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OER Grants News Archive - 2001
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News Archive Table Of Contents
Date |
News Flash Description |
December 19, 2001 |
NEW - Implementation Issues for Human Embryonic Stem Cell Research |
December 13, 2001 |
Reminder for Applicants Requesting Direct Costs of $500,000 or More |
December 7, 2001 |
NEW - Human Embryonic Stem Cell Research - Frequently Asked Questions and Relevant Information for Researchers |
November 27, 2001 |
Mail Addressed to the National Institutes of Health |
November 23, 2001 |
NEW - Human Embryonic Stem Cell Research - Frequently Asked Questions and Relevant Information for Researchers |
November 16, 2001 |
Human Embryonic Stem Cell Research - Frequently Asked Questions and Relevant Information for Researchers |
November 14, 2001 |
Revisions to Summary Statement Percentile Rankings |
November 7, 2001 |
The NIH Human Embryonic Stem Cell Registry is Now Available |
September 19, 2001 |
Delays in Grant Applications Submission and Other NIH Activities |
August 17, 2001 |
NIH Funding of Research Using Specified Existing Human Embryonic Stem Cells |
July 25, 2001 |
Proactive Compliance Site Visits FY 2001 Schedule |
July 10, 2001 |
Revised PHS 398 and PHS 2590 Now Available |
June 29, 2001 |
NIH On-Line Education Module on the Protection of Human Research Participants |
June 20, 2001 |
Follow-up Announcement on Delay of Applications Due to Tropical Storm Allison |
June 20, 2001 |
Tropical Storm Allison Disaster Relief |
June 20, 2001 |
Additional Information on Tropical Storm Allison |
June 12, 2001 |
Delays in Grant Application Submission due to Tropical Storm Allison |
April 23, 2001 |
NIH Clarifies Invention Reporting Guidance for Grantees Involved with the VA |
April 10, 2001 |
Workgroups Established to Address Regulatory Burdens |
April 4, 2001 |
NIH Announces Outcome of FY2000 Proactive Compliance Site Visits |
April 3, 2001 |
Notice on Required Invention Reporting |
March 26, 2001 |
NIH Statement in Response to the NAS Report |
March 22, 2001 |
Corrections and Clarifications to NIH Grants Policy Statement (Rev. 03/01) |
March 12, 2001 |
One Stop Shopping for NIH Information on Human Subjects and Financial Conflict of Interest |
February 28, 2001 |
Extension of Current PHS 398, 2590 and Related Forms |
February 27, 2001 |
Publication of the Revised NIH Grants Policy Statement |
January 12, 2001 |
FY 2001 Announcements on Salary Cap, NRSA Stipend Levels and Application Format |
News Flash Items
December 19, 2001: NEW - Implementation Issues for Human Embryonic Stem Cell Research
A new web page is available for grant applicants and research institutions interested in human embryonic stem cell research. This serves as a one-stop shopping portal for updated NIH Guide announcements, the Stem Cell Registry, archives of Frequently Asked Questions, and pertinent grants policy statements - http://grants.nih.gov/grants/stem_cells.htm. (Note added on 5/29/2003: See http://stemcells.nih.gov/index.asp for current NIH Stem Cell Information page.)
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December 13, 2001: Reminder for Applicants Requesting Direct Costs of $500,000 or More
On October 19, 2001, the NIH updated its policy on the acceptance of unsolicited applications requesting direct costs of $500,000 or more for any year of the grant. (See http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-004.html) Effective January 1, 2002, applicants must obtain agreement to accept assignment from Institute/Center staff at least 6 weeks prior to the submission date for any such application. Please note that the 6-week deadline for the February 1 receipt date is December 21.
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December 7, 2001: NEW - Human Embryonic Stem Cell Research - Frequently Asked Questions and Relevant Information for Researchers
The FAQ has been updated with additional information. Please see the following page: http://grants.nih.gov/grants/stem_cell_faqs.htm. (Note added on 5/29/2003: See http://stemcells.nih.gov/index.asp for current NIH Stem Cell Information page.)
