Interagency Deliberations

Cal/EPA Emergent Chemical (DOC)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Letter Cal/EPA Emergent Chemicals Sources (DOC)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Cal/EPA to ADUSD(E) (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Ms. Cantu, SWRCB (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

CDC testimony (DOC)

Testimonies offered at House Energy and Commerce Hearing April 25, 2007
 

Cover Letter 19 February 2002 (DOC)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

DoD Comments on the U.S. Environmental Protection Agency's Draft Perchlorate Environmental Contamination:Toxicological Review and Risk Characterization (DOC)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

DoD Extension Comments (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

DoD Extension Comments: Cover Letter (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

DuBois Letter (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Letter from Mr. Hickox (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Executive Summary (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

EPA Perchlorate Review Draft (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Woodley to Mr. Lowry (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

response (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Tamminen to Beehler (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Response Letter to Mr. Hickox (PDF)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Perchloratemcl_mwwacomments (PDF)

Letter to Dave Terry, MA DEP.  Massachusetts Waterworks opposes the 2 ppb perchlorate MCL that MA DEP is proposing.
 

Testimony and Presentations

EPA presentation (PDF)

Presentations made by DoD to the NAS panel titled Committee to Assess the Health Implications of Perchlorate Ingestion in 2003
 

EPA testimony (DOC)

Testimonies offered at House Energy and Commerce Hearing April 25, 2007
 

DoD Oral Presentations (DOC)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

GAO Testimony on Management of Perchlorate (PDF)

Testimonies offered at House Energy and Commerce Hearing April 25, 2007
 

DoD Technical Slides (PPT)

Presentations made by DoD to the NAS panel titled Committee to Assess the Health Implications of Perchlorate Ingestion in 2003
 

DoD Comments (PDF)

Presentations made by DoD to the NAS panel titled Committee to Assess the Health Implications of Perchlorate Ingestion in 2003
 

Wennerberg JSEM Present on Perchlorate (PPT)

JSEM slides from the meeting in Tampa, FL 2005
 

Braverman (PDF)

Perchlorate Human Health Effects Materials
 

Treatment, Policy and Standards

8684.pdf (PDF)

Calif.: Development of a Health-Protective Drinking Water Level for Perchlorate
 

Perchlorate in Groundwater (PDF)

Information related to various treatment technologies for perchlorate.
 

AWWA Letter (PDF)

10-09 Information on the EPA's Regulatory Determinations Regarding Contaminants on the Second Drinking Water Contaminant Candidate List Preliminary Determinations. Includes perchlorate and several other ECs.
 

Mechanisms of Perchlorate Degradation: An Overview (PDF)

Information related to various treatment technologies for perchlorate.
 

nwra lab paper (PDF)

10-09 Information on the EPA's Regulatory Determinations Regarding Contaminants on the Second Drinking Water Contaminant Candidate List Preliminary Determinations. Includes perchlorate and several other ECs.
 

NWRA Paper (PDF)

Information on the EPA's Regulatory Determinations Regarding Contaminants on the Second Drinking Water Contaminant Candidate List Preliminary Determinations. Includes perchlorate and several other ECs.
 

Perchlorate Isotope Analysis (PDF)

Study on the potential natural and man-made  sources of perchlorate in the environment.
 

PSG Letter (PDF)

10-09 Information on the EPA's Regulatory Determinations Regarding Contaminants on the Second Drinking Water Contaminant Candidate List Preliminary Determinations. Includes perchlorate and several other ECs.
 

Evaluation of the EPA Preliminary Remediation Goal (PRG) for Perchlorate (PDF)

Technical paper, Evaluation of the U.S. EPA/OSWER Preliminary Remediation Goal (PRG) for Perchlorate in Groundwater: Focus on Exposure to Nursing Infants the authors (Gary L. Ginsberg, Dale B. Hattis, R. Thomas Zoeller and Deborah C. Rice).
 

Ting et al 2006 EHP Perchlorate (PDF)

An article from the Journal Env. Health Perspectives from Ting et al that describes the basis for the Calif. public health goal of 6 ppb in water.
 

Detection and Sources

Nonpoint Sources of Perchlorate (PDF)

Study on the Nonpoint Sources of Perchlorate in the environment.
 

Natural Perchlorate Has a Unique Oxygen Isotope Signature (PDF)

Slides on perchlorate isotopic forensics (Bohlke, John Karl) (PDF)

10-09 Widespread occurrence of perchlorate has been reported in recent years in surface water bodies, ground water aquifers, and agricultural products across the U.S. This perchlorate, which may have both anthropogenic and natural sources, can be problematic because the highly soluble perchlorate anion is relatively inert and difficult to remove by conventional water treatment methods. Because several toxicological studies indicate that trace amounts of perchlorate can cause thyroid cancer and child developmental problems, there is increasing interest in characterizing acceptable contamination levels as well as the ultimate sources of perchlorate in the environment. The stable isotope ratios of Cl and O can potentially be used to distinguish the source(s) of perchlorate in a given location and to evaluate the extent of biodegradation. Several papers related to this topic are included here.
 

