |
Subnetwork: Trafficking of dietary sterols |
Reactome Imported |
Subnetwork: Triglyceride Biosynthesis |
Reactome Imported |
Subnetwork: Utilization of Ketone Bodies |
Reactome Imported |
Subnetwork: Vitamin D (calciferol) metabolism |
Reactome Imported |
Subnetwork: mitochondrial fatty acid beta-oxidation of saturated fatty acids |
Reactome Imported |
Subnetwork: mitochondrial fatty acid beta-oxidation of unsaturated fatty acids |
Reactome Imported |
Metabolism of nitric oxide |
Reactome Imported |
Subnetwork: NOSIP mediated eNOS trafficking |
Reactome Imported |
Subnetwork: NOSTRIN mediated eNOS trafficking |
Reactome Imported |
Subnetwork: eNOS activation |
Reactome Imported |
Subnetwork: eNOS activation and regulation |
Reactome Imported |
Metabolism of nucleotides |
Reactome Imported |
Subnetwork: Purine catabolism |
Reactome Imported |
Subnetwork: Purine metabolism |
Reactome Imported |
Subnetwork: Purine ribonucleoside monophosphate biosynthesis |
Reactome Imported |
Subnetwork: Purine salvage |
Reactome Imported |
Subnetwork: Pyrimidine biosynthesis |
Reactome Imported |
Subnetwork: Pyrimidine catabolism |
Reactome Imported |
Subnetwork: Pyrimidine metabolism |
Reactome Imported |
Subnetwork: Pyrimidine salvage reactions |
Reactome Imported |
Subnetwork: Synthesis and interconversion of nucleotide di- and triphosphates |
Reactome Imported |
Subnetwork: Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane |
Reactome Imported |
Metabolism of porphyrins |
Reactome Imported |
Subnetwork: Heme biosynthesis |
Reactome Imported |
Subnetwork: Heme degradation |
Reactome Imported |
Metabolism of proteins |
Reactome Imported |
Subnetwork: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
Reactome Imported |
Subnetwork: Association of TriC/CCT with target proteins during biosynthesis |
Reactome Imported |
Subnetwork: Attachment of GPI anchor to uPAR |
Reactome Imported |
Subnetwork: Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
Reactome Imported |
Subnetwork: Cap-dependent Translation Initiation |
Reactome Imported |
Subnetwork: Chaperonin-mediated protein folding |
Reactome Imported |
Subnetwork: Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding |
Reactome Imported |
Subnetwork: Eukaryotic Translation Elongation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Initiation |
Reactome Imported |
Subnetwork: Eukaryotic Translation Termination |
Reactome Imported |
Subnetwork: Folding of actin by CCT/TriC |
Reactome Imported |
Subnetwork: Formation of a pool of free 40S subunits |
Reactome Imported |
Subnetwork: Formation of the ternary complex, and subsequently, the 43S complex |
Reactome Imported |
Subnetwork: Formation of tubulin folding intermediates by CCT/TriC |
Reactome Imported |
Subnetwork: GTP hydrolysis and joining of the 60S ribosomal subunit |
Reactome Imported |
Subnetwork: Gamma-carboxylation of protein precursors |
Reactome Imported |
Subnetwork: Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
Reactome Imported |
Subnetwork: Hypusine synthesis from eIF5A-lysine |
Reactome Imported |
Subnetwork: L13a-mediated translational silencing of Ceruloplasmin expression |
Reactome Imported |
Subnetwork: N-linked glycosylation |
Reactome Imported |
Subnetwork: Peptide chain elongation |
Reactome Imported |
Subnetwork: Post-chaperonin tubulin folding pathway |
Reactome Imported |
Subnetwork: Post-translational modification: gamma carboxylation and hypusine formation |
Reactome Imported |
Subnetwork: Post-translational modification: synthesis of GPI-anchored proteins |
Reactome Imported |
Subnetwork: Post-translational protein modification |
Reactome Imported |
Subnetwork: Prefoldin mediated transfer of substrate to CCT/TriC |
Reactome Imported |
Subnetwork: Protein folding |
Reactome Imported |
Subnetwork: Recycling of eIF2:GDP |
Reactome Imported |
Subnetwork: Removal of aminoterminal propeptides from gamma-carboxylated proteins |
Reactome Imported |
Subnetwork: Ribosomal scanning and start codon recognition |