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November 27, 2001: Mail Addressed to the National Institutes of Health
All applications and other deliveries to the Center for Scientific Review must either come via courier delivery or the USPS. Applications delivered by individuals to the Center for Scientific Review will no longer be accepted. For additional information, see the NIH Guide Notice (Nov. 13, 2001) http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-012.html.
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November 23, 2001: NEW - Human Embryonic Stem Cell Research - Frequently Asked Questions and Relevant Information for Researchers
The FAQ has been updated with additional information. Please see the following page: http://grants.nih.gov/grants/stem_cell_faqs.htm. (Note added on 5/29/2003: See http://stemcells.nih.gov/index.asp for current NIH Stem Cell Information page.)
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November 16, 2001: Human Embryonic Stem Cell Research - Frequently Asked Questions and Relevant Information for Researchers
In response to inquiries about the recent NIH guide notices pertaining to policies on human embryonic stem cell research, NIH will be posting periodically additional information to assist investigators and research administrators. This information will be provided in the form of frequently asked questions and the answers to these questions. The first installment of these are at URL http://grants.nih.gov/grants/stem_cell_faqs.htm. Monitor this site frequently for additional information. This was also announced in the NIH
Guide Notice of November 16, 2001. (Note added on 5/29/2003: See http://stemcells.nih.gov/index.asp for current NIH Stem Cell Information page.)
Additional information about the clearances required for the receipt of human embryonic stem cells developed outside of the U.S. is provided in the NIH Guide announcement Federal Government Clearances for Receipt of International Shipment of Human Embryonic Stem Cells at URL:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-013.html.
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November 14, 2001: Revisions to Summary Statement Percentile Rankings
Due to an error in the NIH information systems used to calculate percentiles, the percentiles shown on some summary statements mailed prior to November 13, 2001 may have been calculated incorrectly. Most rankings changed less than 1 percentile. Revised summary statements will be mailed the week of November 12 for affected applications. Issuance of other summary statements may be delayed a week. We apologize for any inconvenience caused to our applicant community.
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November 7, 2001: The NIH Human Embryonic Stem Cell Registry is Now Available
NIH has posted the NIH Human Embryonic Stem Cell Registry at
http://escr.nih.gov based on
the President's criteria in the NIH Guide for Grants and Contracts Notice
OD-02-005 along with related information in Notices
OD-02-006 and
OD-02-007.
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September 13, 2001: Delays in Grant Applications
Submission and Other NIH Activities
The tragic events of September 11 will
have many effects on operations at universities and research institutions, as
well as the NIH. The NIH realizes that this may cause problems for investigators
who are planning to submit grant applications. Applications that are submitted
late should include a cover letter noting the reasons for the delay. It is not
necessary to get permission in advance for such delays in grant application submission.
For most applicants a reasonable delay will be until normal communication and
delivery processes are functioning. For applicants in New York City, it is expected
that the delays may be considerably longer. Since there are still many uncertainties
at this time, it is difficult to give further guidance. As more information becomes
available, additional notices will be posted in the NIH Guide for Grants and Contracts.
Individuals who were scheduled to come to NIH for review or other meetings should check
with the Scientific Review Administrator or responsible Federal official about any changes.
This was also announced in the NIH
Guide Notice of September 19, 2001.
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August 17, 2001 (updated August 27, 2001): NIH Funding of Research Using Specified Existing Human Embryonic Stem Cells
In accordance with the President's announcement of August 9, 2001, (http://www.nih.gov/news/pr/aug2001/od-09.htm), the National Institutes of Health is initiating a process to enable researchers to use Federal funds to conduct research using human embryonic stem cells as long as the derivation process (which begins with the destruction of the embryo) was initiated prior to 9:00 p.m. EDT on August 9, and the following criteria are met: the stem cells must have been derived from an embryo that was created for reproductive purposes and was no longer needed; informed consent must have been obtained for donation of the embryo; and that donation must not have involved financial inducements. The President's complete remarks and related information are available at http://www.whitehouse.gov/news/releases/2001/08/20010809-2.html.