Slides on perchlorate isotopic forensics (Dasgupta, Purnendu K.) (PDF)

Widespread occurrence of perchlorate has been reported in recent years in surface water bodies, ground water aquifers, and agricultural products across the U.S. This perchlorate, which may have both anthropogenic and natural sources, can be problematic because the highly soluble perchlorate anion is relatively inert and difficult to remove by conventional water treatment methods. Because several toxicological studies indicate that trace amounts of perchlorate can cause thyroid cancer and child developmental problems, there is increasing interest in characterizing acceptable contamination levels as well as the ultimate sources of perchlorate in the environment. The stable isotope ratios of Cl and O can potentially be used to distinguish the source(s) of perchlorate in a given location and to evaluate the extent of biodegradation. Several papers related to this topic are included here.
 

EPA Study 2 (PDF)

EPA study on the potential natural and man-made  sources of perchlorate in the environment.
 

Perchlorate Behavior in a Municipal Lake Following Fireworks Displays (PDF)

Perchlorate salts of potassium and ammonium are the primary oxidants in pyrotechnic mixtures, yet insufficient information is available regarding the relationship between fireworks displays and the environmental occurrence of perchlorate.
 

Survey of Fertilizers and Related Materials for Perchlorate (PDF)

Information related to various treatment technologies for perchlorate.
 

Fertilizer from Chile puts perchlorate on the table (PDF)

Study on the potential natural and man-made  sources of perchlorate in the environment.
 

GAO Sampling Tracking for Perchlorate May 2005 (PDF)

GAO Reports and Letters on sampling tracking for perchlorate, May 2005.
 

Relative Source Contributions to the Food Chain for perchlorate (PDF)

Relative Source Contributions to the Food Chain for perchlorate
 

AWWA Report 2005 (PDF)

AWWA report on sources of perchlorate in the environment.
 

Propellant Residues on Ranges (PDF)

Study on the potential natural and man-made  sources of perchlorate in the environment.
 

Stable Isotopic Composition of Chlorine and Oxygen in Synthetic and Natural Perchlorate (PDF)

USGS Report (PDF)

USGS study on the potential natural and man-made  sources of perchlorate in the environment.
 

Alternative Causes of Widespread, Low Concentration Perchlorate Impacts to Groundwater (PDF)

A report on Alternative Causes of Widespread, Low Concentration Perchlorate Impacts to Groundwater, Strategic Environmental Research and Development Program (SERDP), 5 May 2005
 

Background Concentrations of Perchlorate and its Impact on Site Assessment (PDF)

A presentation entitled, Background Concentrations of Perchlorate and its Impact on Site Assessment, by Andrew Jackson, Srinath Rajagopalan, Balaji Rao, Todd Anderson, Ken Rainwater,(Water Resources Center, Texas Tech University) David Stonestrom, Lynne Fahlquist, Greta Orris (United States Geological Survey) and Greg Harvey (USAF)
 

Identification of Perchlorate Sources - Feature Presentation (PDF)

Information related to the 17 April 2007 MERIT Information Exchange Meeting.
 

JSEM_ClareMendelsohn_Final (PPT)

JSEM slides from the meeting in Tampa, FL 2005
 

Perchlorate Fingerprinting RPM News 5 2 2007 (DOC)

Historical correspondence within DoD and between DoD and other federal agencies and states related to perchlorate.
 

Health and Ecological Effects

ATSDR Staff Report on Genetic Factors and Perchlorate (PDF)

Genetic Factors that Might Lead to Different Responses in Individuals Exposed to Perchlorate Franco Scinicariello, H. Edward Murray, Lester Smith, Sharon Wilbur, and Bruce A. Fowler doi:10.1289/ehp.8076 (available at http://dx.doi.org/)
 

Thyroid Function in Newborns (DOC)

Perchlorate Human Health Effects Materials
 

AFIERA slides (PDF)

Ecological Effects of Perchlorate
 

smoking and perchlorate (PDF)

Perchlorate Human Health Effects Materials
 

Mechanistic Data (PDF)

Perchlorate Human Health Effects Materials
 

CDC Q and A (DOC)

This document is for use by CDC officials responding to press inquiries - however it is also useful for any DoD official that is speaking to stakeholders about perchlorate.
 