Reactome Imported |
Subnetwork: Synthesis of Dolichyl-phosphate |
Reactome Imported |
Subnetwork: Synthesis of GDP-mannose |
Reactome Imported |
Subnetwork: Synthesis of UDP-N-acetyl-glucosamine |
Reactome Imported |
Subnetwork: Synthesis of dolichol-phosphate mannose |
Reactome Imported |
Subnetwork: Synthesis of dolichyl-phosphate-glucose |
Reactome Imported |
Subnetwork: Synthesis of glycosylphosphatidylinositol (GPI) |
Reactome Imported |
Subnetwork: Synthesis of substrates in N-glycan biosythesis |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Translation initiation complex formation |
Reactome Imported |
Subnetwork: Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus |
Reactome Imported |
Metabolism of vitamins and cofactors |
Reactome Imported |
Subnetwork: Biotin metabolism |
Reactome Imported |
Subnetwork: Coenzyme A biosynthesis |
Reactome Imported |
Subnetwork: Metabolism of folate and pterines |
Reactome Imported |
Subnetwork: Metabolism of water-soluble vitamins and cofactors |
Reactome Imported |
Subnetwork: Nicotinamide salvaging |
Reactome Imported |
Subnetwork: Nicotinate metabolism |
Reactome Imported |
Subnetwork: Vitamin B1 (thiamin) metabolism |
Reactome Imported |
Subnetwork: Vitamin B2 (riboflavin) metabolism |
Reactome Imported |
Subnetwork: Vitamin B5 (pantothenate) metabolism |
Reactome Imported |
Subnetwork: Vitamin C (ascorbate) metabolism |
Reactome Imported |
Subnetwork: Vitamin D (calciferol) metabolism |
Reactome Imported |
Muscle contraction |
Reactome Imported |
Subnetwork: Smooth Muscle Contraction |
Reactome Imported |
Subnetwork: Striated Muscle Contraction |
Reactome Imported |
Myogenesis |
Reactome Imported |
Subnetwork: CDO in myogenesis |
Reactome Imported |
Opioid Signalling |
Reactome Imported |
Subnetwork: Adenylate cyclase activating pathway |
Reactome Imported |
Subnetwork: Adenylate cyclase inhibitory pathway |
Reactome Imported |
Subnetwork: Ca-dependent events |
Reactome Imported |
|
Reactome Imported |
Subnetwork: CaMK IV-mediated phosphorylation of CREB |
Reactome Imported |
Subnetwork: Calmodulin induced events |
Reactome Imported |
Subnetwork: Cam-PDE 1 activation |
Reactome Imported |
Subnetwork: DARPP-32 events |
Reactome Imported |
Subnetwork: G-protein activation |
Reactome Imported |
Subnetwork: G-protein mediated events |
Reactome Imported |
Subnetwork: PKA activation |
Reactome Imported |
Subnetwork: PKA-mediated phosphorylation of CREB |
Reactome Imported |
Subnetwork: PLC beta mediated events |
Reactome Imported |
Subnetwork: phospho-PLA2 pathway |
Reactome Imported |
PLC-mediated hydrolysis of PIP2 |
Reactome Imported |
Pausing and recovery of elongation |
Reactome Imported |
Post-Elongation Processing of the Transcript |
Reactome Imported |
Subnetwork: Post-Elongation Processing of Intron-Containing pre-mRNA |
Reactome Imported |
Subnetwork: Post-Elongation Processing of Intronless pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped Intronless Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Intronless Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP independent Processing of Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: mRNA 3'-end processing |
Reactome Imported |
Pyrophosphate hydrolysis |
Reactome Imported |
Pyruvate metabolism and Citric Acid (TCA) cycle |
Reactome Imported |
Subnetwork: Citric acid cycle (TCA cycle) |
Reactome Imported |
Subnetwork: Pyruvate metabolism |
Reactome Imported |
Subnetwork: Regulation of pyruvate dehydrogenase (PDH) complex |
Reactome Imported |
Regulation of activated PAK-2p34 by proteasome mediated degradation |
Reactome Imported |
Regulation of beta-cell development |
Reactome Imported |
Subnetwork: AKT-mediated inactivation of FOXO1A |
Reactome Imported |
Subnetwork: Regulation of gene expression in beta cells |
Reactome Imported |
Subnetwork: Regulation of gene expression in early pancreatic precursor cells |
Reactome Imported |
Subnetwork: Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells |
Reactome Imported |
