Distributed Structure-Searchable Toxicity (DSSTox) Database Network is a project of EPA's National Center for Computational Toxicology, helping to build a public data foundation for improved structure-activity and predictive toxicology capabilities. The DSSTox website provides a public forum for publishing downloadable, structure-searchable, standardized chemical structure files associated with toxicity data. More>
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DSSTox Structure-Browser information Page
27 March 2009![bar](Images/redfadebar_right.gif)
ARYEXP: European Bioinformatics Institute (EBI) ArrayExpress Repository for Gene Expression Experiments **Updated to v2a
Corresponds to updated content of EBI ArrayExpress website as of 20 January 2009.
GEOGSE: National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) Series Experiments **Updated to v2a
Corresponds to updated content of NCBI GEO website as of 02 February 2009.
NTPHTS: National Toxicology Program High-Throughput Screening Structure-Index File **Updated to v2c
Minor modifications to 9 structures based on additional review.
19 February 2009![bar](Images/redfadebar_right.gif)
KIERBL: EPA Estrogen Receptor Ki Binding Study (Laws et al.) Database File ** New File
Includes experimental Estrogen Receptor (ER) binding IC50 and Ki results for 50 chemicals (17 binders) included in the Main Citation (Laws et al., 2006) and previously unpublished results for 228 structurally diverse environmental chemicals for which no ER binding was observed in initial screening studies.
ARYEXP: European Bioinformatics Institute (EBI) ArrayExpress Repository for Gene Expression Experiments **Updated to v2a
Corresponds to updated content of EBI ArrayExpress website as of 20 January 2009.
GEOGSE: National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO) Series Experiments **Updated to v2a
Corresponds to updated content of NCBI GEO website as of 02 February 2009.
12 February 2009![bar](Images/redfadebar_right.gif)
TOXCST: Research Chemical Inventory for EPA's ToxCast Program ** Updated to v3a
Minor QC corrections and new fields for identifying replicates and parent0-metabolite pairs.
**Announcement: The DSSTox TOXCST Structure-Index File will accompany high-throughput screening and in vivo bioassay data being made available for this chemical inventory to participants of the first ToxCast™ Data Analysis Summit hosted by EPA's National Center for Computational Toxicology.
NTPBSI: National Toxicology Program Bioassay On-line Database Structure-Index Locator File ** Updated to v4b
Corresponds to updated content of NTP website as of 13 January 2009.
STRUCTURE_InChI and STRUCTURE_InChIKey field entries in newly published or updated files will conform to newly released InChI 1.02 Standards .
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