Investigators may not conduct research on any human embryonic stem cells until the NIH issues the policies and the procedures that will enable researchers and their institutions to document adherence to the criteria established by the President for use of these cells with Federal funds (direct and F&A). NIH has issued an update on existing human embryonic stem cells that can be found at http://stemcells.nih.gov/policy/statements/082701list.asp.
In order to facilitate research using human embryonic stem cells, the NIH is creating a Human Embryonic Stem Cell Registry that will list the human embryonic stem cells that meet the eligibility criteria. Specifically, the laboratories or companies that derived the cells listed on the Registry will have provided a signed assurance that the derivation process was initiated prior to 9:00 p.m. EDT on August 9, 2001; the stem cells were derived from an embryo that was created for reproductive purposes and was no longer needed; informed consent was obtained for donation of the embryo; and that donation did not involve financial inducements. The Registry will be accessible to investigators on the NIH Home Page http://www.nih.gov.
Initially, the Registry will contain basic information about the cells. This information will include a unique identifier; the name of the company or laboratory that derived the cells; contact information for the company/laboratory; and an assurance that the cells meet the President's criteria. In the future, to further assist researchers, additional information may also be included in the Registry, such as details about the derivation of the cells, the number of passages, culture conditions, and growth characteristics; a description of efforts to characterize the cells, including molecular markers and evidence of pluripotency; relevant publications; DNA fingerprinting data; and quality assurance data, such as the results of tests for Mycoplasma and standard human pathogens.
The NIH is working expeditiously to ensure that the Registry will be operational as soon as possible. General questions or comments about the Registry should be addressed to stemcellregistry@od.nih.gov. Researchers who are interested in studying or using particular human embryonic stem cells in their research will be expected to contact the company/laboratory directly to arrange for access to these cells. Investigators should be aware that, in some cases, existing cells need to be expanded in culture to reach larger numbers for the purposes of distribution, and that, in other cases, the derivations are still in the early stages of characterization and, thus, may not be immediately available.
With regard to the funding of research on both embryonic stem cells and adult stem cells in humans and animals, the NIH welcomes investigator-initiated grant applications proposing research using such stem cells, including requests to use existing funds or for supplements to existing grants to conduct such research. The NIH is also exploring a number of initiatives to facilitate research on all forms of stem cells. To hasten the development of a program of research and to stimulate submission of grant applications in this arena, some Institutes and Centers will be issuing Program Announcements to describe new, continuing, or expanded interests relevant to stem cell research, such as new approaches to the characterization of stem cells or the development of methods to differentiate cells into specific somatic cells for study. Other Institutes and Centers may issue specific Requests for Applications, which invite grant applications, include a special receipt date, and a set-aside of funds. Another possibility may be provision of resources (using contract or other mechanisms), in order to ensure adequate production of cells, means for their distribution, and adequate training of researchers as to how to maintain the cells. As usual, further updates and all solicitations will appear in the NIH Guide for Grants and Contracts that is available online at http://grants.nih.gov/grants/guide/index.html.
This was also announced in the NIH Guide Notice of August 27, 2001.
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July 25, 2001: Proactive Compliance Site Visits FY 2001 Schedule
The Division of Grants Compliance and Oversight in the Office of Policy for Extramural Research Administration (OPERA) has posted the FY2001 Proactive Compliance Site Visit Schedule on the Grants Compliance and Oversight Page. Institutions participating in the site visits were selected based on the level and nature of NIH support, geographic diversity, and type of institution; these institutions also are not engaged in an active compliance case with OPERA. The eight FY2001 site visit participants include five educational institutions, 2 AIRI (Association of Independent Research Institutes) member institutes, and 1 hospital. Please refer to "Proactive Compliance Site Visits 2000: A Compendium of Findings and Observations" for further information about the NIH Proactive Compliance Site Visits.
