Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsors and Collaborators: |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
---|---|
Information provided by: | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
ClinicalTrials.gov Identifier: | NCT00147342 |
Most children with type 1 diabetes have a drop in the blood sugar during exercise. This drop in the blood sugar can result in hypoglycemia (low blood sugar). In children using an insulin pump, there is an opportunity to reduce the basal insulin rate during exercise. This study is being conducted to determine if decreasing the insulin that is received during exercise will reduce the risk of hypoglycemia. We hope to learn more about how the body responds to hypoglycemia and to hyperglycemia (high blood sugar) when it occurs.
As part of the study, children will have a visit on two different days. During each visit, children will exercise on a treadmill for about 60 minutes. During one of the visits, the children's basal rate will be continued during the exercise. During one visit, the basal insulin will be stopped. The blood sugar will be checked frequently during the exercise.
Condition |
---|
Diabetes Mellitus, Type I |
Study Type: | Observational |
Study Design: | Prospective |
Official Title: | The Effect of Basal Insulin During Exercise on the Development of Hypoglycemia in Children With Type 1 Diabetes |
Estimated Enrollment: | 55 |
Study Start Date: | May 2005 |
Estimated Study Completion Date: | December 2005 |
Ages Eligible for Study: | 8 Years to 17 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
United States, California | |
Division of Pediatric Endocrinology and Diabetes, Stanford University | |
Stanford, California, United States, 94305-5208 | |
United States, Colorado | |
Barbara Davis Center for Childhood Diabetes, University of Colorado | |
Aurora, Colorado, United States, 80010 | |
United States, Connecticut | |
Department of Pediatrics, Yale University School of Medicine | |
New Haven, Connecticut, United States, 06519 | |
United States, Florida | |
Jaeb Center for Health Research | |
Tampa, Florida, United States, 33647 | |
Nemours Children's Clinic | |
Jacksonville, Florida, United States, 32207 | |
United States, Iowa | |
Department of Pediatrics, University of Iowa Carver College of Medicine | |
Iowa City, Iowa, United States, 52242 |
Study Chair: | William V Tamborlane, M.D. | Department of Pediatrics, Yale University School of Medicine |
Study ID Numbers: | DirecNet 007, HD041890, HD041906, HD041918, HD041915, HD041908, HD041919 |
Study First Received: | September 2, 2005 |
Last Updated: | January 10, 2008 |
ClinicalTrials.gov Identifier: | NCT00147342 History of Changes |
Health Authority: | United States: Federal Government |
exercise hypoglycemia Diabetes Mellitus, Type I glucose monitoring |
Autoimmune Diseases Metabolic Diseases Diabetes Mellitus, Type 1 Diabetes Mellitus Endocrine System Diseases Diabetes Mellitus Type 1 |
Endocrinopathy Glucose Metabolism Disorders Hypoglycemia Metabolic Disorder Insulin |
Autoimmune Diseases Metabolic Diseases Immune System Diseases Diabetes Mellitus, Type 1 |
Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders |