Chemical Sampling Information (CSI)
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• NAME
• SYNONYM(S)
• IMIS
• CAS
• NIOSH
• DOT
• DESCRIPTION
• INCOM

• OSHA GENERAL INDUSTRY PEL
• OSHA CONSTRUCTION INDUSTRY PEL
• ACGIH TLV
• NIOSH REL
• AIHA Weel

• NTP
• IARC
• SYMPTOM(S)
• HEALTH EFFECTS
• ORGAN
• HEALTH GUIDELINE

• PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1)
• SECONDARY SAMPLING/ANALYTICAL METHOD (SAM2)
• COND
• ART
• WIPE

MW:	molecular weight
VP:	vapor pressure, (mm = mm Hg at 20°C or other specific temperature listed, also 1 mm Hg = 1.333224 E+2 Pa)
ATM:	atmosphere, 760 mmHg at 0°C
UEL:	upper explosibility limit
SP GR:	specific gravity
MOLFM:	molecular formula
BP:	boiling point
FP:	flash point

Known To Be Human Carcinogen (also known as HUMAN CARCINOGEN):
There is sufficient evidence of carcinogenicity from studies in humans * , which indicates a causal relationship between exposure to the agent, substance, or mixture, and human cancer.

Reasonably Anticipated to be a Human Carcinogen (also know as SUSPECT HUMAN CARCINOGEN):
There is limited evidence of carcinogenicity from studies in humans * , which indicates that causal interpretation is credible, but that alternative explanations, such as chance, bias, or confounding factors, could not adequately be excluded,
or

there is sufficient evidence of carcinogenicity from studies in experimental animals, which indicates there is an increased incidence of malignant and/or a combination of malignant and benign tumors (1) in multiple species or at multiple tissue sites, or (2) by multiple routes of exposure, or (3) to an unusual degree with regard to incidence, site, or type of tumor, or age at onset,
or

there is less than sufficient evidence of carcinogenicity in humans or laboratory animals; however, the agent, substance, or mixture belongs to a well-defined, structurally related class of substances whose members are listed in a previous Report on Carcinogens as either known to be a human carcinogen or reasonably anticipated to be a human carcinogen, or there is convincing relevant information that the agent acts through mechanisms indicating it would likely cause cancer in humans.

*This evidence can include traditional cancer epidemiology studies, data from clinical studies, and/or data derived from the study of tissues or cells from humans exposed to the substance in question that can be useful for evaluating whether a relevant cancer mechanism is operating in people.

Group 1: The agent (mixture) is carcinogenic to humans.
The exposure circumstance entails exposures that are carcinogenic to humans.

Group 2
Group 2A: The agent (mixture) is probably carcinogenic to humans.
The exposure circumstance entails exposures that are probably carcinogenic to humans.
Group 2B: The agent (mixture) is possibly carcinogenic to humans.
The exposure circumstance entails exposures that are possibly carcinogenic to humans.

Group 3: The agent (mixture or exposure circumstance) is not classifiable as to its carcinogenicity to humans.

Group 4: The agent (mixture) is probably not carcinogenic to humans.

CODE	HEALTH EFFECTS
HE1	Cancer---Currently regulated by OSHA as carcinogen
HE2	Chronic (Cumulative) Toxicity---Known or Suspected animal or human carcinogen, mutagen (except Code HE1 chemicals)
HE3	Chronic (Cumulative) Toxicity---Long-term organ toxicity other than nervous, respiratory, hematologic or reproductive
HE4	Acute Toxicity---Short-term high risk effects
HE5	Reproductive Hazards---Teratogenesis or other reproductive impairment
HE6	Nervous System Disturbances---Cholinesterase inhibition
HE7	Nervous System Disturbances---Nervous system effects other than narcosis
HE8	Nervous System Disturbances---Narcosis
HE9	Respiratory Effects Other Than Irritation---Respiratory sensitization (asthma or other)
HE10	Respiratory Effects Other Than Irritation---Cumulative lung damage
HE11	Respiratory Effects---Acute lung damage/edema or other
HE12	Hematologic (Blood) Disturbances---Anemias
HE13	Hematologic (Blood) Disturbances---Methemoglobinemia
HE14	Irritation-Eyes, Nose, Throat, Skin---Marked
HE15	Irritation-Eyes, Nose, Throat, Skin---Moderate
HE16	Irritation-Eyes, Nose, Throat, Skin---Mild
HE17	Asphyxiants, Anoxiants
HE18	Explosive, Flammable, Safety (No adverse effects encountered when good housekeeping practices are followed)
HE19	Generally Low Risk Health Effects---Nuisance particulates, vapors or gases
HE20	Generally Low Risk Health Effects---Odor

MEDIA, sampling media.

