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Databases and Tools

Key Human Health Databases and Tools
Key Ecological Databases and Tools
Additional Databases and Tools

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Key Human Health Databases and Tools

  1. EPA Integrated Risk Information System (IRIS)
    IRIS is a database of human health effects that may result from exposure to various substances found in the environment.

  2. ntegrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK)
    The Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) attempts to predict blood-lead concentrations (PbBs) for children exposed to lead in their environment. The model allows the user to input relevant absorption parameters (e.g., the fraction of lead absorbed from water) as well as intake and exposure rates.

  3. Guidance Manual for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (PDF) ( 28 pp, 292 kb,  About PDF) (February 1994) NTIS #PB93-963510, OSWER #9285.7-15-1.
    Table of Contents and Glossary (PDF) ( 28 pp, 292 kb,  About PDF)
    Chapter 1 (PDF) (29 pp, 230 kb,  About PDF)
    Chapter 2 (PDF) ( 50 pp, 1,257 kb,  About PDF)
    Chapter 3 (PDF) ( 13 pp, 334 kb,  About PDF)
    Chapter 4 (PDF) ( 67 pp, 578 kb,  About PDF)
    Chapter 5 (PDF) ( 32 pp, 249 kb,  About PDF)
    Chapter 6 (PDF) ( 11 pp, 94 kb,  About PDF)
    Appendix A (PDF) ( 16 pp, 252 kb,  About PDF)
    Appendix B (PDF) ( 5 pp, 38 kb,  About PDF)

  4. Recommendations of the Technical Review Workgroup for Lead for an Approach to Assessing Risks Associated with Adult Exposures to Lead in Soil (PDF) ( 763 KB, 62 pp.,  About PDF) [EPA-540-R-03-001, OSWER Dir #9285.7-54] (January 2003)
    This document describes a methodology for assessing risks associated with non-residential adult exposures to lead in soil. The methodology focuses on estimating fetal blood lead concentration in women exposed to lead-contaminated soils. This approach also provides tools that can be used for evaluating risks of elevated blood lead concentrations among exposed adults. Based on the TRW's analysis of the data collected in the completed NHANES III survey (Phases 1 and 2), updated ranges for the baseline adult PbB and GSDi adult parameters in the EPA ALM have been included in the spreadsheets. Although the use of these updated ranges in the EPA ALM would not appreciably change PRGs calculated with the methodology, it is recommended that data from both phases of NHANES III be used in all PbB analyses; this is consistent with CDC recommendations.

  5. Adult Lead Model spreadsheet (Calculation of PRGs, Appendix B of Adult Lead Model Guidance) (Lotus 1-2-3, 37 KB) [EPA-540-R-03-001, OSWER Dir #9285.7-54]
    Adult Lead Model spreadsheet (Excel, 97 KB) (Calculation of PRGs, Appendix B of Adult Lead Model Guidance) [EPA-540-R-03-001, OSWER Dir #9285.7-54]
    Adult Lead Model Review Report (PDF) (82 pp, 1.7 mb,  About PDF,) [EPA 9285.7-46]

  6. Risk Assessment Guidance for Superfund, Volume I
    Part D (1998)

  7. Soil Screening Calculations
    Soil Screening Guidance is a tool for screening at National Priorities List (NPL) sites.

  8. Soil Screening Calculations (for Radionuclides)
    Soil Screening Guidance is a tool for screening at National Priorities List (NPL) sites.

  9. Johnson and Ettinger (1991) Model for Subsurface Vapor Intrusion into Buildings
    A series of models for estimating indoor air concentrations and associated health risks from subsurface vapor intrusion into buildings. These models were based on the analytical solutions of Johnson and Ettinger (2001) for contaminant partitioning and subsurface vapor transport into buildings.

  10. Vapor Intrusion Guidance
    A draft guidance that provides current technical and policy recommendations on determining if the vapor intrusion pathway poses an unacceptable risk to human health at cleanup sites

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Key Ecological Databases and Tools

  1. Ecotox Thresholds (1996)
    EPA-developed software that calculates Ecotox Thresholds (ETs) for selected chemicals

  2. Wildlife Exposure Factors Handbook (1993)
    The Wildlife Exposure Factors Handbook provides data, references, and guidance for conducting exposure assessments for wildlife species exposed to toxic chemicals in their environment.

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Additional Databases and Tools

  1. Chemical Accident Risk Assessment ThesaurusSM (CARATSM)Link to EPA's External Link Disclaimer

  2. CARATSM provides a means to compare risk assessment approaches for chemical facilities located in various countries.

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