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Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news on the impact of the environment on human health. EHP is published by the National Institute of Environmental Health Sciences and its content is free online. Print issues are available by paid subscription.DISCLAIMER
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Environmental Health Perspectives Volume 88, 1990
Environmental Health Perspectives  1990 Risk Factors and Mechanisms in Carcinogenesis

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Prostaglandin synthase-mediated metabolism of carcinogens and a potential role for peroxyl radicals as reactive intermediates
Marnett-LJ
p. 5
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Cellular responses to oxidative stress: the [Ah] gene battery as a paradigm
Nebert-DW; Petersen-DD; Fornace AJ Jr
p. 13
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A novel pathway to the ultimate mutagens of aromatic amino and nitro compounds
Wild-D
p. 27
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Crystallization of prostaglandin-H synthase for X-ray structure analysis
Jahnke-K; Degen-GH; Buehner-M
p. 33
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Stereoselective metabolism of dibenz(a,h)anthracene to trans-dihydrodiols and their activation to bacterial mutagens
Platt-KL; Schollmeier-M; Frank-H; Oesch-F
p. 37
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Sulfotransferase-mediated chlorination of 1-hydroxymethylpyrene to a mutagen capable of penetrating indicator cells
Glatt-H; Henschler-R; Phillips-DH; Blake-JW; Steinberg-P; Seidel A; Oesch-F
p. 43
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Rat and human liver cytosolic epoxide hydrolases: evidence for multiple forms at level of protein and mRNA
Thomas-H; Schladt-L; Doehmer-J; Knehr-M; Oesch-F
p. 49
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Mass spectrometric peptide mapping analysis and structural characterization of dihydrodiol dehydrogenase isoenzymes
Gauss-C; Klein-J; Post-K; Suckau-D; Schneider-K; Thomas-H; Oesch-F; Przybylski-M
p. 57
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Genetically engineered V79 Chinese hamster cells metabolically activate the cytostatic drugs cyclophosphamide and ifosfamide
Doehmer-J; Seidel A; Oesch-F; Glatt-HR
p. 63
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Studies of the expression of the cytochrome P450IA, P450IIB, and P450IIC gene family in extrahepatic and hepatic tissues
Friedberg-T; Siegert-P; Grassow-MA; Bartlomowicz-B; Oesch-F
p. 67
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Rat liver endothelial and Kupffer cell-mediated mutagenicity of polycyclic aromatic hydrocarbons and aflatoxin B1
Steinberg-P; Schlemper-B; Molitor-E; Platt-KL; Seidel A; Oesch-F
p. 71
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Genetic modulation of the cellular antioxidant defense capacity
Amstad-P; Cerutti-P
p. 77
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Activity of carcinogens that bind to the C8 position of guanine residues in an assay specific for the detection of -2 frameshift mutations in a defined hot spot
Fuchs-RP; Bintz-R
p. 83
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Photobiological studies with dioxetanes in isolated DNA, bacteria, and mammalian cells
Adam-W; Beinhauer A; Mosandl-T; Saha-Moller-C; Vargas-F; Epe-B; Muller-E; Schiffmann-D; Wild-D
p. 89
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Molecular mechanisms of DNA damage initiated by alpha, beta-unsaturated carbonyl compounds as criteria for genotoxicity and mutagenicity
Eder-E; Hoffman-C; Bastian-H; Deininger-C; Scheckenbach-S
p. 99
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A mechanism of haloalkene-induced renal carcinogenesis
Dekant-W; Vamvakas-S; Koob-M; Kochling A; Kanhai-W; Muller-D; Henschler-D
p. 107
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Identification of ultimate DNA damaging oxygen species
Epe-B; Hegler-J; Wild-D
p. 111
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Role of metabolic activation in the carcinogenicity of estrogens: studies in an animal liver tumor model
Metzler-M; Blaich-G; Tritscher AM
p. 117
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Covalent binding of reactive estrogen metabolites to microtubular protein as a possible mechanism of aneuploidy induction and neoplastic cell transformation
Epe-B; Harttig-U; Stopper-H; Metzler-M
p. 123
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Quantification of thioguanine-resistant lymphocytes from mice irradiated in vivo
Lorenz-R; Gollner-T; Hempel-K
p. 129
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Products of the fos and jun proto-oncogenes bind cooperatively to the AP1 DNA recognition sequence
Risse-G; Neuberg-M; Hunter-JB; Verrier-B; Muller-R
p. 133
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Retroviruses as genetic tools to isolate transcriptionally active chromosomal regions
von-Melchner-H; Ruley-HE
p. 141
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Modulating factors in the expression of radiation-induced oncogenic transformation
Hall-EJ; Hei-TK
p. 149
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Genetic and molecular analysis of six tumor suppressor genes in Drosophila melanogaster