Subnetwork: Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells |
Reactome Imported |
Regulatory RNA pathways |
Reactome Imported |
Subnetwork: MicroRNA (miRNA) Biogenesis |
Reactome Imported |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
Reactome Imported |
Subnetwork: Formation of ATP by chemiosmotic coupling |
Reactome Imported |
Subnetwork: Mitochondrial Uncoupling Proteins |
Reactome Imported |
Subnetwork: Respiratory electron transport |
Reactome Imported |
Subnetwork: The fatty acid cycling model |
Reactome Imported |
Subnetwork: The proton buffering model |
Reactome Imported |
Signaling by BMP |
Reactome Imported |
Signaling by EGFR |
Reactome Imported |
Subnetwork: EGFR downregulation |
Reactome Imported |
Subnetwork: EGFR interacts with phospholipase C-gamma |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: Gab1 signalosome |
Reactome Imported |
Subnetwork: Grb2 events in EGFR signaling |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Subnetwork: Shc events in EGFR signaling |
Reactome Imported |
Signaling by FGFR |
Reactome Imported |
Subnetwork: Downstream signaling of activated FGFR |
Reactome Imported |
Subnetwork: FGFR ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1 ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1b ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1c and Klotho ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR1c ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR2 ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR2b ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR2c ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR3 ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR3b ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR3c ligand binding and activation |
Reactome Imported |
Subnetwork: FGFR4 ligand binding and activation |
Reactome Imported |
Subnetwork: FRS2-mediated cascade |
Reactome Imported |
Subnetwork: PI-3K cascade |
Reactome Imported |
Subnetwork: Phospholipase C-mediated cascade |
Reactome Imported |
Subnetwork: SHC-mediated cascade |
Reactome Imported |
Signaling by GPCR |
Reactome Imported |
Subnetwork: Adenosine P1 receptors |
Reactome Imported |
Subnetwork: Adrenoceptors |
Reactome Imported |
Subnetwork: Amine ligand-binding receptors |
Reactome Imported |
Subnetwork: Arachidonate production from DAG |
Reactome Imported |
Subnetwork: Calcitonin-like ligand receptors |
Reactome Imported |
Subnetwork: Chemokine receptors bind chemokines |
Reactome Imported |
Subnetwork: Class A/1 (Rhodopsin-like receptors) |
Reactome Imported |
Subnetwork: Class B/2 (Secretin family receptors) |
Reactome Imported |
Subnetwork: Class C/3 (Metabotropic glutamate/pheromone receptors) |
Reactome Imported |
Subnetwork: Dopamine receptors |
Reactome Imported |
Subnetwork: Effects of PIP2 hydrolysis |
Reactome Imported |
Subnetwork: Eicosanoid ligand-binding receptors |
Reactome Imported |
Subnetwork: Formyl peptide receptors bind formyl peptides and many other ligands |
Reactome Imported |
Subnetwork: Free fatty acid receptors |
Reactome Imported |
Subnetwork: G alpha (12/13) signalling events |
Reactome Imported |
Subnetwork: G alpha (i) signalling events |
Reactome Imported |
Subnetwork: G alpha (q) signalling events |
Reactome Imported |
Subnetwork: G alpha (s) signalling events |
Reactome Imported |
Subnetwork: G alpha (z) signalling events |
Reactome Imported |
Subnetwork: G beta:gamma signalling through PI3Kgamma |
Reactome Imported |
Subnetwork: G beta:gamma signalling through PLC beta |
Reactome Imported |
Subnetwork: G-protein beta:gamma signalling |
Reactome Imported |
Subnetwork: GPCR downstream signaling |
Reactome Imported |
Subnetwork: GPCR ligand binding |
Reactome Imported |
Subnetwork: Glucagon-type ligand receptors |
Reactome Imported |
Subnetwork: Histamine receptors |
Reactome Imported |
Subnetwork: Hormone ligand-binding receptors |
Reactome Imported |
Subnetwork: Leukotriene receptors |
Reactome Imported |
Subnetwork: Lysosphingolipid and LPA receptors |
