UNTHSC Department of Laboratory Animal Medicine, Partners in Saving Lives  
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Pharmacy - Controlled Drugs

The following drugs are controlled:

  • Buprenorphine (BUPRENEX®)
  • Butorphanol (STADOL®)
  • Diazepam (VALIUM®)
  • Euthanasia solutions
  • Ketamine
  • Morphine
  • Pentobarbital
  • Sufentanil
  • Telazol

Controlled substances must be kept in a locked cabinet and forms indicating their use must be appropriately completed and filed. 

USDA Policy #3 states:

Expired Medical Materials

The use of expired medical materials such as drugs, fluids, or sutures on regulated animals is not considered to be acceptable veterinary practice and does not constitute adequate veterinary care as required by the regulations promulgated under the Animal Welfare Act. All expired medical materials found in a licensed or registered facility are to be brought to the attention of the responsible official. The facility must either dispose of all such materials or segregate them in an appropriately labeled, physically separate location from non-expired medical materials. The Animal & Plant Health Inspection Service (APHIS) has no jurisdiction over facilities using expired medical materials for non-regulated animals or non-regulated activities. For acute terminal procedures, APHIS does not oppose the use of expired medical materials if their use does not adversely affect the animal's well-being or compromise the validity of the scientific study.
Proper anesthesia, analgesia, and euthanasia are required for all such procedures. Drugs administered to relieve pain or distress and emergency drugs must not be used beyond their expiration date. Facilities allowing the use of expired medical materials in acute terminal procedures should have a policy covering the use of such materials and/or require investigators to describe in their animal activity proposals the intended use of expired materials. The attending veterinarian and the Institutional Animal Care and Use Committee (IACUC) are responsible for ensuring that proposed animal activities avoid or minimize discomfort, distress, and pain to the animal. These responsibilities cannot be met unless the veterinarian and the IACUC maintain control over the use of expired medical materials.

What does this mean?


All drugs and medical materials (saline bags, suture material, antibiotics, etc.) must be disposed of after the expiration date.

Example: Items stamped “12/09” may be used through December 31, 2009. It is outdated January 1, 2010. Dispose of the outdated items appropriately.

With the exception of emergency, anesthetic, analgesic, or euthanasia drugs; expired medical materials may be used on terminal surgeries provided: 

Materials are marked as “Expired—Use ONLY in TERMINAL Surgeries.
Materials are stored in a different location (cabinet, drawer, etc.) than materials used for survival surgeries.