Water-Soluble Vitamins & Related Biochemical
Compounds
Serum folate
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Table 1.1.a. Serum folate: Total population
Geometric mean and selected percentiles of serum concentrations (in ng/mL) for the total U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002. |
|
Geometric mean
(95% conf. interval) |
Selected percentiles (95% conf. interval) |
Sample
size |
|
5th |
50th |
95th |
Males and Females |
Total, 3 years and older |
13.5 |
(13.1-13.8) |
5.70 |
(5.50-6.00) |
13.6 |
(13.2-13.9) |
30.8 |
(29.9-32.0) |
15912 |
3–5 years |
18.5 |
(17.7-19.3) |
9.90 |
(8.80-10.8) |
18.3 |
(17.7-18.8) |
34.8 |
(32.0-41.0) |
799 |
6–11 years |
18.1 |
(17.6-18.7) |
9.90 |
(9.40-10.6) |
18.0 |
(17.6-18.5) |
33.2 |
(31.6-35.0) |
1908 |
12–19 years |
12.6 |
(12.2-13.1) |
6.00 |
(5.60-6.30) |
12.8 |
(12.4-13.4) |
24.7 |
(23.0-26.6) |
4332 |
20–39 years |
11.4 |
(11.0-11.9) |
5.10 |
(4.80-5.40) |
11.2 |
(10.8-11.8) |
25.1 |
(23.4-26.9) |
3184 |
40–59 years |
12.8 |
(12.3-13.2) |
5.50 |
(5.20-5.90) |
12.9 |
(12.4-13.3) |
28.7 |
(27.1-30.1) |
2674 |
60 years and older |
16.8 |
(16.3-17.3) |
6.80 |
(6.40-7.20) |
17.0 |
(16.4-17.6) |
40.3 |
(37.4-43.0) |
3015 |
Males |
Total, 3 years and older |
12.8 |
(12.4-13.2) |
5.50 |
(5.20-5.90) |
13.0 |
(12.5-13.4) |
28.3 |
(27.4-29.4) |
7747 |
3–5 years |
18.2 |
(17.1-19.4) |
9.40 |
(8.60-10.7) |
17.7 |
(16.4-18.6) |
41.0 |
(31.2-44.8) |
417 |
6–11 years |
17.8 |
(17.0-18.6) |
9.70 |
(8.90-10.7) |
17.7 |
(16.8-18.4) |
32.3 |
(29.6-35.9) |
973 |
12–19 years |
12.5 |
(12.0-13.0) |
6.00 |
(5.50-6.30) |
12.9 |
(12.3-13.3) |
24.6 |
(22.8-26.6) |
2169 |
20–39 years |
10.7 |
(10.3-11.2) |
5.00 |
(4.40-5.60) |
10.8 |
(10.2-11.3) |
21.9 |
(19.8-23.2) |
1355 |
40–59 years |
12.3 |
(11.9-12.7) |
5.40 |
(4.70-5.90) |
12.4 |
(12.1-12.9) |
26.7 |
(25.1-28.1) |
1337 |
60 years and older |
15.2 |
(14.7-15.8) |
6.10 |
(5.70-6.70) |
15.3 |
(14.7-16.1) |
35.4 |
(34.1-37.6) |
1496 |
Females |
Total, 3 years and older |
14.1 |
(13.7-14.5) |
5.80 |
(5.60-6.20) |
14.3 |
(13.8-14.7) |
32.9 |
(31.2-34.5) |
8165 |
3–5 years |
18.8 |
(18.0-19.7) |
10.3 |
(8.30-11.6) |
18.7 |
(17.5-19.1) |
33.5 |
(31.0-36.6) |
382 |
6–11 years |
18.5 |
(18.0-19.1) |
10.0 |
(9.30-10.7) |
18.6 |
(17.8-19.0) |
33.4 |
(30.0-37.4) |
935 |
12–19 years |
12.7 |
(12.2-13.3) |
6.20 |
(5.70-6.60) |
12.8 |
(12.3-13.5) |
24.8 |
(22.2-28.1) |
2163 |
20–39 years |
12.1 |
(11.6-12.6) |
5.40 |
(5.10-5.60) |
12.0 |
(11.4-12.8) |
28.7 |
(26.2-30.8) |
1829 |
40–59 years |
13.2 |
(12.7-13.8) |
5.50 |
(5.10-6.20) |
13.4 |
(12.7-14.0) |
30.2 |
(27.5-34.1) |
1337 |
60 years and older |
18.1 |
(17.3-18.8) |
7.40 |
(6.80-7.80) |
18.2 |
(17.3-18.9) |
43.0 |