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July 10, 2001: Revised PHS 398 and PHS 2590 Now Available
The new PHS 398 application and PHS 2590 progress report instructions and forms are available on the NIH Grants Web site at http://grants.nih.gov/grants/forms.htm, and may now be used by applicants. Beginning January 10, 2002, use of the revised forms are required. The forms available on our website are now fillable using Adobe Acrobat Reader Software. Applicants are encouraged to access the instructions and forms via the Internet because they contain valuable links to policy documents as well as links for navigating the instructions easily. For further information, contact GrantsInfo@NIH.GOV. See NIH Guide Notice of July 10, 2001 for more details or contact heffernj@od.nih.gov.
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June 29, 2001: NIH On-Line Education Module on the Protection of Human Research Participants
This is a reminder that the NIH provides an online education module on the protection of human research participants that is specifically designed for extramural investigators. Completing this module fulfills the NIH education requirement in the protection of human research participants for key personnel (http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-039.html). This education module was initiated in January 2001 and can be accessed at the following URL: http://cme.cancer.gov/clinicaltrials/learning/humanparticipant-protections.asp. Before developing this module specifically for extramural scientists, the NIH made available an on-line course that was designed for our intramural investigators. At this time, however, we strongly encourage extramural investigators to use the extramural module if they choose to complete an NIH course.
Also see the September 5, 2001 NIH Guide Notice for additional information.
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June 20, 2001: Follow-up Announcement on Delay of Applications Due to Tropical Storm Allison
This is a Follow-up announcement to the June 13, 2001 edition of the NIH Guide to Grants and Contracts on delay of applications due to Tropical Storm Allison. NIH will consider requests for administrative supplements for extensions in time that include personnel costs, and replacement of equipment, supplies and unique resources damaged or lost as a result of the storm. These requests should be submitted using the PHS-398 face page, budget page, and budget justification page. The application should state that the requested support does not represent a duplication of benefits, e.g., from insurance. The request should be sent to the Grants Management Officer at the funding Institute or Center that is responsible for that grant. (The supplemental package should not be sent to the Center for Scientific Review.) NIH will also continue to accept applications that were intended for the July 1 receipt date. Applications delayed due to flooding should include a cover letter noting the reason for the delay. It is not necessary to get advance permission for a delayed submission. This has also been announced in the 06/22/2001 NIH Guide Notice.
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June 20, 2001: Tropical Storm Allison Disaster Relief
The National Institutes of Health wishes to inform institutions in the Houston area who suffered damage or destruction to facilities, equipment, and/or supplies as a result of Tropical Storm Allison, of the procedure to follow to seek assistance to repair the damage. The Federal Emergency Management Agency (FEMA) is working with the Texas Division of Emergency Management's (DEM), State Public Assistance Office to provide support and assistance to public and private non-profit organizations. Requests must be submitted by organizational officials (not individual investigators) following the instructions that will be provided by the Texas State Public Assistance Office Public and private non-profit institutions are advised to contact:
Mr. Ben Patterson
State Public Assistance Officer
(832)513-4102
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Mr. Richard Boltz
State Coordinating Officer
(832)513-4123 |
The main switchboard for the Disaster Field Office is (832)513-4000. For-profit institutions are advised to contact FEMA at 1(800)462-9029. Also, individuals who have already notified NIH staff of their damages are urged to make sure their institutional officials have initiated contact with the State and/or the Federal Emergency Management Agency, as appropriate. This has also been announced in the 06/21/2001 NIH Guide Notice.
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June 20, 2001: Additional Information on Tropical Storm Allison
Please see the Federal Emergency Management Agency (FEMA) website, located at http://www.fema.gov/, for complete coverage of Tropical Storm Allison.
Also, please City of Houston's BUSINESS DISASTER RELIEF INFORMATION website, located at http://www.ci.houston.tx.us/OEM/, for resources for the City of Houston, Texas. This has also been announced in the 06/21/2001 NIH Guide Notice.
