Toxicity is the degree to which a substance or a mixture of substances can harm humans or animals. The EPA conducts toxicity assessments to characterize the properties and effects of chemicals and compounds, with special emphasis on the establishment of dose-response characteristics. To facilitate these assessments, the EPA uses a scale of toxicity, from acute to subchronic, for measuring the harmfulness of each substance. The Agency also manages the Toxics Release Inventory, a database of toxic chemicals that are being used, manufactured, treated, transported, or released into the environment.

Recommended EPA Web pages

• National Center for Computational Toxicology (NCCT)
  Provides information about the National Center for Computational Toxicology.
• Toxics Release Inventory (TRI) Program
  This database contains information on toxic chemical releases and other waste management activities reported annually by certain covered industry groups as well as federal facilities.
• Integrated Risk Information System (IRIS)
  A database of human health effects that may result from exposure to various substances found in the environment.

Children's Health
School Environments

Exposure
Acute Exposure, Cumulative Exposure, Dermal Exposure, Dietary Exposure, Exposure Assessment, Exposure Route, Threshold Level

Food Safety
Irradiated Food

Health Assessment

Health Effects
Asthma, Genetic Damage, Respiratory Disease

Occupational Health
Worker Protection, Worker Safety

Seniors' Health
Aging Initiative

Sun Protection

Toxicity
Chronic Toxicity, Dermal Toxicity, Toxicological Profile