(39.8-45.6) |
1519 |
Table 1.1.b. Serum folate: Mexican Americans
Geometric mean and selected percentiles of serum concentrations (in ng/mL) for Mexican Americans in the U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002. |
|
Geometric mean
(95% conf. interval) |
Selected percentiles (95% conf. interval) |
Sample
size |
|
5th |
50th |
95th |
Males and Females |
Total, 3 years and older |
12.4 |
(11.9-12.9) |
5.70 |
(5.30-6.20) |
12.5 |
(12.0-12.9) |
26.3 |
(24.8-28.1) |
4695 |
3–5 years |
18.1 |
(17.1-19.2) |
10.9 |
(9.90-11.5) |
17.7 |
(16.7-18.7) |
33.6 |
(28.6-36.8) |
266 |
6–11 years |
17.7 |
(17.1-18.4) |
10.4 |
(9.60-11.0) |
17.3 |
(16.7-17.9) |
31.0 |
(28.8-34.8) |
652 |
12–19 years |
12.4 |
(12.0-12.8) |
6.60 |
(6.10-6.90) |
12.6 |
(12.0-13.2) |
22.4 |
(21.7-24.0) |
1637 |
20–39 years |
10.5 |
(9.96-11.0) |
5.00 |
(4.20-5.60) |
10.3 |
(9.80-11.0) |
20.1 |
(19.4-21.9) |
866 |
40–59 years |
11.8 |
(11.1-12.5) |
5.90 |
(5.10-6.50) |
11.9 |
(11.2-12.4) |
23.8 |
(20.6-28.0) |
634 |
60 years and older |
14.4 |
(13.6-15.2) |
6.00 |
(5.00-6.90) |
14.8 |
(13.5-15.8) |
34.1 |
(30.2-38.7) |
640 |
Males |
Total, 3 years and older |
12.0 |
(11.4-12.5) |
5.50 |
(4.80-6.20) |
12.1 |
(11.4-12.6) |
25.3 |
(23.5-27.4) |
2293 |
3–5 years |
17.7 |
(16.6-18.9) |
10.5† |
(9.70-11.6) |
17.4 |
(16.1-18.5) |
34.0† |
(27.1-44.8) |
139 |
6–11 years |
17.6 |
(16.7-18.5) |
10.1 |
(9.00-11.0) |
17.5 |
(16.4-18.4) |
32.1 |
(26.2-42.0) |
338 |
12–19 years |
12.5 |
(12.0-13.1) |
6.40 |
(5.80-7.00) |
12.6 |
(12.0-13.3) |
24.1 |
(22.1-26.3) |
811 |
20–39 years |
9.85 |
(9.24-10.5) |
4.50 |
(3.80-5.60) |
9.80 |
(9.20-10.6) |
19.3 |
(17.2-20.0) |
383 |
40–59 years |
11.6 |
(10.8-12.5) |
5.80 |
(5.10-6.60) |
11.7 |
(10.7-12.6) |
22.0 |
(18.4-28.7) |
301 |
60 years and older |
13.5 |
(12.5-14.5) |
6.20 |
(5.00-7.10) |
13.2 |
(12.2-14.8) |
29.8 |
(24.0-48.3) |
321 |
Females |
Total, 3 years and older |
12.9 |
(12.4-13.4) |
5.90 |
(5.70-6.40) |
13.0 |
(12.6-13.7) |
27.2 |
(25.6-28.8) |
2402 |
3–5 years |
18.5 |
(17.1-20.0) |
11.0† |
(9.60-12.0) |
18.3 |
(16.9-19.0) |
31.6† |
(27.4-36.6) |
127 |
6–11 years |
17.9 |
(17.2-18.6) |
10.5 |
(9.60-11.7) |
17.3 |
(16.6-18.2) |
30.8 |
(28.8-32.1) |
314 |
12–19 years |
12.2 |
(11.8-12.7) |
6.60 |
(6.10-7.00) |
12.5 |
(11.8-13.3) |
21.6 |
(19.8-22.4) |
826 |
20–39 years |
11.2 |
(10.7-11.8) |
5.20 |
(4.90-5.90) |
11.0 |
(10.3-11.7) |
22.3 |
(20.0-27.6) |
483 |
40–59 years |
11.9 |
(11.1-12.8) |
5.90 |
(4.60-6.50) |
12.0 |
(11.1-12.5) |
25.4 |
(21.4-26.6) |
333 |
60 years and older |
15.2 |
(14.3-16.2) |
6.10 |
(5.00-7.20) |
15.8 |
(14.4-16.7) |
36.0 |
(31.5-39.6) |
319 |
† Estimate is subject to greater uncertainty due to small cell size. |