Loffler-T; Wismar-J; Sass-H; Miyamoto-T; Becker-G; Konrad-L; Blondeau-M; Protin-U; Kaiser-S; Graf-P; et-al
p. 157
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Molecular action of the l(2)gl tumor suppressor gene of Drosophila melanogaster
Merz-R; Schmidt-M; Torok-I; Protin-U; Schuler-G; Walther-HP; Krieg-F; Gross-M; Strand-D; Mechler-BM
p. 163
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Radiation-induced cell transformation: transformation efficiencies of different types of ionizing radiation and molecular changes in radiation transformants and tumor cell lines
Hieber-L; Trutschler-K; Smida-J; Wachsmann-M; Ponsel-G; Kellerer AM
p. 169
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Activation of cellular oncogenes by chemical carcinogens in Syrian hamster embryo fibroblasts
Ebert-R; Barrett-JC; Wiseman-RW; Pechan-R; Reiss-E; Rollich-G; Schiffmann-D
p. 175
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Retinoic acid induced differentiation and commitment in HL-60 cells
Meyer-PA; Kleinschnitz-C
p. 179
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Alteration of topoisomerase II action is a possible molecular mechanism of HL-60 cell differentiation
Gieseler-F; Boege-F; Clark-M
p. 183
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Morphological, biochemical, and molecular biological characterization of a rat rhabdomyosarcoma cell line during differentiation induction in vitro
Gerharz-CD; Doehmer-J; Mayer-H; Oesch-F; Gabbert-H
p. 187
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The malignant conversion step of mouse skin carcinogenesis
Yuspa-SH; Hennings-H; Roop-D; Strickland-J; Greenhalgh-DA
p. 193
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Growth-related alterations during liver carcinogenesis: effect of promoters
Seglen-PO; Gerlyng-P
p. 197
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Role of genotoxic and nongenotoxic effects in multistage carcinogenicity of aromatic amines
Neumann-HG; Hammerl-R; Hillesheim-W; Wildschutte-M
p. 207
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Binding of aromatic amines to the rat hepatic Ah receptor in vitro and in vivo and to the 8S and 4S estrogen receptor of rat uterus and rat liver
Cikryt-P; Kaiser-T; Gottlicher-M
p. 213
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Role of prostaglandin-H synthase in mediating genotoxic and carcinogenic effects of estrogens
Degen-GH
p. 217
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Immune deficiency as a risk factor in Epstein-Barr virus-induced malignant diseases
Purtilo-DT; Okano-M; Grierson-HL
p. 225
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Observations and thoughts on oligosaccharide involvement in malignancy
Feizi-T
p. 231
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Characteristics of T-lymphocytes infiltrating human B-cell lymphomas
Marquardt-P; Muller-Hermelink-HK
p. 233
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Induction and progression of human lymphoproliferative lesions by Epstein-Barr virus
Chappuis-BB; Muller-Hermelink-HK
p. 237
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Development of HPLC methods for the purification and analysis of plasma membrane glycoproteins
Renauer-D; Gierlich-HU; Unger-KK
p. 243
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Synthetic tumor-associated glycopeptide antigens
Kunz-H; Wernig-P; Schilling-M; Marz-J; Unverzagt-C; Birnbach-S; Lang-U; Waldmann-H
p. 247
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Growth control in mammalian cells by cell-cell contacts
Wieser-RJ; Renauer-D; Schafer A; Heck-R; Engel-R; Schutz-S; Oesch-F
p. 251
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The role of the Thomsen-Friedenreich antigen as a tumor-associated molecule
Dippold-W; Steinborn A; Meyer-zum-Buschenfelde-KH
p. 255
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Workshop on fiber toxicology research needs
Dement-JM
p. 261
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Historical developments and perspectives in inorganic fiber toxicity in man
Selikoff-IJ
p. 269
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Human occupational and nonoccupational exposure to fibers
Esmen-NA; Erdal-S
p. 277
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Human epidemiology: a review of fiber type and characteristics in the development of malignant and nonmalignant disease
Merchant-JA
p. 287
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Human disease consequences of fiber exposures: a review of human lung pathology and fiber burden data
Roggli-VL
p. 295
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The relationship between fibrosis and cancer in experimental animals exposed to asbestos and other fibers
Davis-JM; Cowie-HA
p. 305
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Effects of fiber characteristics on lung deposition, retention, and disease
Lippmann-M
p. 311
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In vitro studies on the biologic effects of fibers: correlation with in vivo bioassays
Mossman-BT
p. 319
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Parental occupation and childhood cancer: review of epidemiologic studies
Savitz-DA; Chen-JH
p. 325
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