09/09/2014
research article
New research by Jia-Min Zhang, Li-Lin Du and colleagues shows that a single protein, Pxd1, orchestrates the delicate balance between two structure-specific nucleases needed for the correct repair of DNA double-strand breaks.
Current Issue August 2014
09/09/2014
research article
Catherine Del Vecchio, Piyush Gupta and colleagues find that the regression of cancer cells to a de-differentiated state is linked to the gain of multi-drug resistance via the up-regulation of PERK-Nrf2 signaling, a potential new therapeutic target.
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09/09/2014
research article
Tun Li, Yousheng Shu and colleagues discover that different populations of inhibitory interneurons in the cerebral cortex express distinct subtypes of sodium channel, resulting in a diversity of electrical properties.
09/02/2014
research article and primer
MaryAnn Noonan, Matthew Rushworth and colleagues use fMRI studies of rhesus macaques to tease apart the neural correlates of social status. Read the accompanying Primer.
Image credit: Flickr user Martin Ng
09/02/2014
Research article and synopsis
Philippe Remigi, Catherine Masson-Boivin and colleagues show that stress-responsive error-prone DNA polymerase genes ease the evolution of a soil bacterium into a legume endosymbiont by accelerating adaptation of the bacterial genome to its new plant host. Read the accompanying Synopsis.
Image credit: DOI: 10.1371/journal.pbio.1000280
09/02/2014
Essay
In this Essay, Bill Sugden examines the evidence that links this ubiquitous human pathogen to cancer and multiple sclerosis.
Image credit: Albert Einstein College of Medicine
08/26/2014
research article and synopsis
Image credit: Mina Gouti
08/26/2014
Essay
Image credit: Pieter Bruegel the Elder
08/26/2014
research article
Image credit: Flickr user Mary Margret
Image credit: Rachelle Lauro
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