Reactome Imported |
Subnetwork: Muscarinic acetylcholine receptors |
Reactome Imported |
Subnetwork: Nucleotide-like (purinergic) receptors |
Reactome Imported |
Subnetwork: Olfactory Signaling Pathway |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Orexin and neuropeptides FF and QRFP bind to their respective receptors |
Reactome Imported |
Subnetwork: P2Y receptors |
Reactome Imported |
Subnetwork: Peptide ligand-binding receptors |
Reactome Imported |
Subnetwork: Prostanoid ligand receptors |
Reactome Imported |
Subnetwork: Relaxin receptors |
Reactome Imported |
Subnetwork: Serotonin receptors |
Reactome Imported |
Subnetwork: Tachykinin receptors bind tachykinins |
Reactome Imported |
Subnetwork: Vasopressin-like receptors |
Reactome Imported |
Signaling by Insulin receptor |
Reactome Imported |
Subnetwork: Activation of PKB |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: Energy dependent regulation of mTOR by LKB1-AMPK |
Reactome Imported |
Subnetwork: IRS activation |
Reactome Imported |
Subnetwork: IRS-mediated signalling |
Reactome Imported |
Subnetwork: IRS-related events |
Reactome Imported |
Subnetwork: Inhibition of TSC complex formation by PKB |
Reactome Imported |
Subnetwork: Insulin receptor recycling |
Reactome Imported |
Subnetwork: Insulin receptor signalling cascade |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: PDE3B signalling |
Reactome Imported |
|
Reactome Imported |
Subnetwork: PKB-mediated events |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Subnetwork: Regulation of AMPK activity via LKB1 |
Reactome Imported |
Subnetwork: Regulation of Rheb GTPase activity by AMPK |
Reactome Imported |
Subnetwork: Release of eIF4E |
Reactome Imported |
Subnetwork: S6K1 signalling |
Reactome Imported |
Subnetwork: S6K1-mediated signalling |
Reactome Imported |
Subnetwork: SHC activation |
Reactome Imported |
Subnetwork: SHC-mediated signalling |
Reactome Imported |
Subnetwork: SHC-related events |
Reactome Imported |
Subnetwork: SOS-mediated signalling |
Reactome Imported |
Subnetwork: Signal attenuation |
Reactome Imported |
Subnetwork: mTOR signalling |
Reactome Imported |
Subnetwork: mTORC1-mediated signalling |
Reactome Imported |
Signaling by Notch |
Reactome Imported |
Subnetwork: A third proteolytic cleavage releases NICD |
Reactome Imported |
Subnetwork: Maturation of Notch precursor via proteolytic cleavage |
Reactome Imported |
Subnetwork: Mature Notch receptor trafficks to plasma membrane |
Reactome Imported |
Subnetwork: NICD trafficks to nucleus |
Reactome Imported |
Subnetwork: Notch receptor binds with a ligand |
Reactome Imported |
Subnetwork: Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
Reactome Imported |
Subnetwork: Transport of Notch receptor precursor to golgi |
Reactome Imported |
Signaling by PDGF |
Reactome Imported |
Subnetwork: Down-stream signal transduction |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Signaling by Rho GTPases |
Reactome Imported |
Subnetwork: Rho GTPase cycle |
Reactome Imported |
Signaling by TGF beta |
Reactome Imported |
Signaling by VEGF |
Reactome Imported |
Subnetwork: Neurophilin interactions with VEGF and VEGFR |
Reactome Imported |
Subnetwork: VEGF binds to VEGFR leading to receptor dimerization |
Reactome Imported |
Subnetwork: VEGF ligand-receptor interactions |
Reactome Imported |
Signaling by Wnt |
Reactome Imported |
Subnetwork: Beta-catenin phosphorylation cascade |
Reactome Imported |
Subnetwork: Degradation of beta-catenin by the destruction complex |
Reactome Imported |
Signaling in Immune system |
Reactome Imported |
Subnetwork: Activated TLR4 signalling |
Reactome Imported |
Subnetwork: Activation of C3 and C5 |
Reactome Imported |
Subnetwork: Activation of the AP-1 family of transcription factors |
Reactome Imported |
Subnetwork: Alternative complement activation |
Reactome Imported |
Subnetwork: CD28 co-stimulation |
Reactome Imported |
Subnetwork: CD28 dependent PI3K/Akt signaling |
Reactome Imported |
