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Microbial Genome NewsTIGR Sequencing Six More Microbes The DOE Microbial Genome Program (MGP) aims to determine the sequence of bacteria having potential usefulness in energy, environmental, and evolutionary research (http://www.er.doe.gov/production/ober/HELSRD_top.html). With the support of MGP, The Institute for Genomic Research (TIGR) and its collaborators are sequencing the genomes of an additional six microbes.
Tuberculosis Microbe Sequenced An estimated 2.9 million people died from this chronic infectious disease in 1997, and concern is growing over new antibiotic-resistant strains that have emerged in recent years. According to a Nature online special report on the global tuberculosis epidemic (http://www.nature.com), about one in every three people in the world is infected with M. tuberculosis, and each has an estimated 10% lifetime risk of progressing to clinical disease. Scientists hope that knowledge of the DNA sequence will provide clues to designing more effective therapeutic agents and vaccines. The sequence, reported in the June 11 issue of Nature (393, 537-44), is accessible from the Sanger Centre Web site (http://www.sanger.ac.uk/Projects/M_tuberculosis). Searching TB Genome The electronic form of the newsletter may be cited in the following
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