Table 1.1.c. Serum folate: Non-Hispanic blacks
Geometric mean and selected percentiles of serum concentrations (in ng/mL) for non-Hispanic blacks in the U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002. |
|
Geometric mean
(95% conf. interval) |
Selected percentiles (95% conf. interval) |
Sample
size |
|
5th |
50th |
95th |
Males and Females |
Total, 3 years and older |
11.3 |
(10.9-11.8) |
5.10 |
(4.60-5.30) |
11.1 |
(10.6-11.6) |
25.5 |
(23.9-27.1) |
3716 |
3–5 years |
16.9 |
(16.0-17.8) |
9.80 |
(8.70-10.5) |
16.2 |
(15.1-17.8) |
34.8 |
(28.2-39.3) |
235 |
6–11 years |
16.9 |
(16.2-17.6) |
9.60 |
(8.80-10.6) |
16.4 |
(15.8-17.4) |
31.8 |
(28.0-39.5) |
604 |
12–19 years |
10.9 |
(10.5-11.4) |
5.30 |
(5.00-5.70) |
11.0 |
(10.5-11.4) |
19.8 |
(19.0-21.0) |
1256 |
20–39 years |
9.73 |
(9.18-10.3) |
5.10 |
(4.50-5.40) |
9.60 |
(9.10-10.4) |
19.8 |
(18.7-21.4) |
593 |
40–59 years |
10.3 |
(9.86-10.8) |
4.40 |
(4.10-5.10) |
10.1 |
(9.60-10.8) |
22.7 |
(19.4-26.0) |
541 |
60 years and older |
12.7 |
(11.6-13.8) |
4.80 |
(4.20-5.40) |
12.2 |
(11.0-14.0) |
38.1 |
(31.1-43.3) |
487 |
Males |
Total, 3 years and older |
10.9 |
(10.5-11.3) |
4.80 |
(4.40-5.10) |
10.8 |
(10.5-11.3) |
22.7 |
(21.2-25.0) |
1822 |
3–5 years |
16.6 |
(15.3-17.9) |
9.00† |
(7.50-10.6) |
15.6 |
(14.4-17.2) |
36.5† |
(26.1-55.9) |
122 |
6–11 years |
17.0 |
(16.3-17.8) |
9.60 |
(8.80-10.8) |
16.6 |
(15.9-17.6) |
31.6 |
(26.8-39.5) |
305 |
12–19 years |
11.0 |
(10.5-11.5) |
5.10 |
(4.60-5.80) |
11.2 |
(10.5-11.7) |
20.1 |
(19.2-22.2) |
640 |
20–39 years |
9.17 |
(8.63-9.74) |
4.50 |
(3.50-5.10) |
9.50 |
(8.40-10.2) |
17.4 |
(16.3-19.5) |
249 |
40–59 years |
9.69 |
(9.20-10.2) |
4.20 |
(3.00-4.70) |
9.80 |
(9.20-10.2) |
19.2 |
(17.8-20.6) |
274 |
60 years and older |
11.3 |
(10.3-12.4) |
4.60 |
(3.90-5.20) |
11.3 |
(9.90-12.6) |
33.8 |
(20.0-40.4) |
232 |
Females |
Total, 3 years and older |
11.7 |
(11.1-12.3) |
5.40 |
(4.80-5.70) |
11.2 |
(10.7-11.9) |
27.4 |
(25.1-30.4) |
1894 |
3–5 years |
17.2 |
(15.8-18.8) |
10.2† |
(7.80-10.9) |
17.2 |
(15.2-18.8) |
30.9† |
(27.1-36.3) |
113 |
6–11 years |
16.7 |
(16.0-17.5) |
9.60 |
(7.90-10.5) |
16.3 |
(15.5-17.3) |
32.5 |
(27.1-38.4) |
299 |
12–19 years |
10.8 |
(10.3-11.4) |
5.40 |
(5.00-5.80) |
10.8 |
(10.3-11.3) |
19.4 |
(18.3-21.0) |
616 |
20–39 years |
10.2 |
(9.49-10.9) |
5.40 |
(4.50-5.70) |
9.70 |
(9.20-10.7) |
21.4 |
(19.2-24.0) |
344 |
40–59 years |
10.9 |
(10.2-11.7) |
4.70 |
(3.50-5.90) |
10.6 |
(9.50-12.1) |
24.8 |
(19.6-29.2) |
267 |
60 years and older |
13.6 |
(12.2-15.2) |
5.10 |
(3.80-6.60) |
12.7 |
(11.6-14.9) |
39.5 |
(30.5-48.0) |
255 |
† Estimate is subject to greater uncertainty due to small cell size. |
Table 1.1.d. Serum folate: Non-Hispanic whites
