National Select Agent Registry phone numbers for APHIS (301-851-3300) and CDC (404-718-2000).
Last Updated: Friday, June 25, 2010

About Us

In the wake of the Oklahoma City bombing of the Alfred E. Murrah Building in April 1995, Congress passed the Antiterrorism and Effective Death Penalty Act of 1996 in October 1996. The provisions of this act were implemented by 42 CFR 72.6. HHS delegated authority for operating the Laboratory Registration and Select Agents Tracking Program to CDC.

After the terrorist events of September and October 2001, Congress passed the Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act Of 2001 (USA PATRIOT Act PDF version (PDF format). This was followed in June 2002, by passage of Public Health Security and Bioterrorism Preparedness and Response Act of 2002 PDF version (PDF format). The provisions of this Act were implemented by 42 CFR 73, Possession, Use and Transfer of Select Agents; Interim Final Rule. The IFR was published in the Federal Register PDF version (PDF format) on December 13, 2002. The IFR underwent a staged implementation, beginning February 7, 2003. Public comment was invited on the IFR between December 13, 2002 and February 11, 2003, for consideration in promulgating the Final Rule.

The IFR was amended in November 2003 to provide for provisional entity registrations to prevent disruption or termination of ongoing research and educational projects by entities and individuals needing access to select agents and toxins.

The U.S. Departments of Health and Human Services (HHS) and Agriculture (USDA) published final rules for the possession, use, and transfer of select agents and toxins (42 C.F.R. Part 73, 7 C.F.R. Part 331, and 9 C.F.R. Part 121) in the Federal Register on March 18, 2005. All provisions of these final rules superseded those contained in the interim final rules and became effective on April 18, 2005.


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Animal and Plant Health Inspection Service Agricultural Select Agent Program 4700 River Road Unit 2, Mailstop 22, Cubicle 1A07 Riverdale, MD 20737 FAX: 301-734-3652 E-mail: ASAP@aphis.usda.gov and Centers for Disease Control and Prevention Division of Select Agents and Toxins 1600 Clifton Road NE, Mailstop A-46 Atlanta, GA 30333 FAX: 404-718-2096 E-mail: lrsat@cdc.gov