Containment Facility Design and Construction (Secondary Barriers) In high containment environments, such as BSL-3 and ABSL-3 laboratories, engineering controls play a significant role in preventing the release of pathogenic agents. Correct laboratory ventilation is one of the most effective engineering controls in high containment laboratories. The 5th edition of the CDC/NIH publication Biosafety in Microbiological and Biomedical Laboratories (BMBL) makes the following recommendations regarding the design of BSL-3 and ABSL-3 laboratory ventilation systems:
The BMBL also makes the following recommendations regarding BSL-3/ABSL-3 general facility verification, as follows:
The Federal Select Agent Program is in agreement with these recommendations and has developed policy to apply these recommendations to our regulatory processes. These policies on HVAC verification and overall facility verification are described in the link: BSL-3/ABSL-3 Verification.(PDF 206KB) |
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