IPSC Eco Subcommittee (PDF)

Ecological Effects of Perchlorate
 

Israel Health Study (PDF)

Regulating Perchlorate CIO43 in Drinking Water: Protecting Public Health Gary Winston and Yona Amitai Departments of Environmental Health and Mother, Child, and Adolescent Health, Israel Ministry of Health, Jerusalem.
 

Newborn to Cancer (PPT)

Perchlorate Human Health Effects Materials
 

Neonatal T4 Thyroxine (PDF)

Perchlorate Human Health Effects Materials
 

Ammonium Perchlorate Workers (PDF)

Perchlorate Human Health Effects Materials
 

Oregon Draft HC (PDF)

A draft health consultation of an exposure investigation regarding perchlorate. It stems from a Health Consultation that was conducted in Oregon and released in December 2006.
 

Oregon Perchlorate EI summary (DOC)

A summary of an exposure investigation regarding perchlorate. It stems from a Health Consultation that was conducted in Oregon and released in December 2006.
 

Pathology (PDF)

Perchlorate Human Health Effects Materials
 

Perchlorate Exposure are Safe for Pregnant Women (PDF)

Perchlorate ATA News 6 Oct 2007 press release on pregnant women
 

Perchlorate Exposure of the US Population 2001 2002.pdf (PDF)

Perchlorate Exposure of the US Population
 

Perchlorate Thyroid NHANES 01-02.pdf (PDF)

Urinary Perchlorate and Thyroid Hormone Levels in Adolescent and Adult Men and Women Living in the United States
 

EPA Draft ERD (PDF)

Perchlorate Human Health Effects Materials
 

Review: Individuals respond to perchlorate differently (PDF)

Perchlorate has been detected in groundwater in many parts of the United States, and recent detection in vegetable and dairy food products indicates that contamination by perchlorate is more widespread than previously thought. Perchlorate is a competitive
 

Gaps by TERA (PPT)

Perchlorate Human Health Effects Materials
 

TERA Peer Review (PPT)

Perchlorate Human Health Effects Materials
 

Amphibian Metamorphosis (PPT)

Ecological Effects of Perchlorate
 

University of South Florida Review (DOC)

Perchlorate Human Health Effects Materials
 

Perchlorate Risk Assessment Symposium (PDF)

Agenda for Perchlorate Symposium held in conjunction with the Society of Toxicologists meeting in Seattle, Wa, the week of March 17
 

Blount NHANES perchlorate study - SOT symposium presentation (PDF)

Dr. Blount has graciously provided the presentation on good faith that it will not be misquoted or quoted out of context.  We request that anyone who receives these presentations and wishes to cite, quote or otherwise use them contact the presenter.
 

Breast Milk Iodine and Perchlorate Concentrations (PDF)

Perchlorate exposure was not significantly correlated with breast milk iodine concentrations.  Perchlorate was detectable in infant formula, but at lower levels than in breast milk.  47% of women sampled may have been providing breast milk with insufficient iodine to meet infants requirements.
 

EHP Doug Crawford-Brown (PDF)

Intersubject Variability of Risk from Perchlorate in Community Water Supplies
 

EST vitamins perchlorate (PDF)

EST article on vitamins and perchlorate
 

Biomonitoring Data on Thyroid-Active Compounds: Database and Issues Regarding (PDF)

Presentation slides from Biomonitoring Data on Thyroid-Active Compounds: Database and Issues Regarding Variability and Interpretation, by Ben Blount, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention. May 2008
 

Effect of Iodine Status and Gender on Perchlorate Inhibition of Iodine Uptake (PDF)

Powerpoint from SOT  meeting on perchlorate risk assessment.  Not for wide distribution - material will be placed in press.
 

EPA study of perchlorate impacts on brain development (PDF)

This study concludes that there is irreparable damage to brain function from developmental exposure to perchlorate.
 

FDA perchlorate total diet Study Questions and Answers (DOC)

FDA total diet study - Talking points (DOC)

Howd on Perchlorate at SOT perchlorate symposium (PDF)

Dr. Howd has graciously provided the presentation on good faith that it will not be misquoted or quoted out of context.  We request that anyone who receives these presentations and wishes to cite, quote or otherwise use them contact the presenter at the provided email addresses beforehand.
 

Lamm ppt on Perchlorate at SOT perchlorate symposium (PDF)

Dr. Lamm has graciously provided the presentation on good faith that it will not be misquoted or quoted out of context.  We request that anyone who receives these presentations and wishes to cite, quote or otherwise use them contact the presenter at the provided email addresses beforehand.
 

Society of Toxicology Perchlorate Symposium Agenda - 2008 (PDF)

Perchlorate SETAC Abstracts (PDF)

Material referenced in the EC News Letter for 15 Dec 05