ANL SOLVENT, Analytical solvent used in referenced method for desorption or extraction. If compounds to be sampled use the same medium and also use the same analytical or alternate solvent, they may be analyzed from the same sample.

ALT SOLVENT, Alternate solvent for desorption or extraction evaluated at Salt Lake Technical Center. If compounds to be sampled use the same medium and also use the same analytical or alternate solvent, they may be analyzed from the same sample.

Volumes listed are guidelines but should not be exceeded for solid sorbents.
 
MAX V, maximum volume
MAX F, maximum flow rate
MIN V, minimum volume
REC V, recommended volume
REC F, recommended flow rate
MIN T, minimum time
CAPTURE R, capture rate
ANL 1, current Salt Lake Technical Center analytical method

ANL A, alternate Salt Lake Technical Center analytical method

REF, method reference. (numbered, as listed in both SLC1 and SAM2)

1. NIOSH MANUAL OF ANALYTICAL METHODS (NMAM®), 4^th Ed., DHHS (NIOSH) Publication no. 94-113 (August, 1994); 1^st Supplement, DHHS (NIOSH) Publication no. 96-135; 2^nd Supplement, DHHS (NIOSH) Publication no. 98-119; and 3^rd Supplement, DHHS (NIOSH) Publication no. 2003-154; Schlecht, P.C. and O'Connor, P.F., (pfo1@cdc.gov) Eds. Also, NIOSH MANUAL OF ANALYTICAL METHODS, 2^nd Ed., Volume 1-7, Taylor, D.G., Ed. DHHS, National Institute for Occupational Safety and Health, Cincinnati, Ohio. Current NIOSH methods are available online.
2. OSHA MANUAL OF ANALYTICAL METHODS, USDOL OSHA Salt Lake Technical Center (SLTC), 8660 South Sandy Parkway, Sandy, UT 84070-6406. Sampling and Analytical Methods are available at this website.
3. McLean, J.D. and Holland, J.F.: Development of a Portable Polarograph for Determination of Aldehydes in Automotive Exhaust and Production Plant Samples. ENVIRONMENTAL SCIENCE AND TECHNOLOGY, Vol. 9, pp. 127-131, (1975).
4. Mattocks, A.R.: Spectrophotometric Determination of Pyrazoline and Some Acrylic Amides and Esters. ANAL. CHEM., Vol. 40, pp. 1347, (1968).
5. ANALYSIS OF PESTICIDE RESIDUES IN HUMAN AND ENVIRONMENTAL SAMPLES. EPA, Pesticide and Toxic Substances Effects Laboratory, Research Triangle Park, N.C., (1974).
6. ORION ELECTRODE INSTRUCTION MANUAL. Orion Research, Inc., Cambridge, Mass., (1971).
7. Thomsen, E. and Stern, R.M.: A Simple Analytical Technique for the Determination of Hexavalent Chromium in Welding Fumes and other Complex Materials. The Danish Welding Institute Report No. 79-01, SCAND. J. WORK. ENVIRON. & HEALTH, Vol. 5, pp. 386-403, (1979).
8. THE INDUSTRIAL ENVIRONMENT--ITS EVALUATION AND CONTROL. DHHS, National Institute for Occupational Safety and Health, Washington, D.C., (1973).
9. Brief, R.S., Venable, F.L.S., and Ajemian, R.S.: Nickel Carbonyl: Its Detection and Potential for Formation. Amer. Ind. Hyg. Assn. J., Vol. 26, pp. 72-76, (1965).
10. King, J.R., Nony, C.R., and Boeman, M.C.: Trace Analysis Diethylstilbestrol (DES) in Animal Chow by Parallel High-Speed Liquid Chromatography, Electron-Capture Gas Chromatography, and Radioassays. J. CHROMATOGRAPHIC SCIENCE, Vol. 15, pp. 14, (1977).
11. OSHA TECHNICAL MANUAL (OTM), OSHA Instruction CPL 2-2.20B, USDOL OSHA Directorate of Technical Support, Washington, D.C. (1990). Current OSHA Technical Manual (OTM) (TED 01-00-015 [TED 1-0.15A]) is available at this website.
12. OCCUPATIONAL EXPOSURE SAMPLING STRATEGY MANUAL (77-173), DHHS, National Institute for Occupational Safety and Health, Cincinnati, Ohio, (1977).
13. Brief, R.S., Ajemian, R.S., and Confer, R.G.: Iron Pentacarbonyl: Its Toxicity, Detection, and Potential for Formation. AMER. IND. HYG. ASSN. J., Vol. 28, pp. 21-30, (1967).
14. Wisconsin Occupational Health Laboratory (WOHL), 2601 Agriculture Drive, Madison, Wis. 53718, (800)446-0403. There are several substances in which WOHL methods differ from the OSHA method or an OSHA method does not exist. For more information concerning these methods, please contact WOHL
15. U.S. Code of Federal Regulations (CFR), Title 29, Part 1910, U.S. Government Printing Office, Washington, D.C.
16. Eller, P.E.: Determination of Nickel Carbonyl by charcoal tube collection and furnace atomic absorption spectrophotometry. APPL. IND. HYG. (1)3. Sept 1986 pp 115-118.
17. Follow Manufacturer's Instruction Sheet. SLTC has not evaluated this product.

