Congratulations to Shinya Yamanaka on winning the 2012 Nobel Prize in Physiology or Medicine for the discovery that mature cells can be reprogrammed to become pluripotent. Get to know his research by reading his outstanding State of the Art contribution to Clinical Pharmacology & Therapeutics on the use of induced pluripotent stem cells in drug development.
Volume 93, No 1
January 2013
ISSN: 0009-9236
EISSN: 1532-6535
Impact Factor 6.043*
Rank: 13/261 Pharmacology and Pharmacy
Editor-in-Chief:
Scott Waldman, MD, PhD, FCP
*2011 Journal Citation Report (Thomson Reuters, 2012)
FEATURED ARTICLES
IN THIS ISSUE
In This Issue FREECOMMENTARY
Integrating population science with individual genomic measurements FREETRANSLATION
Changing the culture of drug development FREESTATE OF THE ART
The potential for microRNAs in cancer therapy FREESTATE OF THE ART
Targeting senescent cells in aging and age-related diseases FREENews and Views
Research by Larry Hawk and colleagues suggests that a longer duration of varenicline treatment prior to smoking cessation improves abstinence outcomes. Read the article here. Read press coverage here.
Suicidal thoughts and behavior in clinical trials: a statistical assessment. Read the press release here!
TOP TEN MOST VIEWED PAPERS
The top ten charts the articles that have been downloaded most often over the previous 30 days, in HTML and PDF format, from the Clinical Pharmacology & Therapeutics website recently. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.
December 2012
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Research and Reviews
Latest research highlights and reviews from the NPG family of journals
- NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice Source: Nature
- 1,25-Dihydroxyvitamin D Exerts Similar Immunosuppressive Effects as UVR but Is Dispensable for Local UVR-Induced Immunosuppression - this content is FREE Source: Journal of Investigative Dermatology
- Systematic genetic interaction screens uncover cell polarity regulators and functional redundancy Source: Nature Cell Biology