Subnetwork: CD28 dependent Vav1 pathway |
Reactome Imported |
Subnetwork: CREB phosphorylation |
Reactome Imported |
Subnetwork: CTLA4 inhibitory signaling |
Reactome Imported |
Subnetwork: Classical antibody-mediated complement activation |
Reactome Imported |
Subnetwork: Complement cascade |
Reactome Imported |
Subnetwork: Costimulation by the CD28 family |
Reactome Imported |
Subnetwork: Creation of C4 and C2 activators |
Reactome Imported |
Subnetwork: Downstream TCR signaling |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK/MAPK targets |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: ERKs are inactivated |
Reactome Imported |
Subnetwork: Generation of second messenger molecules |
Reactome Imported |
Subnetwork: Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
Reactome Imported |
Subnetwork: Initial triggering of complement |
Reactome Imported |
Subnetwork: Innate Immunity Signaling |
Reactome Imported |
Subnetwork: Interleukin-1 signaling |
Reactome Imported |
Subnetwork: JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
Reactome Imported |
Subnetwork: LPS transferred from LBP carrier to CD14 |
Reactome Imported |
Subnetwork: Lectin pathway of complement activation |
Reactome Imported |
Subnetwork: MAP kinases activation in TLR cascade |
Reactome Imported |
Subnetwork: MAPK targets/ Nuclear events mediated by MAP kinases |
Reactome Imported |
Subnetwork: MyD88 cascade |
Reactome Imported |
Subnetwork: PD-1 signaling |
Reactome Imported |
Subnetwork: Phosphorylation of CD3 and TCR zeta chains |
Reactome Imported |
Subnetwork: Signaling by Interleukins |
Reactome Imported |
Subnetwork: TCR signaling |
Reactome Imported |
Subnetwork: TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade |
Reactome Imported |
|
Reactome Imported |
Subnetwork: Terminal pathway of complement |
Reactome Imported |
Subnetwork: Toll Like Receptor 10 (TLR10) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 2 Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 3 (TLR3) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 4 (TLR4) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 5 (TLR5) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 7/8 (TLR7/8) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor 9 (TLR9) Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor TLR1:TLR2 Cascade |
Reactome Imported |
Subnetwork: Toll Like Receptor TLR6:TLR2 Cascade |
Reactome Imported |
Subnetwork: Toll Receptor Cascades |
Reactome Imported |
Subnetwork: Translocation of ZAP-70 to Immunological synapse |
Reactome Imported |
Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates RIP1 |
Reactome Imported |
Subnetwork: Viral dsRNA:TLR3:TRIF Complex Activates TBK1/IKK epsilon |
Reactome Imported |
Subnetwork: activated TAK1 mediates p38 MAPK activation |
Reactome Imported |
Subnetwork: human TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
Reactome Imported |
Signalling by NGF |
Reactome Imported |
Subnetwork: AKT phosphorylates targets in the cytosol |
Reactome Imported |
Subnetwork: AKT phosphorylates targets in the nucleus |
Reactome Imported |
Subnetwork: ARMS-mediated activation |
Reactome Imported |
Subnetwork: Activation of TRKA receptors |
Reactome Imported |
Subnetwork: Axonal growth inhibition (RHOA activation) |
Reactome Imported |
Subnetwork: Axonal growth stimulation |
Reactome Imported |
Subnetwork: CREB phosphorylation |
Reactome Imported |
|
Reactome Imported |
Subnetwork: CaMK IV-mediated phosphorylation of CREB |
Reactome Imported |
Subnetwork: Calmodulin induced events |
Reactome Imported |
Subnetwork: Cam-PDE 1 activation |
Reactome Imported |
Subnetwork: Cell death signalling via NRAGE, NRIF and NADE |
Reactome Imported |
Subnetwork: Ceramide signalling |
Reactome Imported |
Subnetwork: ERK activation |
Reactome Imported |
Subnetwork: ERK/MAPK targets |
Reactome Imported |
Subnetwork: ERK1 activation |
Reactome Imported |
Subnetwork: ERK2 activation |
Reactome Imported |
Subnetwork: ERKs are inactivated |