Geometric mean and selected percentiles of serum concentrations (in ng/mL) for non-Hispanic whites in the U.S. population aged 3 years and older, National Health and Nutrition Examination Survey, 1999–2002. |
|
Geometric mean
(95% conf. interval) |
Selected percentiles (95% conf. interval) |
Sample
size |
|
5th |
50th |
95th |
Males and Females |
Total, 3 years and older |
14.1 |
(13.6-14.6) |
6.00 |
(5.70-6.30) |
14.2 |
(13.7-14.8) |
32.0 |
(30.9-33.3) |
6147 |
3–5 years |
19.6 |
(18.3-21.1) |
10.1† |
(8.30-12.3) |
18.9 |
(17.8-20.2) |
38.0† |
(31.5-48.9) |
219 |
6–11 years |
18.7 |
(17.9-19.5) |
9.70 |
(8.90-10.8) |
18.8 |
(17.9-19.5) |
34.2 |
(31.6-37.8) |
494 |
12–19 years |
13.3 |
(12.8-13.9) |
6.20 |
(5.70-6.70) |
13.6 |
(13.1-14.3) |
26.5 |
(24.0-27.6) |
1073 |
20–39 years |
11.9 |
(11.4-12.6) |
5.50 |
(4.80-5.90) |
12.2 |
(11.2-12.9) |
26.3 |
(24.0-29.1) |
1381 |
40–59 years |
13.3 |
(12.7-13.8) |
5.60 |
(5.20-6.10) |
13.3 |
(12.9-14.0) |
29.8 |
(27.4-31.0) |
1276 |
60 years and older |
17.4 |
(16.8-18.0) |
7.20 |
(6.60-7.60) |
17.8 |
(16.9-18.4) |
41.0 |
(37.4-43.5) |
1704 |
Males |
Total, 3 years and older |
13.3 |
(12.9-13.9) |
6.00 |
(5.60-6.30) |
13.6 |
(13.0-14.1) |
29.4 |
(28.1-30.6) |
3013 |
3–5 years |
19.2 |
(17.2-21.4) |
9.00† |
(7.80-11.1) |
18.7 |
(16.3-19.9) |
42.0† |
(29.9-57.6) |
116 |
6–11 years |
18.2 |
(17.0-19.5) |
8.90 |
(7.60-11.0) |
18.0 |
(16.8-19.2) |
34.7 |
(29.7-38.0) |
260 |
12–19 years |
13.0 |
(12.4-13.7) |
6.20 |
(5.60-6.80) |
13.4 |
(12.8-13.9) |
26.0 |
(22.8-27.3) |
536 |
20–39 years |
11.3 |
(10.6-12.0) |
5.40 |
(4.40-6.10) |
11.3 |
(10.4-12.4) |
23.0 |
(20.2-24.5) |
577 |
40–59 years |
12.7 |
(12.2-13.3) |
5.70 |
(5.20-6.40) |
13.0 |
(12.3-13.5) |
27.3 |
(25.4-28.8) |
666 |
60 years and older |
15.8 |
(15.1-16.5) |
6.30 |
(6.10-7.30) |
16.0 |
(15.2-17.0) |
35.9 |
(33.6-37.6) |
858 |
Females |
Total, 3 years and older |
14.9 |
(14.3-15.4) |
6.10 |
(5.80-6.50) |
15.1 |
(14.5-15.7) |
34.2 |
(32.4-35.8) |
3134 |
3–5 years |
20.1 |
(18.8-21.5) |
11.6† |
(8.30-14.1) |
19.1 |
(18.4-21.6) |
33.5† |
(28.9-39.0) |
103 |
6–11 years |
19.2 |
(18.3-20.1) |
10.2 |
(8.90-11.1) |
19.4 |
(18.8-20.2) |
33.6 |
(29.4-40.3) |
234 |
12–19 years |
13.7 |
(12.9-14.5) |
6.40 |
(5.20-7.10) |
13.9 |
(13.2-14.7) |
26.6 |
(23.0-31.6) |
537 |
20–39 years |
12.6 |
(12.0-13.4) |
5.60 |
(5.10-5.90) |
13.0 |
(11.8-13.7) |
30.4 |
(26.3-32.4) |
804 |
40–59 years |
13.8 |
(13.1-14.6) |
5.70 |
(5.10-6.30) |
13.9 |
(12.9-15.1) |
31.0 |
(28.7-35.0) |
610 |
60 years and older |
18.8 |
(18.0-19.7) |
7.70 |
(7.20-8.60) |
18.9 |
(18.0-19.8) |
43.6 |
(40.0-46.1) |
846 |
† Estimate is subject to greater uncertainty due to small cell size. |