SAE, Sampling and Analytical Error. SAE is a measure of the precision and accuracy of the combined sampling and analytical process. The SAEs in this file are historical in nature and are not valid for current use. For current SAEs, contact the laboratory that analyzed your samples.

CLASS, method classifications.

The following method status classifications have been assigned to OSHA methods. Some of the classifications are obsolete, but will be encountered in various OSHA methods. NIOSH method classification is taken from the method evaluation status published in their methods.

Note special instructions on sampling or obtaining sampling media from the Salt Lake Technical Center. These instruction pertain to OSHA and 18(b) or 7(c)(1) state programs.

ANL, any analytical method used in conjunction with a secondary sampling method. Some of these are NIOSH methods which are not in use by Salt Lake Technical Center.

For other subheadings see Primary Sampling/Analytical Method(SLC1) above.

DET TUBE, Detector Tubes are used for screening to determine whether additional sampling is needed. If detector tube readings exceed 1/2 the PEL, CSHOs should sample with the SLC1 method, if available. Under certain conditions, detector tubes can be used for compliance purposes. Contact SLTC for further information.

NOTE: OSHA has evaluated detector tubes for internal use; however, the number and type of tubes is limited. OSHA evaluates detector tubes primarily to select tubes for OSHA use. OSHA does not certify detector tubes, nor endorse products of any manufacturer. The Safety Equipment Institute certifies detector tubes and more information regarding their program can be found at their www.seinet.org site. Omission of other manufacturers tubes does not mean the tubes have been found unsatisfactory.

CODE OF FEDERAL REGULATIONS (CFR) TITLE 29 PART 1910, USDOL, OSHA, Washington, D.C. Also available U.S. Government Printing Office, Washington, D.C.

HAWLEY'S CONDENSED CHEMICAL DICTIONARY, FOURTEENTH EDITION, Van Nostrand Co., New York, 2001.

IARC MONOGRAPHS ON THE EVALUATION OF THE CARCINOGENIC RISK OF CHEMICALS TO HUMANS. International Agency for Research on Cancer, Lyon, France. (90+ volumes). Available WHO Publications Centre USA, 49 Sheridan Ave., Albany, N.Y. 12210.

THE MERCK INDEX, FOURTEENTH EDITION, Merck & Co., Rahway, N.J., 2006.

NIOSH REGISTRY OF TOXIC EFFECTS, DHHS, National Institute for Occupational Safety and Health, Cincinnati, OH. Available U.S. Government Printing Office, Washington, D.C.

NIOSH POCKET GUIDE TO CHEMICAL HAZARDS, DHHS, National Institute for Occupational Safety and Health, Cincinnati, OH. September, 2005, DHHS (NIOSH) 2005-149. Available U.S. Government Printing Office, Washington, D.C.

NIOSH/OSHA HEALTH GUIDELINES, DHHS, DOL, Washington, D.C., January, 1981, DHHS (NIOSH) No. 81-123. Available U.S. Government Printing Office, Washington, D.C. Current listing of NIOSH Health Guidelines.

ELEVENTH REPORT ON CARCINOGENS. DHHS, National Toxicology Program, Washington, D.C.

TOXIC SUBSTANCES CONTROL ACT INVENTORY, U.S. Environmental Protection Agency, Washington, D.C. Additional information is available online from EPA.