Pediatric Counter-Terrorism Measures

Anthrax

• Cipro (Ciprofloxacin Hydrochloride Approved for Inhalation Anthrax)
  • Cipro: Approved Dosing for Children [PDF] (label approved 5/18/2005)
  • CIPRO (Ciprofloxacin): Use by Pregnant and Lactating Women
  • Information for Consumers on Cipro: Questions and Answers
    
    
• Doxycycline and Penicillin G Procain for Inhalational Anthrax (Post-Exposure)
  • Public Health Emergency Home Preparation Instructions for Doxycycline  Includes the pamphlet, "In an Emergency: How to Prepare Doxycycline for Children and Adults Who Cannot Swallow Pills" (updated 7/2/2008)
  • Palatability Evaluations of Doxycycline Solid Dosage Tablets Ground and Mixed in Food or Drinks (Issued and posted 7/3/2002)
  • Stability and Dose Uniformity Evaluations of Doxycycline Solid Dosage Tablets Ground and Mixed in Food or Drinks  (Issued and posted 7/3/2002)
  • Doxycycline (Vibramycin, Monodox, Doryx, Doxy , Atridox, Periodox, Vibra-Tabs ): Use by Pregnant and Lactating Women
  • Information for Consumers on Doxycycline
  • Information for Consumers on Penicillin G Procaine
    
    
• Amoxicillin (Amoxil, Larotid, Trimox, Wymox) Use by Pregnant and Lactating Women  (Posted 11/20/2001)
  
  
• Commentary on Non-Labeled Dosing of Oral Amoxicillin in Adults and Pediatrics for Post-Exposure Inhalational Anthrax  (12/17/2001) 

  Chemical Agents

• Atropen (atropine autoinjector).  FDA has approved new dosage forms of the Atropen for use in children and adolescents exposed to certain nerve agents or insecticides. The Atropen has been approved since 1973 for use in adults.  FDA Talk Paper (Posted 6/20/2003)
  
  

   Radiation Emergencies

• The FDA announces conditions under which calcium-DTPA (Ca-DTPA) and zinc-DTPA (Zn-DTPA) can be found to be safe and effective for the treatment of internal contamination with plutonium, americium, or curium to increase the rates of elimination of these substances from the body.  Calcium-DTPA and Zinc-DTPA Information. (For pediatric information, please view the labels.) (Posted 9/12/2003) 
  
  
• Potassium Iodide as a Thyroid Blocking Agent in Radiation Emergencies [PDF] (Issued 12/2001, Posted 12/10/2001)
  FDA has released guidance on using potassium iodide to reduce the risk of thyroid cancer in children and adults in emergencies involving the release of radioactive iodine into the environment.
  • FDA Talk Paper: Guidance on Protection of Children and Adults Against Thyroid Cancer in Case of Nuclear Accident.  (Issued 12/10/2001)
  • Home Preparation Procedure for Emergency Administration of Potassium Iodide Tablets to Infants and Small Children.   Optional Format: PDF   (Issued and posted 7/3/2002)
    • Easy-to-use, one-page instructions for home preparation of 130 mg tablets: Optional Format: PDF   (Issued and posted 10/22/2002)
    • Easy-to-use, one-page instructions for home preparation of 65 mg tablets: Optional Format: PDF (Issued and posted 10/22/2002) 
  • Frequently Asked Questions on Potassium Iodide (KI).  (Posted 2/21/2002)   (Updated 3/18/2003)
• Prussian Blue.  FDA announces conditions under which Prussian blue can be found safe and effective for the treatment of internal contamination with radioactive cesium, radioactive thallium, or non-radioactive thallium. (1/31/2003)
  • Prussian Blue: Approved Dosing for Children (draft labeling)
  •  FDA approves a New Drug Application for Radiogardase, also known as Prussian blue, to treat people exposed to radiation contamination, due to harmful levels of cesium-137 or thallium. (Posted 10/2/2003) 
    • FDA News
    • Questions and Answers on Prussian Blue