Reactome Imported |
Subnetwork: Frs2-mediated activation |
Reactome Imported |
Subnetwork: MAP kinase cascade |
Reactome Imported |
Subnetwork: MEK activation |
Reactome Imported |
Subnetwork: NADE modulates death signalling |
Reactome Imported |
Subnetwork: NF-kB is activated and signals survival |
Reactome Imported |
Subnetwork: NFG and proNGF binds to p75NTR |
Reactome Imported |
Subnetwork: NGF processing |
Reactome Imported |
Subnetwork: NGF signalling via TRKA from the plasma membrane |
Reactome Imported |
Subnetwork: NGF-independant TRKA activation |
Reactome Imported |
Subnetwork: NRAGE signals death through JNK |
Reactome Imported |
Subnetwork: NRIF signals cell death from the nucleus |
Reactome Imported |
Subnetwork: Negative regulation of the PI3K/AKT network |
Reactome Imported |
Subnetwork: Nuclear Events (kinase and transcription factor activation) |
Reactome Imported |
Subnetwork: PI3K/AKT signalling |
Reactome Imported |
Subnetwork: PKA activation |
Reactome Imported |
Subnetwork: PKA-mediated phosphorylation of CREB |
Reactome Imported |
Subnetwork: PLC-gamma1 signalling |
Reactome Imported |
Subnetwork: Prolonged ERK activation events |
Reactome Imported |
Subnetwork: RAF activation |
Reactome Imported |
Subnetwork: RAF phosphorylates MEK |
Reactome Imported |
Subnetwork: Regulated proteolysis of p75NTR |
Reactome Imported |
Subnetwork: Retrograde neurotrophin signalling |
Reactome Imported |
Subnetwork: Signalling to ERK5 |
Reactome Imported |
Subnetwork: Signalling to ERKs |
Reactome Imported |
Subnetwork: Signalling to RAS |
Reactome Imported |
Subnetwork: Signalling to STAT3 |
Reactome Imported |
Subnetwork: Signalling to p38 via RIT and RIN |
Reactome Imported |
Subnetwork: TRKA activation by NGF |
Reactome Imported |
Subnetwork: p38MAPK events |
Reactome Imported |
Subnetwork: p75 NTR receptor-mediated signalling |
Reactome Imported |
Subnetwork: p75NTR negatively regulates cell cycle via SC1 |
Reactome Imported |
Subnetwork: p75NTR recruits signalling complexes |
Reactome Imported |
Subnetwork: p75NTR regulates axonogenesis |
Reactome Imported |
Subnetwork: p75NTR signals via NF-kB |
Reactome Imported |
Synaptic Transmission |
Reactome Imported |
Subnetwork: Acetylcholine Binding And Downstream Events |
Reactome Imported |
Subnetwork: Acetylcholine Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Activation of AMPA receptors |
Reactome Imported |
Subnetwork: Activation of Ca-permeable Kainate Receptor |
Reactome Imported |
Subnetwork: Activation of CaMK IV |
Reactome Imported |
Subnetwork: Activation of Kainate Receptors upon glutamate binding |
Reactome Imported |
Subnetwork: Activation of NMDA receptor upon glutamate binding and postsynaptic events |
Reactome Imported |
Subnetwork: Activation of Na-permeable Kainate Receptors |
Reactome Imported |
Subnetwork: Activation of Nicotinic Acetylcholine Receptors |
Reactome Imported |
Subnetwork: Astrocytic Glutamate-Glutamine Uptake And Metabolism |
Reactome Imported |
Subnetwork: CREB phophorylation through the activation of Ras |
Reactome Imported |
Subnetwork: CREB phosphorylation through the activation of Adenylate Cyclase |
Reactome Imported |
Subnetwork: CREB phosphorylation through the activation of CaMKII |
Reactome Imported |
Subnetwork: CREB phosphorylation through the activation of CaMKK |
Reactome Imported |
Subnetwork: Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels |
Reactome Imported |
Subnetwork: Dopamine Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Dopamine clearance from the synaptic cleft |
Reactome Imported |
Subnetwork: Electric Transmission Across Gap Junctions |
Reactome Imported |
Subnetwork: Enzymatic degradation of Dopamine by monoamine oxidase |
Reactome Imported |
Subnetwork: Enzymatic degradation of dopamine by COMT |
Reactome Imported |
Subnetwork: Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity |
Reactome Imported |
Subnetwork: Glutamate Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Highly calcium permeable nicotinic acetylcholine receptors |