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June 12, 2001: Delays in Grant Application Submission due to Tropical Storm Allison
Some institutions in Texas and Louisiana have had significant damage due to Tropical Storm Allison. The NIH realizes that this may cause problems for investigators who are planning to submit grant applications (both competing and non-competing) for the July 1 receipt date. Applications that are submitted late because of Tropical Storm Allison should include a cover letter noting the reasons for the delay. It is not necessary to get permission in advance for weather-related delays in grant application submission. In addition, Principal Investigators and Program Officials who have experienced damage or losses to their research are encouraged to contact their Program Official about these losses. This has also been announced in the 06/13/2001 NIH Guide Notice and revised in the 06/21/2001 NIH Guide Notice to permit late applications from all applicants and grantees affected by Tropical Storm Allison. NIH will publish a follow-up announcement on resources available to NIH grantees and contractors. (See follow-up 06/22/2001 NIH Guide Notice).
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April 23, 2001: NIH Clarifies Invention Reporting Guidance for Grantees Involved with the VA
In response to concerns raised by a number of recipients of NIH funds, NIH has
reviewed the issue of conflicting reporting requirements when recipients of NIH
funds also have involvement with the Veteran's Administration [Department of
Veteran’s Affairs] (VA). Based on our review and discussions with NIH legal
staff, members of the recipient community and VA and Department of Commerce
officials, NIH has issued the a statement of clarification contained in the
April 23, 2001 NIH Guide Notice.
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April 10, 2001: Workgroups Established to Address Regulatory Burdens
Four workgroups have been established within the Peer Review Oversight
Group/Regulatory Burden Advisory Group to address major current issues
of increasing regulatory burden. Those workgroups will address:
- Institutional Conflicts of Interest(Chair, Dr. Arnold Smith, University of Missouri)
- The Collective Effects of Increasing Regulations and Compensation for the Costs of Compliance (Chair, Dr. Robert Rich, Emory University)
- Human Subjects Protections and IRBs (Chair, Ms. Ada Sue Selwitz, University of Kentucky)
- Animal Welfare Issues (Chair, Dr. Janet Greger, University of Wisconsin)
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April 4, 2001: NIH Announces Outcome of FY2000 Proactive Compliance Site Visits
The National Institutes of Health (NIH) announces the publication of the "Proactive Compliance Site Visits 2000: A Compendium of Findings and Observations." This document is available on the Grants Compliance and Oversight Web page, which is linked on the Office of Extramural Research (OER) homepage (http://grants.nih.gov/grants/oer.htm) under Grant Topics. Also, see the April 4, 2001 NIH Guide announcement for more details.
The Compendium, a result of the ten Proactive Compliance Site Visits (PCSVs) conducted by NIH during FY2000, summarizes the observations and comments from the NIH site visit team as well as institutional observations. NIH is making this document available to the broader biomedical research community as an educational tool to promote awareness of and compliance with NIH policies.
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April 3, 2001: Notice on Required Invention Reporting
As required by the Bayh-Dole Act of 1980, inventions made with federal funding MUST be reported to the Federal sponsor. NIH provides a secure web site to report invention and patent reports, confirmatory licenses, and annual invention utilization reports. For instructions and access to the site, go to http://iedison.gov or call 301-435-1986.
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March 26, 2001: NIH Statement in Response to the NAS Report
The NIH Statement in Response to the NAS Report: Addressing the Nation's Changing Needs For Biomedical and Behavioral Scientists is now available. The National Institutes of Health (NIH) has analyzed the recently issued report from the National Academy of Sciences (NAS), Addressing the Nation's Changing Needs for Biomedical and Behavioral Scientists and has prepared a statement that describes NIH intentions to implement selected recommendations. The NIH offers this statement for comment in order to determine the views of the extramural community prior to implementation. The original NAS report can be found at http://grants.nih.gov/training/nas_report/index.htm
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March 22, 2001: Corrections and Clarifications to NIH Grants Policy Statement (Rev. 03/01)
Please see the NIH Guide Notice of March 20, 2001 for corrections and clarifications to the revised NIH Grants Policy Statement (NIHGPS) which was revised effective March 1, 2001.
