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Sponsors and Collaborators: |
Eastern Cooperative Oncology Group National Cancer Institute (NCI) |
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Information provided by: | National Cancer Institute (NCI) |
ClinicalTrials.gov Identifier: | NCT00898963 |
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment.
PURPOSE: This laboratory study is looking at biomarkers in patients with stage III or stage IV follicular lymphoma treated on clinical trial E-1496.
Condition | Intervention |
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Lymphoma |
Genetic: gene expression analysis Genetic: microarray analysis Genetic: polymorphism analysis Other: immunohistochemistry staining method Other: immunologic technique Other: laboratory biomarker analysis |
Study Type: | Observational |
Official Title: | Identification of Biomarkers in Follicular Lymphoma |
Estimated Enrollment: | 175 |
Study Start Date: | April 2007 |
OBJECTIVES:
OUTLINE: This is a multicenter study.
Tissue samples are analyzed by gene expression profiling, microarrays to predict gene expression, immunohistochemistry, and immunoglobulin Fc-gamma receptor polymorphism analysis for biological markers.
PROJECTED ACCRUAL: A total of 175 samples will be accrued for this study.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
Diagnosis of follicular lymphoma
PATIENT CHARACTERISTICS:
PRIOR CONCURRENT THERAPY:
Study ID Numbers: | CDR0000544400, ECOG-E1496T1 |
Study First Received: | May 9, 2009 |
Last Updated: | May 16, 2009 |
ClinicalTrials.gov Identifier: | NCT00898963 History of Changes |
Health Authority: | United States: Federal Government |
stage III grade 1 follicular lymphoma stage III grade 2 follicular lymphoma stage III grade 3 follicular lymphoma |
stage IV grade 1 follicular lymphoma stage IV grade 2 follicular lymphoma stage IV grade 3 follicular lymphoma |
Lymphatic Diseases Immunoproliferative Disorders Lymphoma, Follicular Lymphoma, Non-Hodgkin |
Lymphoproliferative Disorders Follicular Lymphoma Lymphoma |
Lymphatic Diseases Neoplasms Immunoproliferative Disorders Neoplasms by Histologic Type Immune System Diseases |
Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoproliferative Disorders Lymphoma |