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National HIV/AIDS Program | | | |
| Epzicom
(Epivir + Ziagen)
- Type of Drug: Fixed-Dose Combination
Fixed-dose combinations combine the most commonly prescribed doses of several medications into 1 pill. This pill is a combination of drugs known as nucleoside reverse transcriptase inhibitors, also called NRTIs, nucleoside analogues, or "nukes." These were the first type of drug available to treat HIV.
When the HIV virus enters a healthy cell, it attempts to make copies of itself. It does this by using an enzyme called reverse transcriptase. NRTIs block that enzyme, so HIV cannot make new copies of itself.
Notes on taking this medication- No food restrictions, can take with or without food
- Do not take Epzicom with Emtriva
- Persons with kidney problems may need an adjustment to their doses of
the component drugs, and have to take them separately, not as a single pill
Same side effects asEpivir- Side effects are rare but include headaches and general sense of feeling ill
- Epivir is active against hepatitis B, and stopping it can cause "flare-up" of hepatitis B
Ziagen- Mild nausea; vomiting; diarrhea; loss of appetite
- Rash
Caution! Ziagen can cause a serious allergic reaction that includes at least 2 of the following: fever, malaise, severe nausea, diarrhea, abdominal pain, sore throat, cough, shortness of breath, and rash. Symptoms usually begin within 6 weeks of starting medication. If you think you are having an allergic reaction, call your doctor at once. If allergic, you will have to stop Ziagen and never take it again. Starting it again can cause serious illness or death. See accompanying chart: Tips for Common Side Effects My doctor's instructionsDisclaimer:This information is not meant to substitute for advice from your medical provider or pharmacist. If you have any questions about your medication dosing, talk to your medical provider or pharmacist. | | | |
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Reviewed/Updated Date: September 28, 2008 |
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