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March 12, 2001: One Stop Shopping for NIH Information on Human Subjects and Financial Conflict of Interest
- Guide Notice: Data Safety Monitoring for Phase I and II Trials, June 12, 1998 http://grants.nih.gov/grants/guide/notice-files/not98-084.html
- Guide Notice: Required Education, June 9, 2000 http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-039.html
- Guide Notice: Further Guidance on Data and Safety Monitoring, June 9, 2000 http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-038.html
- Guide Notice: Financial Conflict of Interest (CoI), June 9, 2000 http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-040.html
- Guide Notice: Reporting Adverse Events, June 11, 1999 http://grants.nih.gov/grants/guide/notice-files/not99-107.html
- Guide Notice: Letters or Notices from FDA, Sept. 22, 2000 http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-053.html
- Bioethics Web Site, launched 1999 and continuously updated http://www.nih.gov/sigs/bioethics/index.html
- PA for Short Term Courses in Research Ethics (T15 grants) was issued on January 22, 1999, with 15 awards made to date http://grants.nih.gov/grants/guide/pa-files/PAR-98-005.html
- PA for Mentored Scientist Development Award in Research Ethics was issued on January 22, 1999 to increase training in this area, made 8 awards to date. http://grants.nih.gov/grants/guide/pa-files/PA-99-050.html
- PA for investigator initiated research on Ethical Issues in Human Studies was issued on March 31, 1999 to increase empirical research in this area http://grants.nih.gov/grants/guide/pa-files/PA-99-079.html
- RFA for International Bioethics Education and Career Development Award was issued on March 13, 2000. http://grants.nih.gov/grants/guide/rfa-files/RFA-TW-00-008.html
- National Conference on Human Subject Protection and Financial Conflicts of Interest, Aug. 15-16, 2000, Natcher Center, NIH, Bethesda, MD (cosponsored with DHHS, CDC, and FDA)
- PROG will discuss institutional CoI.
- Computer Based Training Program on the Protection of Human Research Subjects is a one-hour course that was made available to extramural researchers in January 2001 through the NIH web site at http://cme.nci.nih.gov
- Computer Based Training Program for NIH IRB Members made available for public use http://ohsr.od.nih.gov/irb_cbt/
- Annual 8 week course on Ethical and Regulatory Aspects of Human Subjects Research is also available on line at http://www.cc.nih.gov
- Two NIH Regional Seminars are conducted annually. Each regional seminar includes plenary/breakout sessions on CoI. Upcoming seminars to be hosted by:
- University of Texas System - Houston, March 15-16, 2001
- Oregon Health Sciences University - Portland , June 7-8, 2001
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February 28, 2001: Extension of Current PHS 398, 2590 and Related Forms
The Application for a Public Health Service Grant (PHS 398) and Application for Continuation of a Public Health Service Grant (PHS 2590) currently in use were revised February 28, 1998 and approved for use through February 28, 2001. The forms have again been revised and action has been taken for submission to the Office of Management and Budget (OMB). In the interim, until approval is granted from the OMB and until further notice, the current versions of the PHS 398 and 2590 should be used. See 02/28/2001 NIH Guide Notice for further details and contact information.
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February 27, 2001: Publication of the Revised NIH Grants Policy Statement
The National Institutes of Health (NIH) is pleased to announce the revision of the NIH Grants Policy Statement (NIHGPS). The NIHGPS is effective for all NIH grants and cooperative agreements with budget periods beginning on or
after March 1, 2001, and will supersede, in its entirety, the NIH Grants Policy Statement (10/98) as a standard term and condition of award. See 02/27/2001 NIH Guide for description and notable changes since the 1998 verson. Note that this document will not be printed by NIH. See NIHGPS link above for downloading a PDF version of the entire document.
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January 12, 2001: FY 2001 Announcements on Salary Cap, NRSA Stipend Levels and Application Format
This is to bring to your attention three important announcements in the NIH Guide for Grants and Contracts for the week ending January 12, 2001. The first involves the Salary Limitation on Grants, Cooperative Agreements and Contracts in FY 2001 and provides detailed information on changes from last Fiscal Year. The second concerns a National Research Service Award (NRSA) Stipend Increase and Other Budgetary Changes Effective for Fiscal Year 2001. Lastly, NIH has provided guidance on the Format of Grant and Cooperative Agreement Applications Submitted to NIH. Please review these notices and distribute widely among your institutions and organizations.
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