Reactome Imported |
Subnetwork: Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
Reactome Imported |
Subnetwork: Highly sodium permeable acetylcholine nicotinic receptors |
Reactome Imported |
Subnetwork: Ionotropic activity of Kainate Receptors |
Reactome Imported |
Subnetwork: Metabolism of serotonin |
Reactome Imported |
Subnetwork: Neuroransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell |
Reactome Imported |
Subnetwork: Neurotransmitter Clearance In The Synaptic Cleft |
Reactome Imported |
Subnetwork: Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Neurotransmitter uptake and Metabolism In Glial Cells |
Reactome Imported |
Subnetwork: Norepinephrine Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Post NMDA receptor activation events |
Reactome Imported |
Subnetwork: Postsynaptic nicotinic acetylcholine receptors |
Reactome Imported |
Subnetwork: Presynaptic function of Kainate receptors |
Reactome Imported |
Subnetwork: Presynaptic nicotinic acetylcholine receptors |
Reactome Imported |
Subnetwork: RSK activation |
Reactome Imported |
Subnetwork: Ras activation uopn Ca2+ infux through NMDA receptor |
Reactome Imported |
Subnetwork: Serotonin Neurotransmitter Release Cycle |
Reactome Imported |
Subnetwork: Serotonin clearance from the synaptic cleft |
Reactome Imported |
Subnetwork: Synthesis of Dopamine |
Reactome Imported |
Subnetwork: Trafficking of AMPA receptors |
Reactome Imported |
Subnetwork: Trafficking of GluR2-containing AMPA receptors |
Reactome Imported |
Subnetwork: Transmission across Chemical Synapses |
Reactome Imported |
Subnetwork: Transmission across Electrical Synapses |
Reactome Imported |
Subnetwork: Unblocking of NMDA receptor, glutamate binding and activation |
Reactome Imported |
Transcription |
Reactome Imported |
Subnetwork: Cleavage of Growing Transcript in the Termination Region |
Reactome Imported |
Subnetwork: Formation of RNA Pol II elongation complex |
Reactome Imported |
Subnetwork: Formation of the Early Elongation Complex |
Reactome Imported |
Subnetwork: Mitochondrial transcription initiation |
Reactome Imported |
Subnetwork: Mitochondrial transcription termination |
Reactome Imported |
Subnetwork: RNA Pol II CTD phosphorylation and interaction with CE |
Reactome Imported |
Subnetwork: RNA Polymerase I Chain Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase I Promoter Clearance |
Reactome Imported |
Subnetwork: RNA Polymerase I Promoter Escape |
Reactome Imported |
Subnetwork: RNA Polymerase I Promoter Opening |
Reactome Imported |
Subnetwork: RNA Polymerase I Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase I Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase I Transcription Termination |
Reactome Imported |
Subnetwork: RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase II Pre-transcription Events |
Reactome Imported |
Subnetwork: RNA Polymerase II Promoter Escape |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Initiation And Promoter Clearance |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
Reactome Imported |
Subnetwork: RNA Polymerase II Transcription Termination |
Reactome Imported |
Subnetwork: RNA Polymerase III Abortive And Retractive Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase III Chain Elongation |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation From Type 1 Promoter |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation From Type 2 Promoter |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Initiation From Type 3 Promoter |
Reactome Imported |
Subnetwork: RNA Polymerase III Transcription Termination |
Reactome Imported |
Subnetwork: Transcription from mitochondrial promoters |
Reactome Imported |
Transmembrane transport of small molecules |
Reactome Imported |
Subnetwork: ABC-family proteins mediated transport |
Reactome Imported |
Subnetwork: Amino acid transport across the plasma membrane |
Reactome Imported |
Subnetwork: Bicarbonate transporters |
Reactome Imported |
