Definition of daunorubicin hydrochloride - National Cancer Institute Drug Dictionary

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daunorubicin hydrochloride
The hydrochloride salt of an anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Check for or using this agent. ()

Synonyms:		cloridrato de daunorubicina daunomycin hydrochloride daunomycin-HCL daunorubicin dauno-rubidomycine rubomycin C

US brand names:		Cerubidine Rubidomycin

Foreign brand names:		Cerubidin Daunoblastin Daunoblastina Ondena Rubilem

Abbreviations:		DNM DNR DRB

Code names:		FI-6339 RP-13057

Chemical structure names:		(8S-cis)-8-acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione 5,12-naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-, (8S-cis)-, hydrochloride 5,12-naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-(9CI) L-lyxo-hexopyranoside, 3.beta.-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-metldioxo-1a-naphthacenyl 3-amino-2,3,6-trideoxy-,.alpha.-,hydrochloride

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