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Articles
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Controlling stem strength
The irregular xylem (irx) mutation in Arabidopsis collapses the stem, causing dwarfism, and can be rescued by cell-specific control of xylan expression to create viable plants with enhanced traits for biofuel production.
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Lifestyle and mental health
Felice Jacka et al. discuss new evidence from studies on diet quality and common mental disorders, and argue that depression and anxiety be ranked amongst prevalent medical conditions influenced by lifestyle, to help develop prevention strategies.
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Bipolar disorder and diabetes
There is a stronger association between the use of anti-diabetic agents and mood stabilizers in women than in men, indicating that diabetes and bipolar disorder may have shared risk pathways and women are more at risk of having both conditions.
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Innate immune response to Dengue Virus
Guanylate-binding protein 1 (GBP1), an interferon stimulated gene, was upregulated during Dengue Virus infection of macrophages. GBP1 knock-down decreased cytokine production whilst increasing virus growth. This suggests that GBP1 forms part of the anti-viral response to Dengue Virus.
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Viral defense genes in Capsicum annuum
The transcriptome of Capsicum annuum infected with the begomovirus "pepper golden mosaic virus" was compared to uninfected plants and those that had recovered from infection. 309 genes were differentially expressed including some that may be novel defense genes, and many of which are conserved in tomato and potato.
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Schizophrenia care & survival patterns
Schizophrenia is linked to excess mortality and multimorbidity; schizophrenics in the U.S. aged 50 years or over treated appropriately for their comorbidity have improved survival, highlighting the importance of guideline-concordant care.
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TransFIC: functional impact of variants
Cancer genome projects need to identify cancer-causing variants; a new method improves the assessment of the functional impact of SNVs by including the baseline tolerance of genes to mutations.
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Tissue engineering for muscular dystrophy
A novel therapeutic technique involving the delivery of mesoangioblast stem cells via a hydrogel cell-carrier matrix, is capable of producing enriched donor cell engraftment into skeletal muscle.
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Recognizing and treating rage
Episodes of rage and violence can have a devastating effect on people's lives, but are rarely mentioned by patients; David T George and colleagues recommend that physicians have an important opportunity to recognize and treat the problem.
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Biochemistry of the black dahlia
The distinctive coloration of the few black-flowered cultivars of the popular dahlia plant is the result of a dramatic increase in the accumulation of metabolites known as anthocyanins, at the expense of related chemicals called flavones.
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BioMed Central news
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Highlighting the best open access research: BioMed Central’s 7th Annual Research Awards
Nominations are now open for you to put forward your favorite BioMed Central open access research article for our seventh annual Research Awards. For more information please visit the blog.
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Companion articles to the swine genome sequence
BioMed Central’s open access journal GigaScience, BMC Genetics, BMC Biology, BMC Genomics, BMC Medical Genomics, BMC Cell Biology are proud to be part of a wider series of papers, including the pig genome sequence paper in Nature. To find out more on the collection please visit the blog.
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Extreme Physiology & Medicine publishes a 'Career Perspectives' series
Extreme Physiology & Medicine has launched a collection of personal reviews and reflections by eminent academics of their life’s work, influences and career highlights to date. Published so far are memoirs from Jim Milledge, Mike Sawka and John West.
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Open Access Africa 2012
BioMed Central’s third Open Access Africa conference was a huge success. A thematic series showcasing African research has also been published to coincide with the event. To find out more please read our blog.
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