Subnetwork: Cation-coupled Chloride cotransporters |
Reactome Imported |
Subnetwork: Class II GLUTs |
Reactome Imported |
Subnetwork: Facilitative Na+-independent glucose transporters |
Reactome Imported |
Subnetwork: Glucose transport |
Reactome Imported |
Subnetwork: Hexose transport |
Reactome Imported |
Subnetwork: Inositol transporters |
Reactome Imported |
Subnetwork: Metal ion SLC transporters |
Reactome Imported |
Subnetwork: Multifunctional anion exchangers |
Reactome Imported |
Subnetwork: Na+-dependent glucose transporters |
Reactome Imported |
Subnetwork: Na+/Cl- dependent neurotransmitter transporters |
Reactome Imported |
Subnetwork: Organic anion transport |
Reactome Imported |
Subnetwork: Organic anion transporters |
Reactome Imported |
Subnetwork: Organic cation transport |
Reactome Imported |
Subnetwork: Organic cation/anion/zwitterion transport |
Reactome Imported |
Subnetwork: Proton-coupled monocarboxylate transport |
Reactome Imported |
Subnetwork: Proton-coupled neutral amino acid transporters |
Reactome Imported |
Subnetwork: Proton/oligonucleotide cotransporters |
Reactome Imported |
Subnetwork: Regulation of Glucokinase by Glucokinase Regulatory Protein |
Reactome Imported |
Subnetwork: Rhesus glycoproteins mediate ammonium transport. |
Reactome Imported |
Subnetwork: SLC-mediated transmembrane transport |
Reactome Imported |
Subnetwork: Sodium-coupled phosphate cotransporters |
Reactome Imported |
Subnetwork: Sodium-coupled sulphate, di- and tri-carboxylate transporters |
Reactome Imported |
Subnetwork: Sodium/Calcium exchangers |
Reactome Imported |
Subnetwork: Sodium/Proton exchangers |
Reactome Imported |
Subnetwork: Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |
Reactome Imported |
Subnetwork: Transport of inorganic cations/anions and amino acids/oligopeptides |
Reactome Imported |
Subnetwork: Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane |
Reactome Imported |
Subnetwork: Transport of nucleotide sugars |
Reactome Imported |
Subnetwork: Transport of vitamins, nucleosides, and related molecules |
Reactome Imported |
Subnetwork: Type II Na+/Pi cotransporters |
Reactome Imported |
Subnetwork: Zinc efflux and compartmentalization by the SLC30 family |
Reactome Imported |
Subnetwork: Zinc influx into cells by the SLC39 gene family |
Reactome Imported |
Subnetwork: Zinc transporters |
Reactome Imported |
Xanthine formation |
Reactome Imported |
Subnetwork: Guanine formation |
Reactome Imported |
mRNA Processing |
Reactome Imported |
Subnetwork: C6 deamination of adenosine |
Reactome Imported |
Subnetwork: Formation of editosomes by ADAR proteins |
Reactome Imported |
Subnetwork: Formation of the Editosome |
Reactome Imported |
Subnetwork: Processing of Capped Intron-Containing Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped Intronless Pre-mRNA |
Reactome Imported |
Subnetwork: Processing of Capped Transcripts |
Reactome Imported |
Subnetwork: Processing of Intronless Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: SLBP independent Processing of Histone Pre-mRNAs |
Reactome Imported |
Subnetwork: Transport of Mature Transcript to Cytoplasm |
Reactome Imported |
Subnetwork: Transport of Mature mRNA Derived from an Intronless Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNA derived from an Intron-Containing Transcript |
Reactome Imported |
Subnetwork: Transport of Mature mRNAs Derived from Intronless Transcripts |
Reactome Imported |
Subnetwork: Transport of the SLBP Dependant Mature mRNA |
Reactome Imported |
Subnetwork: Transport of the SLBP independent Mature mRNA |
Reactome Imported |
Subnetwork: mRNA 3'-end processing |
Reactome Imported |
|
Reactome Imported |
|
Reactome Imported |
Subnetwork: mRNA Editing: A to I Conversion |
Reactome Imported |
Subnetwork: mRNA Editing: C to U Conversion |
Reactome Imported |
Subnetwork: mRNA Splicing |
Reactome Imported |
Subnetwork: mRNA Splicing - Major Pathway |
Reactome Imported |
Subnetwork: mRNA Splicing - Minor Pathway |
Reactome Imported |